AVPR1A (NM_000706) Human Untagged Clone

CAT#: SC110836

AVPR1A (untagged)-Human arginine vasopressin receptor 1A (AVPR1A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AVPR1A
• Synonyms: AVPR1; AVPR V1a; V1aR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000706, RT-PCR generated
  ATGGACAGCATGCGTCTCTCCGCCGGTCCCGACGCGGGGCCCTCGGGCAACTCCAGCCCA
  TGGTGGCCTCTGGCCACCGGCGCTGGCAACACAAGCCGGGAGGCCGAAGCCCTCGGGGAG
  GGCAACGGCCCACCGAGGGACGTGCGCAACGAGGAGCTGGCCAAACTGGAGATCGCCGTG
  CTGGCGGTGACTTTCGCGGTGGCCGTGCTGGGCAACAGCAGCGTACTGCTGGCTCTGCAC
  CGGACGCCGCGCAAGACGTCCCGCATGCACCTCTTCATCCGACACCTCAGCCTGGCCGAC
  CTGGCCGTGGCATTCTTCCAGGTGCTGCCGCAAATGTGCTGGGACATCACCTACCGCTTC
  CGCGGCCCCGACTGGCTGTGCCGCGTGGTGAAGCACCTGCAGGTGTTCGGCATGTTCGCG
  TCGGCCTACATGCTGGTAGTCATGACAGCCGACCGCTACATCGCGGTGTGCCACCCGCTC
  AAGACTCTGCAACAGCCCGCGCGCCGCTCGCGCCTCATGATCGCGGCCGCCTGGGTGCTG
  AGCTTCGTGCTGAGCACGCCGCAGTACTTCGTCTTCTCCATGATCGAGGTGAACAATGTC
  ACCAAGGCCCGCGACTGCTGGGCCACCTTCATCCAGCCCTGGGGTTCTCGTGCCTACGTG
  ACCTGGATGACGGGCGGCATCTTTGTGGCGCCCGTGGTCATCTTGGGTACCTGCTACGGC
  TTCATCTGCTACAACATCTGGTGCAACGTCCGCGGGAAGACGGCGTCGCGCCAGAGCAAG
  GGTGCAGAGCAAGCGGGTGTGGCCTTCCAAAAGGGGTTCCTGCTCGCACCCTGTGTCAGC
  AGCGTGAAGTCCATTTCCCGGGCCAAGATCCGCACGGTGAAGATGACTTTTGTGATCGTG
  ACGGCTTACATCGTCTGCTGGGCGCCTTTCTTCATCATCCAGATGTGGTCTGTCTGGGAT
  CCCATGTCCGTCTGGACCGAATCGGAAAACCCTACCATCACCATCACTGCATTACTGGGT
  TCCTTGAATAGCTGCTGTAATCCCTGGATATACATGTTTTTTAGTGGCCATCTCCTTCAA
  GACTGTGTTCAAAGCTTCCCATGCTGCCAAAACATGAAGGAAAAATTCAACAAAGAAGAT
  ACTGACAGTATGAGCAGAAGACAGACTTTTTATTCTAACAATCGAAGCCCAACAAACAGT
  ACGGGTATGTGGAAGGACTCGCCTAAATCTTCCAAGTCCATCAAATTCATTCCTGTTTCA
  ACTTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000706 unedited
  NNNGGTGAAGTCATAATTGTATACGACTCACTAAGGCGGCCGACGAATTCGCTTAGTAGG
  AGCTGCATGGACAGCATGCGTCTCTCCGCCGGTCCCGACCGGGGCCCTCGGGCAACTCCA
  GCCCATGGTGGCCTCTGGCCACCGGCGCTGGCAACACAAGCCGGGAGGCCGAAGCCCTCG
  GGGAGGGCAACGGCCCACCGAGGGACGTGCGCAACGAGGAGCTGGCCAAACTGGAGATCG
  CCGTGCTGGCGGTGACTTTCGCGGTGGCCGTGCTGGGCAACAGCAGCGTACTGCTGGCTC
  TGCACCGGACGCCGCGCAAGACGTCCCGCATGCACCTCTTCATCCGACACCTCAGCCTGG
  CCGACCTGGCCGTGGCATTCCTCCAGGTGCTGCCGCAAATGTGCTGGGACATCACCTACC
  GCTTCCGCGGCCCCGACTGGCTGTGCCGCGTGGTGAAGCACCTGCAGGTGTTCGGCATGT
  TCGCGTCGGCCTACATGCTGGTAGTCATGACAGCCGACCGCTACATCGCGGTGTGCCACC
  CGCTCAAGACTCTGCAACAGCCCGCGCGCCGCTCGCGCCTCATGATCGCGGCCGCCTGGG
  TGCTGAGCTTCGTGCTGAGCACGCCGCAGTACTTCGTCTTCTCCATGATCGAGGTGAACA
  ATGTCACCAAGGCCCGCGACTGCTGGGCCACCTTCATCCAGCCCTGAGGTTCTCGTGCCT
  ACGTGACCTGNATGACGGGCGGCATCTTTGTGGCGCCCGTGGTCATCTTGAGTACCTGCT
  ACGGCTTCATCTGCTACACATCTGGGTGCACGTCCGCGGGGAGACGGCGTCGCGCCAGAG
  CAAGGGTGCAGAGCAAGCGGGTGTTGGCCTTCAAAAGGGGTTTCTGCTNGCACCTGTGTC
  AGCAGCGTGGAGTCCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000706 unedited
  CTGGCTATGGCGATGGCACTCTCCAGGGCCAGGATAGCACTGGGGNAGGGTCACAGGCAG
  CCACCCGGGCATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTATAGTCGACAA
  GCTTGATATCGGTACCAGATCTGAATTCGGCTTCAAGAATCAAGTTGCATGAATGCAAGG
  CTCAAGTTGAAACAGGAATGAATTTGATGGACTTGGAAGATTTAGGCGAGTCCTTCCACA
  TACCCGTACTGTTTGTTGGGCTTCGATTGTTAGAATAAAAAGTCTGTCTTCTGCTCATAC
  TGTCAGTATCTTCTTTGTTGAATTTTTCCTTCATGTTTTGGCAGCATGGGAAGCTTTGAA
  CACAGTCTTGAAGGAGATGGCCACTAAAAAACATGTATATCCAGGGATTACAGCAGCTAT
  TCAAGGAACCCAGTAATGCAGTGATGGTGATGGTAGGGTTTTCCGATTCGGTCCAGACGG
  ACATGGGATCCCAGACAGACCACATCTGGATGATGAAGAAAGGCGCCCAGCAGACGATGT
  AAGCCGTCACGATCACAAAAGTCATCTTCACCGTGCGGATCTTGGCCCGGGAAATGGACT
  TCACGCTGCTGACACAGGGTGCGAGCAGGAACCCCTTTTGGAAGGCCACACCCGCTTGCT
  CTGCACCCTTGCTCTGGCGCGACGCCGTCTTCCCGCGGACGTTGCACCAGATGTTGTAGC
  AGATGAAGCCGTAGCATGTACCCAAGATGACCACGGGCGCCACATAGATGCCGCCCGTCA
  TCCATGTCACGTANGCACGAGAACCCCAGGCTGTATGAATGTGGCCCANCAGTCGCGGGC
  CTTGGTGACATTGTTCACCTCGATCATGGGAGAAAACATATACTGCNGCGTT
  
• Restriction Sites: Please inquire
• ACCN: NM_000706
• Insert Size: 1350 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000706.3, NP_000697.1
• RefSeq Size: 4154 bp
• RefSeq ORF: 1257 bp
• Locus ID: 552
• Cytogenetics: 12q14.2
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
• Gene Summary: 'The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]'