PAK6 (NM_020168) Human Untagged Clone

CAT#: SC113203

PAK6 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1


  "NM_020168" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PAK6
Synonyms PAK5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC113203 sequence for NM_020168 edited (data generated by NextGen Sequencing)
ATGTTCCGCAAGAAAAAGAAGAAACGCCCTGAGATCTCAGCGCCACAGAACTTCCAGCAC
CGTGTCCACACCTCCTTCGACCCCAAAGAAGGCAAGTTTGTGGGCCTCCCCCCACAATGG
CAGAACATCCTGGACACACTGCGGCGCCCCAAGCCCGTGGTGGACCCTTCGCGAATCACA
CGGGTGCAGCTCCAGCCCATGAAGACAGTGGTGCGGGGCAGCGCGATGCCTGTGGATGGC
TACATCTCAGGGCTGCTCAACGACATCCAGAAGTTGTCAGTCATCAGCTCCAACACCCTG
CGTGGCCGCAGCCCCACCAGCCGGCGGCGGGCACAGTCCCTGGGGCTGCTGGGGGATGAG
CACTGGGCCACCGACCCAGACATGTACCTCCAGAGCCCCCAGTCTGAGCGCACTGACCCC
CACGGCCTCTACCTCAGCTGCAACGGGGGCACACCAGCAGGCCACAAGCAGATGCCGTGG
CCCGAGCCACAGAGCCCACGGGTCCTGCCCAATGGGCTGGCTGCAAAGGCACAGTCCCTG
GGCCCCGCCGAGTTTCAGGGTGCCTCGCAGCGCTGTCTGCAGCTGGGTGCCTGCCTGCAG
AGCTCCCCACCAGGAGCCTCGCCCCCCACGGGCACCAATAGGCATGGAATGAAGGCTGCC
AAGCATGGCTCTGAGGAGGCCCGGCCACAGTCCTGCCTGGTGGGCTCAGCCACAGGCAGG
CCAGGTGGGGAAGGCAGCCCTAGCCCTAAGACCCGGGAGAGCAGCCTGAAGCGCAGGCTA
TTCCGAAGCATGTTCCTGTCCACTGCTGCCACAGCCCCTCCAAGCAGCAGCAAGCCAGGC
CCTCCACCACAGAGCAAGCCCAACTCCTCTTTCCGACCGCCGCAGAAAGACAACCCCCCA
AGCCTGGTGGCCAAGGCCCAGTCCTTGCCCTCGGACCAGCCGGTGGGGACCTTCAGCCCT
CTGACCACTTCGGATACCAGCAGCCCCCAGAAGTCCCTCCGCACAGCCCCGGCCACAGGC
CAGCTTCCAGGCCGGTCTTCCCCAGCGGGATCCCCCCGCACCTGGCACGCCCAGATCAGC
ACCAGCAACCTGTACCTGCCCCAGGACCCCACGGTTGCCAAGGGTGCCCTGGCTGGTGAG
GACACAGGTGTTGTGACACATGAGCAGTTCAAGGCTGCGCTCAGGATGGTGGTGGACCAG
GGTGACCCCCGGCTGCTGCTGGACAGCTACGTGAAGATTGGCGAGGGCTCCACCGGCATC
GTCTGCTTGGCCCGGGAGAAGCACTCGGGCCGCCAGGTGGCCGTCAAGATGATGGACCTC
AGGAAGCAGCAGCGCAGGGAGCTGCTCTTCAACGAGGTGGTGATCATGCGGGACTACCAG
CACTTCAACGTGGTGGAGATGTACAAGAGCTACCTGGTGGGCGAGGAGCTGTGGGTGCTC
ATGGAGTTCCTGCAGGGAGGAGCCCTCACAGACATCGTCTCCCAAGTCAGGCTGAATGAG
GAGCAGATTGCCACTGTGTGTGAGGCTGTGCTGCAGGCCCTGGCCTACCTGCATGCTCAG
GGTGTCATCCACCGGGACATCAAGAGTGACTCCATCCTGCTGACCCTCGATGGCAGGGTG
AAGCTCTCGGACTTCGGATTCTGTGCTCAGATCAGCAAAGACGTCCCTAAGAGGAAGTCC
CTGGTGGGAACCCCCTACTGGATGGCTCCTGAAGTGATCTCCAGGTCTTTGTATGCCACT
GAGGTGGATATCTGGTCTCTGGGCATCATGGTGATTGAGATGGTAGATGGGGAGCCACCG
TACTTCAGTGACTCCCCAGTGCAAGCCATGAAGAGGCTCCGGGACAGCCCCCCACCCAAG
CTGAAAAACTCTCACAAGGTCTCCCCAGTGCTGCGAGACTTCCTGGAGCGGATGCTGGTG
CGGGACCCCCAAGAGAGAGCCACAGCCCAGGAGCTCCTAGACCACCCCTTCCTGCTGCAG
ACAGGGCTACCTGAGTGCCTGGTGCCCCTGATCCAGCTCTACCGAAAGCAGACCTCCACC
TGCTGA

Clone variation with respect to NM_020168.4
249 g=>a
>OriGene 5' read for NM_020168 unedited
CACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCATCTGATTATTT
TGGGAGCTGGAAACTTGGAGCTGCACCTGAGTCCCGCCCCTTCTAGCTCTCCCCTCCCTA
CCTTGGGCTCCAGGAAGATGGGACTTGCTGTGAGTCTGCTGCCACCCCCTAAAGATATGG
AAGACGCTGTGGGGGCCAGAAGTGCCCGGGGGGCTGTGGCAGCAGGCAGAGTGCAATAGC
AGATATGGTGGTCAGGCTGCCCGTGTGTGTCCTCTGGAGGTGTTGGGACAGAAGGGCAGT
CTTGTCCGAGCTGACTGGAGTCCTCCCGGGCTGGCTCTGAACTCATCTCCCACGGGGATG
TTTCGGTAAAGGAGTGGCTTCTGGGGTCGGAGTGGCATTTGGAGAGCGAGGCTGGATTGG
CTTANGCTGGCCTGGGCAGGGAGTGCCGCTTCCTGGGCTAGAGACAAGCACCAGCCTGCA
GTGGAGAACGCAGGACCCCGCTGCCCAGAAGGAGCAGCCACGGCCTGCGGAGGACTGGCC
CAGCAAGGTCCCAGGTCTTCCCTCTCCTCAGCGCCTAAGAGAGAGGCCCAGTGCGGGTGA
GGAGTCGCGAGGAAGAGGCGGAAGGCGCCGGAAGGCACCATGTTCCGCAAGAAAAAGAAG
AAACGCCCTGAGATCTCAGCGCCACAGAACTTCCAGCACCGTGTCCACACCTCCTTCGAC
CCCAAAGAAGGCAAGTTTGTGGGCCTCCCCCCACAATGGCAGAACATCCTGGACACACTG
CGGCGCCCCAAGCCGTGGTGGACCCTTCGCGATCACACGGGTGCAGCTCCAGCCCATGAA
GACAGTGGTGCGGNGCANCGCGATGCCTGTGGATGGCTACATCTCAGGGCTGCTCACGAC
TNCCAGAAGTGTCAGTCATCAGCTCACACCCTGCGTGGCCGCAGC
>OriGene 3' read for NM_020168 unedited
NTTTTTTGACTCTGCCCCGGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTT
TGGCTTTGAACACTCAATTTAATTTAAAACAGGCACAAGTGCAAACAATTCACAAAAATT
TCTAGGGAAGATGCTTTTGTTTTGAAAACTCTGACCCTTAAAAAAAAGTCCTTGCAATTT
CTTTGCCCCCAGGTAGGTCACTAGGGAGCAGAAGAATCTAAAAATATTATCTAGATAGAA
AGGGTCCAGACACCTGAAGTTCTTTCCTGGAATTCCATCTCACAGCAGCCCTGAAGTGGG
GCAGGGCCGAGGAGGACAAGGAGACAGCAGTCTGTGGAGGCAGCTGGGGCAGATGGTTTG
CACACATGGATGCCTGTGACCTTGACATGATGGAAACCCGGAGGTGGTTCGCCTTCTCTC
CCAGATAGGGTTCTGAAGAGAACAATGGGTCCCTGATGACCTGGCTATTGAGATAAACTT
GACAGGTAACACAGCCGCCAATCCTTACATTCCTGTCTCTGGCCCTCACGATGCACAGTA
CAGGAGAAGCTCAAAACCCTCCTGAGCCTCCAGGAGTGCTAGACTTACCATGGACCACTC
CACTGGCCACGTACACACCGGAGTGGCAGAGGCGGCAACCCCGCTCAACAAAGCCGGTTC
CTTTATGCCAATACTTATTGGCCAAAACGGGCCCTTCTCTCCGAAACCGGTTGCGGGCGA
CCCTGCAGAGACCCGGGTTGTTTTGGGGGGTTTTCTTTCCCTTACAGCTCTTTACTACCC
CCCCACCCCCCCCTACCTTGTCTCTCTTTTCGCAACCGCCCACCCCTTTTCCCCCCCTCC
CTCTCCTTCCCCCTCTCCCCAAAATGCGCCCCCCCTCCCCTCCCTCCCCTCCCTTCCTGT
CTTCTCCCCCCCCACCCCCGCCG
Restriction Sites NotI-NotI     
ACCN NM_020168
ORF Size 2046 bp
Insert Size 4470
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_020168.3, NP_064553.1
RefSeq Size 3889
RefSeq ORF 2046
Locus ID 56924
Domains PBD, pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
Gene Summary This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 4 encode the same isoform (1).

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