POLG2 (NM_007215) Human Untagged Clone

CAT#: SC115638

POLG2 (untagged)-Human polymerase (DNA directed), gamma 2, accessory subunit (POLG2), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POLG2
• Synonyms: HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115638 sequence for NM_007215 edited (data generated by NextGen Sequencing)
  ATGCGCTCTCGTGTAGCCGTCAGGGCCTGCCATAAGGTCTGCAGGTGCCTGTTGTCTGGG
  TTTGGGGGTCGAGTAGATGCGGGGCAGCCGGAGCTGTTGACGGAAAGGAGTAGCCCCAAA
  GGAGGGCATGTGAAGTCGCACGCGGAGCTCGAGGGGAACGGCGAGCACCCAGAAGCCCCC
  GGGTCTGGAGAGGGAAGCGAGGCGCTGTTAGAGATCTGTCAGAGAAGGCATTTCCTAAGT
  GGAAGCAAGCAGCAGCTTAGCCGGGATTCTCTTCTGAGTGGGTGCCACCCCGGCTTCGGA
  CCCTTGGGCGTAGAGTTGCGGAAGAACCTGGCCGCAGAATGGTGGACCTCGGTGGTGGTG
  TTCAGGGAGCAGGTATTCCCGGTGGACGCCCTCCACCACAAACCAGGCCCTTTGCTACCC
  GGGGACAGTGCCTTCAGGTTAGTTTCTGCAGAAACTCTACGCGAAATCTTGCAAGACAAA
  GAGCTGAGTAAGGAACAGCTAGTAGCATTTCTTGAGAACGTATTAAAAACTTCTGGGAAA
  CTACGGGAGAACCTTCTTCACGGTGCCTTGGAACACTATGTTAATTGCCTGGATCTGGTA
  AACAAGAGGCTACCTTATGGCCTTGCTCAGATTGGAGTGTGTTTTCATCCTGTTTTTGAC
  ACTAAGCAGATACGAAATGGTGTTAAAAGTATTGGTGAGAAGACTGAAGCTTCGTTAGTA
  TGGTTTACTCCTCCGAGAACTTCAAACCAGTGGCTTGATTTCTGGTTACGTCATCGACTC
  CAGTGGTGGAGAAAGTTTGCCATGAGTCCATCTAACTTCAGCAGCAGTGACTGTCAGGAT
  GAAGAAGGCCGGAAAGGAAACAAACTTTACTACAATTTTCCCTGGGGAAAGGAGTTAATA
  GAAACCCTGTGGAACCTAGGAGATCACGAACTTTTACACATGTATCCTGGCAATGTGTCT
  AAATTACATGGCCGAGATGGACGAAAAAATGTGGTTCCTTGTGTTCTCTCTGTAAATGGG
  GACCTAGACCGAGGCATGCTGGCCTACCTCTATGATTCTTTCCAGCTGACAGAGAACTCC
  TTTACAAGAAAGAAAAATCTTCATAGAAAGGTACTTAAACTTCACCCTTGTTTAGCCCCT
  ATTAAGGTTGCTTTGGATGTAGGAAGAGGCCCCACATTGGAACTAAGACAGGTTTGTCAA
  GGGCTATTTAATGAGTTACTAGAAAATGGGATTTCTGTGTGGCCTGGTTATTTGGAAACT
  ATGCAGTCCTCATTGGAACAACTTTATTCGAAGTATGATGAAATGAGTATTCTCTTCACA
  GTTTTGGTTACTGAAACTACTTTGGAGAATGGATTAATACATCTGAGAAGCAGAGACACC
  ACAATGAAGGAAATGATGCATATATCCAAATTAAAAGACTTTTTGATTAAGTATATATCA
  TCAGCTAAGAATGTATAG
  
  Clone variation with respect to NM_007215.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007215 unedited
  GGTTCAAATATTTGTATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCTCCG
  GATTCTGTTAACGGTAGTGGTGGCTTGTTGGGATCCGTTGAGTGATGGGAGAGTGTGCTC
  TTTAACTTCGGAGAGAGATGCGCTCTCGTGTAGCCGTCAGGGCCTGCCATAAGGTCTGCA
  GGTGCCTGTTGTCTGGGTTTGGGGGTCGAGTAGATGCGGGGCAGCCGGAGCTGTTGACGG
  AAAGGAGTAGCCCCAAAGGAGGGCATGTGAAGTCGCACGCGGAGCTCGAGGGGAACGGCG
  AGCACCCAGAAGCCCCCGGGTCTGGAGAGGGAAGCGAGGCGCTGTTAGAGATCTGTCAGA
  GAAGGCATTTCCTAAGTGGAAGCAAGCAGCAGCTTAGCCGGGATTCTCTTCTGAGTGGGT
  GCCACCCCGGCTTCGGACCCTTGGGCGTAGAGTTGCGGAAGAACCTGGCCGCAGAATGGT
  GGACCTCGGTGGTGGTGTTCAGGGAGCAGGTATTCCCGGTGGACGCCCTCCACCACAAAC
  CAGGCCCTTTGCTACCCGGGGACAGTGCCTTCAGGTTAGTTTCTGCAGAAACTCTACGCG
  AAATCTTGCAAGACAAAGAGCTGAGTAAGGAACAGCTAGTAGCATTTCTTGAGAACGTAT
  TAAAAACTTCTGGGAAACTACGGGAGAACCTTCTTCACGGTGCCTTGGAACACTATGTTA
  ATTGCCTGGATCTGGNTAACAAGAGGCTACCTTATGGCCTTGCTCAGATTGGAGTGTGTT
  TTCATCCTGTTTTTGACACTAAGCAGATACGAAATGGTGTTAAAAGTATTGGTGAGAAGA
  CTGAAGCTTCGTTAGTATGGTTTACTCCTCCGAGAACTTCAACCAGTGGGCTNGATTCTG
  GTTACGTCATCGACTCCAGTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007215 unedited
  TGTACCGCGGCCCGCATTCTAGNATCGAGTTTTTTTTTTTTTTTTTTAGAGAGAANAATT
  TTATTATACAAATATAAAAATCTATACATTCTTAGCTGATGATATATACTTAATCAAAAA
  GTCTTTTAATTTGGATATATGCATCATTTCCTTCATTGTGGTGTCTCTGCTTCTCAGATG
  TATTAATCCATTCTCCAAAGTAGTTTCAGTAACCAAAACTGTGAAGAGAATACTCATTTC
  ATCATACTTCGAATAAAGTTGTTCCAATGAGGACTGCATAGTTTCCAAATAACCAGGCCA
  CACAGAAATCCCATTTTCTAGTAACTCATTAAATAGCCCTTGACAAACCTGTCTTAGTTC
  CAATGTGGGGCCTCTTCCTACATCCAAAGCAACCTTAATAGGGGCTAAACAAGGGTGAAG
  TTTAAGTACCTTTCTATGAAGATTTTTCTTTCTTGTAAAGGAGTTCTCTGTCAGCTGGAA
  AGAATCATAGAGGTAGGCCAGCATGCCTCGGTCTAGGTCCCCATTTACAGAGAGAACACA
  AGGAACCACATTTTTTCGTCCATCTCGGCCATGTAATTTAGACACATTGCCAGGATACAT
  GTGTAAAAGTTCGTGATCTCCTAGGTTCCACAGGGTTTCTATTAACTCCTTTCCCCAGGG
  AAAATTGTAGTAAAGTTTGTTTCCTTTCCCGCCTTCTTCATCCTGACAGTCACTGCTGCT
  GAAGTTAGATGGACTCATGGCAAACTTTCTCCACCACTGGAGTCGATGACGTACCCAGAA
  ATCAGCCCACTGGGTTTGAGTTCTCGGAGGAGTAAACATACTAACGAAGCTTCAGTTCTC
  TCACCCATACTCTTAACACCATTTCGTATCCTGCTAGATGTCAAAACCAGATGAAAACAC
  ACTCCATCTGAACCAGCCCTAAGTAGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007215
• ORF Size: 1458 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007215.2, NP_009146.2
• RefSeq Size: 1595
• RefSeq ORF: 1458
• Locus ID: 11232
• Domains: HGTP_anticodon
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Metabolic pathways
• Gene Summary: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions. [provided by RefSeq, Sep 2009]