SETD2 (NM_014159) Human Untagged Clone

CAT#: SC115150

SETD2 (untagged)-Human SET domain containing 2 (SETD2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SETD2
• Synonyms: HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; p231HBP; SET2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014159, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCAGCTGCAGCCGCAGCCGCCTCCGAAGATGGGGGATTTCTACGACCCGGAGCACCCGACCCCTG
  AAGAAGAAGAAAATGAGGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAATGTTCAA
  AGGTGTTGCTTCTAGTCGATTTTTGCCCAAAGGCACCAAAACAAAAGTTAATTTGGAAGAACAGGGACGA
  CAGAAGGTGTCATTCAGCTTCAGCCTTACAAAGAAAACTTTGCAGAATAGGTTTCTCACTGCACTTGGCA
  ATGAAAAGCAAAGTGATACTCCAAACCCTCCAGCTGTACCTCTTCAGGTAGACTCGACTCCTAAAATGAA
  AATGGAAATTGGTGATACCTTATCTACTGCAGAAGAATCTTCCCCACCAAAGTCAAGGGTGGAATTGGGC
  AAAATTCATTTTAAGAAACATCTGCTTCATGTAACATCCAGGCCACTGCTGGCTACTACCACAGCAGTAG
  CATCTCCACCTACTCATGCAGCACCATTACCAGCAGTGATAGCAGAATCAACAACTGTAGACTCACCGCC
  CTCATCTCCGCCTCCACCGCCTCCACCTGCCCAAGCCACAACACTCTCATCACCAGCACCAGTAACAGAG
  CCAGTGGCCTTGCCACATACACCAATAACAGTTCTAATGGCAGCACCAGTACCCTTACCAGTAGATGTAG
  CAGTTAGATCTCTGAAAGAACCACCAATTATAATTGTACCAGAATCTTTAGAAGCAGATACTAAGCAGGA
  CACTATATCTAATAGTTTAGAAGAACACGTAACTCAAATATTGAATGAGCAAGCAGATATTTCCTCAAAA
  AAAGAAGATTCCCATATTGGGAAGGATGAAGAAATTCCAGATAGTTCTAAGATTAGTCTGAGCTGTAAAA
  AAACAGGTTCTAAGAAGAAATCCTCACAATCTGAAGGCATCTTTCTTGGTTCAGAATCTGATGAAGATTC
  TGTACGGACTTCTTCAAGTCAAAGATCACATGATTTAAAATTTTCAGCAAGCATTGAAAAGGAAAGAGAT
  TTTAAAAAGAGCTCAGCACCTTTAAAAAGTGAGGATCTAGGGAAACCTTCACGATCTAAAACAGACAGAG
  ATGATAAATATTTTAGCTATTCAAAACTTGAAAGAGATACTCGGTATGTATCTTCCCGATGTAGATCAGA
  AAGAGAGCGACGGCGGAGCAGATCTCACTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCC
  AGGTCAGAACGATCTCATTATTATGACTCTGATCGTCGCTACCATAGGAGCTCCCCTTATCGAGAGAGGA
  CGCGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAGTATAAGAA
  GACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGGACATCATCCTATTCTAAA
  TCTGATCGGGACTGTAAAACTGAGACCTCTTACTTAGAGATGGAAAGAAGAGGCAAGTATTCTTCAAAAC
  TAGAAAGAGAATCTAAAAGGACTTCAGAAAATGAAGCAATTAAAAGATGTTGTTCTCCCCCTAATGAACT
  GGGATTCCGACGAGGGTCATCATATTCTAAGCATGACAGTAGTGCTTCCCGTTATAAATCTACCCTTTCA
  AAACCTATACCCAAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAAC
  AGTCTCATTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAATAAAAATCC
  TGAAAGAGAAAAGGCTGGGTCTCCAGCTCCATCAAATCGATTAAATGATTCACCTACTTTAAAAAAGCTA
  GATGAATTGCCTATTTTTAAGTCCGAATTTATAACACATGATAGCCATGATAGTATTAAGGAATTAGACT
  CTTTATCTAAAGTGAAGAATGATCAATTAAGAAGTTTTTGTCCCATAGAATTAAATATAAATGGATCTCC
  TGGGGCAGAATCTGATTTGGCAACATTTTGCACTTCTAAAACTGATGCTGTTTTAATGACTTCTGATGAT
  AGTGTGACTGGATCGGAATTATCCCCTTTGGTCAAAGCATGCATGCTTTCATCAAATGGATTTCAGAATA
  TTAGTAGGTGCAAAGAAAAAGACTTGGATGATACCTGCATGCTGCATAAGAAGTCAGAAAGCCCATTTAG
  AGAAACAGAACCTCTGGTGTCACCACACCAAGATAAACTCATGTCTATGCCAGTTATGACTGTGGATTAT
  TCCAAAACAGTAGTTAAAGAACCAGTTGATACGAGGGTTTCTTGCTGCAAAACCAAAGATTCAGACATAT
  ACTGTACTTTGAACGATAGCAACCCTTCTTTGTGTAACTCTGAAGCTGAAAATATTGAGCCTTCAGTTAT
  GAAGATTTCTTCAAATAGCTTTATGAATGTGCATTTGGAATCAAAACCAGTTATATGTGATAGTAGAAAT
  TTGACAGATCACTCAAAATTTGCATGTGAAGAATATAAGCAGAGCATCGGTAGCACTAGTTCAGCTTCTG
  TTAATCATTTTGATGATTTATATCAACCTATTGGGAGTTCAGGTATTGCTTCATCTCTTCAGAGTCTTCC
  ACCAGGAATAAAGGTGGACAGTCTAACTCTCTTGAAATGCGGAGAGAACACATCTCCAGTTCTGGATGCA
  GTGCTAAAGAGTAAAAAAAGTTCAGAGTTTTTAAAGCATGCAGGGAAAGAAACAATAGTAGAAGTAGGTA
  GTGACCTTCCTGATTCAGGAAAGGGATTTGCTTCCAGGGAGAACAGGCGTAATAATGGGTTATCTGGGAA
  ATGTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCCTGAAAGAAGAGGAAGACCAGAAATCTCT
  TTAGATGAAAGAGGAGAAGGAGGACATGTGCATACTTCTGATGACTCAGAAGTTGTATTTTCTTCTTGTG
  ATTTGAATTTAACCATGGAAGACAGTGATGGTGTAACTTATGCATTAAAGTGTGACAGTAGTGGTCATGC
  CCCAGAAATTGTGTCTACAGTTCATGAAGATTATTCTGGCTCTTCTGAAAGTTCAAATGATGAAAGTGAT
  TCAGAAGATACAGATTCGGATGATAGCAGTATTCCAAGAAACCGTCTCCAGTCTGTTGTGGTTGTGCCAA
  AGAATTCTACTTTGCCCATGGAAGAAACAAGTCCTTGTTCTTCTCGGAGCAGTCAAAGTTATAGACACTA
  TTCTGACCATTGGGAAGATGAGAGATTGGAGTCAAGGAGACATTTGTATGAGGAAAAATTTGAAAGTATA
  GCAAGTAAAGCCTGTCCTCAAACTGATAAGTTTTTCCTTCATAAAGGAACAGAGAAGAATCCGGAAATTT
  CTTTTACACAGTCCAGTAGAAAACAAATAGATAATCGCCTGCCTGAACTTTCTCATCCTCAGAGTGATGG
  GGTTGATAGTACAAGTCATACAGATGTGAAATCTGACCCTCTGGGTCACCCAAATTCAGAGGAAACCGTG
  AAAGCCAAAATACCTTCTAGGCAGCAAGAAGAGCTGCCAATTTATTCTTCTGATTTTGAAGATGTCCCAA
  ATAAGTCTTGGCAACAGACCACTTTCCAAAACAGGCCAGATAGTAGACTGGGAAAAACAGAATTGAGTTT
  TTCTTCCTCTTGTGAGATACCACATGTGGATGGCTTGCACTCATCAGAAGAGCTCAGAAACTTAGGTTGG
  GACTTCTCTCAAGAAAAGCCTTCTACCACGTATCAGCAACCTGACAGTAGCTATGGAGCTTGTGGTGGAC
  ACAAGTATCAGCAAAATGCAGAACAGTATGGTGGGACACGTGATTACTGGCAAGGCAATGGTTACTGGGA
  TCCAAGATCAGGTAGACCTCCTGGAACTGGGGTTGTGTATGATCGAACTCAAGGACAAGTACCAGATTCC
  CTAACAGATGATCGTGAAGAAGAGGAGAATTGGGATCAACAGGATGGATCCCATTTTTCAGACCAGTCCG
  ATAAATTTCTTCTATCCCTTCAGAAAGACAAGGGGTCAGTGCAAGCACCTGAAATAAGCAGCAATTCCAT
  TAAGGACACTTTAGCTGTGAATGAAAAGAAAGATTTTTCAAAAAACTTAGAAAAAAATGATATCAAAGAT
  AGAGGGCCTCTTAAAAAAAGGAGGCAGGAAATAGAGAGTGATTCTGAAAGTGATGGTGAGCTTCAGGACA
  GAAAGAAAGTTAGAGTGGAGGTAGAGCAGGGAGAGACATCAGTGCCCCCAGGTTCAGCACTGGTTGGGCC
  CTCCTGTGTCATGGATGACTTCAGGGACCCACAGCGATGGAAGGAATGTGCCAAGCAAGGGAAAATGCCA
  TGTTACTTTGATCTTATTGAAGAAAATGTTTATTTAACAGAAAGAAAGAAGAATAAATCTCATCGAGATA
  TTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAAGATGAAAGAGCTCAAGGTGAAATAGCATGTGG
  GGAAGATTGTCTTAATCGTCTTCTCATGATTGAATGTTCTTCTCGGTGTCCAAATGGGGATTATTGTTCC
  AATAGACGGTTTCAGAGAAAACAGCATGCAGATGTGGAAGTCATACTCACAGAAAAGAAAGGCTGGGGCT
  TGAGAGCTGCCAAAGACCTTCCTTCGAACACCTTTGTCCTAGAATATTGTGGAGAGGTACTCGATCATAA
  AGAGTTTAAAGCTCGAGTGAAGGAGTATGCACGAAACAAAAACATCCATTACTATTTCATGGCCCTGAAG
  AATGATGAGATAATAGATGCCACTCAAAAAGGAAATTGCTCTCGTTTCATGAATCACAGCTGTGAACCAA
  ATTGTGAAACCCAAAAATGGACTGTGAACGGACAACTGAGGGTTGGGTTTTTTACCACCAAACTGGTTCC
  TTCAGGCTCAGAGTTAACGTTTGACTATCAGTTCCAGAGATATGGAAAAGAAGCCCAGAAATGTTTCTGC
  GGATCAGCCAATTGCCGGGGTTACCTGGGAGGAGAAAACAGAGTCAGCATCAGAGCAGCAGGAGGGAAAA
  TGAAGAAGGAACGATCTCGTAAGAAGGATTCAGTGGATGGAGAGCTAGAAGCTCTGATGGAAAATGGTGA
  GGGTCTCTCTGATAAAAACCAGGTGCTCAGCTTATCCCGGCTAATGGTTAGAATTGAAACTTTGGAGCAG
  AAACTTACCTGTCTGGAACTCATACAGAACACACACTCACAGTCCTGCCTGAAGTCCTTTCTGGAACGTC
  ATGGGCTGTCTTTGTTGTGGATCTGGATGGCAGAGCTAGGTGACGGCCGGGAAAGTAACCAGAAGCTTCA
  GGAAGAGATTATAAAGACTTTGGAACACTTGCCCATTCCTACTAAAAATATGTTGGAGGAAAGCAAAGTA
  CTTCCAATTATTCAACGCTGGTCTCAGACTAAGACTGCTGTCCCTCCGTTGAGTGAAGGAGATGGGTATT
  CTAGTGAGAATACATCGCGTGCTCATACACCACTCAACACACCTGATCCTTCCACCAAGCTGAGCACAGA
  AGCTGACACAGACACTCCCAAGAAACTAATGTTTCGCAGACTGAAAATTATAAGTGAAAATAGCATGGAC
  AGTGCAATCTCTGATGCAACCAGTGAGCTAGAAGGCAAGGATGGCAAAGAGGATCTTGATCAATTAGAAA
  ATGTCCCTGTAGAGGAAGAGGAAGAATTGCAGTCACAACAGCTACTCCCACAACAGCTGCCTGAATGCAA
  AGTTGATAGTGAAACCAACATAGAAGCTAGTAAGCTACCTACATCTGAACCAGAAGCTGACGCTGAAATA
  GAGCCCAAAGAGAGCAACGGCACAAAACTAGAAGAACCTATTAATGAAGAAACACCATCCCAAGATGAAG
  AGGAGGGTGTGTCTGATGTGGAGAGTGAAAGGAGCCAAGAACAGCCAGATAAAACAGTGGATATAAGTGA
  TTTGGCCACCAAACTCCTGGACAGTTGGAAAGACCTAAAGGAGGTATATCGAATTCCAAAGAAAAGTCAA
  ACTGAAAAGGAAAACACAACAACTGAACGAGGAAGGGATGCTGTTGGCTTCAGAGATCAAACACCTGCCC
  CGAAGACTCCTAATAGGTCAAGAGAGAGAGACCCAGACAAGCAAACTCAAAATAAAGAGAAAAGGAAACG
  AAGAAGCTCCCTCTCACCACCCTCTTCTGCCTATGAGCGGGGAACAAAAAGGCCAGATGACAGATATGAT
  ACACCAACTTCTAAAAAGAAAGTACGAATTAAAGACCGCAATAAACTTTCTACAGAGGAACGCCGGAAGT
  TGTTTGAGCAAGAGGTGGCTCAACGGGAGGCTCAGAAACAACAGCAACAGATGCAGAACCTGGGAATGAC
  ATCACCACTGCCCTATGACTCTCTTGGTTATAATGCCCCGCATCATCCCTTTGCTGGTTACCCACCAGGT
  TATCCCATGCAGGCCTATGTGGATCCCAGCAACCCTAATGCTGGAAAGGTGCTCCTGCCCACACCCAGCA
  TGGACCCAGTGTGTTCTCCTGCTCCTTATGATCATGCTCAGCCCTTGGTGGGACATTCTACAGAACCCCT
  TTCTGCCCCTCCACCAGTACCAGTGGTGCCACATGTGGCAGCTCCTGTGGAAGTTTCCAGTTCCCAGTAT
  GTGGCCCAGAGTGATGGTGTAGTACACCAAGACTCCAGCGTTGCTGTCTTGCCAGTGCCGGCCCCCGGCC
  CAGTTCAGGGACAGAATTATAGTGTTTGGGATTCAAACCAACAGTCTGTCAGTGTACAGCAGCAGTACTC
  TCCTGCACAGTCTCAAGCAACCATATATTATCAAGGACAGACATGTCCAACAGTCTATGGTGTGACATCA
  CCTTATTCACAGACAACTCCACCAATTGTACAGAGTTATGCCCAGCCAAGTCTTCAGTATATCCAGGGGC
  AACAGATTTTCACAGCTCATCCACAAGGAGTGGTGGTACAGCCAGCCGCAGCAGTGACTACAATAGTTGC
  ACCAGGGCAGCCTCAGCCCTTGCAGCCATCTGAAATGGTTGTGACAAATAATCTCTTGGATCTGCCGCCC
  CCCTCTCCTCCCAAACCAAAAACCATTGTCTTACCTCCCAACTGGAAGACAGCTCGAGATCCAGAAGGGA
  AGATTTATTACTACCATGTGATCACAAGGCAGACTCAGTGGGATCCTCCTACTTGGGAAAGCCCAGGAGA
  TGATGCCAGCCTTGAGCATGAAGCTGAGATGGACCTGGGAACTCCAACATATGATGAAAACCCCATGAAG
  GCCTCGAAAAAGCCCAAGACAGCAGAAGCAGACACCTCCAGTGAACTAGCAAAGAAAAGCAAAGAAGTAT
  TCAGAAAAGAGATGTCCCAGTTCATCGTCCAGTGCCTGAACCCTTACCGGAAACCTGACTGCAAAGTGGG
  AAGAATTACCACAACTGAAGACTTTAAACATCTGGCTCGCAAGCTGACTCACGGTGTTATGAATAAGGAG
  CTGAAGTACTGTAAGAATCCTGAGGACCTGGAGTGCAATGAGAATGTGAAACACAAAACCAAGGAGTACA
  TTAAGAAGTACATGCAGAAGTTTGGGGCTGTTTACAAACCCAAAGAGGACACTGAATTAGAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014159 unedited
  NGTGCAAATTTTGTAATACGACTCACTATAGGGCGGCNCGCGATTCGGCACGAGGGCAGA
  TCTCACTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCCAGGTCAGAACGA
  TCTCATTATTATGACTCTGATCGTCGCTACCATAGGAGCTCCCCTTATCGAGAGAGGACG
  CGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAG
  TATAAGAAGACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGG
  ACATCATCCTATTCTAAATCTGATCGGGACTGTAAAACTGAGACCTCTTACTTAGAGATG
  GAAAGAAGAGGCAAGTATTCTTCAAAACTAGAAAGAGAATCTAAAAGGACTTCAGAAAAT
  GAAGCAATTAAAAGATGTTGTTCTCCCCCTAATGAACTGGGATTCCGACGAGGGTCATCA
  TATTCTAAGCATGACAGTAGTGCTTCCCGTTATAAATCTACCCTTTCAAAACCTATACCC
  AAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAACAG
  TCTCATTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAAT
  AAAAATCCTGAAAGAGAAAAGGCTGGGTCTCCAGCTCCATCAAATCGATTAAATGATTCA
  CCTACTTTAAAAAAGCTAGATGAATTGCCTATTTTTAAGTCCGAATTATAACACATGATA
  GCCATGATAGTATTAAGGAATTAGACTCTNTATCTAAAGTGAAGAATGATCAATTAAGAA
  GNTTTTGTCCCATAGAATAAATATAATGGGNATCTCTGGGCAGAATCTGATTTGGCAAAC
  ATTTGCACTTCTAAACTGATGCTGNNTTATGACTCTGATGAAGTGTGACTGGATCGAATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014159
• ORF Size: 6186 bp
• Insert Size: 6300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014159.3, NP_054878.3
• RefSeq Size: 8452
• RefSeq ORF: 6186
• Locus ID: 29072
• Domains: WW, SET, PostSET, AWS
• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation
• Gene Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).