AP3M1 (NM_012095) Human Untagged Clone

CAT#: SC322711

AP3M1 (untagged)-Human adaptor-related protein complex 3, mu 1 subunit (AP3M1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AP3M1
• Synonyms: RP11-178G16.4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322711 TGTTGGGGTGAGTGTGAGGGGCGGGAAATCTGTGGACTGGGGACAGCTCCAAAACCCGGG
  AGTAGGCTGAATAGCTGGGGCCCCCGACTCCGATCTGGGCTCTAGGAGCGTCTTTGGTGC
  TGTTGGCCCGGGCCTCGCTTCCCCCCCACTCCCGGCCTTCCGGGCTTTCTCGCCAGCAAG
  GCCAGAAGGGAGCGGTCCACCTGCAGCCCAGTGTTCTCAGGCGCCTGAGCCCCGGAGGTC
  AAGCTTACTGGGTTCCCCCTCTATAGTGAGCTGGAGTACAGACGGCAGGAATCTCAGTCC
  CAGGTTTCTGCTTTGGAGGACAAAACCCCAAACGGACCTGAGCAGACGTCCTGTTAGCGG
  GTGGTGCCTGGAAGAGCCTGGGGTGAGGAATGCAGTGAGAAGGGTGTTGCAGTTCTTCAG
  GAGAGAGAAAATGATCCACAGTCTATTTCTCATAAACTGTTCCGGTGACATATTTCTAGA
  GAAGCACTGGAAGAGCGTTGTGAGCCAGTCTGTCTGTGATTATTTCTTTGAAGCTCAAGA
  GAAAGCTGCTGATGTTGAAAATGTACCACCTGTCATTTCAACACCTCACCACTACCTCAT
  CAGTATCTACCGGGATAAGCTCTTCTTTGTATCTGTCATACAGACCGAAGTGCCACCTCT
  CTTTGTAATTGAGTTCCTACATCGAGTTGCTGACACTTTTCAGGACTACTTTGGTGAGTG
  TTCAGAGGCTGCAATTAAGGATAATGTGGTCATAGTATATGAACTCTTAGAAGAAATGTT
  AGACAATGGATTTCCACTGGCTACCGAATCTAACATTTTGAAAGAATTGATTAAACCACC
  AACAATTCTACGCTCTGTTGTCAACTCTATTACAGGCAGTAGTAATGTTGGGGACACACT
  CCCCACCGGGCAGCTGTCCAACATACCATGGCGTCGGGCAGGGGTAAAGTACACAAACAA
  TGAAGCCTATTTTGATGTTGTTGAAGAAATAGACGCAATTATAGATAAATCAGGATCTAC
  AGTCTTTGCAGAAATTCAGGGGGTCATTGATGCTTGCATTAAACTATCTGGAATGCCTGA
  TCTCTCCCTTTCTTTCATGAACCCTAGGCTTCTGGATGATGTCAGCTTTCACCCCTGCAT
  CCGGTTCAAGCGTTGGGAATCTGAAAGAGTTTTGTCATTTATTCCTCCAGATGGAAATTT
  CCGACTCATATCATACCGTGTCAGCTCACAAAATCTAGTGGCAATACCAGTGTATGTGAA
  ACATAGTATCAGCTTTAAGGAGAACAGTTCTTGCGGCAGATTTGATATAACAATTGGACC
  AAAGCAGAATATGGGGAAAACTATTGAAGGAATTACAGTGACAGTTCACATGCCAAAAGT
  TGTGCTGAACATGAACCTGACACCCACACAAGGCAGCTATACATTTGATCCAGTCACCAA
  GGTACTAACATGGGATGTGGGAAAAATTACTCCACAAAAGCTCCCAAGTCTTAAAGGACT
  GGTAAATTTACAGTCTGGAGCCCCCAAACCAGAAGAGAATCCGAGCCTCAACATACAGTT
  TAAGATCCAGCAGCTTGCTATTTCAGGCTTAAAAGTAAACCGTTTGGACATGTATGGGGA
  GAAATATAAGCCATTTAAAGGAGTCAAATACGTCACGAAAGCTGGAAAGTTCCAAGTGAG
  GACATGAGAAGAGGCCAAAATTCCTCAGGACCAGTTTGTTTTCCAAGTGTCATTACGATG
  TATCACTATTAGGTACCAAGTGAGTGGGAATACATATTCTAGTTAAAGCATTTGTGTCTA
  GCTACACACCGCTAACAAAGTTACTTAGTTATCAATGTAGGATTCTTAAGGAGCTTTAAG
  CTAAGGAAACCTTTTAGTGACTTAGCTTATTTTGTATCTTTTCACTTAGGAAGATTTTGG
  AGGTGATTTTTTTCCATAGGAGGATACCATCTGGCGGCTGCACATTGTAACAGTAAAGGC
  AGAAAGCTGTAGTGATAACCTCTCTCCTAAAAGAGTTAACTGGTCTCATCCAGCAGAAGC
  TATCTTAAATCTGTGATGTGTCAGGTGCAGCCAAATATCACACCTTCTGATCTTAGCCAT
  CCCAAACCAGTATCTGTCCCAAGAGAGGAAATTCCCCCCACCCCCAGAAGTTTACAGAAA
  ACTGCCTCTTCAAGTGTTTGCCTTATTCAGCTTTTCACTTGTGCCATTAAGCAAGCACTG
  TAGCAAAAGCCACTTCCACATGGCCCTGGCAGGGAGCACTGCTGCTCCATGCTCCATTCT
  CACTGTACTTGGTATTGTATTTTTTATAAATAAGATTTTTATGTAAAGCTTAGAATTTGA
  TTTACAGGGACCTTGCTGCAGTAAATACCATCTCAATTTTGTGCCACTGGTTCAGCTGTT
  AGCACAGTAAAAAAATCATTTGTATCAAAGGGGCAAATGCTTTATTAAGGTAGTAAAAGG
  GAACATTACTTCTGCTTTTAGGAAGTTACTGCAAGCACAAGCATTTGTGCTTTTAAGCAA
  ATTAAAGTAGTAAAAGAAAAACTTAAGTGAAACCTTTGCCATCTTCATGTTTTATAATAT
  AAAGCTTACCCAACACCAGTTAAGCCATGGTTAACCTAAATGCCTCATGCCCCAGTTCAG
  CAAAAGGAGGAAAATGTGCCTGCCTCACAGTCATCAGTCTTTTTAAATCTTTTTTGTTGT
  TGTTCTTAAGGGTTTGAATTTGTCTGCATTCCTTGTCTTTAGGGGAAATTCCCTTTTCAT
  ATTGTGTGCTTCCCAAAGCTATAGTCATAGATTTCTTCCAGAAACTATTGTCATAATTGT
  CACTGGAGTGCTTAAATATACGTACTATACTGACAAAATACATGGAAGTGAGTTATAATG
  AGGCAGAAACAAAATCCTCGGTAACATTGATGATACTCTACCGATCACCGTGGTTTTGGA
  AAGTCAGTCAACAGTTGTATTATTGCACTCAATTTCATTGTGACATTTTATTTAACTTCT
  TCATCTTGGTGGTCCTTGCCCAGTTATTTTGCCTCATTAGACATCAAGAAATGGAGAAAG
  ACTGAAAGTTAATATCTTAAGTGCTTGTTCTTCATGTTTCCTTCTTGTTATTTATGCTAT
  TCTCTTTGTGGCTCCATTCTTCTTTCAATCTTCTCAGCTTATAACCGTCTTTCCCTTATG
  CTAAGGATAGCCCTTACACTCATCCCATCTATGCTGTCAAGGGCTGCTGGTTGGTGCTGG
  TACAAGGAGCCCACTCAGCAGTTTTCTTACCTTTGCCTGCCCTGCCTTTCATGGAATAAG
  AAAGGCAACGTTTTGCAGCTTCCAAATTTCTGAAGAAACTAATCTCAGATTGGCAGTTAA
  AGTCAAAATGTTGCCAAATATTTATTCCTTTTGCCTAAGTTTGGCTACCCGGTTCAATTG
  CTTTTTATTTTTAATGTCTTGACTCTTCAGAGTTCGTACCTCAAAAGAACAATGAGAACA
  TTTGCTTTGCTTTCTGCTGAATCCCTAATCTCAACAATCTATACCTGGACTGTCCAGTTC
  TCCTCCTGTGCTATCTTCTCTTCTATCCAAGTAGAATGTATGCCAGGAGCTCCTTCCCTC
  TAGCAATTTCTACTAAAATGTCCAAGTAGAATGTTTCCTTTTACAATCAAATTACTGTAT
  TTATTAATTTGCTAGAATCCAGTAAATCATTTTGGTAGCTCTGGCTGTGCTATCAATAAA
  AAGATGAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322711 unedited
  GATCGATTCTAGTCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGG
  TACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGTGTTGGGGTGAGTGTGA
  GGGGCGGGAAATCTGTGGACTGGGGACAGCTCCAAAACCCGGGAGTAGGCTGAATAGCTG
  GGGCCCCCGACTCCGATCTGGGCTCTAGGAGCGTCTTTGGTGCTGTTGGCCCGGGCCTCG
  CTTCCCCCCCACTCCCGGCCTTCCGGGCTTTCTCGCCAGCAAGGCCAGAAGGGAGCGGTC
  CACCTGCAGCCCAGTGTTCTCAGGCGCCTGAGCCCCGGAGGTCAAGCTTACTGGGTTCCC
  CCTCTATAGTGAGCTGGAGTACAGACGGCAGGAATCTCAGTCCCAGGTTTCTGCTTTGGA
  GGACAAAACCCCAAACGGACCTGAGCAGACGTCCTGTTAGCGGGTGGTGCCTGGAAGAGC
  CTGGGGTGAGGAATGCAGTGAGAAGGGTGTTGCAGTTCTTCAGGAGAGAGAAAATGATCC
  ACAGTCTATTTCTCATAAACTGTTCCGGTGACATATTTCTAGAGAAGCACTGGAAGAGCG
  TTGTGAGCCAGTCTGTCTGTGATTATTTTCTTTGAAGCTCAAGAGAAAGCTGCTGATGTT
  GAAAATGTACCACCTGTCATTTCAACACCTCACCACTACCTCATCAGTATCTACCGGGAT
  AAGCTCTTCTTTGTATCTTGTCATACAGACCGAAGTGCCACCTCTCTTTGTAATTGGAGT
  TCTACATCGAGTTGCTGACACTTTTCAGGACTACTTGGTGAGTGGTTCAGAGGCTGCATT
  AAGGATATGTGGTCATAGTATATGACTCTTAAAGAGTGTAGACCATTGGAATTGCACTGC
  TACGGATCTACTTTCGAGATGATAACACAACATTCTACGCCTTGTGTGTGTCAGCTC
• Restriction Sites: Please inquire
• ACCN: NM_012095
• ORF Size: 1257 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012095.4, NP_036227.1
• RefSeq Size: 5144
• RefSeq ORF: 1257
• Locus ID: 26985
• Domains: Adap_comp_sub
• Protein Pathways: Lysosome
• Gene Summary: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 all encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.