FNDC4 (NM_022823) Human Untagged Clone

CAT#: SC112412

FNDC4 (untagged)-Human fibronectin type III domain containing 4 (FNDC4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FNDC4
• Synonyms: FRCP1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112412 sequence for NM_022823 edited (data generated by NextGen Sequencing)
  ATGCCAAGCGGATGCCACAGTTCCCCCCCCAGCGGACTCCGTGGGGACATGGCTTCGCTG
  GTGCCCCTTTCCCCATATCTAAGCCCCACGGTCCTCCTGCTGGTCAGCTGTGACCTGGGC
  TTCGTGCGAGCAGACCGGCCTCCCTCTCCTGTGAATGTGACGGTCACTCACCTCAGAGCC
  AACTCGGCCACTGTGTCCTGGGACGTCCCAGAAGGCAACATCGTCATTGGCTACTCCATT
  TCCCAGCAACGGCAGAATGGCCCCGGGCAGCGTGTGATTCGGGAGGTGAACACCACCACC
  CGGGCCTGTGCCCTCTGGGGCCTGGCTGAAGACAGTGACTACACAGTGCAGGTCAGGAGC
  ATCGGCCTTCGGGGAGAGAGTCCCCCAGGGCCCCGGGTGCACTTCCGAACTCTCAAGGGT
  TCTGACCGGCTACCTTCAAACAGTTCAAGCCCAGGTGACATCACAGTGGAAGGTCTGGAT
  GGAGAGCGGCCACTGCAGACTGGGGAAGTGGTCATCATTGTGGTGGTGTTGCTCATGTGG
  GCTGCTGTAATTGGGCTGTTCTGCCGTCAGTATGACATCATCAAGGACAATGACTCCAAC
  AACAATCCCAAGGAGAAGGGAAAGGGGCCGGAACAGAGTCCTCAGGGAAGGCCAGTGGGG
  ACAAGACAGAAAAAGTCACCATCTATCAACACCATCGACGTTTGA
  
  Clone variation with respect to NM_022823.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022823 unedited
  TCGGATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCCAGGCCAGCG
  TCCGGGCAACGCCCCCTGCTCCCGGACAGACTCCGTGGCCCGCTCGAGCCCTGGGGGCTC
  CGCAGACCCGCGCCCGCTCCGCCCGCAGCTCGGCCCCGCGCTGCCCGCGTCGCCGGGCCC
  GCGCCGGGATGGGGTAGGGGCAGCGCCACCGAGTCGGGCGATGGGCCGCCCTCTGGGCAC
  CGAGCAGCCCCCCGAGGCCTGACCAACCGCGAGGACCGGCGGAGGAGCCCCGCCTGGATG
  TCAAGCGGATGCCAAGCGGATGCCACAGTTCCCCCCCCAGCGGACTCCGTGGGGACATGG
  CTTCGCTGGTGCCCCTTTCCCCATATCTAAGCCCCACGGTCCTCCTGCTGGTCAGCTGTG
  ACCTGNGCTTCGTGCGAGCAGACCGGCCTCCCTCTCCTGTGAATGTGACGGTCACTCACC
  TCAGAGCCAACTCGGCCACTGTGTCCTGGGACGTCCCAGAAGGCAACATCGTCATTGGCT
  ACTCCATTTCCCAGCAACGGCAGAATGGCCCCGGGCAGCGTGTGATTCGGGAGGTGAACA
  CCACCACCCGGGCCTGTGCCCTCTGGGGCCTGGCTGAAGACAGTGACTACACAGTGCAGG
  TCAGGAGCATCGGCCTTCGGGGAGAGAGTCCCCCCAGGCCCCGGNTGCACTTCCGAACTC
  TCAGGGNNTCTGACCGCTACCTTCAAACAGTTCAAGCCCAGGTGACATCACAGTGGAAGG
  TCTGGATGGGAGAGCGCCACTGCANACTGGGGAAGTGGGTCATCATGTGGTGGGTGTGCT
  CATGTGGGCTGCTGTAATTGGGGCTGTCTGCCGTCAGTATGACATCATCAAGGACAATGA
  CTCCCAACAACATCCCAAGGAGAAGGAAAGGNGNCNGNACAGAGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022823 unedited
  NTTCTTTGGCCGCGGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTTGTTTGTCCA
  AAAACCTTTATTGGAAAAATGTCCAACAAGTGATATCACTAGCAGCTGAAGGGGCTGCCA
  GGTGAGAGGGGGAGCACCTGAGGCTCCATGGAAGACATTGGAGTAGTGCAGTGCAGCATC
  TGCCTCTAGGGTCAGACAATTCCTTTTATTTGCTGGGGTAAGAGGAGTACCCACAGAAAC
  ACCCCTCTCTGAGGGCCAGAGGCAAGATGTGGGGCAGCTGGGGATGCTCAGAGTCCTGAT
  ACAGGTGAAATGGGGCCCCCATTTGGGACCTAATGGAGTAGGGTACAACTAGTGACTCTC
  CCCTGGACCGGGGAATGGAAGGAGATATCCCATCTGATATCCACTCCCCAGGTCCAGGGG
  CACAGACTCTGAACAGACCTACCTTCTGGCTCTGCTCACAGTGGAAAGAGGATGGGTACC
  AGGCCTGAGATTGTGGGAGTGGCATTACCCTCTGGGAGTCTCGGGCAGATCACCATCTTG
  GGCTCCCCCTGACCCCATCCCTATCCCCAGTTGTTAGTGCATCTCTCTTCTGGGTGTGTT
  TCTTCACTCAAACGTCGATGGTGTTGATAGATGGTGACTTTTTCTGTCTTGTCCCCACTG
  GCCCTTCCTGAGGACTCTGTTCCGGCCCCTTTCCCTTCTCCTTGGGATTGTTGNNTGGAG
  TCATTGGCCTTGATGATGTCATACTGACGGGCAGACAGCCCAATACCGCAGCCCACATGA
  AGCACACCACCCCATGATGACCACTTCCCAGCCTGCAGTGGCCGGTCTTCATCCAGACCT
  TCCTGGGGATGCACCTGGGCCTTGACTGGTTGAGGGGACCCGGCCAACCCTTGGAGATTC
  CGGAAGGGCCCCCGGCCCCTGGGGGACCCTCTCCCCGAAGGCGATGCTCCTGACTGCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022823
• ORF Size: 705 bp
• Insert Size: 1590
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022823.1, NP_073734.1
• RefSeq Size: 1649
• RefSeq ORF: 705
• Locus ID: 64838
• Domains: FN3
• Protein Families: Transmembrane
• Gene Summary: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. [UniProtKB/Swiss-Prot Function]