FCP1 (CTDP1) (NM_048368) Human Untagged Clone

CAT#: SC111100

CTDP1 (untagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 (CTDP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTDP1
• Synonyms: CCFDN; FCP1
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_048368, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCCGAGGGCGCCCCGACGGCGGCTGTGGCCGAGGTGCGCT
  GCCCGGGGCCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCGGCCGTGCGCATCGGCTC
  GGTGCTGGCCGTGTTCGAGGCCGCCGCCTCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCC
  GGGGGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAGCGCGCGGGCGTGGTGCGGGAGC
  TGTGCGCGCAGCCGGGCCAGGTGGTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCACCC
  GGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTCACCCAGTTGCAGAGTAAGAACGGGAAG
  CAGCAGGTGCCGCTGTCCACGGCGACCGTGTCCATGGTGCACAGCGTGCCGGAGTTGATGGTGAGCTCCG
  AGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGACTGCACCGAAACCGGAAGCTGGTGCTCATGGT
  GGACTTGGACCAGACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAATAAAGGCATCTTT
  CACTTCCAGCTGGGCCGGGGTGAGCCCATGCTGCACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGG
  AGAAGATCGCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTGTACGCACACACCATCGC
  AGGCTTTTTAGACCCCGAGAAGAAGCTTTTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCA
  TTTTCTAAAACGGGAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCAATGGTTTGCATTATTGATGATC
  GAGAAGATGTCTGGAAGTTTGCCCCCAATCTGATAACTGTGAAGAAATATGTATACTTCCAGGGCACGGG
  TGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGAAAGAAAGTAAATCATTCTCGAGGCACT
  GAGGTCTCAGAGCCATCTCCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTGGAGCCCA
  GCAATGGCCTGGAGAAGCCTGCACGGGAGCTGAACGGCAGCGAGGCCGCCACCCCGCGGGACTCACCCCG
  CCCCGGGAAGCCAGACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGCCAAGAGCTGGCA
  GGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAGGGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGG
  GTGCCACGGGCACTGACCTGGACTTTGACTTATCCAGCGACAGCGAGAGCAGCAGTGAGTCCGAGGGCAC
  GAAGTCCTCCTCCTCCGCCTCTGATGGCGAAAGCGAGGGGAAAAGAGGCCGGCAGAAGCCGAAGGCTGCC
  CCAGAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGGCGGCCTGCAGCACCGAGTCTCC
  CCGGAGAGGCCGAGCCTGGCGCGCATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGCGA
  GCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGGAAGGAGGCGGAGACCGAGTCACAGAAC
  AGCGAGCTGTCGGGGGTCACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAGGAGGACA
  CGGATGAGGATGACCACCTCATCTACCTGGAGGAGATCCTGGTCCGTGTACACACTGACTACTATGCCAA
  GTATGACCGCTACCTCAACAAGGAGATCGAGGAGGCGCCGGACATCCGCAAGATCGTGCCGGAGCTCAAG
  AGCAAGGTGCTGGCAGACGTGGCCATAATTTTCAGTGGGCTACACCCGACAAACTTCCCGATAGAGAAGA
  CGCGGGAGCATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTGGTGCTGAGCCCCGACGC
  CCCTGACAGGGCCACGCACCTGATCGCCGCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGC
  GGACACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAGCGCTGGGACAAGGTGGAGGAGC
  AGCTCTTCCCGCTCAGGGACGATCACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGACCG
  GGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTTCTTCCCAAGGCCCAGCCTGGCCCCGAG
  GTTCGGATCTACGACTCCAACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCACCCTCCA
  GCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGGTGGACGACATCCTTGGAGAAGGCAGCGACGAC
  AGCGACAGCGAGAAGAGGAGGCCTGAGGAGCAGGAGGAGGAGCCCCAGCCCCGGAAGCCAGGGACCCGCA
  GGGAGCGGACGCTCGGGGCACCTGCGTCCAGCGAGAGGAGCGCGGCAGGGGGCCGGGGGCCCAGAGGCCA
  CAAGAGGAAGCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_048368 unedited
  GAGGAAAAAAAGGGAAAAAANNANNNNTTTTTAAAAAAAAATTAATACACCCGCCCGTTG
  NCGCAAAGGGCGGTAGGCGTGTACGGTGGGAAGTCTATATAAGCAGAGCTCATTTAGGTG
  ACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGCT
  GGGTTGTGTCGCCGCGGTAGGCGCTGCGCTCTGAGCGCAGCGCAGGCCCCGTACCGACCG
  CCCGCCCGCCCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCCGAGGGC
  GCCCCGACGGCGGCTGTGGCCGAGGTGCGCTGCCCGGGGCCCGCGCCGCTGCGCCTGCTG
  GAGTGGAGGGTGGCGGCGGGCGCGGCCGTGCGCATCGGCTCGGTGCTGGCCGTGTTCGAG
  GCCGCCGCCTCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAGCGCGCGGGCGTGGTGCGG
  GAGCTGTGCGCGCAGCCGGGCCAGGTGGTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAA
  GGATGCAGCCACCCGGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTCACC
  CAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCCACGGCGACCGTGTCCATG
  GTGCACAGCGTGCCCGGAGTTCGATGGTGAGCCTCCGAGCAAGCCTGAACAGCTGTGAAA
  AAGAAGACCAGCAGCGACTGCCACCGAACCCGGAAGCCTGTTGCTCATGGTGGACCTCGC
  ACCCATAACCTGAATCACACCACCCGAACACACCATGTCACCCCAAATGCCCAACTAAAC
  GCCTCCTTTCACTTTCCACCTGGCCCCGGCGCTGACACCCATGCCTTGACCACTCCTCCC
  TCTGTCTCACACTCGCCATGATCCCCTTCGCACAAATAAACTGCACAACTCTCCACAACT
  TGCAACCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_048368 unedited
  CACTACTAGTGTACCGCGGCCGCTATCTAGNGATCGGTTTTTTTTTTTTTTTTTTACAAA
  AGGATTTTTATTAAAGAGAAATCTGTTTGGTGGGTCAGATATGAAATAGATTTACAGAAA
  CTTTACATCAGGTGTCTCCAAGACATAAAAGGCCGCCCAGGAAAAGCAACGCCCCCTTGC
  CAGGATGCCAGTGGGAGGACGGCAGGATGGCAGCCCAGGCCACGTGGCGTGGACCCTGCG
  TAGGAGGCTGCAGGAAGCTCCAGGCTGCCCGACAGTCACGGCGTTCCCCGGAAATGGGTT
  CCCTAGGAGGGAGCAGCAGGCGGCGGGGGTTCCAGGCATGTCTGTGCTGGGCTCGGAGCT
  CGTGCACGCACACTGTCCTGCTTAAACTCCTAGTCCATGTCTCGTGGGACCCCCAAAGCC
  GTCCCCTAAGGAATGTGCTCTGGTACACAAGGGGAAAACACACCAACCCGCCCCTTACCG
  AGACAGCGGGCGCACCAGCCTGGGCCACGTGAGCCTCTGCTGAGCTCTTTGGCACAGCAC
  ACCTGGGCCTTTAACACCTGTCACTTACAAAAGTAGACATTCCTGTAGTAAAACTTCTTA
  AAAACACCTATTTCTGCAAAATAATGTGTTTCTGTATGTGGAGCTCTGCAAATATACATG
  TCCTTTGGGAAGAAAGCAGCGTGGACCGAGACTGAGGGCTGGTCCGGGGACNTCCNAATG
  CTGCTGGAAGTCGGTCAAGCTTCANTCCCTGCCCGCTGCCCGCGCTCACATGAAGGTCGT
  GAGCTCCGCCTCCAGCGCCCTGGCCATCTCGTCGGCCCTGGAGCTGCTGGCCCTCGTCCT
  CGTTGCTGGGACTCCTGGTGGACTCGCTGGCGGGCGTCCTCTTCTTTCAGCTACCCTTTG
  G
  
• Restriction Sites: NotI-NotI
• ACCN: NM_048368
• ORF Size: 2604 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_048368.2, NP_430255.2
• RefSeq Size: 3602
• RefSeq ORF: 2604
• Locus ID: 9150
• Domains: BRCT, CPDc
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Gene Summary: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  Transcript Variant: This variant (2) is missing a coding exon in the 3' region compared to variant 1. This results in a frame-shift and a shorter isoform (2, also known as FCP1b) with a distinct C-terminus (lacking the carboxy-terminal TFIIF-binding protein domain) compared to isoform 1.