RGS17 (NM_012419) Human Untagged Clone

CAT#: SC115427

RGS17 (untagged)-Human regulator of G-protein signaling 17 (RGS17)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS17
• Synonyms: hRGS17; RGS-17; RGSZ2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115427 sequence for NM_012419 edited (data generated by NextGen Sequencing)
  ATGCGAAAAAGGCAGCAGTCCCAAAATGAAGGAACACCTGCCGTGTCTCAAGCTCCTGGA
  AACCAGAGGCCCAACAACACCTGTTGCTTTTGTTGGTGCTGTTGTTGCAGCTGCTCCTGC
  CTCACTGTGAGGAATGAAGAAAGAGGGGAAAATGCGGGAAGACCCACACACACTACAAAA
  ATGGAGAGTATCCAGGTCCTAGAGGAATGCCAAAACCCCACTGCAGAGGAAGTCTTGTCC
  TGGTCTCAAAATTTTGACAAGATGATGAAGGCCCCAGCAGGAAGAAACCTTTTCAGAGAG
  TTCCTCCGAACAGAATACAGTGAAGAGAACCTACTTTTCTGGCTTGCTTGTGAAGACTTA
  AAGAAGGAGCAGAACAAAAAAGTAATTGAAGAAAAGGCTAGGATGATATATGAAGATTAC
  ATTTCTATACTATCACCAAAAGAGGTCAGTCTTGATTCTCGAGTTAGAGAGGTGATCAAT
  AGAAATCTGTTGGATCCCAATCCTCACATGTATGAAGATGCCCAACTTCAGATATATACT
  TTAATGCACAGAGATTCTTTTCCAAGGTTTTTGAACTCTCAAATTTATAAGTCATTTGTT
  GAAAGTACTGCTGGCTCTTCTTCTGAATCTTAA
  
  Clone variation with respect to NM_012419.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012419 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGCTCTCCCTCTCTCCTCG
  CCCGCTGGGTGCTGAAGTTGGGCGGATGGCAGCAAACCGGCTCCGCTAGAGGACCGAGCC
  GCCCAGCCCCGCTCCCCCGGACCCATCGGCGCGCTGCCCACACCTCCAGGCGACCGGCCA
  ACTGGGTCCTGAAGTAGCTGAAATGCGAAAAAGGCAGCAGTCCCAAAATGAAGGAACACC
  TGCCGTGTCTCAAGCTCCTGGAAACCAGAGGCCCAACAACACCTGTTGCTTTTGTTGGTG
  CTGTTGTTGCAGCTGCTCCTGCCTCACTGTGAGGAATGAAGAAAGAGGGGAAAATGCGGG
  AAGACCCACACACACTACAAAAATGGAGAGTATCCAGGTCCTAGAGGAATGCCAAAACCC
  CACTGCAGAGGAAGTCTTGTCCTGGTCTCAAAATTTTGACAAGATGATGAAGGCCCCAGC
  AGGAAGAAACCTTTTCAGAGAGTTCCTCCGAACAGAATACAGTGAAGAGAACCTACTTTT
  CTGGCTTGCTTGTGAAGACTTAAAGAAGGAGCAGAACAAAAAAGTAATTGAAGAAAAGGC
  TAGGATGATATATGAAGATTACATTTCTATACTATCACCAAAAGAGGTCAGTCTTGATTC
  TCGAGTTAGAGAGGTGATCAATAGAAATCTGTTGGATCCCAATCCTCACATGTATGAAGA
  TGCCCAACTTCAGATATATACTTTAATGCACAGAGATTCTTTTCCAAGGTTTTTGACTCT
  CAATTTATAGTCATTTGTTGAAGTACTGCTGGCTCCTCTTCTGAAATCTATGGTCATTTA
  AAACATCATTNTGGAGGCTGAGAGGGAANATAAAGTAGTAATACATCAGAACTGAGTCCT
  GGAAACTACAGTTACATTCTCAGCTCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012419 unedited
  TATGGCCCGGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTGGTTTTTGCTT
  TTAGCATAGTAAACTCTCCTGTAATGAAAATGCCACAGTTTTGGCAGTGAACAACCAGAG
  GAATCCCCATTAGGATTTTCCAACAAACAGAGATAAATAGCTCTTTTTCATGTACAGAAA
  TATTGGCTTCAAAATTAGTGTACTAAACACAGTATATAGAATGTTGAATACCATTGTTAC
  ATAGTAAAAATTGCTTTTTTTCTGTCTTAGATTATGTTAAAAAATGCAAACCATGGCCGA
  TTTTTTTGGCAATTATTTCTTAAGACCATATTGCACAAAAGTCCTTAAATACAGATATAA
  GTTATGCTACTGGATTAAATATTACAACAACTATGTGGCAAATGAAGCATTTTACTTTGC
  ACATGCAGTCTCTGGAGATACACGAGGAGACTGTTCATAGGACTACAAATACACTTTGCT
  TGCAAGTAGAATGAGTCTTGAATAAAACAAACAATTTGGCAATTCATTGTTTTGTGTGGT
  ATTTTCTCCAAACTTAACCATGGAAAACCTTGATAAAAATGGAGACAAAGACCATAACGG
  TTGTGTTTTCACAGTAGCCTGAGGAATGCTAAACTGTAGTTCTCCAGGAACTCAGTTTCT
  GATGTTATTTAACTACTTTTATTTCCCATCTCAGCCCTCCAAAATGATTGTTTTTAAATG
  AACATTAAGATTCAGAAGAAGAGCCAGCAGTACTTTCAACAAATGACTTATAAATTTGAG
  AGTTCAAAAACCTTGGGAAAGAATCTCTGTGCATTAAAGTATATATCTGAAGTTGGGCAT
  CTTCATACATGTGAAGAATGGGACCAACAGATTCTATTGATCACCTCTTAACTCGAGATC
  AAN
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_012419
• ORF Size: 633 bp
• Insert Size: 1470
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012419.4, NP_036551.3
• RefSeq Size: 1472
• RefSeq ORF: 633
• Locus ID: 26575
• Domains: RGS
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]