TOPBP1 (NM_007027) Human Untagged Clone

CAT#: SC115748

TOPBP1 (untagged)-Human topoisomerase (DNA) II binding protein 1 (TOPBP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TOPBP1
• Synonyms: Dpb11; TOP2BP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_007027, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCAGAAATGACAAAGAACCGTTTTTTGTGAAGTTTTTAAAGTCTTCAGACAATTCCAAATGTTTTT
  TTAAAGCTCTCGAGTCCATAAAAGAATTCCAATCAGAAGAATATCTTCAGATTATTACAGAAGAAGAGGC
  ATTGAAGATAAAGGAGAATGATAGATCACTTTATATCTGTGACCCTTTTAGTGGCGTTGTCTTTGATCAC
  CTCAAAAAGCTTGGCTGCAGAATTGTTGGTCCTCAAGTAGTCATATTTTGTATGCACCACCAGCGATGTG
  TCCCAAGAGCCGAACATCCAGTTTATAATATGGTTATGTCTGATGTAACCATATCTTGTACAAGTCTGGA
  AAAAGAAAAAAGGGAAGAAGTTCATAAATATGTACAAATGATGGGCGGACGAGTATACAGAGACCTTAAT
  GTATCAGTAACTCACCTTATTGCAGGAGAAGTTGGTAGCAAAAAATATTTAGTTGCTGCAAACCTGAAGA
  AACCTATTTTGCTTCCCTCTTGGATAAAAACACTTTGGGAGAAGTCACAAGAGAAAAAAATAACTAGATA
  TACTGATATAAACATGGAAGATTTCAAGTGTCCTATTTTTCTTGGTTGCATAATCTGTGTGACTGGCTTA
  TGTGGCTTAGACAGGAAAGAAGTTCAGCAACTCACAGTTAAGCATGGAGGTCAATACATGGGACAATTGA
  AAATGAATGAATGTACACACCTCATTGTGCAAGAACCAAAAGGTCAGAAGTATGAGTGTGCCAAGAGATG
  GAATGTACACTGTGTGACCACACAGTGGTTTTTTGACAGTATTGAGAAAGGTTTTTGTCAGGATGAATCC
  ATATACAAGACAGAACCTAGACCAGAAGCAAAGACTATGCCCAATTCTTCAACTCCTACCAGCCAGATCA
  ACACAATTGATAGTCGTACTCTTTCAGATGTCAGCAATATTTCCAACATAAATGCAAGTTGCGTAAGTGA
  ATCAATATGTAATTCACTTAACAGCAAACTGGAGCCTACACTTGAAAATCTAGAAAATCTGGATGTCAGT
  GCATTTCAAGCACCTGAAGATTTATTAGATGGTTGTCGGATATATCTTTGCGGTTTTAGTGGCAGAAAGC
  TAGATAAACTGAGAAGACTTATTAACAGTGGAGGTGGAGTTCGTTTTAACCAGCTAAATGAAGATGTAAC
  TCATGTTATTGTGGGAGATTATGATGATGAATTGAAGCAGTTTTGGAATAAATCAGCCCACAGGCCTCAT
  GTAGTGGGAGCAAAGTGGTTGCTAGAGTGTTTCAGTAAAGGTTATATGCTTTCTGAAGAACCATATATCC
  ATGCTAATTACCAGCCAGTGGAAATTCCAGTTTCACATAAGCCTGAAAGTAAAGCAGCTCTTTTAAAAAA
  GAAGAACAGCAGCTTCTCTAAGAAAGACTTTGCTCCTAGTGAAAAGCATGAGCAAGCTGATGAAGATCTG
  CTCTCTCAATATGAAAATGGTAGCTCCACAGTAGTTGAGGCTAAGACGTCTGAAGCCAGGCCCTTTAATG
  ATTCTACTCATGCTGAGCCCTTGAATGATTCTACTCACATTTCTTTGCAAGAAGAAAACCAGTCTTCTGT
  CAGTCATTGTGTCCCTGATGTTTCTACAATTACTGAAGAAGGCTTATTTAGCCAAAAGAGTTTCCTTGTT
  TTGGGTTTTAGTAATGAAAATGAATCTAACATCGCAAACATCATAAAAGAAAATGCTGGGAAAATCATGT
  CCCTTCTGAGCAGAACTGTTGCGGATTATGCTGTGGTTCCTCTGCTGGGGTGTGAAGTGGAAGCCACTGT
  GGGAGAAGTTGTTACAAATACATGGCTGGTTACTTGCATAGACTATCAGACTTTGTTTGATCCAAAGTCG
  AATCCTCTCTTCACACCAGTTCCAGTAATGACAGGAATGACTCCTTTAGAGGATTGTGTTATTTCATTTA
  GCCAGTGTGCTGGAGCAGAAAAAGAGTCTTTAACATTCCTAGCAAACCTCCTTGGAGCAAGTGTTCAAGA
  ATACTTTGTTCGCAAATCCAATGCAAAGAAAGGCATGTTTGCCAGTACTCATCTTATACTGAAAGAACGT
  GGTGGCTCTAAATATGAAGCTGCAAAGAAGTGGAATTTACCTGCCGTTACTATAGCTTGGCTGTTGGAGA
  CTGCTAGAACGGGAAAGAGAGCAGACGAAAGCCATTTTCTGATTGAAAATTCAACTAAAGAAGAACGAAG
  TTTGGAAACAGAAATAACAAATGGAATCAATCTAAATTCAGATACTGCAGAGCATCCTGGCACACGCCTG
  CAAACTCACAGAAAAACCGTCGTTACACCTTTAGATATGAACCGCTTTCAGAGTAAAGCTTTCCGTGCTG
  TGGTCTCACAACATGCCAGACAGGTCGCAGCCTCCCCAGCAGTAGGACAACCACTTCAGAAGGAGCCCTC
  GTTACACCTGGATACACCATCAAAATTCCTGTCCAAGGACAAACTCTTCAAGCCTTCCTTTGATGTGAAG
  GATGCACTTGCAGCCTTGGAAACTCCAGGACGTCCCAGCCAACAGAAAAGGAAACCGAGTACGCCACTCT
  CAGAAGTTATTGTCAAAAACTTGCAACTTGCTTTGGCAAATAGCTCTCGAAATGCTGTCGCTCTTTCTGC
  CAGCCCTCAACTGAAAGAGGCCCAGTCAGAGAAGGAAGAAGCCCCAAAGCCACTTCACAAAGTAGTGGTA
  TGTGTTAGTAAAAAACTCAGTAAGAAGCAGAGTGAACTAAATGGGATCGCAGCCTCTCTAGGAGCAGATT
  ACAGGTGGAGTTTTGATGAAACAGTGACTCATTTCATCTATCAAGGGCGGCCAAATGACACTAATCGGGA
  GTATAAATCTGTAAAAGAAAGAGGAGTACACATTGTTTCCGAGCACTGGCTTTTAGATTGTGCCCAAGAG
  TGTAAACATCTTCCTGAATCTCTTTATCCACATACTTATAATCCCAAAATGAGCTTGGATATCAGCGCAG
  TGCAAGATGGCCGGCTCTGTAATAGTCGACTACTCTCAGCTGTGTCTTCAACAAAGGATGATGAGCCAGA
  TCCTTTGATTTTAGAAGAAAATGATGTAGACAATATGGCCACCAATAATAAAGAGTCAGCACCATCAAAT
  GGAAGTGGAAAGAATGACTCTAAAGGAGTTCTGACACAGACCTTAGAGATGAGAGAGAACTTTCAGAAGC
  AGTTACAGGAGATAATGTCTGCAACATCAATAGTGAAACCCCAAGGGCAGAGGACTTCCCTTTCAAGAAG
  TGGTTGTAACAGCGCATCTTCAACCCCTGACAGCACTCGCTCTGCTCGCAGTGGACGAAGTAGAGTCCTA
  GAGGCACTGAGGCAGTCTCGTCAGACAGTACCTGATGTCAACACAGAGCCTTCCCAAAATGAACAGATCA
  TTTGGGATGACCCTACAGCAAGGGAGGAGAGAGCAAGGCTTGCCAGCAATTTGCAGTGGCCTAGTTGTCC
  CACACAATACTCTGAGCTTCAGGTTGACATTCAAAACTTGGAGGATTCTCCTTTTCAAAAGCCTTTACAT
  GATTCAGAAATTGCTAAACAGGCTGTCTGTGATCCTGGAAACATACGTGTGACTGAAGCTCCCAAACACC
  CAATCTCTGAAGAACTGGAAACTCCCATAAAAGACAGCCACCTGATCCCTACGCCTCAAGCCCCCAGTAT
  TGCCTTTCCACTCGCCAACCCCCCTGTGGCTCCGCACCCTAGAGAAAAGATTATAACGATAGAGGAGACT
  CATGAAGAATTAAAAAAACAGTACATATTTCAGTTATCATCTCTGAATCCTCAAGAACGTATTGACTATT
  GTCATCTGATTGAGAAACTAGGTGGATTGGTGATAGAAAAGCAGTGCTTTGATCCCACCTGTACACACAT
  TGTTGTGGGACATCCACTTCGAAACGAGAAGTATTTAGCCTCAGTGGCAGCTGGGAAGTGGGTGCTTCAT
  CGCTCCTACCTTGAAGCCTGCAGGACTGCTGGACACTTCGTGCAGGAAGAAGACTATGAATGGGGAAGTA
  GTTCCATACTTGATGTTCTGACTGGAATCAATGTACAGCAACGAAGACTAGCACTTGCAGCAATGAGATG
  GAGAAAAAAAATCCAGCAAAGACAAGAATCTGGCATTGTTGAGGGAGCATTTAGTGGGTGGAAGGTTATT
  TTACATGTGGATCAGTCTCGAGAAGCAGGCTTCAAACGCCTTCTTCAGTCAGGAGGAGCAAAGGTGCTAC
  CTGGTCATTCTGTACCTTTATTTAAAGAGGCCACACATCTTTTTTCTGACTTGAATAAACTGAAACCAGA
  TGACTCAGGAGTTAATATAGCAGAAGCTGCTGCCCAGAACGTGTACTGCTTGAGAACAGAATACATTGCT
  GATTATCTCATGCAGGAATCACCTCCTCATGTAGAAAATTACTGTCTACCAGAAGCTATTTCATTTATTC
  AGAATAATAAGGAACTTGGGACTGGATTATCACAAAAGAGGAAAGCTCCTACAGAAAAAAATAAAATCAA
  ACGACCTAGAGTACACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007027 unedited
  TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCGACCCCAGCCACCGC
  CCTGCGGCCAGCGCGTCCCCCGACTCGCCGCCCGGAGACCCCGAGGCTCCAACGAGTTCA
  GAAATGTCCAGAAATGACAAAGAACCGTTTTTTGTGAAGTTTTTAAAGTCTTCAGACAAT
  TCCAAATGTTTTTTTAAAGCTCTCGAGTCCATAAAAGAATTCCAATCAGAAGAATATCTT
  CAGATTATTACAGAAGAAGAGGCATTGAAGATAAAGGAGAATGATAGATCACTTTATATC
  TGTGACCCTTTTAGTGGCGTTGTCTTTGATCACCTCAAAAAGCTTGGCTGCAGAATTGTT
  GGTCCTCAAGTAGTCATATTTTGTATGCACCACCAGCGATGTGTCCCAAGAGCCGAACAT
  CCAGTTTATAATATGGTTATGTCTGATGTAACCATATCTTGTACAAGTCTGGAAAAAGAA
  AAAAGGGAAGAAGTTCATAAATATGTACAAATGATGGGCGGACGAGTATACAGAGACCTT
  AATGTATCAGTAACTCACCTTATTGCAGGAGAAGTTGGTAGCAAAAAATATTTAGTTGCT
  GCAAACCTGAAGAAACCTATTTTGCTTCCCTCTTGGATAAAAACACTTTGGGAGAAGTCA
  CAAGAGAANAAAATACTAGATATACTGATATAAACATGGAAGATNTCAAGTGTCCTATNT
  TTCTTTGGTTGCATTAATCTGTGTGACTGGCTTATGTGGCTTAGACAGGAAAGAAGTCAG
  CAACTCACAGNTAAGCATGNGAGTCAATACATGGGGACAATTGANAAATGATGAATGTAC
  ACACCTCATTGTGCNAGAACCAAAGGTCANAGTATGAGTGTGCCAGAGATGAATGACACT
  GTGTGACCCCCAGTGGTTTTTGACGTATGAAAAGGTTTTGTAAGAAGAATCTTACAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007027
• ORF Size: 4308 bp
• Insert Size: 3000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_007027.2, NP_008958.1
• RefSeq Size: 5378
• RefSeq ORF: 4308
• Locus ID: 11073
• Domains: BRCT
• Gene Summary: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]