CYP39A1 (NM_016593) Human Untagged Clone

CAT#: SC114150

CYP39A1 (untagged)-Human cytochrome P450, family 39, subfamily A, polypeptide 1 (CYP39A1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP39A1
• Synonyms: cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450, family 39, subfamily a, polypeptide 1; oxysterol 7-alpha-hydroxylase; oxysterol 7alpha-hydroxylase
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114150 sequence for NM_016593 edited (data generated by NextGen Sequencing)
  ATGGAACTAATTTCCCCAACAGTGATTATAATCCTGGGTTGCCTTGCTCTGTTCTTACTC
  CTTCAGCGGAAGAATTTGCGTAGACCCCCGTGCATCAAGGGCTGGATTCCTTGGATTGGA
  GTTGGATTTGAGTTTGGGAAAGCCCCTCTAGAATTTATAGAGAAAGCAAGAATCAAGTAT
  GGACCAATATTTACAGTCTTTGCTATGGGAAACCGAATGACCTTTGTTACTGAAGAAGAA
  GGAATTAATGTGTTTCTAAAATCCAAAAAAGTAGATTTTGAACTAGCAGTGCAAAATATC
  GTTTATCGTACAGCATCAATTCCAAAGAATGTCTTTTTAGCACTGCATGAAAAACTCTAT
  ATTATGTTGAAAGGGAAAATGGGGACTGTCAATCTCCATCAGTTTACTGGGCAACTGACT
  GAAGAATTACATGAACAACTGGAGAATTTAGGCACTCATGGGACAATGGACCTGAACAAC
  TTAGTAAGACATCTCCTTTATCCAGTCACAGTGAATATGCTCTTTAATAAAAGTTTGTTT
  TCCACAAACAAGAAAAAAATCAAGGAGTTCCATCAGTATTTTCAAGTTTATGATGAAGAT
  TTTGAGTATGGGTCCCAGTTGCCAGAGTGTCTTCTAAGAAACTGGTCAAAATCCAAAAAG
  TGGTTCCTGGAACTGTTTGAGAAAAACATTCCAGATATAAAAGCATGTAAATCTGCAAAA
  GATAATTCCATGACATTATTGCAAGCTACGCTGGATATTGTAGAGACGGAAACAAGTAAG
  GAAAACTCACCCAATTATGGGCTCTTACTGCTTTGGGCTTCTCTGTCTAATGCTGTTCCT
  GTTGCATTTTGGACACTTGCATACGTCCTTTCTCATCCTGATATCCACAAGGCCATTATG
  GAAGGCATATCTTCTGTGTTTGGCAAAGCAGGCAAAGATAAGATTAAAGTGTCTGAGGAT
  GACCTGGAGAATCTCCTTCTAATTAAATGGTGTGTTTTGGAAACCATTCGTTTAAAAGCT
  CCTGGTGTCATTACTAGAAAAGTGGTGAAGCCTGTGGAAATTTTGAATTACATCATTCCT
  TCTGGTGACTTGTTGATGTTGTCTCCATTTTGGCTGCATAGAAATCCAAAGTATTTTCCT
  GAGCCTGAATTGTTCAAACCTGAACGTTGGAAAAAGGCAAATTTAGAGAAGCACTCTTTC
  TTGGACTGCTTCATGGCATTTGGAAGCGGGAAGTTCCAGTGTCCTGCAAGGTGGTTTGCT
  CTGTTAGAGGTTCAGATGTGTATTATTTTAATACTTTATAAATATGACTGTAGTCTTCTG
  GACCCATTACCCAAACAGAGTTATCTCCATTTGGTGGGTGTCCCCCAGCCGGAAGGGCAA
  TGCCGAATTGAATATAAACAAAGAATATGA
  
  Clone variation with respect to NM_016593.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016593 unedited
  CACATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCAAAATTGCAGCA
  GAAGGTTGGGAGTCCCGACAGNNGTTCCGTAGCCCACAGNAAAAGAAGCAAGGGACGGCA
  GGACTGTTTCACACTTTTCTGCTTCTGGAAGGTGCTGGACAAAAACATGGAACTAATTTC
  CCCAACAGTGATTATAATCCTGGGTTGCCTTGCTCTGTTCTTACTCCTTCAGCGGAAGAA
  TTTGCGTAGACCCCCGTGCATCAAGGGCTGGATTCCTTGGATTGGAGTTGGATTTGAGTT
  TGGGAAAGCCCCTCTAGAATTTATAGAGAAAGCAAGAATCAAGTATGGACCAATATTTAC
  AGTCTTTGCTATGGGAAACCGAATGACCTTTGTTACTGAAGAAGAAGGAATTAATGTGTT
  TCTAAAATCCAAAAAAGTAGATTTTGAACTAGCAGTGCAAAATATCGTTTATCGTACAGC
  ATCAATTCCAAAGAATGTCTTTTTAGCACTGCATGAAAAACTCTATATTATGTTGAAAGG
  GAAAATGGGGACTGTCAATCTCCATCAGTTTACTGGGCAACTGACTGAAGAATTACATGA
  ACAACTGGAGAATTTAGGCACTCATGGGACAATGGACCTGAACAACTTAGTAAGACATCT
  CCTTTATCCAGTCACAGTGAATATGCTCTNTAATAAAAGTTTGTTTTCCACAAACAAGAA
  AAAAATCAAGGAGTTCCATCAGTATTTTCAAGTTTATGATAGAGANTTTGAGTATGGGTC
  CCAGTTGCCAGAGTGTCTTCTAAGAACTGGTCAAAATCCAAAAGTGGTTCCTGGAACTGT
  TTGAGAAAACATTCCANAATAAAAGCTGTAAATCTGCAAAGATAATCCATGACATATTGC
  AGCTACGCTGGAATTGTAGAGACGGAAACAAGTAGGAAACTCCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016593 unedited
  CTATGAACCGCGNGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTCCAACCAACATACATTTATTGAATATACTCTGTAAAAAAGGGGCAATCCTGACC
  ATAATAAAGGGTAAAAATGAATGTAAAACACCTTTCCTGTCCTCACAGGTCTCAAAAAAC
  TACCATTTTATTACTTTTACCATTAAATCCGTTTACAATAAAAAATTATGTTAATAAACC
  CTAGGAGTTCCAATTGCTAGTTGAAAATCCCCTCAAAAAAAATAAAAAATTTGTAAAAAT
  AATTATTAAATTTTAAAAATCTAACCCTTTTAAACTTTTCAAAATAAAAATTTAAGTATG
  CTGCCTTCACAGGGAATTTAATGGGATAAAATTTTCATTCAAAGGACATTATTTCTATTT
  AAGGTTTTAATACAGTTATGCATGAAATCAAATTCCAACTTCTTAAAAAATGGGGAGTTT
  TTTTGGATCATTTGATCATTTCCTATAAACCATGTATTCCGGTCTCTATATTACTGAAAG
  TGATGTTAAATTCTTGGTCTACTGTTGAAAATACCAAACACATGCACCATTTGAATGTGT
  TCTTGAACTAAGCCCTAAAACAAAGTGAACCAGTGTGTTTTTGTAAAGCTCAGGTCTAGG
  TGCTGCCAGGGGGGGTAGTGCCACTCCTCCAGAAGGCCCTGGTCCTTGTGAGGCCCAACA
  GATGTCATATTCTTTGTTTATATTCAATTCGGCATTGCCCCTTCGGCTGGGGGACACCCA
  CCAAATGGAAATAACTCTGTTTGGGTAATGGGCCCAAACACTCCGTCATATTTATAAGGT
  TTAAAATAATCACCATCTGACCTCTAACAGAGAAACCCCCTTGCAGACACTGAACCTCCC
  GCTTCCAAAGCCATGAACAGNCCAGAAAAAGGCTTCTTAATTGCCTTTTCCAACCTAAGT
  NTGAAACATCAGCCACGGAAATCTCTGGATTCTTGCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016593
• ORF Size: 1410 bp
• Insert Size: 2140
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016593.3, NP_057677.2
• RefSeq Size: 2288
• RefSeq ORF: 1410
• Locus ID: 51302
• Domains: p450
• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Primary bile acid biosynthesis
• Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.