DKK3 (NM_013253) Human Untagged Clone

CAT#: SC115308

DKK3 (untagged)-Human dickkopf homolog 3 (Xenopus laevis) (DKK3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DKK3
• Synonyms: REIC; RIG
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115308 sequence for NM_013253 edited (data generated by NextGen Sequencing)
  ATGCAGCGGCTTGGGGCCACCCTGCTGTGCCTGCTGCTGGCGGCGGCGGTCCCCACGGCC
  CCCGCGCCCGCTCCGACGGCGACCTCGGCTCCAGTCAAGCCCGGCCCGGCTCTCAGCTAC
  CCGCAGGAGGAGGCCACCCTCAATGAGATGTTCCGCGAGGTTGAGGAACTGATGGAGGAC
  ACGCAGCACAAATTGCGCAGCGCGGTGGAAGAGATGGAGGCAGAAGAAGCTGCTGCTAAA
  GCATCATCAGAAGTGAACCTGGCAAACTTACCTCCCAGCTATCACAATGAGACCAACACA
  GACACGAAGGTTGGAAATAATACCATCCATGTGCACCGAGAAATTCACAAGATAACCAAC
  AACCAGACTGGACAAATGGTCTTTTCAGAGACAGTTATCACATCTGTGGGAGACGAAGAA
  GGCAGAAGGAGCCACGAGTGCATCATCGACGAGGACTGTGGGCCCAGCATGTACTGCCAG
  TTTGCCAGCTTCCAGTACACCTGCCAGCCATGCCGGGGCCAGAGGATGCTCTGCACCCGG
  GACAGTGAGTGCTGTGGAGACCAGCTGTGTGTCTGGGGTCACTGCACCAAAATGGCCACC
  AGGGGCAGCAATGGGACCATCTGTGACAACCAGAGGGACTGCCAGCCGGGGCTGTGCTGT
  GCCTTCCAGAGAGGCCTGCTGTTCCCTGTGTGCACACCCCTGCCCGTGGAGGGCGAGCTT
  TGCCATGACCCCGCCAGCCGGCTTCTGGACCTCATCACCTGGGAGCTAGAGCCTGATGGA
  GCCTTGGACCGATGCCCTTGTGCCAGTGGCCTCCTCTGCCAGCCCCACAGCCACAGCCTG
  GTGTATGTGTGCAAGCCGACCTTCGTGGGGAGCCGTGACCAAGATGGGGAGATCCTGCTG
  CCCAGAGAGGTCCCCGATGAGTATGAAGTTGGCAGCTTCATGGAGGAGGTGCGCCAGGAG
  CTGGAGGACCTGGAGAGGAGCCTGACTGAAGAGATGGCGCTGAGGGAGCCTGCGGCTGCC
  GCCGCTGCACTGCTGGGAGGGGAAGAGATTTAG
  
  Clone variation with respect to NM_013253.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013253 unedited
  GNCGGCACGCGCAATTCGGCACGAGGGCTCCCTCGGGTACCGGCGCTGCCGCACCCCGCC
  GCGCTCCCGCACCCGCGGCCCGCCCACCGCGCCGCTCCCGCATCTGCACCCGCAGCCCGG
  CGGCCTCCCGGCGGGAGCGAGCAGATCCAGTCCGGCCCGCAGCGCAACTCGGTCCAGTCG
  GGGCGGCGGCTGCGGGCGCAGAGCGGAGATGCAGCGGCTTGGGGCCACCCTGCTGTGCCT
  GCTGCTGGCGGCGGCGGTCCCCACGGCCCCCGCGCCCGCTCCGACGGCGACCTCGGCTCC
  AGTCAAGCCCGGCCCGGCTCTCAGCTACCCGCAGGAGGAGGCCACCCTCAATGAGATGTT
  CCGCGAGGTTGAGGAACTGATGGAGGACACGCAGCACAAATTGCGCAGCGCGGTGGAAGA
  GATGGAGGCAGAAGAAGCTGCTGCTAAAGCATCATCAGAAGTGAACCTGGCAAACTTACC
  TCCCAGCTATCACAATGAGACCAACACAGACACGAAGGTTGGAAATAATACCATCCATGT
  GCACCGAGAAATTCACAAGATAACCAACAACCAGACTGGACAAATGGTCTTTTCAGAGAC
  AGTTATCACATCTGTGGGAGACGAAGAAGGCAGAAGGAGCCACGAGTGCATCATCGACGA
  GGACTGTGGGCCCAGCATGTACTGCCAGTTTGCCAGCTTCCAGTACACCTGCCAGCCATG
  CCGGGGGCCAGAGATGCTCTGCACCCGGGACAGTGAGTGCTGTGGAGACCAGCTGTGTGT
  CTGGGGTCACTGCACCAAATGGCCACCAGGGCAGCAATGGGCCATCTGTGACAACAGAGG
  GACTGCCAGCCCGGGCTGTGCTGTGCCTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013253 unedited
  CCCGCGGCCGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTGGCAGTTGAAGTGATTT
  ATGCTTGATTTCTAAATGCAACTTATGTTTATACATAATTTAAAACTCAAAGAAAGCATG
  CTTATACAATCATGTGCAACTTTAAACTTTAAGAACTCTGGATGAATACATGGTGGCAAC
  AGTCCATGACACCTGAAAACATCATTTGTGGAGTGGCGTAAAGTTCAGTGTTCGCAGTCG
  CATATTACAACCATGTTTCACACAGCCCTGCTCGGTTTGATTTTCTCCACGTGGTTGATA
  ATTGGCTTCAGTTGCTGCTAAGTGATTTTGCAAATTTCATTTATAATCCTCGCCCTACAA
  TTACCTAAGTACTGTTTCTGCAGGTTAACCTGTATGCTACGCTCAGTCATATACCTTTCA
  AAGTTACTTAATGCAACTGCCAAAGAGGGACAGCGTCAATATCATTGTCTTCATTAAAAG
  GACCGTTGCCCCACACTGTGAGAACACTGCTGTTCCTAACAGTAATTTACTTTTTAGAGG
  GATGTGAGAATTACTTTGACCTTAATTTCAGAAGGGCTTGCCTCAAAAGAAAATCCAATT
  CTTCTTCCTTTTGGGGGAGCCTTCTTTGGCGGCACCAAGGCCTGCTTGTGCGGGAATGGG
  ACAAACCCCTGTCCTTTATAATCCCAAACCAGAGAAACTCGGCTGGGTCCTCACTAACTG
  GGAAACTTGGCCAACCACCTGTAATTTTCACCCCTCCTAAATCCCGATGGACCAGGAAAC
  ATATACCCCCTTCCAAGTCTCTGCCGTAAGAAGGAAATAGACTTGGTAATAAAATGGTTA
  CTTGTAACAAAGGTTCAAACCAAAAACCTGCCTGTGAAAACCCACACCTCCTGCCGTGGA
  ACATATACTTCTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013253
• ORF Size: 1053 bp
• Insert Size: 2680
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013253.4, NP_037385.2
• RefSeq Size: 2755
• RefSeq ORF: 1053
• Locus ID: 27122
• Domains: dickkopf_N
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.