LZTFL1 (NM_020347) Human Untagged Clone

CAT#: SC113133

LZTFL1 (untagged)-Human leucine zipper transcription factor-like 1 (LZTFL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LZTFL1
• Synonyms: BBS17
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113133 sequence for NM_020347 edited (data generated by NextGen Sequencing)
  ATGGCAGAGTTGGGCCTAAATGAGCACCATCAAAATGAAGTTATTAATTATATGCGTTTT
  GCTCGTTCAAAGAGAGGCTTGAGACTCAAAACTGTAGATTCCTGCTTCCAAGACCTCAAG
  GAGAGCAGGCTGGTGGAGGACACCTTCACCATAGATGAAGTCTCTGAAGTCCTCAATGGA
  TTACAAGCTGTGGTTCATAGTGAGGTGGAATCTGAGCTCATCAACACTGCCTATACCAAT
  GTGTTACTTCTGCGACAGCTGTTTGCACAAGCTGAGAAGTGGTATCTTAAGCTACAGACA
  GACATCTCTGAACTTGAAAACCGAGAATTATTAGAACAAGTTGCAGAATTTGAAAAAGCA
  GAGATTACATCTTCAAACAAAAAGCCCATCTTAGATGTCACAAAGCCAAAACTTGCTCCA
  CTTAATGAAGGTGGAACAGCAGAACTCCTAAACAAGGAAATTTTAAGACTTCAAGAAGAG
  AATGAGAAATTGAAGTCAAGGTTGAAGACCATTGAAATACAGGCTACAAATGCACTGGAT
  GAAAAGTCAAAACTAGAAAAAGCACTGCAAGATTTACAGCTTGATCAAGGAAATCAAAAG
  GATTTTATAAAGGCCCAAGACTTAAGTAACTTAGAAAACACTGTCGCTGCCTTAAAGAGT
  GAGTTTCAGAAGACACTTAATGACAAGACAGAAAACCAGAAGTCACTGGAGGAGAATCTG
  GCGACAGCCAAGCACGATCTACTCAGGGTTCAGGAGCAGCTGCACATGGCTGAAAAGGAA
  TTAGAAAAGAAATTTCAGCAAACAGCAGCTTATCGAAACATGAAAGAGATTCTTACCAAG
  AAGAATGACCAAATCAAAGATCTGAGGAAAAGACTGGCACAATATGAACCTGAAGATTAA
  
  Clone variation with respect to NM_020347.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020347 unedited
  NCCGTTCAGATTTTGTATACGACTCACTATAGGGNNCGGCCGCGCAATTCGGCACGAGGA
  TTTTCTGTGGTCCAACTACCCTCGGCGATCCCAGGCTTGGCGGGGCACCGCCTGGCCTCT
  CCCGTTCCTTTAGGCTGCCGCCGCTGCCTGCCGCCATGGCAGAGTTGGGCCTAAATGAGC
  ACCATCAAAATGAAGTTATTAATTATATGCGTTTTGCTCGTTCAAAGAGAGGCTTGAGAC
  TCAAAACTGTAGATTCCTGCTTCCAAGACCTCAAGGAGAGCAGGCTGGTGGAGGACACCT
  TCACCATAGATGAAGTCTCTGAAGTCCTCAATGGATTACAAGCTGTGGTTCATAGTGAGG
  TGGAATCTGAGCTCATCAACACTGCCTATACCAATGTGTTACTTCTGCGACAGCTGTTTG
  CACAAGCTGAGAAGTGGTATCTTAAGCTACAGACAGACATCTCTGAACTTGAAAACCGAG
  AATTATTAGAACAAGTTGCAGAATTTGAAAAAGCAGAGATTACATCTTCAAACAAAAAGC
  CCATCTTAGATGTCACAAAGCCAAAACTTGCTCCACTTAATGAAGGTGGAACAGCAGAAC
  TCCTAAACAAGGAAATTTTAAGACTTCAAGAAGAGAATGAGAAATTGAAGTCAAGGTTGA
  AGACCATTGAAATACAGGCTACAAATGCACTGGATGAAAAGTCAAAACTAGAAAAAGCAC
  TGCAAGATTTACAGCTTGATCAAGGAAATCAAAAGGATTNTATAAAGGGCCCAAGACTTT
  AAGTACTTAGAAAACACTGTCGCTGCCTTAAAGNAGTGAGTTCAGAAGACACTTNTATGA
  CAGACAGAAAACCGAAGTCACTGGNAGNAGAATCTGGCGACAGCCAAGCCGATCTACTCA
  GGGGTCAGGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020347 unedited
  TGGCACTTCCAGGGCCGGNATAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCT
  GTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTT
  TAAAAATAAAGAGACATATTTATTTGTAATAACTCTCTTTTTTTGGTAATAACTATCTTT
  AACAATGCTATTATTTATTTTTACCCATGGGGAATGCATAAGTACAAACATTGTTAGCTT
  ATTTAACATTTATTAAAAATACAGACTCTTTATACTAATGCAGAAGGATAAGCCTCTTCT
  TCCCACTCTAAAAATCTCTTCTTTGCTGTAAAGAATTCTCAGTGCATGTGAGCTAAGACT
  CTGGAGCACTCAGTAGAGAGGTGTGTGGGATGACCAGACAGAATCACTAGGTTTTCTCTG
  TTTTCAACTAGCTGAAAATAGGAACTCTAGTTCTAAATATTCAAAGTCTAAATATTAGAA
  AAATAAGGAGAGGGGATATGACAAAATGCTTTTCAAAATACATGCCTGAGGTGAGACTGC
  TTGTATGTTTGCATGTGGTAGCTTCCAGAGGAAATCTTCAGTTTTAATCTTCAGGTTCAT
  ATTGTGCCAGTCTTTTCCTCAGATCTTTGATTTGGTCATTCTTCTTGGTAGAATCTCTTT
  CATGTTTCGATAAGCTGCTGTTTGCTGAAATTTCTTTTCTAATTCCTTTTCAGCCATGTG
  CAGCTGCTCCTGAACCCTGAATAGATCGTGCTTGGCTGTCGCAGATTTCCTCCANGACTT
  CTGGTTTCTGTCTTGCATTAAGGGTCTCTGAAACNACTCTTAAGCAGCGACAGTGTTCTA
  AGTACTTAGTCTTGGGCTTATAAATC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020347
• ORF Size: 900 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020347.2, NP_065080.1
• RefSeq Size: 3398
• RefSeq ORF: 900
• Locus ID: 54585
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.