PBK (NM_018492) Human Untagged Clone

CAT#: SC113461

PBK (untagged)-Human PDZ binding kinase (PBK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PBK
• Synonyms: CT84; HEL164; Nori-3; SPK; TOPK
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_018492 edited
  ATGGAAGGGATCAGTAATTTCAAGACACCAAGCAAATTATCAGAAAAAAAGAAATCTGTA
  TTATGTTCAACTCCAACTATAAATATCCCGGCCTCTCCGTTTATGCAGAAGCTTGGCTTT
  GGTACTGGGGTAAATGTGTACCTAATGAAAAGATCTCCAAGAGGTTTGTCTCATTCTCCT
  TGGGCTGTAAAAAAGATTAATCCTATATGTAATGATCATTATCGAAGTGTGTATCAAAAG
  AGACTAATGGATGAAGCTAAGATTTTGAAAAGCCTTCATCATCCAAACATTGTTGGTTAT
  CGTGCTTTTACTGAAGCCAGTGATGGCAGTCTGTGTCTTGCTATGGAATATGGAGGTGAA
  AAGTCTCTAAATGACTTAATAGAAGAACGATATAAAGCCAGCCAAGATCCTTTTCCAGCA
  GCCATAATTTTAAAAGTTGCTTTGAATATGGCAAGAGGGTTAAAGTATCTGCACCAAGAA
  AAGAAACTGCTTCATGGAGACATAAAGTCTTCAAATGTTGTAATTAAAGGCGATTTTGAA
  ACAATTAAAATCTGTGATGTAGGAGTCTCTCTACCACTGGATGAAAATATGACTGTGACT
  GACCCTGAGGCTTGTTACATTGGCACAGAGCCATGGAAACCCAAAGAAGCTGTGGAGGAG
  AATGGTGTTATTACTGACAAGGCAGACATATTTGCCTTTGGCCTTACTTTGTGGGAAATG
  ATGACTTTATCGATTCCACACATTAATCTTTCAAATGATGATGATGATGAAGATAAAACT
  TTTGATGAAAGTGATTTTGATGATGAAGCATACTATGCAGCCTTGGGAACTAGGCCACCT
  ATTAATATGGAAGAACTGGATGAATCATACCAGAAAGTAATTGAACTCTTCTCTGTATGC
  ACTAATGAAGACCCTAAAGATCGTCCTTCTGCTGCACACATTGTTGAAGCTCTGGAAACA
  GATGTCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018492 unedited
  NGGCGTGTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGATGT
  GTTGGTGCTAGAGGCAGCTGCAGGGTCTCGCTGGGGGCCGCTCGGGACCAATTTTGAAGA
  GGTACTTGGCCACGACTTATTTTCACCTCCGACCTTTCCTTCCAGGCGGTGAGACTCTGG
  ACTGAGAGTGGCTTTCACAATGGAAGGGATCAGTAATTTCAAGACACCAAGCAAATTATC
  AGAAAAAAAGAAATCTGTATTATGTTCAACTCCAACTATAAATATCCCGGCCTCTCCGTT
  TATGCAGAAGCTTGGCTTTGGTACTGGGGTAAATGTGTACCTAATGAAAAGATCTCCAAG
  AGGTTTGTCTCATTCTCCTTGGGCTGTAAAAAAGATTAATCCTATATGTAATGATCATTA
  TCGAAGTGTGTATCAAAAGAGACTAATGGATGAAGCTAAGATTTTGAAAAGCCTTCATCA
  TCCAAACATTGTTGGTTATCGTGCTTTTACTGAAGCCAGTGATGGCAGTCTGTGTCTTGC
  TATGGAATATGGAGGTGAAAAGTCTCTAAATGACTTAATAGAAGAACGATATAAAGCCAG
  CCAAGATCCTTTTCCAGCAGCCATAATTTTAAAAGTTGCTTTGAATATGGCAAGAGGGTT
  AAAGTATCTGCACCAAGAAAAGAAACTGCTTCATGGAGACATAAAGTCTTCAAATGTTGT
  AATTAAAGGCGATTTTGAAACAATTAAAATCTGTGATGTANGAGTCTCTCTACCACTGGA
  TGAAAATATGACTGTGACTGACCCTGAGGCTTGTTACATTGGCACAGAGCCATGGAAACC
  CAAGAAGCTGTGGNAGAGAAATGGTGTTATTACTGACAGGNCAGACATATTTGCCTTTGG
  CCTTTACTTGTGGGAAATGATGACTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018492 unedited
  TGGACCGGCGGCCGCATTCTTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTA
  CCCAAGTGCCCTTTATTCTTTATCATCCTATTTGAGTTTTATTGTTTTTACACAGCTGGG
  AAATGCTTAAGGTACAAATTAATAAATTTTAAACTCAGTATGGAAAATACCTTTAATAAA
  TTAAAGCAAAAACCAAAGAAAGATCTGAGGAGATCCAAGAGATCAAGACAATCTGTCACC
  AGAGTCTGAAGTATCCAAGGAGCTACTCTTTTTGAGGCATATTCTCCTCAGCTTCCAGTT
  ATCATTTGATAAACACATCAGCAAAAGGTTCAGGGTTTTAAACAAATGTACACTTTATTT
  TGTACTGTACAAAGGGCTAATGCCAGTACATCCATTAAAATATAGAATATTTAAGAAAGA
  TCCATTCATAAAAGTACGGGTCATTCAATTTAATGTTACAGCTTACAGCGTTTTACCTGC
  TAGGGTTTTAAGTCAGCCTGACCCGTATTACAGCCCTTATGTACTCTAGTCTCTAAAACT
  TTACAGACAACCCAGTACACCCGCACGGGCTTATAGCCAATATAAGCCCATTTCCTATTA
  CAAATAGCCCCCCATACGTTAACAACCACCCATGGCCCTGCAATCTGCTCCTCCAACAGT
  CTACTACCTCCTGACAGTCACTATGTAACCACCTGGGGAACAAACAGTTATTCACGGTCG
  GCACACTACCCCCGCCCATGCATCCTATGACTTGTGCGTACCCGAGCCCGAACACTGTGT
  GGCATATAAAAGGAAGACCTCTTAGGGCGTTCATCAATCGTTACCGAATACCGTTCAAGT
  GCCTTCCGGTCCGATTGATCCCCCGTTCTGATCCTACTAGGGGCGCACCCGCCATGCCGC
  CCATATCCCCTCCTTCTCCGTTTTTTCTTACGGGTTCGTCCCCGATCCCGTCGCGACTTG
  GAAAACTAATGGGGCGACCCGTGCCGTGCTCTTGTCATCGCATCTGCCTATTGCTACTCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018492
• ORF Size: 969 bp
• Insert Size: 1850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_018492.2, NP_060962.2
• RefSeq Size: 1899
• RefSeq ORF: 969
• Locus ID: 55872
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longest transcript, and encodes the shorter isoform (1). Variants 1 and 3 encode the same isoform (1).