RGS17 (NM_012419) Human Untagged Clone

CAT#: SC323766

RGS17 (untagged)-Human regulator of G-protein signaling 17 (RGS17)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS17
• Synonyms: hRGS17; RGS-17; RGSZ2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012419.4 CTCTCCTCGCCCGCTGGGTGCTGAAGTTGGGCGGATGGCAGCAAACCGGCTCCGCTAGAG
  GACCGAGCCGCCCAGCCCCGCTCCCCCGGACCCATCGGCGCGCTGCCCACACCTCCAGGC
  GACCGGCCAACTGGGTCCTGAAGTAGCTGAAATGCGAAAAAGGCAGCAGTCCCAAAATGA
  AGGAACACCTGCCGTGTCTCAAGCTCCTGGAAACCAGAGGCCCAACAACACCTGTTGCTT
  TTGTTGGTGCTGTTGTTGCAGCTGCTCCTGCCTCACTGTGAGGAATGAAGAAAGAGGGGA
  AAATGCGGGAAGACCCACACACACTACAAAAATGGAGAGTATCCAGGTCCTAGAGGAATG
  CCAAAACCCCACTGCAGAGGAAGTCTTGTCCTGGTCTCAAAATTTTGACAAGATGATGAA
  GGCCCCAGCAGGAAGAAACCTTTTCAGAGAGTTCCTCCGAACAGAATACAGTGAAGAGAA
  CCTACTTTTCTGGCTTGCTTGTGAAGACTTAAAGAAGGAGCAGAACAAAAAAGTAATTGA
  AGAAAAGGCTAGGATGATATATGAAGATTACATTTCTATACTATCACCAAAAGAGGTCAG
  TCTTGATTCTCGAGTTAGAGAGGTGATCAATAGAAATCTGTTGGATCCCAATCCTCACAT
  GTATGAAGATGCCCAACTTCAGATATATACTTTAATGCACAGAGATTCTTTTCCAAGGTT
  TTTGAACTCTCAAATTTATAAGTCATTTGTTGAAAGTACTGCTGGCTCTTCTTCTGAATC
  TTAATGTTCATTTAAAAACAATCATTTTGGAGGGCTGAGATGGGAAATAAAAGTAGTTAA
  ATAACATCAGAAACTGAGTTCCTGGAGAACTACAGTTTAGCATTCCTCAGGCTACTGTGA
  AAACACAACCGTTATGGTCTTTGTCTCCATTTTTATCAAGGTTTTCCATGGTTAAGTTTG
  GAGAAAATACCACACAAAACAATGAATTGCCAAATTGTTTGTTTTATTCAAGACTCATTC
  TACTTGCAAGCAAAGTGTATTTGTAGTCCTATGAACAGTCTCCTCGTGTATCTCCAGAGA
  CTGCATGTGCAAAGTAAAATGCTTCATTTGCCACATAGTTGTTGTAATATTTAATCCAGT
  AGCATAACTTATATCTGTATTTAAGGACTTTTGTGCAATATGGTCTTAAGAAATAATTGC
  CAAAAAAATCGGCCATGGTTCTGCATTTTTAACATAATCTAAGACAGAAAAAAAGCAATT
  TTTACTATGTAACAATGGTATTCAACATTCTATATACTGTGTTTAGTACACTAATTTTGA
  AGCCAATATTTCTGTACATGAAAAAGAGCTATTTATCTCTGTTTGTTGGAAAATCCTAAT
  GGGGATTCCTCTGGTTGTTCACTGCCAAAACTGTGGCATTTTCATTACAGGAGAGTTTAC
  TATGCTAAAAGCAAAAAACAAAAAAAAAAAAAAAGGGAAGAAGGAAAAAAGCAAAAAACA
  ATTTGAAGATATCCTATCTCAATGACAAATCAAAAGAGTGATATTGCTTTTAACTGTAAT
  AGAAGAAAATGAATTTATGTATATATCAGATGTCCAATACTGTAATTAATTTATTAAAGA
  CTGGCTCTCCAGTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012419.4 unedited
  GACACTTTGTATACGACTCCTATAGGGCGGCCGGCGTACTCGCGGCGCGCCGGTACCGGT
  CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCTCTCCTCGCCCGCTGGGTGCTGA
  AGTTGGGCGGATGGCAGCAAACCGGCTCCGCTAGAGGACCGAGCCGCCCAGCCCCGCTCC
  CCCGGACCCATCGGCGCGCTGCCCACACCTCCAGGCGACCGGCCAACTGGGTCCTGAAGT
  AGCTGAAATGCGAAAAAGGCAGCAGTCCCAAAATGAAGGAACACCTGCCGTGTCTCAAGC
  TCCTGGAAACCAGAGGCCCAACAACACCTGTTGCTTTTGTTGGTGCTGTTGTTGCAGCTG
  CTCCTGCCTCACTGTGAGGAATGAAGAAAGAGGGGAAAATGCGGGAAGACCCACACACAC
  TACAAAAATGGAGAGTATCCAGGTCCTAGAGGAATGCCAAAACCCCACTGCAGAGGAAGT
  CTTGTCCTGGTCTCAAAATTTTGACAAGATGATGAAGGCCCCAGCAGGAAGAAACCTTTT
  CAGAGAGTTCCTCCGAACAGAATACAGTGAAGAGAACCTACTTTTCTGGCTTGCTTGTGA
  AGACTTAAAGAAGGAGCAGAACAAAAAAGTAATTGAAGAAAAGGCTAGGATGATATATGA
  AGATTACATTTCTATACTATCACCAAAAGAGGTCAGTCTTGATTCTCGAGTTAGAGAGGT
  GATCAATAGAAATCTGTTGGATCCCAATCCTCACATGTATGAAGATGCCCAACTTCAGAT
  ATATACTTTAATGCACAGAGATTCTTTTCCAAGGTTTTTGAACTCTCAATTTATAAGTCA
  TTTGTGAAAGTACTGCTGGCTTCTTCTTCTGATCTTAATGTTCATTAAAAACAATCATTT
  GGAGGCTGAATGGGAATAAAAGTAGTGATACATCGAAACTTGATTCCTGGGAGAACTACA
  GGTTAC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_012419
• ORF Size: 633 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012419.4, NP_036551.3
• RefSeq Size: 1472
• RefSeq ORF: 633
• Locus ID: 26575
• Domains: RGS
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]