RASD2 (NM_014310) Human Untagged Clone

CAT#: SC115073

RASD2 (untagged)-Human RASD family, member 2 (RASD2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASD2
• Synonyms: Rhes; TEM2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115073 sequence for NM_014310 edited (data generated by NextGen Sequencing)
  ATGATGAAGACTTTGTCCAGCGGGAACTGCACGCTCAGTGTGCCCGCCAAAAACTCATAC
  CGCATGGTGGTGCTGGGTGCCTCTCGGGTGGGCAAGAGCTCCATCGTGTCTCGCTTCCTC
  AATGGCCGCTTTGAGGACCAGTACACACCCACCATCGAGGACTTCCACCGTAAGGTATAC
  AACATCCGCGGCGACATGTACCAGCTCGACATCCTGGATACCTCTGGCAACCACCCCTTC
  CCCGCCATGCGCAGGCTGTCCATCCTCACAGGGGATGTCTTCATCCTGGTGTTCAGCCTG
  GATAACCGGGAGTCCTTCGATGAGGTCAAGCGCCTTCAGAAGCAGATCCTGGAGGTCAAG
  TCCTGCCTGAAGAACAAGACCAAGGAGGCGGCGGAGCTGCCCATGGTCATCTGTGGCAAC
  AAGAACGACCACGGCGAGCTGTGCCGCCAGGTGCCCACCACCGAGGCCGAGCTGCTGGTG
  TCGGGCGACGAGAACTGCGCCTACTTCGAGGTGTCGGCCAAGAAGAACACCAACGTGGAC
  GAGATGTTCTACGTGCTCTTCAGCATGGCCAAGCTGCCACACGAGATGAGCCCCGCCCTG
  CATCGCAAGATCTCCGTGCAGTACGGTGACGCCTTCCACCCCAGGCCCTTCTGCATGCGC
  CGCGTCAAGGAGATGGACGCCTATGGCATGGTCTCGCCCTTCGCCCGCCGCCCCAGCGTC
  AACAGTGACCTCAAGTACATCAAGGCCAAGGTCCTTCGGGAAGGCCAGGCCCGTGAGAGG
  GACAAGTGCACCATCCAGTGA
  
  Clone variation with respect to NM_014310.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014310 unedited
  GTTTTGCGGAANNNGNNAAACGACTCACTATAGGGCGGCNCGCGATTCGGCACCAGGCGG
  CTGGAGCAGCAGGCAGCTCCCCGCAGCTCCCGGCGCTTCCAGGCAGCTCTCTGAGCCGTG
  CCAGAGGCCCGGCCCGCCATTCCCAGCCCCGAGCCATGATGAAGACTTTGTCCAGCGGGA
  ACTGCACGCTCAGTGTGCCCGCCAAAAACTCATACCGCATGGTGGTGCTGGGTGCCTCTC
  GGGTGGGCAAGAGCTCCATCGTGTCTCGCTTCCTCAATGGCCGCTTTGAGGACCAGTACA
  CACCCACCATCGAGGACTTCCACCGTAAGGTATACAACATCCGCGGCGACATGTACCAGC
  TCGACATCCTGGATACCTCTGGCAACCACCCCTTCCCCGCCATGCGCAGGCTGTCCATCC
  TCACAGGGGATGTCTTCATCCTGGTGTTCAGCCTGGATAACCGGGAGTCCTTCGATGAGG
  TCAAGCGCCTTCAGAAGCAGATCCTGGAGGTCAAGTCCTGCCTGAAGAACAAGACCAAGG
  AGGCGGCGGAGCTGCCCATGGTCATCTGTGGCAACAAGAACGACCACGGCGAGCTGTGCC
  GCCAGGTGCCCACCACCGAGGCCGAGCTGCTGGTGTCGGGCGACGAGAACTGCGCCTACT
  TCGAGGTGTCGGCCAAGAAAGACACCAACGTGGACGAGATGTTCTACGTGCTCTTCAGCA
  TGGCCAAGCTGCCACACGAGATGAGCCCCGCCCTGCNATCGCAGATCTCCGTGCAGTACG
  GTGACGCCTTTCACCCCCAGCCTTCTGCATGCGCCGCGTCAGGAGATGGACGCCTATGGC
  ATGGTCTCGCCCTTCGCCGCCGCCCNAGCGTNACAGTGACCTCAGTACATCAGGCCCANG
  TTCTTTTCGGAAGCCAGCCCGTGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014310 unedited
  GAACCGCGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTTGTAACAAACCCACTTT
  TATTGATAGTGTACACGCGAAATCCATGTGTGGCGGGGNCTGTGCCTGGGTGAGAGCGGG
  CCACACACCGGTGCAGCCAAGGTACCTGGTCTGCTCAGAAGGCTCAGGCAGTGGGTGGGG
  AAGGGGACAGAGGCAGGGTTGGAGCTGCTGCTTTGAGCACAGACGCAGGCAGGGGCCAAG
  GCTGGGGTGCAGGTGCAGGTATGCAGAGCTGGGGCTGGAGCATGTGTACATCTGTGTGTA
  CATCTGTGTGTACTTGTCTATACATGGGCATGGTGTACACAATATTTCCAGGACCCTTTC
  ATTCTGCTCTTAGGACATGTCTCAGGACAATATTTTCTTCCTTCCTTTATCCCCTTCGCT
  CCAACTTTCTTATATTTACCCATCTTTTCTTTCCCCTCCTCTCCTCTTTACCTCCCTTTC
  TCCTTCACACCTTCCCCCTCTTTTCTCCTCCACTTCCTACTCTCTCTTTCCTCTCTTCCC
  CCCCTTACCAACTTTCTCCCCTCACTCTTATCTTTTTTTCCTCCTTTCTTCATCGTCTTC
  ATCTCCTTCTACTTTTTCCTCCTCTCCCCTCCTGTTCCTCTTTTCCCTTCTCCATTCCCG
  TTCATCTTCCTTTCTTTTTTCATTCCTTTGTCCTGTTTTTCTTCCCCCCCTTTTTCTTTT
  TTTTTTCCTTATTCCTCTCTTTCCCCCCTTCTCCTTTCCCCTTTTGTTTTTCTCTTACTC
  TCCCTTTCCCCTTCCGCTCTCCTCTTTTCTCCTAATCCCTGCACGCCCCTCTTTTTCCCC
  CCCTCTCGATTTTACCCTTCTCATTATTTTCCTCGTCTCTCGCCGTGTGTTTCTCCGCCT
  CCCCTCCCGCCGTTTATACTTCCTTCATTATTATTCTTGGTATTCTTTATTTCTGACTGT
  TCTTTCCTTCGTCCCCTTTTCTCTGTTCCTTATCTTACTATTTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014310
• ORF Size: 801 bp
• Insert Size: 2940
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014310.3, NP_055125.2
• RefSeq Size: 3047
• RefSeq ORF: 801
• Locus ID: 23551
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Gene Summary: This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]