ARNT2 (NM_014862) Human Untagged Clone

CAT#: SC114814

ARNT2 (untagged)-Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARNT2
• Synonyms: bHLHe1; WEDAS
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114814 sequence for NM_014862 edited (data generated by NextGen Sequencing)
  ATGGCAACCCCGGCGGCGGTCAACCCTCCGGAAATGGCTTCAGACATACCTGGATCTGTG
  ACGTTGCCCGTTGCCCCCATGGCGGCCACCGGACAGGTGAGGATGGCGGGGGCCATGCCT
  GCCCGTGGAGGAAAGCGGCGTTCCGGAATGGACTTCGATGATGAAGATGGTGAAGGCCCC
  AGTAAATTTTCANNNGAGAATCATAGTGAAATCGAAAGGCGCAGACGGAACAAGATGACT
  CAGTACATCACGGAGCTCTCCGACATGGTCCCCACATGCAGCGCACTGGCTCGGAAGCCA
  GACAAGCTCACCATCCTCCGCATGGCCGTCTCGCACATGAAGTCCATGAGGGGTACAGGG
  AACAAGTCCACCGATGGCGCGTACAAGCCTTCCTTCCTCACAGAGCAGGAACTGAAGCAT
  CTCATCCTTGAAGCAGCTGATGGATTTCTGTTTGTGGTGGCTGCTGAGACAGGGCGAGTG
  ATTTATGTGTCTGACTCCGTCACCCCTGTTCTGAACCAGCCCCAGTCAGAGTGGTTTGGG
  AGCACACTGTATGAACAGGTGCATCCTGATGACGTGGAGAAGCTGAGAGAGCAACTGTGC
  ACCTCAGAAAACTCAATGACAGGCCGGATCTTGGACCTGAAGACTGGGACGGTCAAGAAA
  GAAGGGCAGCAGTCATCCATGAGGATGTGCATGGGCTCGCGGCGGTCTTTCATCTGCAGG
  ATGAGGTGTGGAAATGCTCCTTTGGACCACCTTCCTCTAAACAGAATAACCACCATGAGG
  AAAAGGTTCAGGAATGGCCTTGGCCCTGTGAAAGAAGGAGAAGCCCAATATGCTGTGGTC
  CACTGTACAGGATACATCAAGGCCTGGCCACCAGCAGGAATGACCATACCTGAAGAAGAC
  GCTGATGTGGGACAAGGCAGTAAATATTGCCTCGTGGCAATTGGGAGACTCCAGGTGACC
  AGCTCTCCTGTATGCATGGACATGAATGGGATGTCGGTGCCCACAGAGTTCTTATCCCGG
  CATAACTCCGATGGAATCATCACATTTGTGGATCCAAGATGTATCAGTGTGATTGGCTAC
  CAACCCCAGGATCTTCTGGGAAAGGACATTTTGGAATTCTGCCACCCTGAGGATCAAAGC
  CATCTGCGTGAGAGCTTCCAGCAGGTGGTTAAGCTGAAAGGCCAAGTCCTGTCGGTCATG
  TATCGATTTCGCACCAAGAACCGGGAGTGGATGTTGATCCGCACCAGCAGCTTCACATTC
  CAGAATCCCTATTCTGATGAGATTGAGTACATCATCTGCACCAACACCAACGTCAAGCAA
  CTTCAGCAACAGCAGGCAGAATTGGAAGTGCACCAGAGAGATGGATTGTCATCGTATGAC
  TTATCCCAGGTCCCCGTCCCCAACCTACCAGCCGGTGTTCATGAGGCCGGGAAGTCCGTG
  GAAAAGGCGGATGCAATCTTCTCCCAGGAAAGAGATCCTCGGTTTGCTGAAATGTTTGCA
  GGAATTAGTGCATCGGAGAAGAAGATGATGAGCTCAGCCTCTGCAGCAGGAACCCAGCAG
  ATCTACTCCCAAGGAAGCCCATTTCCCTCTGGACACTCCGGGAAGGCCTTCAGCTCTTCA
  GTGGTTCATGTGCCTGGAGTGAATGATATTCAGTCCTCTTCTTCCACGGGCCAGAACATG
  TCCCAAATCTCCCGGCAGCTAAACCAGAGTCAGGTGGCATGGACAGGGAGTCGTCCGCCC
  TTTCCGGGACAGCAAATCCCATCTCAGTCCAGCAAGACTCAGTCATCTCCCTTTGGGATT
  GGAACGAGCCACACCTACCCGGCAGACCCCTCTTCCTACAGCCCCCTCTCCAGCCCAGCT
  ACCTCCTCGCCAAGTGGGAATGCCTACTCCAGTCTTGCCAACAGGACTCCAGGGTTCGCT
  GAAAGTGGACAAAGTAGCGGGCAGTTCCAAGGGCGGCCCTCGGAAGTCTGGTCGCAGTGG
  CAAAGCCAGCACCATGGCCAGCAGAGCGGTGAGCAGCACTCCCACCAGCAGCCCGGTCAG
  ACTGAAGTGTTCCAGGACATGCTGCCCATGCCAGGAGATCCAACCCAGGGGACTGGCAAC
  TATAACATCGAAGACTTTGCCGACCTGGGCATGTTTCCACCGTTTTCTGAGTAG
  
  Clone variation with respect to NM_014862.3
  193 a=>n;194 g=>n;195 a=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014862 unedited
  GTAACGTTCCAATTTGTATACGACTCATATAGGCGGCCGCGAATTCGCACGAGGGGAGCG
  CCGCCCGCCCGCGCCGTCCTTTGTGTGGCGGCGGCGGCGCCTGGTCCTGACCGGGTCCCC
  GGGGCTGAGCGCCGGGCTCCGCGCCGCCCCTCCCGCGCCCCTGCCAAGCGGGCGCCTATC
  CTCTCCGAGCAAGATGGCAACCCCGGCGGCGGTCAACCCTCCGGAAATGGCTTCAGACAT
  ACCTGGATCTGTGACGTTGCCCGTTGCCCCCATGGCGGCCACCGGACAGGTGAGGATGGC
  GGGGGCCATGCCTGCCCGTGGAGGAAAGCGGCGTTCCGGAATGGACTTCGATGATGAAGA
  TGGTGAAGGCCCCAGTAAATTTTCAAGAGAATCATAGTGAAATCGAAAGGCGCAGACGGA
  ACAAGATGACTCAGTACATCACGGAGCTCTCCGACATGGTCCCCACATGCAGCGCACTGG
  CTCGGAAGCCAGACAAGCTCACCATCCTCCGCATGGCCGTCTCGCACATGAAGTCCATGA
  GGGGTACAGGGAACAAGTCCACCGATGGCGCGTACAAGCCTTCCTTCCTCACAGAGCAGG
  AACTGAAGCATCTCATCCTTGAAGCAGCTGATGGATTTCTGTTTGTGGTGGCTGCTGAGA
  CAGGGCGAGTGATTTATGTGTCTGACTCCGTCACCCCTGTTCTGAACCAGCCCCAGTCAG
  AGTGGTTTGGGAGCACACTGTATGAACAGGTGCATCCTGATGACGTGGAGAAGCTGAGAG
  AGCAACTGTGCACCTCAGATAACTCAATGACAGGCCGGATCTTGGACCTGAAGACTGGGA
  CGGTCAAGATAGAATGGCAGCAGTCATCCATGAAGATGTGCATGGGCTCGCGGCGGTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014862 unedited
  ATGTACGCGGCCGCATCTATAGTCGGTTTTTTTTTTTTTTTTTTAAAGGAAACTGAGATT
  GTTAGATGAAGCAAGCCGTCCTGCTCCCGCACAGCCTGTGAAACCTCCATTTTGCCACTT
  TCAAGGTCAGTGCCCCACAGACCCTGGCCTGTTGTTGACCATAACACTAGCTTTGGCCAC
  AAAAGCCAGGGACACCTACGCTTGGAAATGTGCCTGCACCACTGTGTGGTGCCTCCTTAA
  GTTGCCCCACACTCCACATGGCCAAAGAAAAGGTGAATGTCCAGGTGGTTTATTGGCTTC
  TTATTATGGGGTGTTTGGTGGGGAATGACCCCGGTAGGTTAGGAGACAGTGACTTAGGTC
  AAGTCCATATTTTCTGGTTTTATAAAGGACACTCGTATTCTGACTTGCGATTTCTATAGC
  TGTAAGGGTTACTGTCTGTTTACTGTTATATGTGGTTCGCTATAACCGTCACGGTATTAG
  GTGAGTGCTCCATTGTTATGTTCCTTATGGACTCTTTAAGTGCCGTCCTCAGTGGTCAGA
  CTATTTCTTTATTTGAATATGTTGTCTTTTTTGTTTTTGCCCTTAAGTCTTCATGTTATT
  CTGTATTCATCGCATCCCGTAATCACATCTAAATATCTTCTCCTCTTCTNCTCACTTCTC
  TCTCTCTCTTATCACCTCGATTTCGCCCCTCACCTCTTCCTTCCTTCTGCTATTTCTCCA
  TATGCTCTCTCCTTCATCTCTCTATGTGTTCTCCCCTCTTTGCCCTTCATTTCGCTTCCC
  CCTTCTTCTTCTTCCTCATCTTCTCTTTATTCTTCTTCTGCACCCCTCGCTCCNCACTAT
  CTTACTCTTTCCTCTTCCTAATTCTTTTTTCACACTCACCCTCCTCTACTTCTCTCTCTC
  TTGTCCTGATCTTGTCATCCTATTAGTGATTCCTCATCTTATCATTTCCTACCTTCGATT
  CTAATCTACCTACACCCCCTCCTCTTCGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014862
• ORF Size: 2154 bp
• Insert Size: 6930
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014862.3, NP_055677.3
• RefSeq Size: 6576
• RefSeq ORF: 2154
• Locus ID: 9915
• Domains: PAS, HLH, PAC
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Pathways in cancer, Renal cell carcinoma
• Gene Summary: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]