EXOC2 (NM_018303) Human Untagged Clone

CAT#: SC111916

EXOC2 (untagged)-Human exocyst complex component 2 (EXOC2)


  "NM_018303" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol EXOC2
Synonyms SEC5; SEC5L1; Sec5p
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC111916 sequence for NM_018303 edited (data generated by NextGen Sequencing)
ATGTCTCGATCACGACAACCCCCCCTTGTGACCGGCATCTCTCCAAATGAAGGGATACCA
TGGACGAAGGTCACAATCAGGGGAGAAAATCTGGGGACTGGCCCCACCGACCTCATAGGC
TTGACCATTTGTGGACATAATTGCCTCCTGACGGCAGAATGGATGTCTGCAAGTAAAATA
GTATGTCGAGTGGGACAAGCCAAAAATGACAAAGGAGACATTATTGTCACCACTAAGTCA
GGTGGCAGAGGAACCTCAACAGTCTCTTTCAAGCTACTCAAACCTGAGAAAATAGGCATT
TTGGATCAGTCTGCTGTGTGGGTTGATGAAATGAATTATTATGATATGCGCACTGACAGG
AACAAAGGAATTCCGCCCTTGTCCTTACGTCCTGCTAACCCGCTTGGCATTGAGATTGAA
AAAAGTAAATTTTCGCAGAAGGACTTAGAAATGCTATTCCATGGAATGAGTGCTGATTTT
ACAAGTGAGAATTTCTCAGCAGCCTGGTATCTTATAGAGAATCACTCAAACACCAGTTTT
GAGCAGCTCAAAATGGCAGTCACCAACCTAAAGAGACAGGCTAACAAGAAGAGTGAGGGC
AGCCTGGCCTATGTGAAAGGCGGTCTCAGTACATTCTTCGAAGCACAGGATGCCCTCTCA
GCCATCCATCAAAAACTAGAAGCAGATGGAACGGAAAAAGTAGAAGGATCCATGACGCAG
AAACTGGAGAATGTTCTGAACAGAGCAAGTAATACTGCAGACACATTGTTTCAAGAAGTA
TTAGGTCGGAAAGACAAGGCAGATTCCACTAGAAATGCACTCAATGTGCTTCAGCGATTT
AAGTTTCTTTTCAACCTTCCTCTAAATATTGAAAGGAATATTCAAAAGGGTGATTATGAT
GTGGTTATTAATGATTATGAAAAGGCCAAGTCACTTTTTGGGAAAACGGAGGTGCAAGTT
TTCAAGAAATATTATGCTGAAGTAGAAACAAGGATTGAAGCTTTAAGAGAATTACTTCTG
GATAAATTGCTTGAGACACCATCAACTTTACATGACCAAAAACGTTACATAAGGTACCTG
TCTGACCTTCATGCGTCTGGTGACCCTGCTTGGCAATGCATTGGAGCCCAACACAAGTGG
ATCCTTCAGCTCATGCACAGTTGCAAAGAGGGCTACGTGAAAGATCTGAAAGGTAACCCA
GGCCTGCACAGTCCCATGTTGGATCTTGATAATGATACACGTCCCTCAGTGTTGGGCCAT
CTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCTGGTCGAGACGACACG
TGGAGATACAAAACTCCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTG
AGCCAGCTGCCTAACTTCTGGAAACTCTGGATCTCCTACGTTAATGGAAGCCTCTTCAGT
GAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTAAGGCAAAGACAAAAT
GATTTTAAGAAAATGATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCC
CTGCTTCCCCTCAGCATCCGGGATGGGGAAGCCAAGCAGTACGGAGGCTGGGAGGTGAAG
TGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTAAGACTTACTCACGAA
TCGTTGACTGCCCTTGAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTG
GATCTCCGAGTACGTTGCGTAATGGCCACGTTGCAGCACACGGCGGAAGAAATAAAGAGA
TTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACTTCTCTACCATGTCAG
TTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCG
GGAGAGGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATC
AATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAGAT
ATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCAT
GAAGACTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTAT
CTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGGGA
ATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTT
GAAAATTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTAT
GCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAAAA
GAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTG
GTCCCTCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATG
CAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTGCT
TTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCT
TTGGAAGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTG
AACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAACC
ATGATGAAAACATAA

Clone variation with respect to NM_018303.4
1677 t=>c
>OriGene 5' read for NM_018303 unedited
GATTATGTATCCGACTTACTATAGGGNNCGGCCGCGCAATTCGGCACGAGGGCGAGACCT
ACCGGGCCCTGTCTGTGCCGGCCGTGAGCTGCGGCAGGACGGCTGGAGATTACTTCTCTA
ACAGGATCACCAGTTTGCTCCACAAAGCACAATGTCTCGATCACGACAACCCCCCCTTGT
GACCGGCATCTCTCCAAATGAAGGGATACCATGGACGAAGGTCACAATCAGGGGAGAAAA
TCTGGGGACTGGCCCCACCGACCTCATAGGCTTGACCATTTGTGGACATAATTGCCTCCT
GACGGCAGAATGGATGTCTGCAAGTAAAATAGTATGTCGAGTGGGACAAGCCAAAAATGA
CAAAGGAGACATTATTGTCACCACTAAGTCAGGTGGCAGAGGAACCTCAACAGTCTCTTT
CAAGCTACTCAAACCTGAGAAAATAGGCATTTTGGATCAGTCTGCTGTGTGGGTTGATGA
AATGAATTATTATGATATGCGCACTGACAGGAACAAAGGAATTCCGCCCTTGTCCTTACG
TCCTGCTAACCCGCTTGGCATTGAGATTGAAAAAAGTAAATTTTCGCAGAAGGACTTAGA
AATGCTATTCCATGGAATGAGTGCTGATTTTACAAGTGAGAATTTCTCAGCAGCCTGGTA
TCTTATAGAGAATCACTCAAACACCAGTTNTGAGCAGCTCAAAATGGCAGTCACCAACCT
AAAGAGACAGGCTAACAAGAAGAGTGAGGGCAGCCCTGCCTATGTGAAAGGCGGTCTCAG
TACATTCTTCGAAGCACANGATGCCCTCTCAGCCATCCATCANANACTAGAAGCAGATGG
AACGGNAAAAGTAGNAAGATCCATGACGCAGAAACTGGAGAATGTTCTGAACAGAGCAGT
NATACTGCAGAACATTGNTTNCAGAAGTATTTAGTCGAAGACAGGCAGATNCACTAGAAT
GCACTCATGTGCTCAGCGATTTAGCTTCTTTCAACCTTCTCTAATATTGAAGGAT
>OriGene 3' read for NM_018303 unedited
TATGGACCGGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTAAAGGCAGATTCTTTATTGGCTGAATGGGCTGTAGTAGATATTT
AAAATATCACAAACATTCATGATTGCAGTTTTTAAACTTAGCTCACAGTTGAGTTAGATA
CCACAGTTAACATACTTAGGAAAGACAATTCTTAACAGCTTTATCAAGCACATTTGGGAA
AGATTAAACTTTCATTTCCAGTTACCATGATGTCCCCCCATACCCCAAATGAACCAACCC
ATTTTTTTATTTTAAATAATGGAAACTGTACATGGCTACCCTGGGCTCTAAAATTACTTG
CATTAATGAGGACATTAATTTTAGCATTTAAAAAAAGAGATTTAAAAATAACCCTAGAAA
AACTTGAAAACCCTGACAAGCCGACTACAAAGAGAATTCCTCTCTGAAAATTTTCAAATG
CCACGGTATGAGGGAGTTGGGTGGGCTGCTGACTCTGAAAGAAGTCCCGGGGACCTGAAC
CTATTCCAGTGAAGCCAGTCAGCAGTGAATGTGGGGCAAGTGCATGCGGCTGGTCTACAG
CTCCCATTGCCTGGTGACCAAGGAGCATCCTGAAGTTTCAAAGAAAAAACTGTGTGACAG
CAGCATTGTTCCAGCTACTGAGCAAGATCCTTCAGCAGGTAAGAAGTGGCAGAGACAGTC
ACCTGCTGAAGGAGCGGGCAGGGAGTTGGCCGTCCCGCGGAGCCTGGCCTTTCCGTTAGG
GGACCCTGAAGTCTGCGACCGCCCCGNCAACACCTGANAGTGTGACACAGTGCCCGTTAC
CATTCACACTCCATCCAGATAACACACAGGCCCTCAGAACTGCACACGTGCATGTGTTGT
GCGCCCGACAATTAGAGTGAGGGAGATGGAAGCTATGCCTTAACCTGTGAAAATAAAATC
AGTAGCAAACGCAAGTT
Restriction Sites NotI-NotI     
ACCN NM_018303
ORF Size 2775 bp
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_018303.4, NP_060773.3
RefSeq Size 4458
RefSeq ORF 2775
Locus ID 55770
Domains IPT
Gene Summary The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Transcript Variant: This variant (1) represents the shorter, protein coding transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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