EIF2B3 (NM_020365) Human Untagged Clone

CAT#: SC113103

EIF2B3 (untagged)-Human eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (EIF2B3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EIF2B3
• Synonyms: EIF-2B; EIF2Bgamma
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113103 sequence for NM_020365 edited (data generated by NextGen Sequencing)
  ATGGAATTTCAAGCAGTAGTGATGGCAGTAGGTGGAGGATCTCGGATGACAGACCTAACT
  TCCAGCATTCCCAAACCTCTGCTTCCAGTTGGGAACAAACCTTTAATTTGGTACCCATTG
  AACCTGCTTGAGCGTGTTGGATTTGAAGAAGTCATTGTGGTTACAACCAGGGATGTTCAA
  AAGGCTCTATGTGCAGAATTCAAGATGAAAATGAAGCCAGATATTGTGTGTATTCCTGAT
  GATGCTGACATGGGAACTGCAGATTCTTTGCGCTACATATATCCAAAACTTAAGACAGAT
  GTGCTGGTGCTGAGCTGTGATCTGATAACAGACGTTGCCTTACATGAGGTTGTGGACCTG
  TTTAGAGCTTATGATGCATCACTTGCTATGTTGATGAGAAAAGGCCAAGATAGCATAGAA
  CCTGTTCCCGGTCAAAAGGGGAAAAAAAAAGCAGTGGAGCAGCGTGACTTCATTGGAGTG
  GACAGCACAGGAAAGAGGCTGCTCTTCATGGCTAATGAAGCAGACTTGGATGAAGAGCTG
  GTCATTAAGGGATCCATCCTACAGAAGCATCCTAGAATACGTTTCCACACGGGTCTTGTG
  GATGCCCACCTCTACTGTTTGAAAAAATACATCGTGGATTTCCTAATGGAAAATGGGTCA
  ATAACTTCTATCCGGAGTGAACTGATTCCATATTTAGTGAGAAAACAGTTTTCCTCAGCT
  TCCTCACAACAGGGACAAGAAGAAAAAGAGGAGGATCTAAAGAAAAAGGAGCTGAAGTCC
  TTAGATATCTACAGTTTTATAAAAGAAGCCAATACACTGAACCTGGCTCCCTATGATGCC
  TGCTGGAATGCCTGTCGAGGAGACAGGTGGGAAGACTTGTCCAGATCACAGGTGCGCTGC
  TATGTCCACATCATGAAAGAGGGGCTCTGCTCTCGAGTGAGCACACTGGGACTCTACATG
  GAAGCAAACAGACAGGTGCCCAAATTGCTGTCTGCTCTCTGTCCAGAAGAACCACCAGTC
  CATTCGTCAGCCCAGATTGTCAGCAAACACCTGGTTGGAGTTGACAGCCTCATTGGGCCA
  GAGACACAGATTGGAGAGAAGTCATCCATTAAGCGCTCAGTCATTGGCTCATCCTGTCTC
  ATAAAAGATAGAGTGACTATTACCAATTGCCTTCTCATGAACTCAGTCACTGTGGAGGAA
  GGAAGCAATATCCAAGGCAGTGTCATCTGCAACAATGCTGTGATCGAGAAGGGTGCAGAC
  ATCAAGGACTGCTTGATTGGAAGTGGCCAGAGGATTGAAGCCAAAGCTAAACGAGTGAAT
  GAGGTGATCGTGGGGAATGACCAGCTCATGGAGATCTGA
  
  Clone variation with respect to NM_020365.3
  243 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020365 unedited
  CACATTTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGGCGTGCGGGG
  AGCTGAGTTATAGCTGTGACTTCTGCCCTGCCAGGCCGCACACAAGCTGGCTGACCCGGT
  TTGTAAAAATGGAATTTCAAGCAGTAGTGATGGCAGTAGGTGGAGGATCTCGGATGACAG
  ACCTAACTTCCAGCATTCCCAAACCTCTGCTTCCAGTTGGGAACAAACCTTTAATTTGGT
  ACCCATTGAACCTGCTTGAGCGTGTTGGATTTGAAGAAGTCATTGTGGTTACAACCAGGG
  ATGTTCAAAAGGCTCTATGTGCAGAATTCAAGATGAAAATGAAGCCAGATATTGTGTGTA
  TTCCTGATGATGCTGACATGGGAACTGCAGATTCTTTGCGCTACATATATCCAAAACTTA
  AGACAGATGTGCTGGTGCTGAGCTGTGATCTGATAACAGACGTTGCCTTACATGAGGTTG
  TGGACCTGTTTAGAGCTTATGATGCATCACTTGCTATGTTGATGAGAAAAGGCCAAGATA
  GCATAGAACCTGTTCCCGGTCAAAAGGGGAAAAAAAAAGCAGTGGAGCAGCGTGACTTCA
  TTGGAGTGGACAGCACAGGAAAGAGGCTGCTCTTCATGGCTAATGAAGCAGACTTGGATG
  AAGAGCTGGTCATTAAGGGATCCATCCTACAGAAGCATCCTAGAATACGTTTCCACACGG
  GNTCTTGTGGATGCCCACCTCTACTGTTNGAAAAATACATCGTGGATTTCCTAATGGAAA
  ATGGGNNTCATACTTCTATCCNNGAGTGACTGNATNNCATATTAGTGANGAAACAGTTTT
  TCTCAGCTTCCCCTCACACAGGGACCAGAAGAAAAGAGNAGGATCTAANGAAAAGGAGNN
  CTGAGTCNTAGTATCTACANTTTTATAAAGAAGCCATACACTGAACTGGNCTCCTATGAT
  GCTGCTGNAATGCTGTCNAGGAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020365 unedited
  GATCGCTGCCGCAATTTANATCTAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTACCCCTGGGACCCCACCTGACATGGGACCTTTGGACTGGTC
  CACAAGTCTCCAGCATGCCTTTGGAAGCCCTTTTTTATTGGGAAATAAATACCGAGTTAA
  ACAGGGGGGCCGGCCAACATCTGGGGCTTTTTAGGCCAAAAGGAAGGAGTCTGACTTGGT
  CAAAACTCAAATCTCCATGAGCTGGTCATTCCCCACGATCACCTCATTCACTCGTTTAGC
  TTTGGCTTCAATCCTTTGGCCACTTCCAATCAAGCAGTCCTTGATGTCTGCCCCCTTTTC
  GATCACAGCATTGTTGCAAATGACACTGCCTTGGATATTGCTTCCTTCCTCCCAGGGACT
  GAGTTCATGAAAAGGCAATTGGGAATAGTCACTCTATCTTTTATGAAACAGGATGAGCCA
  ATGACTGAGCGCTTAATGGATGACTTCTCTCCAATCTGTGTCTCTGGCCCAATGAGGCTG
  TCAACTCCAACCAGGTGTTTGCTGACAATCTGGGCTGACCAATGGACTGGTGGTTCTTCT
  GGACAGAAAGCACACAGCAATTTGGGCACCTGTCTGTTTTGCTCCATGTAGAGTCCCCAG
  TGGGCTCACTCGAAAGCAGAGCCCCTTTTCATGATGTGGACATAGCAGCGCACCTGTGAT
  CTGGACAGATTTTCCCACCTGTTTTCTCGACAGGGATTCCAGCAGGCATTATAAGGAGCC
  AGGTTCCAGGGATTGCCTTCTTTTTAAAACTGGGAAATCTTAGGACTCCGCTCCTTTTTC
  TTTAAACCTCCCCTTTTTTTTTTGCCCCCTGTGGGAGAAACTTGAGAAACTGTTTTCCCC
  TAAATATGGAACAGTTCCTCCGGAAGAAATTTTGCCCCTTTCCCTTAGAAACCCCCAGTT
  TTTTTCAACAGAGAGGGGCCCTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020365
• ORF Size: 1359 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020365.1, NP_065098.1
• RefSeq Size: 1602
• RefSeq ORF: 1359
• Locus ID: 8891
• Domains: NTP_transferase
• Gene Summary: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) encodes the longer isoform (1).