DKK3 (NM_013253) Human Untagged Clone

CAT#: SC320722

DKK3 (untagged)-Human dickkopf homolog 3 (Xenopus laevis) (DKK3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DKK3
• Synonyms: REIC; RIG
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013253.4 CGACGCCAAGGGGAGGGGGCTGACCTGTGCTTGGTCCACCCCAGGTAGGGGCTGAGAGAG
  GCTTGAGGTGGAAGTGGGGTCGGGCACTCTGACCTGGTCGAGGAGGGGCTAGGGTTTGAA
  CCGGGGACAGAGTCTAGGTGAGCTGGGGCTTGGGAGCTATTAGCGTAGAGGATCCGGGTT
  CGGTTGCTCTGGCGAGGGCTCCAGCATCACAGGCGGCGGCTGCGGGCGCAGAGCGGAGAT
  GCAGCGGCTTGGGGCCACCCTGCTGTGCCTGCTGCTGGCGGCGGCGGTCCCCACGGCCCC
  CGCGCCCGCTCCGACGGCGACCTCGGCTCCAGTCAAGCCCGGCCCGGCTCTCAGCTACCC
  GCAGGAGGAGGCCACCCTCAATGAGATGTTCCGCGAGGTTGAGGAACTGATGGAGGACAC
  GCAGCACAAATTGCGCAGCGCGGTGGAAGAGATGGAGGCAGAAGAAGCTGCTGCTAAAGC
  ATCATCAGAAGTGAACCTGGCAAACTTACCTCCCAGCTATCACAATGAGACCAACACAGA
  CACGAAGGTTGGAAATAATACCATCCATGTGCACCGAGAAATTCACAAGATAACCAACAA
  CCAGACTGGACAAATGGTCTTTTCAGAGACAGTTATCACATCTGTGGGAGACGAAGAAGG
  CAGAAGGAGCCACGAGTGCATCATCGACGAGGACTGTGGGCCCAGCATGTACTGCCAGTT
  TGCCAGCTTCCAGTACACCTGCCAGCCATGCCGGGGCCAGAGGATGCTCTGCACCCGGGA
  CAGTGAGTGCTGTGGAGACCAGCTGTGTGTCTGGGGTCACTGCACCAAAATGGCCACCAG
  GGGCAGCAATGGGACCATCTGTGACAACCAGAGGGACTGCCAGCCGGGGCTGTGCTGTGC
  CTTCCAGAGAGGCCTGCTGTTCCCTGTGTGCACACCCCTGCCCGTGGAGGGCGAGCTTTG
  CCATGACCCCGCCAGCCGGCTTCTGGACCTCATCACCTGGGAGCTAGAGCCTGATGGAGC
  CTTGGACCGATGCCCTTGTGCCAGTGGCCTCCTCTGCCAGCCCCACAGCCACAGCCTGGT
  GTATGTGTGCAAGCCGACCTTCGTGGGGAGCCGTGACCAAGATGGGGAGATCCTGCTGCC
  CAGAGAGGTCCCCGATGAGTATGAAGTTGGCAGCTTCATGGAGGAGGTGCGCCAGGAGCT
  GGAGGACCTGGAGAGGAGCCTGACTGAAGAGATGGCGCTGGGGGAGCCTGCGGCTGCCGC
  CGCTGCACTGCTGGGAGGGGAAGAGATTTAGATCTGGACCAGGCTGTGGGTAGATGTGCA
  ATAGAAATAGCTAATTTATTTCCCCAGGTGTGTGCTTTAGGCGTGGGCTGACCAGGCTTC
  TTCCTACATCTTCTTCCCAGTAAGTTTCCCCTCTGGCTTGACAGCATGAGGTGTTGTGCA
  TTTGTTCAGCTCCCCCAGGCTGTTCTCCAGGCTTCACAGTCTGGTGCTTGGGAGAGTCAG
  GCAGGGTTAAACTGCAGGAGCAGTTTGCCACCCCTGTCCAGATTATTGGCTGCTTTGCCT
  CTACCAGTTGGCAGACAGCCGTTTGTTCTACATGGCTTTGATAATTGTTTGAGGGGAGGA
  GATGGAAACAATGTGGAGTCTCCCTCTGATTGGTTTTGGGGAAATGTGGAGAAGAGTGCC
  CTGCTTTGCAAACATCAACCTGGCAAAAATGCAACAAATGAATTTTCCACGCAGTTCTTT
  CCATGGGCATAGGTAAGCTGTGCCTTCAGCTGTTGCAGATGAAATGTTCTGTTCACCCTG
  CATTACATGTGTTTATTCATCCAGCAGTGTTGCTCAGCTCCTACCTCTGTGCCAGGGCAG
  CATTTTCATATCCAAGATCAATTCCCTCTCTCAGCACAGCCTGGGGAGGGGGTCATTGTT
  CTCCTCGTCCATCAGGGATCTCAGAGGCTCAGAGACTGCAAGCTGCTTGCCCAAGTCACA
  CAGCTAGTGAAGACCAGAGCAGTTTCATCTGGTTGTGACTCTAAGCTCAGTGCTCTCTCC
  ACTACCCCACACCAGCCTTGGTGCCACCAAAAGTGCTCCCCAAAAGGAAGGAGAATGGGA
  TTTTTCTTTTGAGGCATGCACATCTGGAATTAAGGTCAAACTAATTCTCACATCCCTCTA
  AAAGTAAACTACTGTTAGGAACAGCAGTGTTCTCACAGTGTGGGGCAGCCGTCCTTCTAA
  TGAAGACAATGATATTGACACTGTCCCTCTTTGGCAGTTGCATTAGTAACTTTGAAAGGT
  ATATGACTGAGCGTAGCATACAGGTTAACCTGCAGAAACAGTACTTAGGTAATTGTAGGG
  CGAGGATTATAAATGAAATTTGCAAAATCACTTAGCAGCAACTGAAGACAATTATCAACC
  ACGTGGAGAAAATCAAACCGAGCAGGGCTGTGTGAAACATGGTTGTAATATGCGACTGCG
  AACACTGAACTCTACGCCACTCCACAAATGATGTTTTCAGGTGTCATGGACTGTTGCCAC
  CATGTATTCATCCAGAGTTCTTAAAGTTTAAAGTTGCACATGATTGTATAAGCATGCTTT
  CTTTGAGTTTTAAATTATGTATAAACATAAGTTGCATTTAGAAATCAAGCATAAATCACT
  TCAACTGCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013253.4 unedited
  GCGATTGTATACGACTCCTATAGGGCGGCGGGAAATCGGCACGAGGCGACGCCAAGGGGA
  GGGGGCTGACCTGTGCTTGGTCCACCCCAGGTAGGGGCTGAGAGAGGCTTGAGGTGGAAG
  TGGGGTCGGGCACTCTGACCTGGTCGAGGAGGGGCTAGGGTTTGAACCGGGGACAGAGTC
  TAGGTGAGCTGGGGCTTGGGAGCTATTAGCGTAGAGGATCCGGGTTCGGTTGCTCTGGCG
  AGGGCTCCAGCATCACAGGCGGCGGCTGCGGGCGCAGAGCGGAGATGCAGCGGCTTGGGG
  CCACCCTGCTGTGCCTGCTGCTTTTTGGTTTGCGGTCCCCACGGCCCCCGCGCCCGCTCC
  GACGGCGACCTCGGCTCCAGTCAAGCCCGGCCCGGCTCTCAGCTACCCGCAGGAGGAGGC
  CACCCTCAATGAGATGTTCCGCGAGGTTGAGGAACTGATGGAGGACACGCAGCACAAATT
  GCGCAGCGCGGTGGAAGAGATGGAGGCAGAAGAAGCTGCTGCTAAAGCATCATCAGAAGT
  GAACCTGGCAAACTTACCTCCCAGCTATCACAATGAGACCAACACAGACACGAAGGTTGG
  AAATAATACCATCCATGTGCACCGAGAAATTCACAAGATAACCAACAACCAGACTGGACA
  ATGGTCTTTTCAGAGACAGTTATCACATCTGTGGAGACGAAGAACGCAGAAAGAGCCACG
  AGTGCATCATCGACGAGGACTGTGGGCCCAGCATGTACTGCCAGTTGCCAGCTTCCATTA
  CACTGCCATCCATGCCCGGCCCAGAGGATGCTTCTGCACCGGGACAGTGGATGCCTGTGG
  AAGACAGTCTGGTGTCTTGGGTCATGCATCTAAATGTCACCAGGCAGCATGGACCATTCG
  TGACACCAAAGAACTGACACAAAGACTTGCTGCTTCGAGAGGCTGACTGATCCATGGTGA
  CATCACT
• Restriction Sites: Please inquire
• ACCN: NM_013253
• ORF Size: 1053 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_013253.4, NP_037385.2
• RefSeq Size: 2755
• RefSeq ORF: 1053
• Locus ID: 27122
• Domains: dickkopf_N
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.