AP3M1 (NM_012095) Human Untagged Clone

CAT#: SC115541

AP3M1 (untagged)-Human adaptor-related protein complex 3, mu 1 subunit (AP3M1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AP3M1
• Synonyms: RP11-178G16.4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012095, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATCCACAGTCTATTTCTCATAAACTGTTCCGGTGACATATTTCTAGAGAAGCACTGGAAGAGCGTTG
  TGAGCCAGTCTGTCTGTGATTATTTCTTTGAAGCTCAAGAGAAAGCTGCTGATGTTGAAAATGTACCACC
  TGTCATTTCAACACCTCACCACTACCTCATCAGTATCTACCGGGATAAGCTCTTCTTTGTATCTGTCATA
  CAGACCGAAGTGCCACCTCTCTTTGTAATTGAGTTCCTACATCGAGTTGCTGACACTTTTCAGGACTACT
  TTGGTGAGTGTTCAGAGGCTGCAATTAAGGATAATGTGGTCATAGTATATGAACTCTTAGAAGAAATGTT
  AGACAATGGATTTCCACTGGCTACCGAATCTAACATTTTGAAAGAATTGATTAAACCACCAACAATTCTA
  CGCTCTGTTGTCAACTCTATTACAGGCAGTAGTAATGTTGGGGACACACTCCCCACCGGGCAGCTGTCCA
  ACATACCATGGCGTCGGGCAGGGGTAAAGTACACAAACAATGAAGCCTATTTTGATGTTGTTGAAGAAAT
  AGACGCAATTATAGATAAATCAGGATCTACAGTCTTTGCAGAAATTCAGGGGGTCATTGATGCTTGCATT
  AAACTATCTGGAATGCCTGATCTCTCCCTTTCTTTCATGAACCCTAGGCTTCTGGATGATGTCAGCTTTC
  ACCCCTGCATCCGGTTCAAGCGTTGGGAATCTGAAAGAGTTTTGTCATTTATTCCTCCAGATGGAAATTT
  CCGACTCATATCATACCGTGTCAGCTCACAAAATCTAGTGGCAATACCAGTGTATGTGAAACATAGTATC
  AGCTTTAAGGAGAACAGTTCTTGCGGCAGATTTGATATAACAATTGGACCAAAGCAGAATATGGGGAAAA
  CTATTGAAGGAATTACAGTGACAGTTCACATGCCAAAAGTTGTGCTGAACATGAACCTGACACCCACACA
  AGGCAGCTATACATTTGATCCAGTCACCAAGGTACTAACATGGGATGTGGGAAAAATTACTCCACAAAAG
  CTCCCAAGTCTTAAAGGACTGGTAAATTTACAGTCTGGAGCCCCCAAACCAGAAGAGAATCCGAGCCTCA
  ACATACAGTTTAAGATCCAGCAGCTTGCTATTTCAGGCTTAAAAGTAAACCGTTTGGACATGTATGGGGA
  GAAATATAAGCCATTTAAAGGAGTCAAATACGTCACGAAAGCTGGAAAGTTCCAAGTGAGGACATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012095 unedited
  CGAATTTTGGTATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGCCGGCGCCG
  AATCACTGACTGGCACAGGTGTTGGGAAAATGATCCACAGTCTATTTCTCATAAACTGTT
  CCGGTGACATATTTCTAGAGAAGCACTGGAAGAGCGTTGTGAGCCAGTCTGTCTGTGATT
  ATTTCTTTGAAGCTCAAGAGAAAGCTGCTGATGTTGAAAATGTACCACCTGTCATTTCAA
  CACCTCACCACTACCTCATCAGTATCTACCGGGATAAGCTCTTCTTTGTATCTGTCATAC
  AGACCGAAGTGCCACCTCTCTTTGTAATTGAGTTCCTACATCGAGTTGCTGACACTTTTC
  AGGACTACTTTGGTGAGTGTTCAGAGGCTGCAATTAAGGATAATGTGGTCATAGTATATG
  AACTCTTAGAAGAAATGTTAGACAATGGATTTCCACTGGCTACCGAATCTAACATTTTGA
  AAGAATTGATTAAACCACCAACAATTCTACGCTCTGTTGTCAACTCTATTACAGGCAGTA
  GTAATGTTGGGGACACACTCCCCACCGGGCAGCTGTCCAACATACCATGGCGTCGGGCAG
  GGGTAAAGTACACAAACAATGAAGCCTATTTTGATGTTGTTGAAGAAATAGACGCAATTA
  TAGATAAATCAGGATCTACAGTCTTTGCAGAAATTCAGGGGGTCATTGATGCTTGCATTA
  AACTATCTGGAATGCCTGATCTCTCCCTTTCTTTCATGAACCCTNAGCTTCTGGATGATG
  TCAGCTTTCACCCCTGCATNCGGNTNNCAGCGTNGGGAATCTNNGAAGAGTTTGTCATTT
  ATTCCTNCAGATGAAANTNTNCGACTNCATATCATACCGTGTCAGCTCACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012095 unedited
  CTATGGCCCGGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTGGGGCTTTCATCTTTTTATTGGTAGCCCACCCCGAGCT
  TCCAAAATGATTTACTGGGTTCTAACCAATTAATAAATACCGTAATTTGATTGGAAAAGG
  AAACCTTTTACTTGGACATTTTAATAAAAATTGCTTAAGGGAAGGAGCTCCTGGCATACA
  TTTTACTTGGATAAAAAAAAAAATTGCCCCGGGGGGAAACTGGACCGTCCAAGTTTAAAT
  TGGTGAAATTAGGGATTCAACAAAAAGCAAAACAAATGGTCTCATTGTTCTTTTGAGGGA
  CCAACTCTGAAAAGTCAAAACCTTTAAAATAAAAAGCCATTGGACCCGGTAGCCCAACTT
  AGGCCAAAGGAATAAATATTTGGCAACATTTTGACTTTAACTGCCCATCTGAAAATAATT
  TCTTTAAAAATTTGGAAACTGCAAAACGTTGCCTTTTTTATTCCATGAAAGGCAGGGCCG
  GCCAAGGGAAAAAAACTGGTGAGTGGGCTCCTTGTACCAACACCAACCAACAACCCTTGA
  CAACATAAATGGGAAGAATGTAAAGGCTATCCTTAACATAAGGGAAAGACCGGTATAAAC
  TGAAAAATTGAAAGAAAATGGCGCCCCCAAGAGAATAGCCTTAATAACCAGAAGGGAACC
  TGAAGAACAAGCCCTTAAGATATTAACTTTCAAGCTTTCTCCATTTCTTGGAGGCTAATG
  AAGCAAAATAACTTGGCCCGGGCCACCCAGAAGAAAGAAGTTAATAAAAAGTCCCAATGA
  AATTGAGTGCACTAATACAACGTTGACTGACTTTCCAAAACCACGTGATCGGTAAAGATC
  TCAATGTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012095
• ORF Size: 1257 bp
• Insert Size: 3960
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012095.3, NP_036227.1
• RefSeq Size: 5144
• RefSeq ORF: 1257
• Locus ID: 26985
• Domains: Adap_comp_sub
• Protein Pathways: Lysosome
• Gene Summary: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 all encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.