PRKAG2 (NM_016203) Human Untagged Clone

CAT#: SC114421

PRKAG2 (untagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRKAG2
• Synonyms: AAKG; AAKG2; CMH6; H91620p; WPWS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114421 sequence for NM_016203 edited (data generated by NextGen Sequencing)
  ATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCCCGGCGGGAGC
  GGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACATTCCGGACCTG
  AGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCT
  CGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTTCTCCAGAGGC
  CCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGACCAGCCCCGGC
  TCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGC
  ATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCAACTCCAACCCT
  GCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCTCCGGCCTCTCC
  TCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTAT
  AAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACA
  GGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCG
  ACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCC
  GGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGCAGTAGAAGACTCAGAAAGTGGTGTT
  TACATGCGATTCATGAGGTCACACAAGTGTTATGACATCGTTCCAACCAGTTCAAAGCTT
  GTTGTCTTTGATACTACATTACAAGTTAAAAAGGCCTTCTTTGCTTTGGTAGCCAACGGT
  GTCCGAGCAGCGCCACTGTGGGAGAGTAAAAAACAAAGTTTTGTAGGAATGCTAACAATT
  ACAGATTTCATAAATATACTACATAGATACTATAAATCACCTATGGTACAGATTTATGAA
  TTAGAGGAACATAAAATTGAAACATGGAGGGAGCTTTATTTACAAGAAACATTTAAGCCT
  TTAGTGAATATATCTCCAGATGCAAGCCTCTTCGATGCTGTATACTCCTTGATCAAAAAT
  AAAATCCACAGATTGCCCGTTATTGACCCTATCAGTGGGAATGCACTTTATATACTTACC
  CACAAAAGAATCCTCAAGTTCCTCCAGCTTTTTATGTCTGATATGCCAAAGCCTGCCTTC
  ATGAAGCAGAACCTGGATGAGCTTGGAATAGGAACGTACCACAACATTGCCTTCATACAT
  CCAGACACTCCCATCATCAAAGCCTTGAACATATTTGTGGAAAGACGAATATCAGCTCTG
  CCTGTTGTGGATGAGTCAGGAAAAGTTGTAGATATTTATTCCAAATTTGATGTAATTAAT
  CTTGCTGCTGAGAAAACATACAATAACCTAGATATCACGGTGACCCAGGCCCTTCAGCAC
  CGTTCACAGTATTTTGAAGGTGTTGTGAAGTGCAATAAGCTGGAAATACTGGAGACCATC
  GTGGACAGAATAGTAAGAGCTGAGGTCCATCGGCTGGTGGTGGTAAATGAAGCAGATAGT
  ATTGTGGGTATTATTTCCCTGTCGGACATTCTGCAAGCCCTGATCCTCACACCAGCAGGT
  GCCAAACAAAAGGAGACAGAAACGGAGTGA
  
  Clone variation with respect to NM_016203.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016203 unedited
  ATTTTGTTTACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGAGGAAGGACGCTTGA
  ATTCGGCGCTTCGGCGGCGGCGGCGGCCGCGCGAGTTCCCTGCTCACCCTCCCTCTCCGC
  GGAAGTCCCCACGAGGTGGCTTCAGGGTGTAACAGAGCGCGCGGCTCCAGTCCGAAGGCA
  GCGGCCGGGGGAGGGAAGGAGGGGACCGAACCCCCGAGGAGTTTCGCAGAATCAACTTCT
  GGTTAGAGTTATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCC
  CGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACAT
  TCCGGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAA
  GCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTT
  CTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGAC
  CAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTC
  CCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAGAGTCTTCCCCCAAC
  TCCAACCCTGCTACCTCGCCCGGGGGCATTAAGTTTTTTCTCCCGCTCCAGAAAACCTTC
  GGGCTCTTCTCCTCTCCGGCACCACCACCCAGTGACCAAGCAGCACACGTTTCCCCTGGA
  ATCCCTAAGCACGAGCCTCGACCGGTAAGAGATCGCATTTATGCCTCGGTTTCCCCCCGG
  ACACAGGGCAACAGTTTTGCCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016203 unedited
  CGGGGGACCTTTGGNNGATGGCAACTTNCCAGTTCCAGGNANAGCACTGGGGNAGGGTCA
  CAGGATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTC
  GAGTTTTTTTTTTTTTTTTTTCATGGATGTGGTGAAGTTTATTCCACCAAAAGATGTGTA
  AAAAAATTGCATGAAAGTAAAAATAAATAAAGCTGTTGTAAAGCAGCCTCGTTGACACGG
  TAGCCCAGAACAAAACACTTACGTGTAAAAGTGTCATTACAATTTTAAAGTAATTATTTA
  TATTCAAATTACAACTTTTTGACAAATCTAAAGAAAACAAACTGATTTGGTAAAAGGTTC
  AAAGACTTCCACATTCAAGCTCGGTGTTGTTTCACACGCGTGCGCCCCGGCTGCGGCGGT
  GACATATTGCTGTATTCGGACATAAGGCACTGTGATCTGAACATACCGTGCACTCACCTT
  ATGCCACATCACCTGTTCCATACCAGTGAATTCTTTGAAATGAAAAATAATGAAAACTTC
  AGGACACAGTGCACTTTAATGACATACAGCATTTAAAATCCTTCAGACAAAGGTCTGAAA
  ACAGTCTTTTAATGCAAGCCTGAATCTTCAAGCACATAAAATCTTTCTTTTTTAAGCTTA
  ATTTCAACATCACTGGAAGAAATACCTATTGTTAAAACCCTGATATACATTCTTAACCAC
  TTGCAACCCGTGGTCATGAGGCCAAACGTGGCCCAGAAACTTTTTTCAAATTCTCCTCCT
  AGGGCGTCTACATTTCCGGGGGGGCACCTCCGTTTCTGTCTCCTTTTGTTTGGCACCTGG
  TGGTGTGAGAATCAAGCCTTGCAAAATGTTCAAAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016203
• ORF Size: 1710 bp
• Insert Size: 2600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016203.2, NP_057287.2
• RefSeq Size: 2062
• RefSeq ORF: 1710
• Locus ID: 51422
• Domains: CBS
• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway
• Gene Summary: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (a, also referred to as PRKAG2-a).