Ubiquilin (UBQLN1) (NM_013438) Human Untagged Clone

CAT#: SC110414

UBQLN1 (untagged)-Human ubiquilin 1 (UBQLN1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBQLN1
• Synonyms: DA41; DSK2; PLIC-1; UBQN; XDRP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110414 sequence for NM_013438 edited (data generated by NextGen Sequencing)
  ATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCC
  GAAGGTGCTGGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACC
  GTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAG
  TTTAAGGAAGAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTT
  GCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTT
  ACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACA
  AATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGT
  TCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTTGCAGGTCTGAGTAGC
  TTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTG
  TCTAACCCTGAAATGATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCA
  AATCCTGACCTGATGAGACAGTTAATTATGGCCAATCCACAAATGCAGCAGTTGATACAG
  AGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAA
  CTTGTCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGC
  AACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATGTACACAGATATTCAG
  GAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTG
  AGCAATACATCCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTA
  CCCAATCCATGGGCTCCACAGACTTCCCAGAGTTCATCAGCTTCCAGCGGCACTGCCAGC
  ACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCG
  CCAAATTTGGTGCCTGGAGTAGGAGCTAGTATGTTCAACACACCAGGAATGCAGAGCTTG
  TTGCAACAAATAACTGAAAACCCACAACTTATGCAAAACATGTTGTCTGCCCCCTACATG
  AGAAGCATGATGCAGTCACTAAGCCAGAATCCTGACCTTGCTGCACAGATGATGCTGAAT
  AATCCCCTATTTGCTGGAAATCCTCAGCTTCAAGAACAAATGAGACAACAGCTCCCAACT
  TTCCTCCAACAAATGCAGAATCCTGATACACTATCAGCAATGTCAAACCCTAGAGCAATG
  CAGGCCTTGTTACAGATTCAGCAGGGTTTACAGACATTAGCAACGGAAGCCCCGGGCCTC
  ATCCCAGGGTTTACTCCTGGCTTGGGGGCATTAGGAAGCACTGGAGGCTCTTCGGGAACT
  AATGGATCTAACGCCACACCTAGTGAAAACACAAGTCCCACAGCAGGAACCACTGAACCT
  GGACATCAGCAGTTTATTCAGCAGATGCTTCAGGCTCTTGCTGGAGTAAATCCTCAGCTA
  CAGAATCCAGAAGTCAGATTTCAGCAACAACTGGAACAACTCAGTGCAATGGGATTTTTG
  AACCGTGAAGCAAACTTGCAAGCTCTAATAGCAACAGGAGGTGATATCAATGCAGCTATT
  GAAAGGTTACTGGGCTCCCAGCCATCATAG
  
  Clone variation with respect to NM_013438.4
  725 c=>t;1170 g=>t;1590 g=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013438 unedited
  AAACCAATTCCCACGAGGCCTCGTGCCGTATTCGGCACGAGGGTCGGTGTGAGCGAGCGG
  CGCCTGAACACACGGCGGCTGCCGAGCGCCTGACCCGGGCCTGCGCCAGAGCCTGCACCG
  AGCTCCGGGGCCCCACACCCGCTACCGTGGCCCTGCGCCCGTTGCTACTGAGGCTTCNGT
  CNCTGCATTCTTCGCTGTCCAGGCCTGCCGGCTCTGGTGTCTGCTGGCTCCTCCTTGCTC
  GCCTGCTCCCTCCTGCTTGCCTGATTCACCGCCGCCGCCGCCGCCACAGCCATGGCCGAG
  AGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCT
  GGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACC
  CCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAA
  GAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAA
  ATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCAC
  CTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCT
  GGAAGCAATGTTACTACATTCATCACTCCCTATAGTAACTCTACATCTGGTTCTGCTACT
  AACAACCCTTTTGGGTTAAGTGGCCCTGGGGGGACTTGCAGGTCTGAATAACCTTGGGGT
  TGAATACTACCCACTTCTTTGAACTACCGAATCAGATGCCGCGACACCTTTTGCCTAACC
  TGAAAGATGGTCCCATCATGGAAAACCCTTTTGTTCAAACATGCCCTCAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013438 unedited
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAACATTTCAATTAC
  AAATTTTAATGCCTGTTAAACTACCTATGGGAGAAGCTGAGAAGTCCTAGGCAAATGCAC
  TTTGGGGTATACTACAGTGTTCCTTCAGTCTGCACAAAGATTAAGGTAATTTACAGTCAA
  TCTGTGAATGAATGTTGAGACAATGTTACATTATGTGTCTGTACAATTAATTGTCCTTAA
  AGAGATAACCAGAATCAGCTTTTCTACTGTATTTTCAACAAACCTGACTAACCGGCACTT
  TTGCTGGGAGATGTTTGTCAAAGATGCTGTAAGATTCTATACAATTAGGAAATACTCAGC
  TTTAAGAGTATTTTCTTATCTTCACTTTTTTAGTTACAGGTGTTTTGCTCAGAGAGCCTA
  TTGCAGTATGTTTCCAGAAATGCAGTCCCAAATGTGCATACTCTATATTGTATACAAATA
  AAACAAAATTATCAGTAGTATAAATCTTACAGCATTGTTTGCAAAAATGCATGCCAAAGT
  CACAATAAGCAATACTGTACCACAAATTATAGAGTGCAAATGATTTGCTTCTTTTTAATG
  CTTTTATTCTACATAAATTACTACCATAGGCTAATGTTTAAAAAGCAAATAAACTGGACA
  GATGCAGGACAAAATCTGGTCACCCAACTATAAAAGGTGATGTTTTTAAAAAATTACAAT
  AAATGCAGAAGTGATGCATGCAGTAGCCTTAATTCCCACTNGTCCAGAAAAGAAAATACA
  GAAAAACCACACATCTTACTGTACTNCACCTTTAAATGCATCATATNNTGGTTTGTTATT
  ACAGCACAGAATTCCCAGAGTCAAAATGAAATANAGCAGGTATTTTAAAGTTNAANGACC
  NNGTATCAAAATAAATTACATNTTTTCAAGATACAGAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013438
• ORF Size: 1770 bp
• Insert Size: 2840
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013438.3, NP_038466.2
• RefSeq Size: 3952
• RefSeq ORF: 1770
• Locus ID: 29979
• Domains: UBA, UBQ, STI1
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).