SIKE1 (NM_025073) Human Untagged Clone

CAT#: SC111370

SIKE1 (untagged)-Human suppressor of IKBKE 1 (SIKE1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIKE1
• Synonyms: SIKE
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_025073, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCTGCACCATCGAGAAGATCCTGACAGACGCCAAGACGCTGCTGGAGAGGCTACGGGAGCACGATG
  CGGCCGCCGAGTCGCTGGTGGATCAGTCGGCGGCGCTGCACCGGCGGGTAGCAGCTATGCGGGAGGCGGG
  GACAGCGCTTCCGGACCAGTATCAAGAGGATGCATCCGATATGAAGGACATGTCCAAATACAAACCTCAC
  ATTCTGCTGTCCCAAGAGAACACACAGATTAGAGACTTGCAACAGGAAAACAGAGAGCTATGGATTTCCT
  TGGAGGAACACCAGGATGCTTTGGAACTTATCATGAGCAAATATCGGAAACAGATGTTACAGTTAATGGT
  TGCTAAAAAAGCGGTGGATGCTGAACCAGTCCTGAAAGCTCACCAGTCTCACTCTGCAGAAATTGAGAGT
  CAGATTGACAGAATCTGTGAAATGGGAGAAGTGATGAGGAAAGCAGTTCAGGTGGATGATGACCAGTTTT
  GTAAGATTCAGGAAAAATTAGCCCAATTAGAGCTTGAAAATAAGGAACTTCGAGAATTATTGTCCATCAG
  CAGTGAGTCTCTTCAAGCCAGAAAGGAAAACTCAATGGACACTGCTTCCCAAGCCATCAAATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_025073 unedited
  CAGGTTTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGGCAGGGGCTGG
  GGTGGTGCTGCTGCTATGAGCTGCACCATCGAGAAGATCCTGACAGACGCCAAGACGCTG
  CTGGAGAGGCTACGGGAGCACGATGCGGCCGCCGAGTCGCTGGTGGATCAGTCGGCGGCG
  CTGCACCGGCGGGTAGCAGCTATGCGGGAGGCGGGGACAGCGCTTCCGGACCAGTATCAA
  GAGGATGCATCCGATATGAAGGACATGTCCAAATACAAACCTCACATTCTGCTGTCCCAA
  GAGAACACACAGATTAGAGACTTGCAACAGGAAAACAGAGAGCTATGGATTTCCTTGGAG
  GAACACCAGGATGCTTTGGAACTTATCATGAGCAAATATCGGAAACAGATGTTACAGTTA
  ATGGTTGCTAAAAAAGCGGTGGATGCTGAACCAGTCCTGAAAGCTCACCAGTCTCACTCT
  GCAGAAATTGAGAGTCAGATTGACAGAATCTGTGAAATGGGAGAAGTGATGAGGAAAGCA
  GTTCAGGTGGATGATGACCAGTTTTGTAAGATTCAGGAAAAATTAGCCCAATTAGAGCTT
  GAAAATAAGGAACTTCGAGAATTATTGTCCATCAGCAGTGAGTCTCTTCAAGCCAGAAAG
  GAAAACTCAATGGACACTGCTTCCCAAGCCATCAAATAACTGAACTCTNGATGATGGCTG
  GNAGATGTCTATCAAGGAAGGAGTTACTGTCTTCCCATTCAGTACTGTCCATTAGTGTNC
  TGGCTCAGATTGATTTATCTTAATAAAGTATCAGGTGGNCATTANAATCCAGTCATATTG
  GCTGCCCACAGTCTCAGAGTGGTAATGGGATACTACATGCTGATTCACCATTCTTTTCAA
  GAGACTACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_025073
• ORF Size: 624 bp
• Insert Size: 5850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_025073.1, NP_079349.1
• RefSeq Size: 2209
• RefSeq ORF: 624
• Locus ID: 80143
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, which results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.