KEAP1 (NM_012289) Human Untagged Clone

CAT#: SC111946

KEAP1 (untagged)-Human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KEAP1
• Synonyms: INrf2; KLHL19
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012289, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGCCAGATCCCAGGCCTAGCGGGGCTGGGGCCTGCTGCCGATTCCTGCCCCTGCAGTCACAGTGCC
  CTGAGGGGGCAGGGGACGCGGTGATGTACGCCTCCACTGAGTGCAAGGCGGAGGTGACGCCCTCCCAGCA
  TGGCAACCGCACCTTCAGCTACACCCTGGAGGATCATACCAAGCAGGCCTTTGGCATCATGAACGAGCTG
  CGGCTCAGCCAGCAGCTGTGTGACGTCACACTGCAGGTCAAGTACCAGGATGCACCGGCCGCCCAGTTCA
  TGGCCCACAAGGTGGTGCTGGCCTCATCCAGCCCTGTCTTCAAGGCCATGTTCACCAACGGGCTGCGGGA
  GCAGGGCATGGAGGTGGTGTCCATTGAGGGTATCCACCCCAAGGTCATGGAGCGCCTCATTGAATTCGCC
  TACACGGCCTCCATCTCCATGGGCGAGAAGTGTGTCCTCCACGTCATGAACGGTGCTGTCATGTACCAGA
  TCGACAGCGTTGTCCGTGCCTGCAGTGACTTCCTGGTGCAGCAGCTGGACCCCAGCAATGCCATCGGCAT
  CGCCAACTTCGCTGAGCAGATTGGCTGTGTGGAGTTGCACCAGCGTGCCCGGGAGTACATCTACATGCAT
  TTTGGGGAGGTGGCCAAGCAAGAGGAGTTCTTCAACCTGTCCCACTGCCAACTGGTGACCCTCATCAGCC
  GGGACGACCTGAACGTGCGCTGCGAGTCCGAGGTCTTCCACGCCTGCATCAACTGGGTCAAGTACGACTG
  CGAACAGCGACGGTTCTACGTCCAGGCGCTGCTGCGGGCCGTGCGCTGCCACTCGTTGACGCCGAACTTC
  CTGCAGATGCAGCTGCAGAAGTGCGAGATCCTGCAGTCCGACTCCCGCTGCAAGGACTACCTGGTCAAGA
  TCTTCGAGGAGCTCACCCTGCACAAGCCCACGCAGGTGATGCCCTGCCGGGCGCCCAAGGTGGGCCGCCT
  GATCTACACCGCGGGCGGCTACTTCCGACAGTCGCTCAGCTACCTGGAGGCTTACAACCCCAGTGACGGC
  ACCTGGCTCCGGTTGGCGGACCTGCAGGTGCCGCGGAGCGGCCTGGCCGGCTGCGTGGTGGGCGGGCTGT
  TGTACGCCGTGGGCGGCAGGAACAACTCGCCCGACGGCAACACCGACTCCAGCGCCCTGGACTGTTACAA
  CCCCATGACCAATCAGTGGTCGCCCTGCGCCCCCATGAGCGTGCCCCGTAACCGCATCGGGGTGGGGGTC
  ATCGATGGCCACATCTATGCCGTCGGCGGCTCCCACGGCTGCATCCACCACAACAGTGTGGAGAGGTATG
  AGCCAGAGCGGGATGAGTGGCACTTGGTGGCCCCAATGCTGACACGAAGGATCGGGGTGGGCGTGGCTGT
  CCTCAATCGTCTCCTTTATGCCGTGGGGGGCTTTGACGGGACAAACCGCCTTAATTCAGCTGAGTGTTAC
  TACCCAGAGAGGAACGAGTGGCGAATGATCACAGCAATGAACACCATCCGAAGCGGGGCAGGCGTCTGCG
  TCCTGCACAACTGTATCTATGCTGCTGGGGGCTATGATGGTCAGGACCAGCTGAACAGCGTGGAGCGCTA
  CGATGTGGAAACAGAGACGTGGACTTTCGTAGCCCCCATGAAGCACCGGCGAAGTGCCCTGGGGATCACT
  GTCCACCAGGGGAGAATCTACGTCCTTGGAGGCTATGATGGTCACACGTTCCTGGACAGTGTGGAGTGTT
  ACGACCCAGATACAGACACCTGGAGCGAGGTGACCCGAATGACATCGGGCCGGAGTGGGGTGGGCGTGGC
  TGTCACCATGGAGCCCTGCCGGAAGCAGATTGACCAGCAGAACTGTACCTGTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012289 unedited
  TCACTATATTTGTATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGGAGCGC
  GGCCATGGCGGGGTCCCTGAGTGCCAGAGGTGGTGGTGTTGCTTATCTTCTGGAACCCCA
  TGCAGCCAGATCCCAGGCCTAGCGGGGCTGGGGCCTGCTGCCGATTCCTGCCCCTGCAGT
  CACAGTGCCCTGAGGGGGCAGGGGACGCGGTGATGTACGCCTCCACTGAGTGCAAGGCGG
  AGGTGACGCCCTCCCAGCATGGCAACCGCACCTTCAGCTACACCCTGGAGGATCATACCA
  AGCAGGCCTTTGGCATCATGAACGAGCTGCGGCTCAGCCAGCAGCTGTGTGACGTCACAC
  TGCAGGTCAAGTACCAGGATGCACCGGCCGCCCAGTTCATGGCCCACAAGGTGGTGCTGG
  CCTCATCCAGCCCTGTCTTCAAGGCCATGTTCACCAACGGGCTGCGGGAGCAGGGCATGG
  AGGTGGTGTCCATTGAGGGTATCCACCCCAAGGTCATGGAGCGCCTCATTGAATTCGCCT
  ACACGGCCTCCATCTCCATGGGCGAGAAGTGTGTCCTCCACGTCATGAACGGTGCTGTCA
  TGTACCAGATCGACAGCGTTGTCCGTGCCTGCAGTGACTTCCTGGTGCAGCAGCTGGACC
  CCAGCAATGCCATCGGCATCGCCCACTTCGCTGAGCAGATTGGCTGTGTGGAGTTGCACC
  ACCGTGCCCGGGGAGTACATCTACATGCATTTTGGGGAGGTTGGCCAACCAAGAGGAGTT
  CTTCACCCTGTCCCACTGGCCACTGGGTGACCCTCATCAGCCGGGACGACCTGNACGTGC
  GCTGCGAGTCCCAAGTCTTCCACGCCCTGCATCAACTGGGTGCAAGNACGACTGCGAACA
  GCGACCGTTTTACNTTCAGGCGCTTGCTGCGGGCCCGGCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012289 unedited
  GCACGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAT
  TAGTCTGTTCTTTATTTTCCTTGGAAAATTACAGGGTTACTTATCAACAAAATAACTGTC
  CCTCCGGGGGGGAAGTGCCATCCGGTGGCTTCTATGTACAGGCCCATCCCTGGGAACCAC
  ATTTCCAAAGAGGGGCCTCCCCCTGAGGCCCCCATTGGCCCCCTCCCAGGTATCCAAGAA
  TAAATCACATGGTGACAGCTGCCGGCATGGGTGAGTGGGACCCAAGCCTATTACCCGGCC
  AGAGGGTTTGGGGGCCTCTCTCCTGGAAGCCTGCTCTTTCCACACCCCCTTTCCCAGCCA
  GGCTGTCTTGGACACTCCCGGGGCTCCGCTGAGGGGCACATGATTCCCGCTTTGGACTTC
  TTTTGAGATGTCATTTTAACACTGAGGCATCCTGGCCTCCCTTCCCGGAAAATGGGTTAT
  TTGCAGAGCTGGCTTTTCTTTTAATCCCGGTTTTTGTACAAAAACAATGATACTCCCCAT
  TGGACTGTATTTTTGCCCAAAAAACAAAAGTGCCTCAACAGGTACAGTTCTGCTGGGCAA
  TCTGCTTCCCGGAGGGCTCCATGGTGACAGCCACCCCCACCCCACTCCCGCCCCGATGGC
  TTTCCGGTCACCTCGCCCCAAGTGGCTTGATTCTGGGCCGAACCCTCCACACTGGTCCGG
  AACCTGTGACCCTCTTAGCCCCAAGGCCTAAATTCTCCCCTGGGGCCAAGGATCCCCAGG
  CCCTTTCCGGGCCTTTGGGGCCTCCAAACTCCCGTCTCTTTTCACCACAAACGCCCCCCC
  TGTCACCGGGCCCGCCCCCATCCCCCCCCCCTAATACCCCCGGACAGACCAAACCCCTCC
  CCTTCCGGAGGGCCCCTGCTCTACCCCCGCACCCCCCCTTTGGGGTAGAACCCCACGAAT
  ACGCCGTCGCCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012289
• ORF Size: 1875 bp
• Insert Size: 2600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012289.3, NP_036421.2
• RefSeq Size: 2577
• RefSeq ORF: 1875
• Locus ID: 9817
• Domains: BTB, Kelch
• Protein Families: Transcription Factors
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) has an alternate 5' UTR, as compared to variant 1.