CDC25A (NM_201567) Human Untagged Clone

CAT#: SC111607

CDC25A (untagged)-Human cell division cycle 25 homolog A (S. pombe) (CDC25A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC25A
• Synonyms: CDC25A2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_201567, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAACTGGGCCCGGAGCCCCCGCACCGCCGCCGCCTGCTCTTCGCCTGCAGCCCCCCTCCCGCGTCGC
  AGCCCGTCGTGAAGGCGCTATTTGGCGCTTCAGCCGCCGGGGGACTGTCGCCTGTCACCAACCTGACCGT
  CACTATGGACCAGCTGCAGGGTCTGGGCAGTGATTATGAGCAACCACTGGAGGTGAAGAACAACAGTAAT
  CTGCAGAGAATGGGCTCCTCCGAGTCAACAGATTCAGGTTTCTGTCTAGATTCTCCTGGGCCATTGGACA
  GTAAAGAAAACCTTGAAAATCCTATGAGAAGAATACATTCCCTACCTCAGAAGCTGTTGGGATGTAGTCC
  AGCTCTGAAGAGGAGCCATTCTGATTCTCTTGACCATGACATCTTTCAGCTCATCGACCCAGATGAGAAC
  AAGGAAAATCTTTCCTCAAATGAAAGAGATAGCAGTGAACCAGGGAATTTCATTCCTCTTTTTACACCCC
  AGTCACCTGTGACAGCCACTTTGTCTGATGAGGATGATGGCTTCGTGGACCTTCTCGATGGAGAGAATCT
  GAAGAATGAGGAGGAGACCCCCTCGTGCATGGCAAGCCTCTGGACAGCTCCTCTCGTCATGAGAACTACA
  AACCTTGACAACCGATGCAAGCTGTTTGACTCCCCTTCCCTGTGTAGCTCCAGCACTCGGTCAGTGTTGA
  AGAGACCAGAACGATCTCAAGAGGAGTCTCCACCTGGAAGTACAAAGAGGAGGAAGAGCATGTCTGGGGC
  CAGCCCCAAAGAGTCAACTAATCCAGAGAAGGCCCATGAGACTCTTCATCAGTCTTTATCCCTGGCATCT
  TCCCCCAAAGGAACCATTGAGAACATTTTGGACAATGACCCAAGGGACCTTATAGGAGACTTCTCCAAGG
  GTTATCTCTTTCATACAGTTGCTGGGAAACATCAGGATTTAAAATACATCTCTCCAGAAATTATGGCATC
  TGTTTTGAATGGCAAGTTTGCCAACCTCATTAAAGAGTTTGTTATCATCGACTGTCGATACCCATATGAA
  TACGAGGGAGGCCACATCAAGGGTGCAGTGAACTTGCACATGGAAGAAGAGGTTGAAGACTTCTTATTGA
  AGAAGCCCATTGTACCTACTGATGGCAAGCGTGTCATTGTTGTGTTTCACTGCGAGTTTTCTTCTGAGAG
  AGGTCCCCGCATGTGCCGGTATGTGAGAGAGAGAGATCGCCTGGGTAATGAATACCCCAAACTCCACTAC
  CCTGAGCTGTATGTCCTGAAGGGGGGATACAAGGAGTTCTTTATGAAATGCCAGTCTTACTGTGAGCCCC
  CTAGCTACCGGCCCATGCACCACGAGGACTTTAAAGAAGACCTGAAGAAGTTCCGCACCAAGAGCCGGAC
  CTGGGCAGGGGAGAAGAGCAAGAGGGAGATGTACAGTCGTCTGAAGAAGCTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_201567 unedited
  ACTTATAGGCGGCCCGCGAATTCGGCACGAAGGCTCTGCGAGGCCGGGCGCCGCCATGNA
  ACTGGGCCCGGAGCCCCCGCACCGCCGCCGCCTGCTCTTCGCCTGCAGCCCCCCTCCCGC
  GTCGCAGCCCGTCGTGAAGGCGCTATTTGGCGCTTCAGCCGCCGGGGGACTGTCGCCTGT
  CACCAACCTGACCGTCACTATGGACCAGCTGCAGGGTCTGGGCAGTGATTATGAGCAACC
  ACTGGAGGTGAAGAACAACAGTAATCTGCAGAGAATGGGCTCCTCCGAGTCAACAGATTC
  AGTTTCTGTCTAGATTCTCCTGGGCCATTGGACAGTAAAGAAAACCTTGAAAATCCTATG
  AGAAGAATACATTCCCTACCTTAAGCTGTTGGGGAATGTAGTCCAGCTCTGAAGAGGAGC
  CATTCTGATTCTCTTGACCATGACATCTTTCAGCTCATCGACCCAGATGAGAACAAGGAA
  AATCTTTCCTCAAATGAAAAGAATAGCAGTGACCAGGGAATTTCATTCCTCTTTTTACAC
  CCCAGTCACCTGTGACGNCACTTTGTCTGAGGAGGATGATGGGTTTCGTGGACCTTCTCG
  ATGGAGAGATCTGAGATGGAGGGGGAGACCCCTCGTGCTGGAAGCCTCTGACAGTCCTCT
  CGTATGAGACTACAACCTTGCACCGGCAAAGCGTGTTGATCCTCCCCTGTGACTCCACCC
  GGCCAGGGTGGGGAGAACCNAACGACTCAAGAGGGTCCCCGGGAATAAAGGAGGAAAAAT
  ATTGTGGGGGGCACCCCAGAGCACTATCCNAAAGGCCAGAACTTTCTTAANCTTATCTGC
  TCTCCCAAGCCCTTGGAAAATTGGCAGACAGCCTTTAGGATTCTCCAGGTATCTTTAAAG
  GGGGAAAAAGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_201567 unedited
  AGCTTTGGACCCGCGGCCGCAATCTAGAAGTCGGTTTTTTTTTTTTTTTTTTTTGGGTTC
  AAGATCTTTTATTTTCAGAGCTTCCAACAGTTGGTTAGTAATGCTAGCTAAGCTGGTATA
  ATCTGAAGGCCATCCCACCTTTCTCTTTAGGCAGTCAACCAACAGAATCTCTTTCTTACA
  AACAATATCATTAACCAGTTGGAATCTGTCTCAATGCGCGTGTAGGAAGAAGTCCTCTCC
  CCCACATTTTTCCCAACAAGATTGTTTTATAGCCAAATGTAACTCAAACCCGTAACACAG
  CAACTAGCCATCTCCAGTATCACTGATTCCCACCCCAAGAAGTTGAGGTAAGAGGGGAGA
  GACTGTCTCCTGTTTAAGAAAAACCCACCTACACCTCAGTGAAGCCGTGATGGTAAGGAG
  GCTGGCACCAGAGGGCAGGGATGAGTAGGCACTGAAACAGGGCTCTCTAGAATCAATGAA
  GGCTGCCCCAGCTCCTTGGATGAGGTGGNAGTCTGAAACTCCCAGCCCCCTGGGCTCGCT
  AGCGCGGACGCCCGCGCCCNNCCCACACCCATTGGGTTTCCCCGCCACCCCCCGACCCAG
  GGGNAAGCGCGCACCGTGACACCGCCGCGCCCCTACCTCTCGCAGAGCACGGCCGGCCAG
  AGTCGGGCCGAGGGGCGNNACCCCAGCTACGGTGCCGCCAATGCCCACGGTCTCCGACCC
  CCCCTCCCCCCCCGCCNCGTCTGCACCCCCGCGCCCCGCCGTCGATGTGCCCGTTGGCGG
  ACCGCCGCCGCCCGCTCGGNACACCGCCCACCCGCGCCGCGACGCGATTCCACGAGGGCG
  GCGAGGCCGCCCGTCGCCGCAATGCCCGCGGAGCCACGCGGCCGACGTACGCTCCGCTAT
  AGCGGGTTGACACAGTCACCGCGCGCCCAGCGTCTNCAGACGAGTCGAGAGGGGCGAGCC
  TCATGCCGACGCAGCNGACGCGCAGAGGCGCAGTGAGCCGACACACGCGGACACGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_201567
• ORF Size: 1455 bp
• Insert Size: 3220
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_201567.1, NP_963861.1
• RefSeq Size: 3597
• RefSeq ORF: 1455
• Locus ID: 993
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Cell cycle, Progesterone-mediated oocyte maturation
• Gene Summary: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.