ZNF420 (NM_144689) Human Untagged Clone

CAT#: SC111530

ZNF420 (untagged)-Human zinc finger protein 420 (ZNF420)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZNF420
• Synonyms: APAK
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_144689, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGG
  ACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGACTT
  GCCTTCAAGGTGTGCAAGTAAGGACTTATCTCCAGAAAAGAACACTTATGAAACAGAATTATCCCAATGG
  GAAATGAGTGACAGACTTGAAAACTGTGATCTTGAAGAGTCCAATTCCAGGGATTATTTGGAAGCCAAAG
  GCAAGATGGAGAAGCAACAAGAAAATCAGAAGGAATATTTCAGGCAAGGGATGATCATATATGACAAAAT
  GTCCATTTTCAACCAGCATACTTACTTATCTCAACATTCAAGATGTCATTCTACTGAGAAACCCTATAAA
  TGTAAGGAATGTGGGAAAGCCTTCAGACGAGCCTCACACCTAACACAACATCAAAGTATTCATACTGGTG
  AAAAACCCTATGAATGTAAGCAATGCGGGAAGGCCTTTAGTCGTGATTCACAACTCAGTCTTCATCAGAG
  ACTTCATACTGGTGAGAAACCCTATGCATGTAAGGAATGTGGGAAGGCCTTTACTCAAAGCTCACAACTT
  ATTTTACATCATAGAATTCATACTGGTGAAAAACCATATAAATGTGAAGAATGTGGGAAAGCCTTTATTC
  GTAGCTCACAACTTACCCGACATCAAAAAGTTCATACTGGTGAGAAACCTTATGAATGTAAAGAATGTGG
  GAAGGCCTTTACTCAGAATTCACAACTTACACTACACCAGAGACTTCATACTGGTGAAAAGCTCTATGAA
  TGTAAAGAATGTAGGAAGGTCTTTACTCAGCTCTCACAACTTATTCTGCATAAGAGAATTCATACCGGTG
  AGAAACCCTATGAATGTAAGGAATGTGGAAAAGCTTTTATTTGTGGCTCACAGCTTTCTCAACATCAGAA
  AATTCATAATGGGGAAAAACCATATGAATGTAAGGAATGTGGAAGGGCCTTTATTCGGGGCTCACTACTG
  ATGCAACATCAGAGGATTCATACTGGTGAAAAACCCTATAAATGTGAAGAATGTGGGAAGGCCTTTATCC
  GTGGCTCACAACTTACTCAACACCAGAGAATTCACACCAATGAAAAGCCCTATGAATGTAAGGAATGTGG
  AAAGATGTTTAGTCATGGCTCACAACTTACTCAACATCAGAGAATACACACTGGTGAGAAACCCTATCAA
  TGTAAGGAATGTGGAAAAGCGTTTAATCGTGGCTCACTCCTTACACGACACCAGAGGATTCATACTGGTG
  AGAAACCCTATGAATGTAAAGAATGTGGAAAAACCTTTAGTCGTGGCTCAGAACTTACTCAACATGAGCG
  AATTCACACAGGTGAGAAACCCTATGAATGTAAGGAATGTGGGAAATCTTTTATTCGTGGTTCCCAGCTT
  ACTCAACATCAGAGAATCCATACTGGTGAGAAACCTTATGAATGTAAAGAATGTAGAATGGCCTTTACTC
  AGAGTTCACATCTTTCCCAACATCAAAGACTTCACACTGGTGAGAAACCCTATGTGTGTAATGAATGTGG
  AAAGGCCTTTGCGCGTGGCTTACTACTTATACAACATCAGAGAATTCATACTGGTGAGAAACCATATCAA
  TGTAAGGAATGTGGGAAAGCCTTTATTCGTGGTTCACAGTTGACTCAACATCAGCGAATTCACACTGGAG
  AAAAACCCTATGAATGCAAGGAGTGTGGCAAGGCCTTTAGTCATGGCTCTCAGCTTACTCTACATCAGAG
  AATCCATACTGGTGAGAAGCCCTATGAATGCAGAGAATGTAGAAAGGCCTTTACTCAGAGTTCACATCTT
  TCTCGGCATCAGAGAATTCATACTGGTGAGAAACCATATCAATGTAAGGAATGTGGGAAGGCCTTTACTC
  GTGGTTCACAGCTAACTCAACATCAGAGAATTCATATCAGTGAGAAATCTTTTGAATATAAGGAATGTGG
  GATTGACTTTAGTCATGGCTCACAAGTTTACATGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144689 unedited
  CGGCCGCGAAATTCGCACGAGGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAATTG
  GGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGCTCTGCAT
  TCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCA
  GCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCT
  CAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTG
  GAGAACTATAGCAACTTGGTATCACTAGACTTGCCTTCAAGGTGTGCAAGTAAGGACTTA
  TCTCCAGAAAAGAACACTTATGAAACAGAATTATCCCAATGGGAAATGAGTGACAGACTT
  GAAAACTGTGATCTTGAAGAGTCCAATTCCAGGGATTATTTGGAAGCCAAAGGCAAGATG
  GAGAAGCAACAAGAAAATCAGAAGGAATATTTCAGGCAAGGGATGATCATATATGACAAA
  ATGTCCATTTTCAACCAGCATACTTACTTATCTCAACATTCAAGATGTCATTCTACTGAG
  AAACCCTATAATGTAGGGAATGTGGGAAAGCCTTCAGACGAGCCTCACACCTAACACAAC
  ATCAAAGTATTCATACTGGTGAAAAACCCTATGAATGTAAGCATGCGGGAAGGCCTTTAG
  TCGTGATACANAACTCAGTCTCATCAAAACTCATACTGGTGAGAACCTNTGCATGTAAGG
  ATGGGGGGGAGGGCCTTACTCAAAGCTACACTTATTTTACTCATAGAATNCTACTGGGGG
  AAAACTTATAATGTGAAGAATGGGGGGAAAGCCTTTTTTCGTAGCTACAACTACCGCTTT
  CAAAGTCTTCCGGGGGAGAACCTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_144689 unedited
  ACTATGAACCGCGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTGCA
  TCAACAAATAAGATGTTTAATTTTATTTAAAGAGAAACAGGAGGCAAGCAGACCAGAGCT
  AGTATGGCTGTTCCACAAAGTCATCAGGGTTGCAGACTCCTTCTGTATTTCTGCTCCATG
  ATCCATAACACCCAGATACCATTCTCAAAGTCCCCATGAGAGTAACGGAGCTCCAGCTTA
  GATGTCCACATTGTAGGCACGGAAAAAAAGACAGGAAAAATGGATTTCGTAAATCTCCTA
  CTCATATAAATATCACTTCTATCTTGTTGACCTGCAAGGAAGGCTGAGATTTTCAGCCCA
  GAAATTTGTTACTAAAAAAGAGAAAATAGATATAGGGTAGGAAAAAAGCAGTCTGTATCA
  CAAACTCTCATCATTTTTCATTGCAAAATAGTCTGTAATATCAGTTATTTTGTTTACTTC
  AAAAGCAATACATTCAAGTTTTTAAAAAATTCCTAGATTTATTAGACTTTGGATCTTAGA
  CTTCGTTAAAAATCACTTCACACCTTGTCCCACTTCTCTAACAGCTGTGCTCAATAATAC
  ACTGATTACATCCACTGGGTTTTTTTTTTTTTAATAATACACTGATTATATCCACTGGGT
  TTTTTTTTTTTTTACAGTATGAATTTTCCTCTTATAGCATAATGGATGAGATTTAAATGA
  CAGCTTTCTCACATTCATTATTGCATACAGTGCCCCCCCAACAAGTCATCTTGGATGTGT
  TGTAAAAGATTTCTCAATATTCAATATACTATAAAGTCTCCTCCCTCATGCAAATCTCTA
  AAAAACCCTGTGAAAATGGGGCTAAATTTGTGGATGCTCGTTCAGGCCCATTCAAGACTT
  TACTGGAAAACTCATAAAACTTCAGAACTACATAAGTAATACTTAGTCTTCTAAAAGATA
  A
  
• Restriction Sites: NotI-NotI
• ACCN: NM_144689
• ORF Size: 2067 bp
• Insert Size: 4700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_144689.3, NP_653290.2
• RefSeq Size: 2990
• RefSeq ORF: 2067
• Locus ID: 147923
• Domains: KRAB, zf-C2H2
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]