CYP39A1 (NM_016593) Human Untagged Clone

CAT#: SC320883

CYP39A1 (untagged)-Human cytochrome P450, family 39, subfamily A, polypeptide 1 (CYP39A1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP39A1
• Synonyms: cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450, family 39, subfamily a, polypeptide 1; oxysterol 7-alpha-hydroxylase; oxysterol 7alpha-hydroxylase
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016593.3 GGGGGAAGTGGAGGTGGGAGGGAGCGACAATGGAAAAATCACCTGAAAACTGGGACAGAG
  GAAGGAAGCTACAGTTACGAAGGAGAGCTGCAAAAGTTGCAGCAGAAAGGTTGGGAGTCC
  CGACAGGTTCCGTAGCCCACAGAAAAGAAGCAAGGGACGGCAGGACTGTTTCACACTTTT
  CTGCTTCTGGAAGGTGCTGGACAAAAACATGGAACTAATTTCCCCAACAGTGATTATAAT
  CCTGGGTTGCCTTGCTCTGTTCTTACTCCTTCAGCCGAAGAATTTGCGTAGACCCCCGTG
  CATCAAGGGCTGGATTCCTTGGATTGGAGTTGGATTTGAGTTTGGGAAAGCCCCTCTAGA
  ATTTATAGAGAAAGCAAGAATCAAGTATGGACCAATATTTACAGTCTTTGCTATGGGAAA
  CCGAATGACCTTTGTTACTGAAGAAGAAGGAATTAATGTGTTTCTAAAATCCAAAAAAGT
  AGATTTTGAACTAGCAGTGCAAAATATCGTTTATCGTACAGCATCAATTCCAAAGAATGT
  CTTTTTAGCACTGCATGAAAAACTCTATATTATGTTGAAAGGGAAAATGGGGACTGTCAA
  TCTCCATCAGTTTACTGGGCAACTGACTGAAGAATTACATGAACAACTGGAGAATTTAGG
  CACTCATGGGACAATGGACCTGAACAACTTAGTAAGACATCTCCTTTATCCAGTCACAGT
  GAATATGCTCTTTAATAAAAGTTTGTTTTCCACAAACAAGAAAAAAATCAAGGAGTTCCA
  TCAGTATTTTCAAGTTTATGATGAAGATTTTGAGTATGGGTCCCAGTTGCCAGAGTGTCT
  TCTAAGAAACTGGTCAAAATCCAAAAAGTGGTTCCTGGAACTGTTTGAGAAAAACATTCC
  AGATATAAAAGCATGTAAATCTGCAAAAGATAATTCCATGACATTATTGCAAGCTACGCT
  GGATATTGTAGAGACGGAAACAAGTAAGGAAAACTCACCCAATTATGGGCTCTTACTGCT
  TTGGGCTTCTCTGTCTAATGCTGTTCCTGTTGCATTTTGGACACTTGCACACGTCCTTTC
  TCATCCTGATATCCACAAGGCCATTATGGAAGGCATATCTTCTGTGTTTGGCAAAGCAGG
  CAAAGATAAGATTAAAGTGTCTGAGGATGACCTGGAGAATCTCCTTCTAATTAAATGGTG
  TGTTTTGGAAACCATTCGTTTAAAAGCTCCTGGTGTCATTACTAGAAAAGTGGTGAAGCC
  TGTGGAAATTTTGAATTACATCATTCCTTCTGGTGACTTGTTGATGTTGTCTCCATTTTG
  GCTGCATAGAAATCCAAAGTATTTTCCTGAGCCTGAATTGTTCAAACCTGAACGTTGGAA
  AAAGGCAAATTTAGAGAAGCACTCTTTCTTGGACTGCTTCATGGCATTTGGAAGCGGGAA
  GTTCCAGTGTCCTGCAAGGTGGTTTGCTCTGTTAGAGGTTCAGATGTGTATTATTTTAAT
  ACTTTATAAATATGACTGTAGTCTTCTGGACCCATTACCCAAACAGAGTTATCTCCATTT
  GGTGGGTGTCCCCCAGCCGGAAGGGCAATGCCGAATTGAATATAAACAAAGAATATGACA
  TCTGTTGGGCCTCACAAGGACCAGGGCCTTCTGGAGGAGTGGCACTACCCCACCTGGCAG
  CACCTAGACCTGAGCTCTACAAAAACACACTGCTTCACTTTGTTTTAGGACTTAGTTCAA
  GAACACATTCAAATGGTGCATGTGTTTGGTATCTTCAACAGTAGACCAAGAATCTAACAT
  CACTCTCAGTAATATAGAGACCGGAATACATGGTTTATAGGAAATGATCAAATGATCCAA
  AAAAACTCCACATTTTTTAAGAAGTTGGAATTTGATTTCATGCATAACTGTATTAAAACA
  TTAAATAGAAATAATGTCATTTGAATGAAAATCTTATCACATTAAATTCACTGTGAAGGC
  AGCATACTTAAATTTTTATTTTGAAAAGTCTAAAAGGCTTAGATTTTTAAAATTTAATAA
  TTATTTCTACAAATTTTCTATTTTTCTTGAGGTGATTCTCAACTAGCAATTGGAACTCCT
  AGGCTCTATTAACATAATTCTTTATTGTAAACGTATCTAATGCTAAAAGTAATAAAATGG
  TAGTTTTCTGAGACCTGCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016593.3 unedited
  GCGATTGTATACGACTCCTATAGGGCGGCAGGGAAATTCGGCCATTACGGCCGGGGGAAG
  TGGAGGTGGGAGGGAGCGACAATGGAAAAATCACCTGAAAACTGGGACAGAGGAAGGAAG
  CTACAGTTACGAAGGAGAGCTGCAAAAGTTGCAGCAGAAAGGTTGGGAGTCCCGACAGGT
  TCCGTAGCCCACAGAAAAGAAGCAAGGGACGGCAGGACTGTTTCACACTTTTCTGCTTCT
  GGAAGGTGCTGGACAAAAACATGGAACTAATTTCCCCAACAGTGATTATAATCCTGGGTT
  GCCTTGCTCTGTTCTTACTCCTTCAGCCGAAGAATTTGCGTAGACCCCCGTGCATCAAGG
  GCTGGATTCCTTGGATTGGAGTTGGATTTGAGTTTGGGAAAGCCCCTCTAGAATTTATAG
  AGAAAGCAAGAATCAAGTATGGACCAATATTTACAGTCTTTGCTATGGGAAACCGAATGA
  CCTTTGTTACTGAAGAAGAAGGAATTAATGTGTTTCTAAAATCCAAAAAAGTAGATTTTG
  AACTAGCAGTGCAAAATATCGTTTATCGTACAGCATCAATTCCAAAGAATGTCTTTTTAG
  CACTGCATGAAAAACTCTATATTATGTTGAAAGGGAAAATGGGGACTGTCAATCTCCATC
  AGTTTACTGGGCAACTGACTGAAGAATTACATGAACAACTGGAGAATTTAGGCACTCATG
  GGACAATGGACCTGACAACTTAGTAAGACATCTCCTTTATCCAGTCACAGTGAATATGCT
  CTTTATAAAAGTTTGTTTTCCACAAACAGAAAAAAATCAAGGAGTCATCAGTATTTTCAA
  GTTTATGATGAAGATTTTGAGTTATGGTCCCAGTTGCAGAGTGTTCTTCTAGAACCTGTT
  CAAATCAAAAGTGATCTGAACTGTTGAGAAACGTGCGATTAAGCATGTAATCTGCAAGAT
  ATTCCATGACATTATTGC
• Restriction Sites: Please inquire
• ACCN: NM_016593
• ORF Size: 1410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016593.3, NP_057677.2
• RefSeq Size: 2288
• RefSeq ORF: 1410
• Locus ID: 51302
• Domains: p450
• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Primary bile acid biosynthesis
• Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.