VPS11 (NM_021729) Human Untagged Clone

CAT#: SC324062

VPS11 (untagged)-Human vacuolar protein sorting 11 homolog (S. cerevisiae) (VPS11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS11
• Synonyms: END1; HLD12; hVPS11; PEP5; RNF108
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021729.4 GCCAAAATGGCGGCCTACCTGCAGTGGCGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTG
  AAGGAGCCGCTGAGCAATGATGGGGCCGCTCCCGGGGCCACACCTGCTTCTGGATCCGCT
  GCTTCCAAGTTCCTTTGCCTCCCTCCTGGCATCACTGTCTGCGACTCAGGCCGAGGGAGC
  CTGGTCTTTGGAGATATGGAAGGCCAGATCTGGTTCTTGCCACGTTCCCTACAGCTTACA
  GGCTTCCAAGCCTACAAACTACGGGTGACACACCTGTACCAACTGAAGCAGCACAATATT
  CTGGCATCTGTTGGAGAAGATGAAGAGGGCATCAACCCCTTGGTTAAGATCTGGAACCTG
  GAGAAGAGAGATGGTGGCAATCCACTCTGCACTCGAATCTTCCCTGCTATTCCAGGAACA
  GAGCCAACTGTTGTATCTTGTTTGACTGTCCATGAAAATCTCAACTTTATGGCCATTGGT
  TTCACAGATGGGAGTGTTACATTGAACAAAGGAGACATCACCCGGGACCGGCATAGCAAG
  ACCCAGATTTTGCACAAGGGCAACTATCCTGTAACTGGATTGGCCTTTCGCCAAGCAGGA
  AAGACCACTCACTTGTTTGTTGTGACAACAGAGAACGTCCAGTCCTATATAGTTTCTGGA
  AAAGACTACCCTCGCGTGGAGTTGGACACCCATGGTTGTGGCCTGCGCTGCTCAGCCCTA
  AGTGACCCTTCTCAGGACCTGCAGTTCATTGTGGCCGGGGATGAGTGTGTCTACTTGTAC
  CAGCCTGATGAACGTGGGCCCTGCTTCGCCTTTGAGGGCCATAAGCTCATTGCCCACTGG
  TTTAGAGGCTACCTTATCATTGTCTCCCGTGACCGGAAGGTTTCTCCCAAGTCAGAGTTT
  ACCAGCAGGGATTCACAGAGCTCCGACAAGCAGATTCTAAACATCTATGACCTGTGCAAC
  AAGTTCATAGCCTATAGCACCGTCTTTGAGGATGTAGTGGATGTGCTTGCTGAGTGGGGC
  TCCCTGTACGTGCTGACGCGGGATGGGCGGGTCCACGCACTGCAGGAGAAGGACACACAG
  ACCAAACTGGAGATGCTGTTTAAGAAGAACCTATTTGAGATGGCGATTAACCTTGCCAAG
  AGCCAGCATCTGGACAGTGATGGGCTGGCCCAGATTTTCATGCAGTATGGAGACCATCTC
  TACAGCAAGGGCAACCACGATGGGGCTGTCCAGCAATATATCCGAACCATTGGAAAGTTG
  GAGCCATCCTACGTGATCCGCAAGTTTCTGGATGCCCAGCGCATTCACAACCTGACTGCC
  TACCTGCAGACCCTGCACCGACAATCCCTGGCCAATGCCGACCATACCACCCTGCTCCTC
  AACTGCTATACCAAGCTCAAGGACAGCTCGAAGCTGGAGGAGTTCATCAAGAAAAAGAGT
  GAGAGTGAAGTCCACTTTGATGTGGAGACAGCCATCAAGGTCCTCCGGCAGGCTGGCTAC
  TACTCCCATGCCCTGTATCTGGCGGAGAACCATGCACATCATGAGTGGTACCTGAAGATC
  CAGCTAGAAGACATTAAGAATTATCAGGAAGCCCTTCGATACATCGGCAAGCTGCCTTTT
  GAGCAGGCAGAGAGCAACATGAAGCGCTACGGCAAGATCCTCATGCACCACATACCAGAG
  CAGACAACTCAGTTGCTGAAGGGACTTTGTACTGATTATCGGCCCAGCCTCGAAGGCCGC
  AGCGATAGGGAGGCCCCAGGCTGCAGGGCCAACTCTGAGGAGTTCATCCCCATCTTTGCC
  AATAACCCGCGAGAGCTGAAAGCCTTCCTAGAGCACATGAGTGAAGTGCAGCCAGACTCA
  CCCCAGGGGATCTACGACACACTCCTTGAGCTGCGACTGCAGAACTGGGCCCACGAGAAG
  GATCCACAGGTCAAAGAGAAGCTTCACGCAGAGGCCATTTCCCTGCTGAAGAGTGGTCGC
  TTCTGTGACGTCTTTGACAAGGCCCTGGTCCTGTGCCAGATGCACGACTTCCAGGATGGT
  GTCCTTTACCTTTATGAGCAGGGGAAGCTGTTCCAGCAGATCATGCACTACCACATGCAG
  CACGAGCAGTACCGGCAGGTCATCAGCGTGTGTGAGCGCCATGGGGAGCAGGACCCCTCC
  TTGTGGGAGCAGGCCCTCAGCTACTTCGCTCGCAAGGAGGAGGACTGCAAGGAGTATGTG
  GCAGCTGTCCTCAAGCATATCGAGAACAAGAACCTCATGCCACCTCTTCTAGTGGTGCAG
  ACCCTGGCCCACAACTCCACAGCCACACTCTCCGTCATCAGGGACTACCTGGTCCAAAAA
  CTACAGAAACAGAGCCAGCAGATTGCACAGGATGAGCTGCGGGTGCGGCGGTACCGAGAG
  GAGACCACCCGTATCCGCCAGGAGATCCAAGAGCTCAAGGCCAGTCCTAAGATTTTCCAA
  AAGACCAAGTGCAGCATCTGTAACAGTGCCTTGGAGTTGCCCTCAGTCCACTTCCTGTGT
  GGCCACTCCTTCCACCAACACTGCTTTGAGAGTTACTCGGAAAGTGATGCTGACTGCCCC
  ACCTGCCTCCCTGAAAACCGGAAGGTCATGGATATGATCCGGGCCCAGGAACAGAAACGA
  GATCTCCATGATCAATTCCAGCATCAGCTCAGGTGCTCCAATGACAGCTTTTCTGTGATT
  GCTGACTACTTTGGCAGAGGTGTTTTCAACAAATTGACTCTGCTGACCGACCCTCCCACA
  GCCAGACTGACCTCCAGCCTGGAGGCTGGGCTGCAACGCGACCTACTCATGCACTCCAGG
  AGGGGCACTTAAGCAGCCTGGAGGAAGATGTGGGCAACAGTGGAGGACCGAGAGAACAGA
  CACAATGGGACCTGGGCGGGCGTTACACAGAAGGCTGGCTGACATGCCCAGGGCTCCACT
  CTCATCTAATGTCACAGCCCTCAGAACTAAAGCGGACTTTCTTTCCCTGCCTTCTTATTT
  AGTCAGCTTGCCATCCCTCCTCTTCACTAGCAGTGTAGATCATTCCAGATCAGTGGGGGA
  GGGCACCTCAGCAACCTCTGAGTGTGGACAATAGCTGCTTTCTTCTCTATCCAAGAGCAC
  CAGGCTGTGCTTGGGTCCTTGCTCTCAGAGTCTATAAATAAAAGAATATAATGATTTGGG
  AGCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021729.4 unedited
  GGCGTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGGCCAAAATGGCGGCCTACCTGCAGTGG
  CGGCGCTTCGTTTTCTTCGACAAGGAGCTGGTGAAGGAGCCGCTGAGCAATGATGGGGCC
  GCTCCCGGGGCCACACCTGCTTCTGGATCCGCTGCTTCCAAGTTCCTTTGCCTCCCTCCT
  GGCATCACTGTCTGCGACTCAGGCCGAGGGAGCCTGGTCTTTGGAGATATGGAAGGCCAG
  ATCTGGTTCTTGCCACGTTCCCTACAGCTTACAGGCTTCCAAGCCTACAAACTACGGGTG
  ACACACCTGTACCAACTGAAGCAGCACAATATTCTGGCATCTGTTGGAGAAGATGAAGAG
  GGCATCAACCCCTTGGTTAAGATCTGGAACCTGGAGAAGAGAGATGGTGGCAATCCACTC
  TGCACTCGAATCTTCCCTGCTATTCCAGGAACAGAGCCAACTGTTGTATCTTGTTTGACT
  GTCCATGAAAATCTCAACTTTATGGCCATTGGTTTCACAGATGGGAGTGTTACATTGAAC
  AAAGGAGACATCACCCGGGACCGGCATAGCAAGACCCAGATTTTGCACAAGGGCAACTAT
  CCTGTAACTGGATTGGCCTTTCGCCAAGCAGGAAAGACCACTCACTTGTTTGTTGTGACA
  CAGAGAACGTCCAGTCCTATATAGTTTCTGGAAAAGACTACCCTCGCGTGGAGTTGGACA
  CCCATGGTTGTGGCCCTGCGCTGCTCAGCCCTAAGTGACCCTTCTCAGGACCTGCAGTCA
  TGTGCCCGGGATGAGTGTGTCTACTTGTACCAGCCTGATGAACGTGGACCTGCTTCGCCT
  TTGAAGGCCATAAGCTCATGCCACTGCTAAGGCCTACTTATCATGTCTTCCCGTGACCGG
  AAGTTCTCCCAAGTTCAGAGATTTAC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021729
• ORF Size: 2826 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021729.4, NP_068375.3
• RefSeq Size: 3279
• RefSeq ORF: 2826
• Locus ID: 55823
• Domains: Clathrin, RING
• Protein Families: Druggable Genome
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (1) encodes the longer isoform (1).