RASD2 (NM_014310) Human Untagged Clone

CAT#: SC324438

RASD2 (untagged)-Human RASD family, member 2 (RASD2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASD2
• Synonyms: Rhes; TEM2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014310.3 GTCCCTTGCGCCTCCTTGCCCGGCCGCGCCCAGCCCGGCGTCCCGAGCAGCGCAGGGGAG
  GATCCCCGCGCAGTGACCCGGGAGCCACCACAGACTCTGGGAGGCTCGGCGGCTGGAGCA
  GCAGGCAGCTCCCCGCAGCTCCCGGCGCTTCCAGGCAGCTCTCTGAGCCGTGCCAGAGGC
  CCGGCCCGCCATTCCCAGCCCCGAGCCATGATGAAGACTTTGTCCAGCGGGAACTGCACG
  CTCAGTGTGCCCGCCAAAAACTCATACCGCATGGTGGTGCTGGGTGCCTCTCGGGTGGGC
  AAGAGCTCCATCGTGTCTCGCTTCCTCAATGGCCGCTTTGAGGACCAGTACACACCCACC
  ATCGAGGACTTCCACCGTAAGGTATACAACATCCGCGGCGACATGTACCAGCTCGACATC
  CTGGATACCTCTGGCAACCACCCCTTCCCCGCCATGCGCAGGCTGTCCATCCTCACAGGG
  GATGTCTTCATCCTGGTGTTCAGCCTGGATAACCGGGAGTCCTTCGATGAGGTCAAGCGC
  CTTCAGAAGCAGATCCTGGAGGTCAAGTCCTGCCTGAAGAACAAGACCAAGGAGGCGGCG
  GAGCTGCCCATGGTCATCTGTGGCAACAAGAACGACCACGGCGAGCTGTGCCGCCAGGTG
  CCCACCACCGAGGCCGAGCTGCTGGTGTCGGGCGACGAGAACTGCGCCTACTTCGAGGTG
  TCGGCCAAGAAGAACACCAACGTGGACGAGATGTTCTACGTGCTCTTCAGCATGGCCAAG
  CTGCCACACGAGATGAGCCCCGCCCTGCATCGCAAGATCTCCGTGCAGTACGGTGACGCC
  TTCCACCCCAGGCCCTTCTGCATGCGCCGCGTCAAGGAGATGGACGCCTATGGCATGGTC
  TCGCCCTTCGCCCGCCGCCCCAGCGTCAACAGTGACCTCAAGTACATCAAGGCCAAGGTC
  CTTCGGGAAGGCCAGGCCCGTGAGAGGGACAAGTGCACCATCCAGTGAGCGAGGGATGCT
  GGGGCGGGGCTTGGCCAGTGCCTTCAGGGAGGTGGCCCCAGATGCCCACTGTGCGCATCT
  CCCCACCGAGGCCCCGGCAGCAGTCTTGTTCACAGACCTTAGGCACCAGACTGGAGGCCC
  CCGGGCGCTGGCCTCCGCACATTCGTCTGCCTTCTCACAGCTTTCCTGAGTCCGCTTGTC
  CACAGCTCCTTGGTGGTTTCATCTCCTCTGTGGGAGGACACATCTCTGCAGCCTCAAGAG
  TTAGGCAGAGACTCAAGTTACACCTTCCTCTCCTGGGGTTGGAAGAAATGTTGATGCCAG
  AGGGGTGAGGATTGCTGCGTCATATGGAGCCTCCTGGGACAAGCCTCAGGATGAAAAGGA
  CACAGAAGGCCAGATGAGAAAGGTCTCCTCTCTCCTGGCATAACACCCAGCTTGGTTTGG
  GTGGCAGCTGGGAGAACTTCTCTCCCAGCCCTGCAACTCTTACGCTCTGGTTCAGCTGCC
  TCTGCACCCCCTCCCACCCCCAGCACACACACAAGTTGGCCCCCAGCTGCGCCTGACATT
  GAGCCAGTGGACTCTGTGTCTGAAGGGGGCGTGGCCACACCTCCTAGACCACGCCCACCA
  CTTAGACCACGCCCACCTCCTGACCGCGTTCCTCAGCCTCCTCTCCTAGGTCCCTCCGCC
  CGACAGTTGTGCTTTGTTGTGGTTGCAGCTGTTTTCGTGTCATGTATAGTAGTAGAAATG
  GAAATCATTGTACTGTAAAAGCCTAGTGACTCCCTCCTTGGCCAGGCCCTCACCCAGTTC
  AGATCCACGGCCTCCACCCGGGACGCCTTCCTCCTCTGCTCCCAAACAGGGTTTCCGTGG
  CCTGTTTGCAGCTAGACATTGACCTCCGCCATTGAGCTCCACGGTTTACAGACAATTGCA
  CAAGCGTGGGGTGGGCAGGCCAGGACTGCTTTTTTTTAATGCTCCCATTTCACAGAGGAT
  ACCACCGAGACTCGGAGGGGACACGATGAGCACCAGGCCCCACCTTTGTCCCCTAGCAAA
  TTCAGGGTACAGCTCCACCTAGAACCAGGCTGCCCTCTACTGTGCTCGTTCCTCAAGCAT
  TTATTAAGCACCTACTGGGTGCTGGGTTCACTGTGTCCTAGGAAACCAAGAGGGTCCCCA
  GTCCTGGCCTCTGCCCGCCCCTGCTGCCCCACCACCTTCTGCACACACAGCGGTGGGGAG
  GCGGGGAGGAGCAGCTGGGACCCAGAACTGAGCCTGGGAGGGATCCGACAGAAAAGCTCA
  GGGCGGGTCTTCTCCTTGTGCCCGGGATTGGGCTATGCTGGGTACCACCATGTACTCAGG
  CATGGTGGGTTTTGAACCCATAAACCAAAGGCCCTTGTCATCAGCTCTTAACAAGTATAT
  TTTGTATTTTAATCTCTCTAAACATATTGAAGTTTTAGGGCCCTAAGGAACCTTAGTGAT
  CTTCTATTGGGTCTTTCTGAGGTTCAGAGAGGGTAAGTAACTTCCTCCAGGTCACACAGC
  AAGTCTGTGGGTGGCAGAAGCAAGCTAGCACTGGGCATTCAGTACATACCACGATGTGCT
  CCCTCTCTTGATGCTTGGCCCCTGGGGCCTTCAGGGCTTTGGGACATCTTGTCCTCAACC
  CTCTCCCTAGATCAGTCTGTGAGGGTCCCTGTAGATATTGTGTACACCATGCCCATGTAT
  ATACAAGTACACACAGATGTACACACAGATGTACACATGCTCCAGCCCCAGCTCTGCATA
  CCTGCACCTGCACCCCAGCCTTGGCCCCTGCCTGCGTCTGTGCTCAAAGCAGCAGCTCCA
  ACCCTGCCTCTGTCCCCTTCCCCACCCACTGCCTGAGCCTTCTGAGCAGACCAGGTACCT
  TGGCTGCACCGGTGTGTGGCCCGCTCTCACCCAGGCACAGCCCCGCCACCATGGATCTCC
  GTGTACACTATCAATAAAAGTGGGTTTGTTACAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014310.3 unedited
  GGGCGATTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGTCCCTTGCG
  CCTCCTTGCCCGGCCGCGCCCAGCCCGGCGTCCCGAGCAGCGCAGGGGAGGATCCCCGCG
  CAGTGACCCGGGAGCCACCACAGACTCTGGGAGGCTCGGCGGCTGGAGCAGCAGGCAGCT
  CCCCGCAGCTCCCGGCGCTTCCAGGCAGCTCTCTGAGCCGTGCCAGAGGCCCGGCCCGCC
  ATTCCCAGCCCCGAGCCATGATGAAGACTTTGTCCAGCGGGAACTGCACGCTCAGTGTGC
  CCGCCAAAAACTCATACCGCATGGTGGTGCTGGGTGCCTCTCGGGTGGGCAAGAGCTCCA
  TCGTGTCTCGCTTCCTCAATGGCCGCTTTGAGGACCAGTACACACCCACCATCGAGGACT
  TCCACCGTAAGGTATACAACATCCGCGGCGACATGTACCAGCTCGACATCCTGGATACCT
  CTGGCAACCACCCCTTCCCCGCCATGCGCAGGCTGTCCATCCTCACAGGGGATGTCTTCA
  TCTTGGGTGTTCAGCCCTGGATAACCGGGAGTCCTTCGACGAGGTCAAGCCGCCCTCAGA
  AGCCGATCCTGGACGTCAAGTCCCTGGCCTGAAGCACAAGACCAAAGAGGGCGGCCGGAG
  CTCGCTCTATGTCTCATTTTGTGGCTCAAGAATTGATCACCGTCAGCCTGTGACCTACTG
  GTGCCCCACCAACTGAGGCCCACACTGCTGTTGTTCGGT
• Restriction Sites: Please inquire
• ACCN: NM_014310
• ORF Size: 801 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014310.3, NP_055125.2
• RefSeq Size: 3047
• RefSeq ORF: 801
• Locus ID: 23551
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Gene Summary: This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]