SOCS5 (NM_014011) Human Untagged Clone

CAT#: SC110087

SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1


  "NM_014011" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SOCS5
Synonyms CIS6; Cish5; CISH6; SOCS-5
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110087 sequence for NM_014011 edited (data generated by NextGen Sequencing)
ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGT
CATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTC
AAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGA
GAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATTCTTCAAGGAGAAATCAA
AATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCGAAAAGGATAATGATTCT
TGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACATGCTCCATGG
GGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA
AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCT
GTACACGACATGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGG
TTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCT
CTCTTTTCCAATAAAAGAAAAATCCATCTCTCTGAATTAATGCTTGAGAAATGCCCTTTT
CCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTAAACAGCATACAGCTCCTGTG
AGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTACAGAAGATGAA
GAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC
AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGA
CCAAAATTAGCTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCT
AATTGTGACTCGGAAGAGGATACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAG
CGTCAGATATCTGGAGACAGCCATACGCATGTTAGCAGACAGGGAGCTTGGAAAGTCCAC
ACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGCTTCAAATTACAGGGAATCCC
TGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGGGAAACCTGAA
GGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC
CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGAC
GCCCATGACCCGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAA
GATCCCAGTTCGTGCATGTTTTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTC
CCTTTTAGCCTGCAGTATATCTGTCGCGCGGTAATCTGCAGGTGCACTACGTATGATGGA
ATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTTTAAAAGAGTATCATTATAAA
CAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAGTAA

Clone variation with respect to NM_014011.4
1047 c=>g
>OriGene 5' read for NM_014011 unedited
NGTTCAGATTTGTATACGATGACTATAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCC
GAATTCGGCACGAGGGACGCACCGGAGGGCAGGCGGACTCGCCCTGTCGGTGACTGCGCC
GTCCGGGCCCGTCCTGCCTGGCCGCAGGTGCCCTGGATGAGGCCGCCCCGCGCGCCCCAA
ACGATTTTATAATCAATGGATAAAGTGTGTTATATGTGGAATAACTTCAAATACAGGTGT
CAGAATCTCTTCGGTCATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCAAC
AGATGTTTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAACAA
AGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATTCT
TCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCGAA
AAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCT
CGACATGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCA
TTGGATGCTGATAAAAAGTTTGATAGAACTCGAAGTGGACTTCAAAGGAGAGAGACGCGC
TACCGCGTAAGTTCTGTACACGACATGGACAGTGTTTCCCGCAGAACTGTANGAAGTCGC
TCTCTAACACAGAGTTGCACGATACCGCGGGCTTGCGCTTCTCCACTGAGACTTACAGAA
GCAGTCACAAGCCTTCTTTTTCAATAAAAGAAAACCCTCTCTCTGAATTAAGCTTGAAAA
AGCCCCTATACTGCTGGCTTAAATTAGCCCAAAATGGCCTTTGGTTAAACACATACCGCT
CC
>OriGene 3' read for NM_014011 unedited
NNNNTTTAGCTTTGAACCGGCGGCCGCATNCTAAGATCGAGTTTTTTTTTTTTTTTTTTG
CAAGTTCATGCTGGTGATTTTTCTTTTTTAAAAGTAAGCCACTAATATTTTAAGACAAAA
ATTTAAACCAAAAATTGCATATTAATATTATACACAAACTGAAACATGTGACTTTTAGCA
CAGTGTATACATGCTTACATAAACTCAAACACATTTAAAACAATTTCCATTTAACATATG
AAAGTTTTGAAATACATAAAAGCATTAATACTTTCTATAAAACTACAGTTAGAACATCAA
TTTGCTACAAGCATATAAAAACATCAAGTGCTTTCTTGGAGTTTCAAGTTTCCTCTCTAA
AACACAATCTTGCTCACATATATAGTCCTTTTCCAATAATCAGTATGAACTTTTCTTTTT
CTCAAGAGGTTTATTTTCCAGGTACATTATAAGCTCAAGAAAAAAGACCCAACAATTAGG
CAATATAATTATGTCATAACAACTTAATTGCACATAATGCTTTAAAGTAGGTTTGGATGA
AGTTCTCAAACACTTTGGTATATGATCTTCAGGGACTTTAATTAGAAACAACAGAAATTA
AAAGTCCCTTCAATCCCCATTTTGCTTTAAAAGGGACAAGTCTTTGGTTAAAGTTCTACA
TTTTGGGCATTTATTTTTAATTAAGATGGTCCCCAAACCAATAAATGGTACTGATCTATT
ACAAATTCACAAGACTTCATTTAACCTGCTTCTGATGCAGTGGGAGGTTACAGATACTCA
TTTACTATAATATGTCATTGGATAGTTTCAATCTTTCATTTATAAGCAGAGAAATCAATA
NGGTTATTACTTCTCTGTCAGTTTTCTGTTATAACCTAAACTGTACANGTATTTGCAGTA
ACTACC
Restriction Sites NotI-NotI     
ACCN NM_014011
ORF Size 1611 bp
Insert Size 4760
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_014011.4, NP_054730.1
RefSeq Size 4422
RefSeq ORF 1611
Locus ID 9655
Domains SH2, SOCS
Protein Families Druggable Genome
Protein Pathways Jak-STAT signaling pathway
Gene Summary The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Both variants encode the same protein.

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