Neuromedin B (NMB) (NM_021077) Human Untagged Clone

CAT#: SC113025

NMB (untagged)-Human neuromedin B (NMB), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NMB
• Synonyms: MGC2277; MGC3936; MGC17211
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113025 sequence for NM_021077 edited (data generated by NextGen Sequencing)
  ATGGCCCGGCGGGCGGGGGGCGCTCGGATGTTCGGCAGCCTCCTGCTCTTCGCCCTGCTC
  GCTGCCGGCGTCGCCCCGCTCAGCTGGGATCTCCCGGAGCCCCGCAGCCGAGCCAGCAAG
  ATCCGAGTGCACTCGCGAGGCAACCTCTGGGCCACCGGTCACTTCATGGGCAAGAAGAGT
  CTGGAGCCTTCCAGCCCATCCCCATTGGGGACAGCTCCCCACACCTCCCTGAGGGACCAG
  CGACTGCAGCTGAGTCATGATCTGCTCGGAATCCTCCTGCTAAAGAAGGCTCTGGGCGTG
  AGCCTCAGCCGCCCCGCACCCCAAATCCAGTACAGGAGGCTGCTGGTACAAATACTGCAG
  AAATGA
  
  Clone variation with respect to NM_021077.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021077 unedited
  NTTGTCAGAATTTGTATACGACTCATATAGGCGGCCGCGNAATCGGCACGAGGGTCTCTG
  GGCGGCCCAAGGGGGTGCCCCTGCCTGGTAACCTAGCGGGAGGGTGGGGACGGCGGGGAG
  GGCGGCGGGCGCGGGGCACGGCTCCGCTGCTCAGGGCAGGCTCCGCCCCCAGGGGCGCGG
  ACTTAAAAGGATCGAAGGCAGCCCCGGAGCCCAGCGGCCGGGAAGCGCGCCCGAACGAAG
  CCGCGGCCCGGGCACAGCCATGGCCCGGCGGGCGGGGGGCGCTCGGATGTTCGGCAGCCT
  CCTGCTCTTCGCCCTGCTCGCTGCCGGCGTCGCCCCGCTCAGCTGGGATCTCCCGGAGCC
  CCGCAGCCGAGCCAGCAAGATCCGAGTGCACTCGCGAGGCAACCTCTGGGCCACCGGTCA
  CTTCACGGGCAAGAAGAGTCTGGAGCCTTCCAGCCCATCCCCATTGGGGACAGCTCCCCA
  CACCTCCCTGAGGGACCAGCGACTGCAGCTGAGTCATGATCTGCTCGGAATCCTCCTGCT
  AAAGAAGGCTCTGGGCGTGAGCCTCAGCCGCCCCGCACCCCAAATCCAGTACAGGAGGCT
  GCTGGTACAAATACTGCAGAAATGACACCAATAATGGGGCAGACACAACAGCGTGGCTTA
  GATTGTGCCCACCCAGGGAAGGTGCTGAATGGGACCCTGTTGATGGCCCCATCTGGATGT
  AAATCCTGAGCTCANATCTCTGTTACTCCATTACTGTGATTTCTGGCTGGGTCAACTAGA
  ATATCGCTGATGCAGACACAGATTATGTTCCTGCTGTATTTCCTGCTTCCCTGTTGAATT
  GGTGAATAAAACCTTGCTCTTTACATAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021077 unedited
  GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATGTAAAGAGCAAGGTTTTATTCACC
  AATTCAACAGGNGAAGCAGGAAATACAGCAGGAACATAATCTGTGTCTGCATCAGCGATA
  TTTCTGGTGACCCAGCCAGAAATCACAGTAATGGAGTAACAGAGATTTGAGCTCAGGATT
  TACATCCAGATGGGGCCATCAACAGGGTCCCATTCAGCACCTTCCCTGGGTGGGCACAAT
  CTAAGCCACGCTGTTGTGTCTGCCCCATTATTGGTGTCATTTCTGCAGTATTTGTACCAG
  CAGCCTCCTGTACTGGATTTGGGGTGCGGNGCGGCTGAGGCTCACGCCCAGAGCCTTCTT
  TAGCAGGAGGATTCCGAGCAGATCATGACTCAGCTGCAGTCGCTGGTCCCTCAGGGAGGT
  GTGGGGAGCTGTCCCCAATGGGGATGGGCTGGAAGGCTCCAGACTCTTCTTGCCCATGAA
  GTGACCGGTGGCCCAGAGGTTGCCTCGCGAGTGCACTNCGATCTTGCTGGCTCGGCTGCG
  GNGCTCCGGGAGATCCCAGCTGAGCGGNGCGACGCCGGCAGCGAGCAGGGCGAAGAGCAG
  GAGGCTGCCGAACTCCCGAGCGCCCCCCGCCCCGCCGGCCATGGNCTGTGCCCCGGGCCG
  CNGGCTTNCGTTCGGGGCGCGCTTCCCGGGCCGCTGGGCTTCGGGNGCTGCCTTNCGATC
  CTTTTAAATCCGCGCCCTGNGGGCGGAGCCTGCCCTGACAGNGNAGCCTGNCCCNGGGCC
  CGNGGGCCTTCCGGGGGGTCCCACCTTTCGGTTAGGTACCCAGCAGGGGCACCCCTTTGG
  GCCGCCCAAGACCCTCTGCCCGATTCCGGGCGCCTTTAGTGAGTCGTATACAAAATTTGA
  CGGTTACTAAACGAGCTCTGCTTATTAGACCTCCCACGTACACGCTACCGCCATTTGCGT
  ACGGGGCGGGTTATACGAATTTGGAAAGCCCGTGAATTTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021077
• Insert Size: 860 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021077.3, NP_066563.2
• RefSeq Size: 1046 bp
• RefSeq ORF: 366 bp
• Locus ID: 4828
• Cytogenetics: 15q25.2
• Domains: Bombesin
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: 'This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]'
  Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1).