N WASP (WASL) (NM_003941) Human Untagged Clone

CAT#: SC111092

WASL (untagged)-Human Wiskott-Aldrich syndrome-like (WASL)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WASL
• Synonyms: N-WASP; NWASP; WASPB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111092 sequence for NM_003941 edited (data generated by NextGen Sequencing)
  ATGAGCTCCGTCCAGCAGCAGCCGCCGCCGCCGCGGAGGGTCACCAACGTGGGGTCTCTG
  TTGCTCACCCCGCAGGAGAACGAGTCCCTCTTCACTTTCCTCGGCAAGAAATGTGTGACT
  ATGTCTTCAGCAGTGGTGCAGTTATATGCAGCAGATCGGAACTGTATGTGGTCAAAGAAG
  TGCAGTGGTGTTGCTTGTCTTGTTAAGGACAATCCACAGAGATCTTATTTTTTAAGAATA
  TTTGACATTAAGGATGGGAAACTATTGTGGGAACAAGAGCTATACAATAACTTTGTATAT
  AATAGTCCTAGAGGATATTTTCATACCTTTGCTGGAGATACTTGTCAAGTTGCTCTTAAT
  TTTGCCAATGAAGAAGAAGCAAAAAAATTTCGAAAAGCAGTTACAGACCTTTTGGGCCGT
  CGACAAAGGAAATCTGAGAAAAGACGAGATCCCCCAAATGGTCCTAATCTACCCATGGCT
  ACAGTTGATATAAAAAATCCAGAAATCACAACAAATAGATTTTATGGTCCACAAGTCAAC
  AACATCTCCCATACCAAAGAAAAGAAGAAGGGAAAAGCTAAAAAGAAGAGATTAACCAAG
  GCAGATATAGGAACACCAAGCAATTTCCAGCACATTGGACATGTTGGTTGGGATCCAAAT
  ACAGGCTTTGATCTGAATAATTTGGATCCAGAATTGAAGAATCTTTTCGATATGTGTGGA
  ATCTCAGAGGCACAACTTAAAGACAGAGAAACATCAAAAGTTATATATGACTTTATTGAA
  AAAACAGGAGGTGTTGAAGCTGTTAAAAATGAACTGCGGAGGCAAGCACCACCACCTCCA
  CCACCATCAAGGGGAGGGCCACCTCCTCCTCCTCCCCCTCCACACAACTCAGGTCCTCCT
  CCTCCTCCTGCTAGGGGAAGAGGCGCTCCTCCCCCACCACCTTCAAGAGCTCCCACAGCT
  GCACCTCCACCACCGCCTCCTTCCAGGCCAAGTGTAGCAGTCCCTCCACCACCGCCAAAT
  AGGATGTACCCTCCTCCACCTCCAGCCCTTCCCTCCTCAGCACCTTCAGGGCCTCCACCA
  CCACCTCCATCTGTGTTGGGGGTAGGGCCAGTGGCACCACCCCCACCGCCTCCACCTCCA
  CCTCCTCCTGGGCCACCGCCCCCGCCTGGCCTGCCTTCTGATGGGGACCATCAGGTTCCA
  ACTACTGCAGGAAACAAAGCAGCTCTTTTAGATCAAATTAGAGAGGGTGCTCAGCTAAAA
  AAAGTGGAGCAGAACAGTCGGCCAGTGTCCTGCTCTGGACGAGATGCACTGTTAGACCAG
  ATACGACAGGGTATCCAACTAAAATCTGTGGCTGATGGCCAAGAGTCTACACCACCAACA
  CCTGCACCCACTTCAGGAATTGTGGGTGCATTAATGGAAGTGATGCAGAAAAGGAGCAAA
  GCCATTCATTCTTCAGATGAAGATGAAGATGAAGATGATGAAGAAGATTTTGAGGATGAT
  GATGAGTGGGAAGACTGA
  
  Clone variation with respect to NM_003941.2
  57 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003941 unedited
  GGAAGCGTACAAATTTGTAAACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGCC
  GCCGCTGCGGGAGGGTTGGGGGAGGAGTTGGGAGTTTAGCGCAGTCGCCGGAGTGCGAGG
  ACAACGACCATCCGGCCCTAGCCTGGCCGGGCGGGTGCCGGGAGCTTCCCTTTCTCAGCG
  CGGCGCGAAGGTGGCTCGCCGTCAGCGCCTGCTTCCCTCGACCTCGTCCTCCTCCCCGCT
  CCGGAGGAGCTGCGAGATGTGGCGCCTCTGACTCCACTTCTCCCCGCCCCTGTCACCGAG
  AGGGGGAACGAGCTCTCGCCCACTCGCCGGAGGAGACGGCCCTGGACTCCCAACCCCGCC
  GGCGAAACCATGAGCTCCGTCCAGCAGCAGCCGCCGCCGCCGCGGAGGGTCACCAACGTG
  GGGTCTCTGTTGCTCACCCCGCAGGAGAACGAGTCCCTCTTCACTTTCCTCGGCAAGAAA
  TGTGTGACTATGTCTTCAGCAGTGGTGCAGTTATATGCAGCAGATCGGAACTGTATGTGG
  TCAAAGAAGTGCAGTGGTGTTGCTTGTCTTGTTAAGGACAATCCACAGAGATCTTATTTT
  TTAAGAATATTTGACATTAAGGATGGGAAACTATTGTGGGAACAAGAGCTATACAATAAC
  TTTGTATATAATAGTCCTAGAGGATATTTTCATACCTTTGCTGGAGATACTTGTCAAGTT
  GCTCTTAATTTTGCCAATGAAGAAGAAGCANAAAAATTTCGAAAAGCAGTTACAGACCTT
  TTGGGCCGTCGACAAAGGAAATCTGAGAAAAGACGAGATCCCCCAAATGGTCCTAATCTA
  CCATGGCTACAGTTGATATAAAAAATCCAGAAATCACACANATAGATTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003941 unedited
  CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGGTCAAATTAATTTTATT
  ATGCTCCATGATGAATTGCCACCAGTGCAACATCCTATTCACTATACATTTCAAAAAAAG
  AATTCACATACTAAACAAAATTTCAGTTGTCTGAAAATGAAATGATTGAAAGTCTTTATG
  AATCTCATACATACAATATGTGGCTAGCTGAAATTGTCTATCACGTAGCATTTAGATATA
  AAAAGCCTCATGCTAGTTTGTTAAATGCAAAGGCTACCAGACGACCATTTAGCTGGAGAA
  TATACGGAAGGCTTTCAGACAACGCACAGGTATAGTGCTGCTCACAGTGCAGGATGGTAG
  AGGACTGAAACATGCAACCTTACACCTTACTTGGTAAAGCAGATTTAGTCTTCATGCCTG
  GACTGAACTCCACAGCTGCTGTGTTTCAACCAACAGTAATTTAGACTTTTTGTAACAACA
  ACCAATGTCTTTTTCTTCTTTAAGAAAAAAAGAATAAATTAATTACCTTTGGCCAATTAT
  ATATCCCTTTTACATGTTTAAAATTGTGCCTTTGAACTCGCAAAATGGGTACTCTCTGCT
  GAGAGAAGTTCCTGATAAATATATATTTATACCAAAGGCAGCTGGAAAATCTAGAATTTC
  TTTGCCACAAGTTAAGAGAGATCTTAAACTGGCACTTACCCTGGAGAACTTTCCTAGGAA
  ATCTAAAAAGGTTCTTCATCCCGGAAAAAACAAAAAAATTTTCCAATTTACCTTCACTCA
  AAAAAACTATAATGGGCGCTTTTAATTTTTGCCCAACCTTCTGCATTTATTGGCTAACAC
  CTGTCCAACTCCATTTGCCCAAATTCGCTGGGCCTCACCCCCCAAAAATGATGTCTTCCC
  AAAAGGGCTTCTCCACCGAGGGCCCGTTTTCCCCACAAACAAAAGCCACAATTTTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003941
• ORF Size: 1518 bp
• Insert Size: 4540
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003941.2, NP_003932.3
• RefSeq Size: 4430
• RefSeq ORF: 1518
• Locus ID: 8976
• Domains: PBD, WH1, WH2
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
• Gene Summary: This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]