VPS11 (NM_021729) Human Untagged Clone

CAT#: SC324062

VPS11 (untagged)-Human vacuolar protein sorting 11 homolog (S. cerevisiae) (VPS11)


  "NM_021729" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol VPS11
Synonyms END1; HLD12; hVPS11; PEP5; RNF108
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_021729.4 GCCAAAATGGCGGCCTACCTGCAGTGGCGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTG
AAGGAGCCGCTGAGCAATGATGGGGCCGCTCCCGGGGCCACACCTGCTTCTGGATCCGCT
GCTTCCAAGTTCCTTTGCCTCCCTCCTGGCATCACTGTCTGCGACTCAGGCCGAGGGAGC
CTGGTCTTTGGAGATATGGAAGGCCAGATCTGGTTCTTGCCACGTTCCCTACAGCTTACA
GGCTTCCAAGCCTACAAACTACGGGTGACACACCTGTACCAACTGAAGCAGCACAATATT
CTGGCATCTGTTGGAGAAGATGAAGAGGGCATCAACCCCTTGGTTAAGATCTGGAACCTG
GAGAAGAGAGATGGTGGCAATCCACTCTGCACTCGAATCTTCCCTGCTATTCCAGGAACA
GAGCCAACTGTTGTATCTTGTTTGACTGTCCATGAAAATCTCAACTTTATGGCCATTGGT
TTCACAGATGGGAGTGTTACATTGAACAAAGGAGACATCACCCGGGACCGGCATAGCAAG
ACCCAGATTTTGCACAAGGGCAACTATCCTGTAACTGGATTGGCCTTTCGCCAAGCAGGA
AAGACCACTCACTTGTTTGTTGTGACAACAGAGAACGTCCAGTCCTATATAGTTTCTGGA
AAAGACTACCCTCGCGTGGAGTTGGACACCCATGGTTGTGGCCTGCGCTGCTCAGCCCTA
AGTGACCCTTCTCAGGACCTGCAGTTCATTGTGGCCGGGGATGAGTGTGTCTACTTGTAC
CAGCCTGATGAACGTGGGCCCTGCTTCGCCTTTGAGGGCCATAAGCTCATTGCCCACTGG
TTTAGAGGCTACCTTATCATTGTCTCCCGTGACCGGAAGGTTTCTCCCAAGTCAGAGTTT
ACCAGCAGGGATTCACAGAGCTCCGACAAGCAGATTCTAAACATCTATGACCTGTGCAAC
AAGTTCATAGCCTATAGCACCGTCTTTGAGGATGTAGTGGATGTGCTTGCTGAGTGGGGC
TCCCTGTACGTGCTGACGCGGGATGGGCGGGTCCACGCACTGCAGGAGAAGGACACACAG
ACCAAACTGGAGATGCTGTTTAAGAAGAACCTATTTGAGATGGCGATTAACCTTGCCAAG
AGCCAGCATCTGGACAGTGATGGGCTGGCCCAGATTTTCATGCAGTATGGAGACCATCTC
TACAGCAAGGGCAACCACGATGGGGCTGTCCAGCAATATATCCGAACCATTGGAAAGTTG
GAGCCATCCTACGTGATCCGCAAGTTTCTGGATGCCCAGCGCATTCACAACCTGACTGCC
TACCTGCAGACCCTGCACCGACAATCCCTGGCCAATGCCGACCATACCACCCTGCTCCTC
AACTGCTATACCAAGCTCAAGGACAGCTCGAAGCTGGAGGAGTTCATCAAGAAAAAGAGT
GAGAGTGAAGTCCACTTTGATGTGGAGACAGCCATCAAGGTCCTCCGGCAGGCTGGCTAC
TACTCCCATGCCCTGTATCTGGCGGAGAACCATGCACATCATGAGTGGTACCTGAAGATC
CAGCTAGAAGACATTAAGAATTATCAGGAAGCCCTTCGATACATCGGCAAGCTGCCTTTT
GAGCAGGCAGAGAGCAACATGAAGCGCTACGGCAAGATCCTCATGCACCACATACCAGAG
CAGACAACTCAGTTGCTGAAGGGACTTTGTACTGATTATCGGCCCAGCCTCGAAGGCCGC
AGCGATAGGGAGGCCCCAGGCTGCAGGGCCAACTCTGAGGAGTTCATCCCCATCTTTGCC
AATAACCCGCGAGAGCTGAAAGCCTTCCTAGAGCACATGAGTGAAGTGCAGCCAGACTCA
CCCCAGGGGATCTACGACACACTCCTTGAGCTGCGACTGCAGAACTGGGCCCACGAGAAG
GATCCACAGGTCAAAGAGAAGCTTCACGCAGAGGCCATTTCCCTGCTGAAGAGTGGTCGC
TTCTGTGACGTCTTTGACAAGGCCCTGGTCCTGTGCCAGATGCACGACTTCCAGGATGGT
GTCCTTTACCTTTATGAGCAGGGGAAGCTGTTCCAGCAGATCATGCACTACCACATGCAG
CACGAGCAGTACCGGCAGGTCATCAGCGTGTGTGAGCGCCATGGGGAGCAGGACCCCTCC
TTGTGGGAGCAGGCCCTCAGCTACTTCGCTCGCAAGGAGGAGGACTGCAAGGAGTATGTG
GCAGCTGTCCTCAAGCATATCGAGAACAAGAACCTCATGCCACCTCTTCTAGTGGTGCAG
ACCCTGGCCCACAACTCCACAGCCACACTCTCCGTCATCAGGGACTACCTGGTCCAAAAA
CTACAGAAACAGAGCCAGCAGATTGCACAGGATGAGCTGCGGGTGCGGCGGTACCGAGAG
GAGACCACCCGTATCCGCCAGGAGATCCAAGAGCTCAAGGCCAGTCCTAAGATTTTCCAA
AAGACCAAGTGCAGCATCTGTAACAGTGCCTTGGAGTTGCCCTCAGTCCACTTCCTGTGT
GGCCACTCCTTCCACCAACACTGCTTTGAGAGTTACTCGGAAAGTGATGCTGACTGCCCC
ACCTGCCTCCCTGAAAACCGGAAGGTCATGGATATGATCCGGGCCCAGGAACAGAAACGA
GATCTCCATGATCAATTCCAGCATCAGCTCAGGTGCTCCAATGACAGCTTTTCTGTGATT
GCTGACTACTTTGGCAGAGGTGTTTTCAACAAATTGACTCTGCTGACCGACCCTCCCACA
GCCAGACTGACCTCCAGCCTGGAGGCTGGGCTGCAACGCGACCTACTCATGCACTCCAGG
AGGGGCACTTAAGCAGCCTGGAGGAAGATGTGGGCAACAGTGGAGGACCGAGAGAACAGA
CACAATGGGACCTGGGCGGGCGTTACACAGAAGGCTGGCTGACATGCCCAGGGCTCCACT
CTCATCTAATGTCACAGCCCTCAGAACTAAAGCGGACTTTCTTTCCCTGCCTTCTTATTT
AGTCAGCTTGCCATCCCTCCTCTTCACTAGCAGTGTAGATCATTCCAGATCAGTGGGGGA
GGGCACCTCAGCAACCTCTGAGTGTGGACAATAGCTGCTTTCTTCTCTATCCAAGAGCAC
CAGGCTGTGCTTGGGTCCTTGCTCTCAGAGTCTATAAATAAAAGAATATAATGATTTGGG
AGCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA
>OriGene 5' read for NM_021729.4 unedited
GGCGTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
GAATTCCCGGGATATCGTCGACCCACGCGTCCGGCCAAAATGGCGGCCTACCTGCAGTGG
CGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTGAAGGAGCCGCTGAGCAATGATGGGGCC
GCTCCCGGGGCCACACCTGCTTCTGGATCCGCTGCTTCCAAGTTCCTTTGCCTCCCTCCT
GGCATCACTGTCTGCGACTCAGGCCGAGGGAGCCTGGTCTTTGGAGATATGGAAGGCCAG
ATCTGGTTCTTGCCACGTTCCCTACAGCTTACAGGCTTCCAAGCCTACAAACTACGGGTG
ACACACCTGTACCAACTGAAGCAGCACAATATTCTGGCATCTGTTGGAGAAGATGAAGAG
GGCATCAACCCCTTGGTTAAGATCTGGAACCTGGAGAAGAGAGATGGTGGCAATCCACTC
TGCACTCGAATCTTCCCTGCTATTCCAGGAACAGAGCCAACTGTTGTATCTTGTTTGACT
GTCCATGAAAATCTCAACTTTATGGCCATTGGTTTCACAGATGGGAGTGTTACATTGAAC
AAAGGAGACATCACCCGGGACCGGCATAGCAAGACCCAGATTTTGCACAAGGGCAACTAT
CCTGTAACTGGATTGGCCTTTCGCCAAGCAGGAAAGACCACTCACTTGTTTGTTGTGACA
CAGAGAACGTCCAGTCCTATATAGTTTCTGGAAAAGACTACCCTCGCGTGGAGTTGGACA
CCCATGGTTGTGGCCCTGCGCTGCTCAGCCCTAAGTGACCCTTCTCAGGACCTGCAGTCA
TGTGCCCGGGATGAGTGTGTCTACTTGTACCAGCCTGATGAACGTGGACCTGCTTCGCCT
TTGAAGGCCATAAGCTCATGCCACTGCTAAGGCCTACTTATCATGTCTTCCCGTGACCGG
AAGTTCTCCCAAGTTCAGAGATTTAC
Restriction Sites ECoRI-NOT     
ACCN NM_021729
ORF Size 2826 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_021729.4, NP_068375.3
RefSeq Size 3279
RefSeq ORF 2826
Locus ID 55823
Domains Clathrin, RING
Protein Families Druggable Genome
Gene Summary Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Transcript Variant: This variant (1) encodes the longer isoform (1).

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