VPS11 (NM_021729) Human Untagged Clone

CAT#: SC112921

VPS11 (untagged)-Human vacuolar protein sorting 11 homolog (S. cerevisiae) (VPS11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS11
• Synonyms: END1; HLD12; hVPS11; PEP5; RNF108
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_021729, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCTACCTGCAGTGGCGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTGAAGGAGCCGCTGAGCA
  ATGATGGGGCCGCTCCCGGGGCCACACCTGCTTCTGGATCCGCTGCTTCCAAGTTCCTTTGCCTCCCTCC
  TGGCATCACTGTCTGCGACTCAGGCCGAGGGAGCCTGGTCTTTGGAGATATGGAAGGCCAGATCTGGTTC
  TTGCCACGTTCCCTACAGCTTACAGGCTTCCAAGCCTACAAACTACGGGTGACACACCTGTACCAACTGA
  AGCAGCACAATATTCTGGCATCTGTTGGAGAAGATGAAGAGGGCATCAACCCCTTGGTTAAGATCTGGAA
  CCTGGAGAAGAGAGATGGTGGCAATCCACTCTGCACTCGAATCTTCCCTGCTATTCCAGGAACAGAGCCA
  ACTGTTGTATCTTGTTTGACTGTCCATGAAAATCTCAACTTTATGGCCATTGGTTTCACAGATGGCAGTG
  TTACATTGAACAAAGGAGACATCACCCGGGACCGGCATAGCAAGACCCAGATTTTGCACAAGGGCAACTA
  TCCTGTAACTGGATTGGCCTTTCGCCAAGCAGGAAAGACCACTCACTTGTTTGTTGTGACAACAGAGAAC
  GTCCAGTCCTATATAGTTTCTGGAAAAGACTACCCTCGCGTGGAGTTGGACACCCATGGTTGTGGCCTGC
  GCTGCTCAGCCCTAAGTGACCCTTCTCAGGACCTGCAGTTCATTGTGGCCGGGGATGAGTGTGTCTACTT
  GTACCAGCCTGATGAACGTGGGCCCTGCTTCGCCTTTGAGGGCCATAAGCTCATTGCCCACTGGTTTAGA
  GGCTACCTTATCATTGTCTCCCGTGACCGGAAGGTTTCTCCCAAGTCAGAGTTTACCAGCAGGGATTCAC
  AGAGCTCCGACAAGCAGATTCTAAACATCTATGACCTGTGCAACAAGTTCATAGCCTATAGCACCGTCTT
  TGAGGATGTAGTGGATGTGCTTGCTGAGTGGGGCTCCCTGTACGTGCTGACGCGGGATGGGCGGGTCCAC
  GCACTGCAGGAGAAGGACACACAGACCAAACTGGAGATGCTGTTTAAGAAGAACCTATTTGAGATGGCGA
  TTAACCTTGCCAAGAGCCAGCATCTGGACAGTGATGGGCTGGCCCAGATTTTCATGCAGTATGGAGACCA
  TCTCTACAGCAAGGGCAACCACGATGGGGCTGTCCAGCAATATATCCGAACCATTGGAAAGTTGGAGCCA
  TCCTACGTGATCCGCAAGTTTCTGGATGCCCAGCGCATTCACAACCTGACTGCCTACCTGCAGACCCTGC
  ACCGACAATCCCTGGCCAATGCCGACCATACCACCCTGCTCCTCAACTGCTATACCAAGCTCAAGGACAG
  CTCGAAGCTGGAGGAGTTCATCAAGAAAAAGAGTGAGAGTGAAGTCCACTTTGATGTGGAGACAGCCATC
  AAGGTCCTCCGGCAGGCTGGCTACTACTCCCATGCCCTGTATCTGGCGGAGAACCATGCACATCATGAGT
  GGTACCTGAAGATCCAGCTAGAAGACATTAAGAATTATCAGGAAGCCCTTCGATACATCGGCAAGCTGCC
  TTTTGAGCAGGCAGAGAGCAACATGAAGCGCTACGGCAAGATCCTCATGCACCACATACCAGAGCAGACA
  ACTCAGTTGCTGAAGGGACTTTGTACTGATTATCGGCCCAGCCTCGAAGGCCGCAGCGATAGGGAGGCCC
  CAGGCTGCAGGGCCAACTCTGAGGAGTTCATCCCCATCTTTGCCAATAACCCGCGAGAGCTGAAAGCCTT
  CCTAGAGCACATGAGTGAAGTGCAGCCAGACTCACCCCAGGGGATCTACGACACACTCCTTGAGCTGCGA
  CTGCAGAACTGGGCCCACGAGAAGGATCCACAGGTCAAAGAGAAGCTTCACGCAGAGGCCATTTCCCTGC
  TGAAGAGTGGTCGCTTCTGCGACGTCTTTGACAAGGCCCTGGTCCTGTGCCAGATGCACGACTTCCAGGA
  TGGTGTCCTTTACCTTTATGAGCAGGGGAAGCTGTTCCAGCAGATCATGCACTACCACATGCAGCACGAG
  CAGTACCGGCAGGTCATCAGCGTGTGTGAGCGCCATGGGGAGCAGGACCCCTCCTTGTGGGAGCAGGCCC
  TCAGCTACTTCGCTCGCAAGGAGGAGGACTGCAAGGAGTATGTGGCAGCTGTCCTCAAGCATATCGAGAA
  CAAGAACCTCATGCCACCTCTTCTAGTGGTGCAGACCCTGGCCCACAACTCCACAGCCACACTCTCCGTC
  ATCAGGGACTACCTGGTCCAAAAACTACAGAAACAGAGCCAGCAGATTGCACAGGATGAGCTGCGGGTGC
  GGCGGTACCGAGAGGAGACCACCCGTATCCGCCAGGAGATCCAAGAGCTCAAGGCCAGTCCTAAGATTTT
  CCAAAAGACCAAGTGCAGCATCTGTAACAGTGCCTTGGAGTTGCCCTCAGTCCACTTCCTGTGTGGCCAC
  TCCTTCCACCAACACTGCTTTGAGAGTTACTCGGAAAGTGATGCTGACTGCCCCACCTGCCTCCCTGAAA
  ACCGGAAGGTCATGGATATGATCCGGGCCCAGGAACAGAAACGAGATCTCCATGATCAATTCCAGCATCA
  GCTCAAGTGCTCCAATGACAGCTTTTCTGTGATTGCTGACTACTTTGGCAGAGGTGTTTTCAACAAATTG
  ACTCTGCTGACCGACCCTCCCACAGCCAGACTGACCTCCAGCCTGGAGGCTGGGCTGCAACGCGACCTAC
  TCATGCACTCCAGGAGGGGCACTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021729 unedited
  GTAATACGACTCACTATAGNNGGCGGCCGCGCAATTCGGCACGAGGCTGGGCCAAAATGG
  CGGCCTACCTGCAGTGGCGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTGAAGGAGCCGC
  TGAGCAATGATGGGGCCGCTCCCGGGGCCACACCTGCTTCTGGATCCGCTGCTTCCAAGT
  TCCTTTGCCTCCCTCCTGGCATCACTGTCTGCGACTCAGGCCGAGGGAGCCTGGTCTTTG
  GAGATATGGAAGGCCAGATCTGGTTCTTGCCACGTTCCCTACAGCTTACAGGCTTCCAAG
  CCTACAAACTACGGGTGACACACCTGTACCAACTGAAGCAGCACAATATTCTGGCATCTG
  TTGGAGAAGATGAAGAGGGCATCAACCCCTTGGTTAAGATCTGGAACCTGGAGAAGAGAG
  ATGGTGGCAATCCACTCTGCACTCGAATCTTCCCTGCTATTCCAGGAACAGAGCCAACTG
  TTGTATCTTGTTTGACTGTCCATGAAAATCTCAACTTTATGGCCATTGGTTTCACAGATG
  GGAGTGTTACATTGAACAAAGGAGACATCACCCGGGACCGGCATAGCAAGACCCAGATTT
  TGCACAAGGGCAACTATCCTGTAACTGGATTGGCCTTTCGCCAAGCAGGAAAGACCACTC
  ACTTGTTTGTTGTGACAACAGAAGAACGTCCAGTCAGAGTTTACCAGCAGGGATTCACAG
  AGCTCCCGACAGCAGATTCTAAACATCTATGACCTGTGCAACAAGTTCATAGCCTATAGC
  ACCGTCTTTTGAGATGTAAGGGATGTGCTTGCTGAATGGGGCTCCCTGTACTTGCTGACG
  CGGGATGGGCGGTTCCACGCCCTGCNGGAGAGGGACCACAGACCCAACTGGGGATGCTGT
  TTAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021729 unedited
  GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAATTATATTCTTTTATTTATAG
  ACTCTGAGAGCAAGGACCCAAGCACAGCCTGGTGCTCTTGGATAGAGAAAAAAGCAGCTA
  TTGTCCACACTCAGAGGTTGCTGAGGTGCCCTCCCCCACTGATCTGGAATGATCTACACT
  GCTAGTGAAGAGGAGGGATGGCAAGCTGACTAAATAAGAAGGCAGGGAAAGAAAGTCCGC
  TTTAGTTCTGAGGGCTGTGACATTAGATGAGAGTGGAGCCCTGGGCATGTCAGCCAGCCT
  TCTGTGTAACGCCCGCCCAGGTCCCATTGTGTCTGTTCTCTCGGTCCTCCACTGTTGCCC
  ACATCTTCCTCCAGGCTGCTTAAGTGCCCCTCCTGGAGTGCATGAGTAGGTCGCGTTGCA
  GCCCAGCCTCCAGGCTGGAGGTCAGTCTGGCTGTGGGAGGGTCGGTCAGCAGAGTCAATT
  TGTTGAAAACACCTCTGCCAAAGTAGTCAGCAATCACAGAAAAGCTGTCATTGGAGCACC
  TGAGCTGATGCTGGAATTGATCATGGAGATCTCGTTTCTGTTCCTGGGCCCCGATCATAT
  CCATGACCTTTCGGTTTTCAGGGAGGCAGGNTGGGCAGTCAGCATCACTTTCCGAGTAAC
  TCTCAAAGCAGTGTTGGTGGCACGAGCTGGCACACAAGAAGTGGACCTGAGGCAACTCCA
  AGCACTGTACAAATGCTGACTTGGCCTTTTGAAAATCTAGGACTGCCCTGACCTTTGGAC
  CCCTGGCGGACGGGTGGTCTCCTCTGGACCCGCCCCCCCGAATTAACCTGGCAATCGGTG
  GCTTGTTTCTGATTTTTGACCACATATCCTTTAACAGAAATGGGCCTGGAATTGTGGCCA
  GGTCTCCCCCTAAAAAGGGCCTGAGGCTCTGTCCCACATCTAG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021729
• ORF Size: 2826 bp
• Insert Size: 3800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021729.4, NP_068375.3
• RefSeq Size: 3279
• RefSeq ORF: 2826
• Locus ID: 55823
• Domains: Clathrin, RING
• Protein Families: Druggable Genome
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (1) encodes the longer isoform (1).