GTF2IRD1 (NM_016328) Human Untagged Clone

CAT#: SC114317

GTF2IRD1 (untagged)-Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GTF2IRD1
• Synonyms: BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016328, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTTGCTGGGTAAGCGCTGTGACGTCCCCACCAACGGCTGCGGACCCGACCGCTGGAACTCCGCGT
  TCACCCGCAAAGACGAGATCATCACCAGCCTCGTGTCTGCCTTAGACTCCATGTGCTCAGCGCTGTCCAA
  ACTGAACGCCGAGGTGGCCTGTGTCGCCGTGCACGATGAGAGCGCCTTTGTGGTGGGCACAGAGAAGGGG
  AGAATGTTCCTGAATGCCCGGAAGGAGCTACAGTCAGACTTCCTCAGGTTCTGCCGAGGGCCCCCGTGGA
  AGGATCCGGAGGCAGAGCACCCCAAGAAGGTGCAGCGGGGCGAGGGTGGAGGCCGTAGCCTCCCTCGGTC
  CTCCCTGGAACATGGCTCAGATGTGTACCTTCTGCGGAAGATGGTAGAGGAGGTGTTTGATGTTCTTTAT
  AGCGAGGCCCTGGGAAGGGCCAGTGTGGTGCCACTGCCCTATGAGAGGCTGCTCAGGGAGCCAGGGCTGC
  TGGCCGTGCAGGGGCTGCCCGAAGGCCTGGCCTTCCGAAGGCCAGCCGAGTATGACCCCAAGGCCCTCAT
  GGCCATCCTGGAACACAGCCACCGCATCCGCTTCAAGCTCAAGAGGCCACTTGAGGATGGCGGGCGGGAC
  TCGAAGGCCCTGGTGGAGCTGAACGGTGTCTCCCTGATTCCCAAGGGGTCACGGGACTGTGGCCTGCATG
  GCCAGGCCCCCAAGGTGCCACCCCAGGACCTGCCCCCAACCGCCACCTCCTCCTCCATGGCCAGCTTCCT
  GTACAGCACGGCGCTCCCCAACCACGCCATCCGAGAGCTCAAGCAGGAAGCACCTTCCTGCCCCCTTGCC
  CCCAGCGACCTGGGCCTGAGTCGGCCCATGCCAGAGCCCAAGGCCACCGGTGCCCAAGACTTCTCCGACT
  GTTGTGGACAGAAGCCCACTGGGCCTGGTGGGCCTCTCATCCAGAACGTCCATGCCTCCAAGCGCATTCT
  CTTCTCCATCGTCCATGACAAGTCAGAGAAGTGGGACGCCTTCATAAAGGAAACCGAGGACATCAACACG
  CTCCGGGAGTGTGTGCAGATCCTGTTTAACAGCAGATATGCGGAAGCCCTGGGCCTGGACCACATGGTCC
  CCGTGCCCTACCGGAAGATTGCCTGTGACCCGGAGGCTGTGGAGATCGTGGGCATCCCGGACAAGATCCC
  CTTCAAGCGCCCCTGCACTTATGGAGTCCCCAAGCTGAAGCGGATCCTGGAGGAGCGCCATAGTATCCAC
  TTCATCATTAAGAGGATGTTTGATGAGCGAATTTTCACAGGGAACAAGTTTACCAAAGACACCACGAAGC
  TGGAGCCAGCCAGCCCGCCAGAGGACACCTCTGCAGAGGTCTCTAGGGCCACCGTCCTTGACCTTGCTGG
  GAATGCTCGGTCAGACAAGGGCAGCATGTCTGAAGACTGTGGGCCAGGAACCTCCGGGGAGCTGGGCGGG
  CTGAGGCCGATCAAAATTGAGCCAGAGGATCTGGACATCATTCAGGTCACCGTCCCAGACCCCTCGCCAA
  CCTCTGAGGAAATGACAGACTCGATGCCTGGGCACCTGCCATCGGAGGATTCTGGTTATGGGATGGAGAT
  GCTGACAGACAAAGGTCTGAGTGAGGACGCGCGGCCCGAGGAGAGGCCCGTGGAGGACAGCCACGGTGAC
  GTGATCCGGCCCCTGCGGAAGCAGGTGGAGCTGCTCTTCAACACACGATACGCCAAGGCCATTGGCATCT
  CGGAGCCCGTCAAGGTGCCGTACTCCAAGTTTCTGATGCACCCGGAGGAGCTGTTTGTGGTGGGACTGCC
  TGAAGGCATCTCCCTCCGCAGGCCCAACTGCTTCGGGATCGCCAAGCTCCGGAAGATTCTGGAGGCCAGC
  AACAGCATCCAGTTTGTCATCAAGAGGCCCGAGCTGCTCACTGAGGGAGTCAAAGAGCCCATCATGGATA
  GTCAAGGAACTGCCTCCTCACTTGGCTTCTCTCCCCCTGCCCTGCCCCCAGAGAGGGATTCCGGGGACCC
  TCTGGTGGACGAGAGCCTGAAGAGACAGGGCTTTCAAGAAAATTATGACGCGAGGCTCTCACGGATCGAC
  ATCGCCAACACACTAAGGGAGCAGGTCCAGGACCTTTTCAATAAGAAATACGGGGAAGCCTTGGGCATCA
  AGTACCCGGTCCAGGTCCCCTACAAGCGGATCAAGAGTAACCCCGGCTCCGTGATCATCGAGGGGCTGCC
  CCCAGGAATCCCGTTCCGAAAGCCCTGTACCTTCGGCTCCCAGAACCTGGAGAGGATTCTTGCTGTGGCT
  GACAAGATCAAGTTCACAGTCACCAGGCCTTTCCAAGGACTCATCCCAAAGCCTGATGAAGATGACGCCA
  ACAGACTCGGGGAGAAGGTGATCCTGCGGGAGCAGGTGAAGGAACTCTTCAACGAGAAATACGGTGAGGC
  CCTGGGCCTGAACCGGCCGGTGCTGGTCCCTTATAAACTAATCCGGGACAGCCCAGACGCCGTGGAGGTC
  ACGGGTCTGCCTGATGACATCCCCTTCCGGAACCCCAACACGTACGACATCCACCGGCTGGAGAAGATCC
  TGAAGGCCCGAGAGCATGTCCGCATGGTCATCATTAACCAGCTCCAACCCTTTGCAGAAATCTGCAATGA
  TGCCAAGGTGCCAGCCAAAGACAGCAGCATTCCCAAGCGCAAGAGAAAGCGGGTCTCGGAAGGAAATTCC
  GTCTCCTCTTCCTCCTCGTCTTCCTCTTCCTCGTCCTCTAACCCGGATTCAGTGGCATCGGCCAACCAGA
  TCTCACTCGTGCAATGGCCAATGTACATGGTGGACTATGCCGGCCTGAACGTGCAGCTCCCGGGACCTCT
  TAATTACTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016328 unedited
  TTCGACATTGTATACGACTCATATAGGCGGCCGCGACATTCGCACGAGGCCCCCCCGCGC
  CCCCTCCCCGCGCCTCCCTCCCCGCCCTCGCCGCGCCGCCGTCCTCGCCTCCCTCTGCCT
  CTCCTTCCCCCATTCTCCCGGATTAATTAAGGAGGCAGCGGCAGGAGGCTGAGTCCTGGC
  CGCGGGCCGGGGCCGGGGCGCCGCTGGCAGGAGCGCTTGGGGATCCTCCAAGGCGACCAT
  GGCCTTGCTGGGTAAGCGCTGTGACGTCCCCACCAACGGCTGCGGACCCGACCGCTGGAA
  CTCCGCGTTCACCCGCAAAGACGAGATCATCACCAGCCTCGTGTCTGCCTTATACTCCAT
  GTGCTCAGCGCTGTCCAAACTGAACGCCGAGGTGGCCTGTGTCGCCGTGCACGATGAGAG
  CGCCTTTGTGGTGGGCACAGAGAAGGGGAGAATGTTCCTGAATGCCCGGAAGGAGCTACA
  GTCAGACTTCCTCAGGTTCTGCCGAGGGCCCCCGTGGAAGGATCCGGAGGCAGAGCACCC
  CAAGAAGGTGCAGCGGGGCGAGGGNTGGGATGGCCGTAGCCTCCCTCGGTCCTCCCTGGA
  ACATGGCTCATATGTGTACCTTCTGCGGAAGATGGAAGGAAGTGTGTTNGAGAGGTTCTT
  AATAGCGAGGCCTGGGGGAGGGCCAGTGTGGTGCCACTGCCCTATGAGAGGCTGCTCATG
  GAGCCAGGGCTGCTGGCCGTGCATGGGCTGCCCCGATAGCCTGGGCCTTCCGATGCCAGC
  CGAGTATGACCCCAAGCCCTCATGGCCATCCTGGGACACAGCCACCGCATCCGCTTCAAG
  CTCAAGAGCCACTTGAGGATGCCGGGCGGGACTCGAAGCCCTGGTGAGCTGNAACGTGTC
  TCCTGATCCCAAGGGTCACGGNACTGTGGCCTGCATGCCCGGCCCCCAGTGCCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016328 unedited
  GTCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACTTATTTAAAAAGGC
  CTTGGTGGCAGGAATATAGTGTAAAAATCATTGGAAAAACTAAAAGGCATCGATACATAT
  CCGAATATACATTTTGTACATAAATTACATTTCCTTTAGTCTTTCTGAGTGAGGTCCTGA
  TTCAGTACTGAGGTCTAGTAATTAAGAGGTCCCGGGAGCTGCACGTTCAGGCCGGCATAG
  TCCACCATGTACATTGGCCATTGCACGAGTGAGATCTGGTTGGCCGATGCCACTGAATCC
  GGGTTAGAGGACGAGGAAGAGGAAGACGAGGAGGAAGAGGAGACGGAATTTCCTTCCGAG
  ACCCGCTTTCTCTTGCGCTTGGGAATGCTGCTGTCTTTGGCTGGCACCTTGGCATCATTG
  CAGATTTCTGCAAAGGGTTGGAGCTGGTTAATGATGACCATGCGGACATGCTCTCGGGCC
  TTCAGGATCTTCTCCAGCCGGTGGATGTCGTACGTGTTGGGGTTCCGGAAGGGGATGTCA
  TCAGGCAGACCCGTGACCTCCACGGCGTCTGGGCTGTCCCGGATTAGTTTATAAGGGACC
  AGCACCGGCCGGTTCAGGCCCACGGCCTCACCGTATTTCTCGTTGAAGAGTTCCTTCACC
  TGCTCCCGAGGATCACCTTCCTCCCGAGTCTGTTGCCGTATTTTCATTAAGCTTTGGCAG
  AATCCTTGGAAAGCCTGCGACTGTAACCTGATCTGTCACCCCACCAAGACCCTTTCAGGT
  TTTGGACCCCAAGGCCAGCTTTTCCGCACGGATTCTGGGGGAAGCCCCCAGATCAGAACC
  CGGTTACCCCTGTCCGTTTTACGCACCTGACCGGCCCCTATCCCCCGTTCCCTTTTTTAT
  TCAAGGTCCCGCCGCCCCTCCGCCGTCATGTCATCCGTCACCCCTGTCAACCTTCTACCC
  CGTCCTGTTTTTCCCTCAGGTCCGCCCTTCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016328
• ORF Size: 2880 bp
• Insert Size: 3160
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_016328.1, NP_057412.1
• RefSeq Size: 3446
• RefSeq ORF: 2880
• Locus ID: 9569
• Domains: GTF2I
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Basal transcription factors
• Gene Summary: The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (1) uses alternate splice sites in the coding region, compared to variant 3. The encoded isoform (1) is shorter compared to isoform 3.