PRKAG2 (NM_016203) Human Untagged Clone

CAT#: SC114421

PRKAG2 (untagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a


  "NM_016203" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PRKAG2
Synonyms AAKG; AAKG2; CMH6; H91620p; WPWS
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC114421 sequence for NM_016203 edited (data generated by NextGen Sequencing)
ATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCCCGGCGGGAGC
GGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACATTCCGGACCTG
AGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCT
CGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTTCTCCAGAGGC
CCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGACCAGCCCCGGC
TCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGC
ATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCAACTCCAACCCT
GCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCTCCGGCCTCTCC
TCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTAT
AAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACA
GGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCG
ACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCC
GGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGCAGTAGAAGACTCAGAAAGTGGTGTT
TACATGCGATTCATGAGGTCACACAAGTGTTATGACATCGTTCCAACCAGTTCAAAGCTT
GTTGTCTTTGATACTACATTACAAGTTAAAAAGGCCTTCTTTGCTTTGGTAGCCAACGGT
GTCCGAGCAGCGCCACTGTGGGAGAGTAAAAAACAAAGTTTTGTAGGAATGCTAACAATT
ACAGATTTCATAAATATACTACATAGATACTATAAATCACCTATGGTACAGATTTATGAA
TTAGAGGAACATAAAATTGAAACATGGAGGGAGCTTTATTTACAAGAAACATTTAAGCCT
TTAGTGAATATATCTCCAGATGCAAGCCTCTTCGATGCTGTATACTCCTTGATCAAAAAT
AAAATCCACAGATTGCCCGTTATTGACCCTATCAGTGGGAATGCACTTTATATACTTACC
CACAAAAGAATCCTCAAGTTCCTCCAGCTTTTTATGTCTGATATGCCAAAGCCTGCCTTC
ATGAAGCAGAACCTGGATGAGCTTGGAATAGGAACGTACCACAACATTGCCTTCATACAT
CCAGACACTCCCATCATCAAAGCCTTGAACATATTTGTGGAAAGACGAATATCAGCTCTG
CCTGTTGTGGATGAGTCAGGAAAAGTTGTAGATATTTATTCCAAATTTGATGTAATTAAT
CTTGCTGCTGAGAAAACATACAATAACCTAGATATCACGGTGACCCAGGCCCTTCAGCAC
CGTTCACAGTATTTTGAAGGTGTTGTGAAGTGCAATAAGCTGGAAATACTGGAGACCATC
GTGGACAGAATAGTAAGAGCTGAGGTCCATCGGCTGGTGGTGGTAAATGAAGCAGATAGT
ATTGTGGGTATTATTTCCCTGTCGGACATTCTGCAAGCCCTGATCCTCACACCAGCAGGT
GCCAAACAAAAGGAGACAGAAACGGAGTGA

Clone variation with respect to NM_016203.3
>OriGene 5' read for NM_016203 unedited
ATTTTGTTTACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGAGGAAGGACGCTTGA
ATTCGGCGCTTCGGCGGCGGCGGCGGCCGCGCGAGTTCCCTGCTCACCCTCCCTCTCCGC
GGAAGTCCCCACGAGGTGGCTTCAGGGTGTAACAGAGCGCGCGGCTCCAGTCCGAAGGCA
GCGGCCGGGGGAGGGAAGGAGGGGACCGAACCCCCGAGGAGTTTCGCAGAATCAACTTCT
GGTTAGAGTTATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCC
CGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACAT
TCCGGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAA
GCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTT
CTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGAC
CAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTC
CCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAGAGTCTTCCCCCAAC
TCCAACCCTGCTACCTCGCCCGGGGGCATTAAGTTTTTTCTCCCGCTCCAGAAAACCTTC
GGGCTCTTCTCCTCTCCGGCACCACCACCCAGTGACCAAGCAGCACACGTTTCCCCTGGA
ATCCCTAAGCACGAGCCTCGACCGGTAAGAGATCGCATTTATGCCTCGGTTTCCCCCCGG
ACACAGGGCAACAGTTTTGCCCT
>OriGene 3' read for NM_016203 unedited
CGGGGGACCTTTGGNNGATGGCAACTTNCCAGTTCCAGGNANAGCACTGGGGNAGGGTCA
CAGGATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTC
GAGTTTTTTTTTTTTTTTTTTCATGGATGTGGTGAAGTTTATTCCACCAAAAGATGTGTA
AAAAAATTGCATGAAAGTAAAAATAAATAAAGCTGTTGTAAAGCAGCCTCGTTGACACGG
TAGCCCAGAACAAAACACTTACGTGTAAAAGTGTCATTACAATTTTAAAGTAATTATTTA
TATTCAAATTACAACTTTTTGACAAATCTAAAGAAAACAAACTGATTTGGTAAAAGGTTC
AAAGACTTCCACATTCAAGCTCGGTGTTGTTTCACACGCGTGCGCCCCGGCTGCGGCGGT
GACATATTGCTGTATTCGGACATAAGGCACTGTGATCTGAACATACCGTGCACTCACCTT
ATGCCACATCACCTGTTCCATACCAGTGAATTCTTTGAAATGAAAAATAATGAAAACTTC
AGGACACAGTGCACTTTAATGACATACAGCATTTAAAATCCTTCAGACAAAGGTCTGAAA
ACAGTCTTTTAATGCAAGCCTGAATCTTCAAGCACATAAAATCTTTCTTTTTTAAGCTTA
ATTTCAACATCACTGGAAGAAATACCTATTGTTAAAACCCTGATATACATTCTTAACCAC
TTGCAACCCGTGGTCATGAGGCCAAACGTGGCCCAGAAACTTTTTTCAAATTCTCCTCCT
AGGGCGTCTACATTTCCGGGGGGGCACCTCCGTTTCTGTCTCCTTTTGTTTGGCACCTGG
TGGTGTGAGAATCAAGCCTTGCAAAATGTTCAAAAG
Restriction Sites NotI-NotI     
ACCN NM_016203
ORF Size 1710 bp
Insert Size 2600
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_016203.2, NP_057287.2
RefSeq Size 2062
RefSeq ORF 1710
Locus ID 51422
Domains CBS
Protein Families Druggable Genome
Protein Pathways Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway
Gene Summary AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (a, also referred to as PRKAG2-a).

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