UCP4 (SLC25A27) (NM_004277) Human Untagged Clone

CAT#: SC111116

SLC25A27 (untagged)-Human solute carrier family 25, member 27 (SLC25A27), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC25A27
• Synonyms: UCP4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111116 sequence for NM_004277 edited (data generated by NextGen Sequencing)
  ATGTCCGTCCCGGAGGAGGAGGAGAGGCTTTTGCCGCTGACCCAGAGATGGCCCCGAGCG
  AGCAAATTCCTACTGTCCGGCTGCGCGGCTACCGTGGCCGAGCTAGCAACCTTTCCCCTG
  GATCTCACAAAAACTCGACTCCAAATGCAAGGAGAAGCAGCTCTTGCTCGGTTGGGAGAC
  GGTGCAAGAGAATCTGCCCCCTATAGGGGAATGGTGCGCACAGCCCTAGGGATCATTGAA
  GAGGAAGGCTTTCTAAAGCTTTGGCAAGGAGTGACACCCGCCATTTACAGACACGTAGTG
  TATTCTGGAGGTCGAATGGTCACATATGAACATCTCCGAGAGGTTGTGTTTGGCAAAAGT
  GAAGATGAGCATTATCCCCTTTGGAAATCAGTCATTGGAGGGATGATGGCTGGTGTTATT
  GGCCAGTTTTTAGCCAATCCAACTGACCTAGTGAAGGTTCAGATGCAAATGGAAGGAAAA
  AGGAAACTGGAAGGAAAACCATTGCGATTTCGTGGTGTACATCATGCATTTGCAAAAATC
  TTAGCTGAAGGAGGAATACGAGGGCTTTGGGCAGGCTGGGTACCCAATATACAAAGAGCA
  GCACTGGTGAATATGGGAGATTTAACCACTTATGATACAGTGAAACACTACTTGGTATTG
  AATACACCACTTGAGGACAATATCATGACTCACGGTTTATCAAGTTTATGTTCTGGACTG
  GTAGCTTCTATTCTGGGAACACCAGCCGATGTCATCAAAAGCAGAATAATGAATCAACCA
  CGAGATAAACAAGGAAGGGGACTTTTGTATAAATCATCGACTGACTGCTTGATTCAGGCT
  GTTCAAGGTGAAGGATTCATGAGTCTATATAAAGGCTTTTTACCATCTTGGCTGAGAATG
  ACCCCTTGGTCAATGGTGTTCTGGCTTACTTATGAAAAAATCAGAGAGATGAGTGGAGTC
  AGTCCATTTTAA
  
  Clone variation with respect to NM_004277.4
  225 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004277 unedited
  TGTCCAGATTTTGTAATACGACTTACTTATAGGGCGGCCGCGATTCGGCACGAGGGGCAG
  CTGGACCACTCCAGCTGGGACTGCTAGGAAGGTTGCGGGTCCACCCGGCCGAGCCGAACG
  AGGGAAATGGTCCTCACCCGGCCACTCGCCGGTTGAAAAGGGGCCGCCCTGGCAGGGAAG
  CGGCCGCCGCGGCGCGGTGCAGCGCAGCGGCGAGAAGGAGTGCGTTATCGTCTTGCGCTA
  CTGCTGAATGTCCGTCCCGGAGGAGGAGGAGAGGCTTTTGCCGCTGACCCAGAGATGGCC
  CCGAGCGAGCAAATTCCTACTGTCCGGCTGCGCGGCTACCGTGGCCGAGCTAGCAACCTT
  TCCCCTGGATCTCACAAAAACTCGACTCCAAATGCAAGGAGAAGCAGCTCTTGCTCGGTT
  GGGAGACGGTGCAAGAGAATCTGCCCCCTATAGGGGAATGGTGCGCACAGCCCTAGGGAT
  CATTGAAGAGGAAGGCTTTCTAAAGCTTTGGCAAGGAGTGACACCCGCCATTTACAGACA
  CGTAGTGTATTCTGGAGGTCGAATGGTCACATATGAACATCTCCGAGAGGTTGTGTTTGG
  CAAAAGTGAAGATGAGCATTATCCCCTTTGGAAATCAGTCATTGGAGGGATGATGGCTGG
  TGTTATTGGCCAGTTTTTAGCCAATCCAACTGACCTAGTGAAGGTTCAGATGCCAATGGA
  AGGAAAAAGGAAACTGGNANGNAAACCATTGCGANTTCGTGGTGTACATCATGCATTTGC
  AAAAATCTTANNCTGAAGANGAATACNANGGNCTTTGGGCANGCTGGGTACCCATATACC
  AANACAGCACTGGTGAATATGGGAGATTAACCACTTATGATACAGTGAAACACTACTTGG
  TATTGNATACACCCACTTGANNGACATATCATGACTCACGGNTNATCAAGTTTATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004277
• ORF Size: 405 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004277.2, NP_004268.2
• RefSeq Size: 2006
• RefSeq ORF: 405
• Locus ID: 9481
• Domains: mito_carr
• Protein Families: Druggable Genome
• Gene Summary: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.