Frizzled 4 (FZD4) (NM_012193) Human Untagged Clone

CAT#: SC115479

FZD4 (untagged)-Human frizzled family receptor 4 (FZD4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FZD4
• Synonyms: CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012193 edited
  GAATTCGGCACGAGGCGGACGCGGCCGGCGCCGGCTTGTGGGCTCGCCGCCTGCAGCCAT
  GACCCTCGCAGCCTGTCCCTCGGCCTCGGCCCGGGACGTCTAAAATCCCACACAGTCGCG
  CGCAGCTGCTGGAGAGCCGGCCGCTGCCCCCTCGTCGCCGCATCACACTCCCGTCCCGGG
  AGCTGGGAGCAGCGCGGGCAGCCGGCGCCCCCGTGCAAACTGGGGGTGTCTGCCAGAGCA
  GCCCCAGCCGCTGCCGCTGCTACCCCCGATGCTGGCCATGGCCTGGCGGGGCGCAGGGCC
  GAGCGTCCCGGGGGCGCCCGGGGGCGTCGGTCTCAGTCTGGGGTTGCTCCTGCAGTTGCT
  GCTGCTCCTGGGGCCGGCGCGGGGCTTCGGGGACGAGGAAGAGCGGCGCTGCGACCCCAT
  CCGCATCTCCATGTGCCAGAACCTCGGCTACAACGTGACCAAGATGCCCAACCTGGTTGG
  GCACGAGCTGCAGACGGACGCCGAGCTGCAGCTGACAACTTTCACACCGCTCATCCAGTA
  CGGCTGCTCCAGCCAGCTGCAGTTCTTCCTTTGTTCTGTTTATGTGCCAATGTGCACAGA
  GAAGATCAACATCCCCATTGGCCCATGCGGCGGCATGTGTCTTTCAGTCAAGAGACGCTG
  TGAACCCGTCCTGAAGGAATTTGGATTTGCCTGGCCAGAGAGTCTGAACTGCAGCAAATT
  CCCACCACAGAACGACCACAACCACATGTGCATGGAAGGGCCAGGTGATGAAGAGGTGCC
  CTTACCTCACAAAACCCCCATCCAGCCTGGGGAAGAGTGTCACTCTGTGGGAACCAATTC
  TGATCAGTACATCTGGGTGAAAAGGAGCCTGAACTGTGTGCTCAAGTGTGGCTATGATGC
  TGGCTTATACAGCCGCTCAGCCAAGGAGTTCACTGATATCTGGATGGCTGTGTGGGCCAG
  CCTGTGTTTCATCTCCACTGCCTTCACAGTACTGACCTTCCTGATCGATTCTTCTAGGTT
  TTCCTACCCTGAGCGCCCCATCATATTTCTCAGTATGTGCTATAATATTTATAGCATTGC
  TTATATTGTCAGGCTGACTGTAGGCCGGGAAAGGATATCCTGTGATTTTGAAGAGGCAGC
  AGAACCTGTTCTCATCCAAGAAGGACTTAAGAACACAGGATGTGCAATAATTTTCTTGCT
  GATGTACTTTTTTGGAATGGCCAGCTCCATTTGGTGGGTTATTCTGACACTCACTTGGTT
  TTTGGCAGCAGGACTCAAATGGGGTCATGAAGCCATTGAAATGCACAGCTCTTATTTCCA
  CATTGCAGCCTGGGCCATCCCCGCAGTGAAAACCATTGTCATCTTGATTATGAGACTGGT
  GGATGCAGATGAACTGACTGGCTTGTGCTATGTTGGAAACCAAAATCTCGATGCCCTCAC
  CGGGTTCGTGGTGGCTCCCCTCTTTACTTATTTGGTCATTGGAACTTTGTTCATTGCTGC
  AGGTTTGGTGGCCTTGTTCAAAATTCGGTCAAATCTTCAAAAGGATGGGACAAAGACAGA
  CAAGTTAGAAAGACTGATGGTCAAGATTGGGGTGTTCTCAGTACTGTACACAGTTCCTGC
  AACGTGTGTGATTGCCTGTTATTTTTATGAAATCTCCAACTGGGCACTTTTTCGGTATTC
  TGCAGATGATTCCAACATGGCTGTTGAAATGTTGAAAATTTTTATGTCTTTGTTGGTGGG
  CATCACTTCAGGCATGTGGATTTGGTCTGCCAAAACTCTTCACACGTGGCAGAAGTGTTC
  CAACAGATTGGTGAATTCTGGAAAGGTAAAGAGAGAGAAGAGAGGAAATGGTTGGGTGAA
  GCCTGGAAAAGGCAGTGAGACTGTGGTATAAGGCTAGTCAGCCTCCATGCTTTCTTCATT
  TTGAAGGGGGGAATGCCAGCATTTTGGAGGAAATTCTACTAAAAGTTTTATGCAGTGAAT
  CTCAGTTTGAACAAACTAGCAACAATTAAGTGACCCCCGTCAACCCACTGCCTCCCACCC
  CGACCCCAGCATCAAAAAACCAATGATTTTGCTGCAGACTTTGGAATGATCCAAAATGGA
  AAAGCCAGTTAGAGGCTTTCAAAGCTGTGAAAAATCAAAACGTTGATCACTTTAGCAGGT
  TGCAGCTTGGAGCGTGGAGGTCCTGCCTAGATTCCAGGAAGTCCAGGGCGATACTGTTTT
  CCCCTGCAGGGTGGGATTTGAGCTGTGAGTTGGTAACTAGCAGGGAGAAATATTAACTTT
  TTTAACCCTTTACCATTTTAAATACTAACTGGGTCTTTCAGATAGCAAAGCAATCTATAA
  ACACTGGAAACGCTGGGTTCAGAAAAGTGTTACAAGAGTTTTATAGTTTGGCTGATGTAA
  CATAAACATCTTCTGTGGTGCGCTGTCTGCTGTTTAGAACTTTGTGGACTGCACTCCCAA
  GAAGTGGTGTTAGAATCTTTCAGTGCCTTTGTCATAAAACAGTTATTTGAACAAACAAAA
  GTACTGTACTCACACACATAAGGTATCCAGTGGATTTTTCTTCTCTGTCTTCCTCTCTTA
  AATTTCAACATCTCTCTTCTTGGCTGCTGCTGTTTTCTTCATTTTATGTTAATGACTCAA
  AAAAGGTATTTTTATAGAATTTTTGTACTGCAGCATGCTTAAAGAGGGGAAAAGGAAGGG
  TGATTCACTTTCTGACAATCACTTAATTCAGAGGAAAATGAGATTTACTAAGTTGACTTA
  CCTGACGGACCCCAGAGACCTATTGCATTGAGCAGTGGGGACTTAATATATTTTACTTGT
  GTGATTGCATCTATGCAGACGCCAGTCTGGAAGAGCTGAAATGTTAAGTTTCTTGGCAAC
  TTTGCATTCACACAGATTAGCTGTGTAATTTTTGTGTGTCAATTACAATTAAAAGCACAT
  TGTTGGACCATGACATAGTATACTCAACTGACTTTAAAACTATGGTCAACTTCAACTTGC
  ATTCTCAGAATGATAGTGCCTTTAAAAATTTTTTTATTTTTTAAAGCATAAGAATGTTAT
  CAGAATCTGGTCTACTTAGGACAATGGAGACTTTTTCAGTTTTATAAAGGGAACTGAGGA
  CAGCTAATCCAACTACTTGGTGCGTAATTGTTTCCTAGTAATTGGCAAAGGCTCCTTGTA
  AGATTTCACTGGAGGCAGTGTGGCCTGGAGTATTTATATGGTGCTTAATGAATCTCCAGA
  ATGCCAGCCAGAAGCCTGATTGGTTAGTAGGGAATAAAGTGTAGACCATATGAAATGAAC
  TGCAAACTCTAATAGCCCAGGTCTTAATTGCCTTTAGCAGAGGTATCCAAAGCTTTTAAA
  ATTTATGCATACGTTCTTCACAAGGGGGTACCCCCAGCAGCCTCTCGAAAATTGCACTTC
  TCTTAAAACTGTAACTGGCCTTTCTCTTACCTTGCCTTAGGCCTTCTAATCATGAGATCT
  TGGGGACAAATTGACTATGTCACAGGTTGCTCTCCTTGTAACTCATACCTGTCTGCTTCA
  GCAACTGCTTTGCAATGACATTTATTTATTAATTCATGCCTTAAAAAAATAGGAAGGGAA
  GCTTTTTTTTTTCTTTTTTTTTTTTTTCAATCACACTTTGTGGAAAAACATTTCCAGGGA
  CTCAAAATTCCAAAAAGGTGGTCAAATTCTGGAAGTAAGCATTTCCTCTTTTTTAAAAAT
  TTGGTTTGAGCCTTATGCCCATAGTTTGACATTTCCCTTTCTTCTTTCCTTTTTGTTTTT
  GTGTGGTTCTTGAGCTCTCTGACATCAAGATGCATGTAAAGTCGATTGTATGTTTTGGAA
  GGCAAAGTCTTGGCTTTTGAGACTGAAGTTAAGTGGGCACAGGTGGCCCCTGCTGCTGTG
  CCCAGTCTGAGTACCTTGGCTAGACTCTAGGTCAGGCTCCAGGAGCATGAGAATTGATCC
  CCAGAAGAACCATTTTAACTCCATCTGATACTCCATTGCCTATGAAATGTAAAATGTGAA
  CTCCCTGTGCTGCTTGTAGACAGTTCCCATAACTGTCCACGGCCCTGGAGCACGCACCCA
  GGGGCAGAGCCTGCCCTTACTCACGCTCTGCTCTGGTGTCTTGGGAGTTGTGCAGGGACT
  CTGGCCCAGGCAGGGGAAGGAAGACCAGGCGGTAGGGGACTGGTCTTGCTGTTAGAGTAT
  AGAGGTTTGTAATGCAGTTTTCTTCATAATGTGTCAGTGATTGTGTGACCAAGGCAGCAT
  CTAGCAGAAAGCCAGGCATGGAGTAGGTGATCGATACTTGTCAATGACTAAATAATAACA
  ATAAAAGAGCACTTGGGTGAATCTGGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012193 unedited
  TTTCCCGCCCGTTGCCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAG
  AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA
  TTCGGCACGAGGCGGACGCGGCCGGCGCCGGCTTGTGGGCTCGCCGCCTGCAGCCATGAC
  CCTCGCAGCCTGTCCCTCGGCCTCGGCCCGGGACGTCTAAAATCCCACACAGTCGCGCGC
  AGCTGCTGGAGAGCCGGCCGCTGCCCCCTCGTCGCCGCATCACACTCCCGTCCCGGGAGC
  TGGGAGCAGCGCGGGCAGCCGGCGCCCCCGTGCAAACTGGGGGTGTCTGCCAGAGCAGCC
  CCAGCCGCTGCCGCTGCTACCCCCGATGCTGGCCATGGCCTGGCGGGGCGCAGGGCCGAG
  CGTCCCGGGGGCGCCCGGGGGCGTCGGTCTCAGTCTGGGGTTGCTCCTGCAGTTGCTGCT
  GCTCCTGGGGCCGGCGCGGGGCTTCGGGGACGAGGAAGAGCGGCGCTGCGACCCCATCCG
  CATCTCCATGTGCCAGAACCTCGGCTACAACGTGACCAAGATGCCCAACCTGGTTGGGCA
  CGAGCTGCAGACGGACGCCGAGCTGCAGCTGACAACTTTCACACCGCTCATCCAGTACGG
  CTGCTCCAGCCAGCTGCAGTTCTTCCTTTGTTCTGTTTATGTGCCAATGTGCACAGAGAA
  GATCAACATCCCCATTGGCCCATGCNGCNGCATGTGTCTTTCAGTCAAGAGACGCTGTGA
  ACCCGTCCCTGAAGAAATTGGNATTGCCTGGCCAGAGAGTCTGAACTGCAGCANATTCCC
  CACACAGAACGACCACNACCACATGTGCATGGAAGGGCCCAGTGATGAANNAGTGCCCNT
  TACTCACAAACCCCCATCCAGCCTGGGGGAAGAGTGTCACTCTGTGGGAACCAATTCTGA
  TCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012193 unedited
  CTTTTTTTCCAATCCCCAATGCTCTTTTATTGTTATTATTTAGTCATTGACAAGTATCGA
  TCACCTACTCCATGCCTGGCTTTCTGCTAGATGCTGCCTTGGTCACACAATCACTGACAC
  ATTATGAAGAAAACTGCATTACAAACCTCTATACTCTAACAGCAAGACCATTCCCCTACC
  GCCTGGTCTTCCTTCCCCTGCCTGGGCCAGAGTCCCTGCACAACTCCCAAGACACCAGAG
  CAGAGCGTGAGTAAGGGCAGGCTCTGCCCCTGGGTGCGTGCTCCAGGGCCGTGGACAGTT
  ATGGGAACTGTCTACAAGCAGCACAGGGAGTTCACATTTTACATTTCATAGGCAATGGAG
  TATCAGATGGAGTTAAAATGGTTCTTCTGGGGATCAATTCTCATGCTCCTGGAGCCTGAC
  CTAGAGTCTAGCCAAGGTACTCAGACTGGGCACAGCAGCAGGGGCCACCTGTGCCCACTT
  AACTTCAGTCTCAAAAGCCAAGACTTTGCCTTCCAAAACATACAATCGACTTTACATGCA
  TCTTGATGTCAGAGAGCTCAAGAACCACACAAAAACAAAAAGGAAAGAAGAAAGGGAAAT
  GTCAAACTATGGGCATAAGGCTCAAACCAAATTTTTAAAAAAGAGGAAATGCTTACTTCC
  AGAATTTGACCACCTTTTTGGAATTTTGAGTCCCTGGAAATGTTTTTTCACAAAGTGTGA
  TTGAAAAAAAAAAAAAAGAAAAAAAAAAGCTCCCCTTCCTATTTTTTTAAAGCATGAATT
  AATAAATAAATGTCATTGGAAAGCAATTGCTGAAACAAACAGGGTTTGAGTTACAAGGGG
  AGCAACCTGTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012193
• ORF Size: 1614 bp
• Insert Size: 4700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_012193.2, NP_036325.2
• RefSeq Size: 7391
• RefSeq ORF: 1614
• Locus ID: 8322
• Domains: FRI, Frizzled
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway
• Gene Summary: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]