NCOA62 (SNW1) (NM_012245) Human Untagged Clone

CAT#: SC115506

SNW1 (untagged)-Human SNW domain containing 1 (SNW1)


  "NM_012245" in other vectors (6)

Reconstitution Protocol

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    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SNW1
Synonyms Bx42; FUN20; NCOA-62; Prp45; PRPF45; SKIIP; SKIP; SKIP1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_012245 edited
GCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGT
AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTCGCGCTGGAAGAAGCG
GAAGAAGATGGCGCTCACCAGCTTTTTACCTGCACCTACTCAGCTATCTCAGGACCAGCT
TGAGGCTGAAGAAAAGGCAAGATCCCAGAGATCACGGCAGACCTCACTGGTCTCCTCCCG
AAGAGAACCTCCCCCGTACGGATACCGGAAAGGCTGGATACCTCGGTTATTAGAGGATTT
TGGAGATGGAGGTGCTTTTCCAGAGATCCATGTGGCCCAGTATCCACTGGATATGGGACG
AAAGAAAAAAATGTCGAATGCGCTGGCCATTCAGGTGGATTCTGAAGGAAAAATTAAATA
TGATGCAATTGCTCGACAAGGACAGTCAAAAGACAAGGTCATTTATAGCAAATACACTGA
CCTGGTTCCAAAGGAGGTTATGAATGCAGATGATCCAGACCTGCAAAGGCCCGATGAAGA
AGCTATTAAAGAGATAACAGAAAAGACAAGAGTAGCCTTAGAAAAATCTGTATCACAGAA
GGTCGCCGCAGCCATGCCAGTTCGAGCAGCTGACAAATTGGCTCCTGCTCAGTATATCCG
ATACACACCATCTCAGCAAGGAGTGGCATTCAACTCTGGAGCTAAACAGAGGGTTATTCG
GATGGTAGAAATGCAGAAAGATCCAATGGAGCCTCCAAGGTTCAAGATTAATAAGAAAAT
TCCCCGGGGACCACCTTCTCCTCCTGCGCCTGTCATGCATTCTCCTAGCCGAAAGATGAC
TGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAA
GGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGT
ACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGC
TCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGA
AAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAAAGAAGAGCTGGGAT
CAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGCATGA
CAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTC
GAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAA
TCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTAT
GGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAG
AGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACAT
GTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGGAGTT
TTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTTCAGTTTGAGGAAGATCC
TTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTC
AGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGC
ACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGG
GGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTA
CTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGTTTTT
TTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGC
CCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGT
TTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAAGATG
TTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATT
TGGAGTGGGCAAAGTAACCTCTTGCTTGGTGCAACTATTTGTTTCAAATAAAAACATTTA
GACAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCT
GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCT
>OriGene 5' read for NM_012245 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTCGCGCTGGAAGAAG
CGGAAGAAGATGGCGCTCACCAGCTTTTTACCTGCACCTACTCAGCTATCTCAGGACCAG
CTTGAGGCTGAAGAAAAGGCAAGATCCCAGAGATCACGGCAGACCTCACTGGTCTCCTCC
CGAAGAGAACCTCCCCCGTACGGATACCGGAAAGGCTGGATACCTCGGTTATTAGAGGAT
TTTGGAGATGGAGGTGCTTTTCCAGAGATCCATGTGGCCCAGTATCCACTGGATATGGGA
CGAAAGAAAAAAATGTCGAATGCGCTGGCCATTCAGGTGGATTCTGAAGGAAAAATTAAA
TATGATGCAATTGCTCGACAAGGACAGTCAAAAGACAAGGTCATTTATAGCAAATACACT
GACCTGGTTCCAAAGGAGGTTATGAATGCAGATGATCCAGACCTGCAAAGGCCCGATGAA
GAAGCTATTAAAGAGATAACAGAAAAGACAAGAGTAGCCTTAGAAAAATCTGTATCACAG
AAGGTCGCCGCAGCCATGCCAGTTCGAGCAGCTGACAAATTGGCTCCTGCTCAGTATATC
CGATACACACCATCTCAGCAAGGAGTGGCATTCAACTCTGGAGCTAAACAGAGGGTTATT
CGGATGGTAGAAATGCAGAAAGATCCAATGGAGCCTCCAAGGTTCAAGATTAATAAGAAA
ATTCCCCGGNGACCACCTTCTCCTCCTGCGCCTGTCATGCATTCTCCTAGCCGAAAATGA
CTGGTAAGGAACCAACAGAGTGGAAGAATCCTCCTTGTATTTCTACTGGAAAATGCAAAG
GTTATACANTNCATTAGACAACGTCTGCTGCTGATGGNAGAGACTACGACGTCACATAAT
GAAAATTCCCAANTGCAGAGCCTCTACTTGTGATCGAAGCTGTGAA
>OriGene 3' read for NM_012245 unedited
NNNNCCTTACTTGNNACCGCGGCCGCTTTCTAGNATCGAGTTTTTTTTTTTTTTTTTTGT
CTAAAGTTTTTATTTGAAACAAATAGTTGCACCAAGCAAGAGGTTACTTTGCCCACTCCA
AATTAAAACAGAGCACAATAGGGGCAAAATTTATTTGGCAGGACAGTTCCAGTATGTGAA
CATCTTCCTCCTCACTGTGGTTGGGGTAACTTTACTCATATGCAGCTGTTCTTACACAAA
ACATTAACCCCAAACTACTAGTGTCACATAAAAGTAAGTGGTCTTGACTTTGTATGTGGG
GCAGCATGTTCTATAAATGCTGAAAGGTGGGAGAAGCACAAACACAACCCACTCTTTAAA
AAAAACTAAATAATTCAAAGTAGAATTTTCTATCCCCCCCATTTCTCCAGTAATAAAAAG
TAGTGCTGGGATCTGGCACCCAGATTTGGTTTTTATCCTGACCATTTACAAAGTGTTCCC
CCATATGACTTGCATCATTAGGGTTATGGGTAAGAGTTCATTCACTTTGGAGAGACCTGT
GCCTATTCCTTCCTCCTCTTCTTGCCTTCATGCTCGTGTTCCTTGGGGCGGCTGCTATCT
GAGGGTCTTTTAGAGCCACCATGCTGTTTGGCTTCTTCCAAAAACTTGTCCAAACCAAAA
GGATCTTCCTCAAACTGAACTGGTCCTTCTCGGCCTCTCTGTCTACGGTCTGAACCAGAA
AACTCCTTGTCGGNAACANATCTNGTGGTCTTTATTCTGGCTTCTANGTCATCACCCTAC
ATGTTCCTTGNCCAGATTTTTACTGGGCCTATAAATACTCTGGGCCATATCTTTACCACC
TCCTCCAGCTTGATCATAAACATTATAAATTCATCTTCTCCACTGCAAANCACTGTCCAT
ACCTNGGATGGNTGAANAGCTTTGNC
Restriction Sites NotI-NotI     
ACCN NM_012245
ORF Size 1611 bp
Insert Size 2190
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_012245.2, NP_036377.1
RefSeq Size 2146
RefSeq ORF 1611
Locus ID 22938
Domains SKIP_SNW
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Notch signaling pathway, Spliceosome
Gene Summary This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.

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