PPME1 (NM_016147) Human Untagged Clone

CAT#: SC114434

PPME1 (untagged)-Human protein phosphatase methylesterase 1 (PPME1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPME1
• Synonyms: ABDH19; PME-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114434 sequence for NM_016147 edited (data generated by NextGen Sequencing)
  ATGTCGGCCCTCGAAAAGAGCATGCACCTCGGCCGCCTTCCCTCTCGCCCACCTCTACCC
  GGCAGCGGGGGCAGTCAGAGCGGAGCCAAGATGCGAATGGGCCCTGGAAGAAAGCGGGAC
  TTTTCCCCTGTTCCTTGGAGTCAGTATTTTGAGTCCATGGAAGATGTAGAAGTAGAGAAT
  GAAACTGGCAAGGATACTTTTCGAGTCTACAAGAGTGGTTCAGAGGGTCCAGTCCTGCTC
  CTTCTGCATGGAGGAGGTCATTCTGCCCTTTCTTGGGCTGTGTTCACGGCAGCGATTATT
  AGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTC
  AAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAA
  GCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCT
  ATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATT
  GATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGT
  CGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAG
  ATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGA
  ATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAA
  GATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGACCAAG
  AAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGC
  TGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTG
  GCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAG
  ATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCT
  GAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTCCAG
  TGTGTGTTTCCTGGCTGTTAG
  
  Clone variation with respect to NM_016147.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016147 unedited
  TTCAGGATTTGTAATACGACTCACTTATAGGGCGGCCGCGAATCGGCACGAGGCCAAAGG
  CGACAGGGCGTCGTTAGGGGAGCGAGTCGTGACCGGTTGGGCCACACTCAACGTGGGACG
  AAGCTTCGCCTACTGTTTGACTACGTGCGTGCAGCCTCCCCTCGATGTCGGCCCTCGAAA
  AGAGCATGCACCTCGGCCGCCTTCCCTCTCGCCCACCTCTACCCGGCAGCGGGGGCAGTC
  AGAGCGGAGCCAAGATGCGAATGGGCCCTGGAAGAAAGCGGGACTTTTCCCCTGTTCCTT
  GGAGTCAGTATTTTGAGTCCATGGAAGATGTAGAAGTAGAGAATGAAACTGGCAAGGATA
  CTTTTCGAGTCTACAAGAGTGGTTCAGAGGGTCCAGTCCTGCTCCTTCTGCATGGAGGAG
  GTCATTCTGCCCTTTCTTGGGCTGTGTTCACGGCAGCGATTATTAGTAGAGTTCAGTGTA
  GGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATC
  TGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACC
  TTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAG
  CATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTANAAAGTA
  CAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCCGTCCTAAAACCTCC
  AAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCCCATTCCAAATCTGGAG
  TCTGCCCGGTCTCAATGGTTGGCCAGCCCAACAGTGTGAAGGAATTACCAGTTCCGTAGG
  GCTCAAATCTATAGTGCACGGATCCTACAGGAAGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016147 unedited
  AAGAAGCTAGGGGGANTATTTAACCTTNCTTTTAAACAGGGTCATAAATAACAAAAACAA
  GTAGGTCCCAGACTCCGGACCATGCAGCAGGACAGGGGTGGGAGGTTGTTGAGTGGAAAG
  GTGGAGGGGGCTACACATCACCTAAGACAGTCACAGAAAAGATGGGCTTCAGGACACTGC
  CCCTTCCTGCCCTTGGAAATGGCGTGCCTGGGCAATAGGGACAGGCCACAGTGCTGTGTC
  GAGGCAGCTGGAAGAAGGCAAAGACTGGGGATGCCAGGCTGTAATGTTTCTGTGTGGAGT
  GATGTGAAATCCACAAATGGCAAAGAGAAGCTGTAGGTTTGAAGAAGCAAGGGGGCACTG
  CACACCTCCAGGAACCAGTTATGAAAATGGTTAAATTTGATGATTAAAAACAATTCCATA
  GGCTTTGGCCTGTGGCTTTGTGCATGGGCTGTATTTAACCTGGGTTGCTCTGTGGCAGGT
  GAGGGCGCAGGAGGCCCCTGGAGCAGCCTGGCCTCAGCCCAGGGCAGGTGCCCAGACATG
  TGGGAGTGGGACAGTGGGCTCTCCCAGATGGGAGGCCATGTGCTTGGACCGGCTGGACCT
  GATTTTCAAGCTCGTTTCTTGTGATGCTATCCACCACCACCGCTCGCTATGGCTAAGGAT
  GGGATCTTGGCCTCTCTGGGTCTTCCAAACCTGGAAGAGTACGACTGGGATAAAACCGTA
  CCTGACTAGTGTTTTATTTGAAAGGGAAAAATAAAGACCCACCCCATGCATTGTCCATCC
  CATGAAGGCAGGCTGGGCCATGCCAAGACAATCTCAAGAATGGAGGTCCCTGAGCCTGGG
  AAGACATTTGAACTCANATGTTCGCCCTGAGCTAGGAAAAAGGCTCAATATTGCCAAACC
  TGGAGGCTTTACCCTAGGCACCCAGGGAGAGCCGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016147
• ORF Size: 1161 bp
• Insert Size: 2620
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016147.1, NP_057231.1
• RefSeq Size: 2484
• RefSeq ORF: 1161
• Locus ID: 51400
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (a).