TOPBP1 (NM_007027) Human Untagged Clone

CAT#: SC328077

TOPBP1 (untagged)-Human topoisomerase (DNA) II binding protein 1 (TOPBP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TOPBP1
• Synonyms: Dpb11; TOP2BP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_007027, the custom clone sequence may differ by one or more nucleotides
  ATGTCCAGAAATGACAAAGAACCGTTTTTTGTGAAGTTTTTAAAGTCTTCAGACAATTCC
  AAATGTTTTTTTAAAGCTCTCGAGTCCATAAAAGAATTCCAATCAGAAGAATATCTTCAG
  ATTATTACAGAAGAAGAGGCATTGAAGATAAAGGAGAATGATAGATCACTTTATATCTGT
  GACCCTTTTAGTGGCGTTGTCTTTGATCACCTCAAAAAGCTTGGCTGCAGAATTGTTGGT
  CCTCAAGTAGTCATATTTTGTATGCACCACCAGCGATGTGTCCCAAGAGCCGAACATCCA
  GTTTATAATATGGTTATGTCTGATGTAACCATATCTTGTACAAGTCTGGAAAAAGAAAAA
  AGGGAAGAAGTTCATAAATATGTACAAATGATGGGCGGACGAGTATACAGAGACCTTAAT
  GTATCAGTAACTCACCTTATTGCAGGAGAAGTTGGTAGCAAAAAATATTTAGTTGCTGCA
  AACCTGAAGAAACCTATTTTGCTTCCCTCTTGGATAAAAACACTTTGGGAGAAGTCACAA
  GAGAAAAAAATAACTAGATATACTGATATAAACATGGAAGATTTCAAGTGTCCTATTTTT
  CTTGGTTGCATAATCTGTGTGACTGGCTTATGTGGCTTAGACAGGAAAGAAGTTCAGCAA
  CTCACAGTTAAGCATGGAGGTCAATACATGGGACAATTGAAAATGAATGAATGTACACAC
  CTCATTGTGCAAGAACCAAAAGGTCAGAAGTATGAGTGTGCCAAGAGATGGAATGTACAC
  TGTGTGACCACACAGTGGTTTTTTGACAGTATTGAGAAAGGTTTTTGTCAGGATGAATCC
  ATATACAAGACAGAACCTAGACCAGAAGCAAAGACTATGCCCAATTCTTCAACTCCTACC
  AGCCAGATCAACACAATTGATAGTCGTACTCTTTCAGATGTCAGCAATATTTCCAACATA
  AATGCAAGTTGCGTAAGTGAATCAATATGTAATTCACTTAACAGCAAACTGGAGCCTACA
  CTTGAAAATCTAGAAAATCTGGATGTCAGTGCATTTCAAGCACCTGAAGATTTATTAGAT
  GGTTGTCGGATATATCTTTGCGGTTTTAGTGGCAGAAAGCTAGATAAACTGAGAAGACTT
  ATTAACAGTGGAGGTGGAGTTCGTTTTAACCAGCTAAATGAAGATGTAACTCATGTTATT
  GTGGGAGATTATGATGATGAATTGAAGCAGTTTTGGAATAAATCAGCCCACAGGCCTCAT
  GTAGTGGGAGCAAAGTGGTTGCTAGAGTGTTTCAGTAAAGGTTATATGCTTTCTGAAGAA
  CCATATATCCATGCTAATTACCAGCCAGTGGAAATTCCAGTTTCACATAAGCCTGAAAGT
  AAAGCAGCTCTTTTAAAAAAGAAGAACAGCAGCTTCTCTAAGAAAGACTTTGCTCCTAGT
  GAAAAGCATGAGCAAGCTGATGAAGATCTGCTCTCTCAATATGAAAATGGTAGCTCCACA
  GTAGTTGAGGCTAAGACGTCTGAAGCCAGGCCCTTTAATGATTCTACTCATGCTGAGCCC
  TTGAATGATTCTACTCACATTTCTTTGCAAGAAGAAAACCAGTCTTCTGTCAGTCATTGT
  GTCCCTGATGTTTCTACAATTACTGAAGAAGGCTTATTTAGCCAAAAGAGTTTCCTTGTT
  TTGGGTTTTAGTAATGAAAATGAATCTAACATCGCAAACATCATAAAAGAAAATGCTGGG
  AAAATCATGTCCCTTCTGAGCAGAACTGTTGCGGATTATGCTGTGGTTCCTCTGCTGGGG
  TGTGAAGTGGAAGCCACTGTGGGAGAAGTTGTTACAAATACATGGCTGGTTACTTGCATA
  GACTATCAGACTTTGTTTGATCCAAAGTCGAATCCTCTCTTCACACCAGTTCCAGTAATG
  ACAGGAATGACTCCTTTAGAGGATTGTGTTATTTCATTTAGCCAGTGTGCTGGAGCAGAA
  AAAGAGTCTTTAACATTCCTAGCAAACCTCCTTGGAGCAAGTGTTCAAGAATACTTTGTT
  CGCAAATCCAATGCAAAGAAAGGCATGTTTGCCAGTACTCATCTTATACTGAAAGAACGT
  GGTGGCTCTAAATATGAAGCTGCAAAGAAGTGGAATTTACCTGCCGTTACTATAGCTTGG
  CTGTTGGAGACTGCTAGAACGGGAAAGAGAGCAGACGAAAGCCATTTTCTGATTGAAAAT
  TCAACTAAAGAAGAACGAAGTTTGGAAACAGAAATAACAAATGGAATCAATCTAAATTCA
  GATACTGCAGAGCATCCTGGCACACGCCTGCAAACTCACAGAAAAACCGTCGTTACACCT
  TTAGATATGAACCGCTTTCAGAGTAAAGCTTTCCGTGCTGTGGTCTCACAACATGCCAGA
  CAGGTCGCAGCCTCCCCAGCAGTAGGACAACCACTTCAGAAGGAGCCCTCGTTACACCTG
  GATACACCATCAAAATTCCTGTCCAAGGACAAACTCTTCAAGCCTTCCTTTGATGTGAAG
  GATGCACTTGCAGCCTTGGAAACTCCAGGACGTCCCAGCCAACAGAAAAGGAAACCGAGT
  ACGCCACTCTCAGAAGTTATTGTCAAAAACTTGCAACTTGCTTTGGCAAATAGCTCTCGA
  AATGCTGTCGCTCTTTCTGCCAGCCCTCAACTGAAAGAGGCCCAGTCAGAGAAGGAAGAA
  GCCCCAAAGCCACTTCACAAAGTAGTGGTATGTGTTAGTAAAAAACTCAGTAAGAAGCAG
  AGTGAACTAAATGGGATCGCAGCCTCTCTAGGAGCAGATTACAGGTGGAGTTTTGATGAA
  ACAGTGACTCATTTCATCTATCAAGGGCGGCCAAATGACACTAATCGGGAGTATAAATCT
  GTAAAAGAAAGAGGAGTACACATTGTTTCCGAGCACTGGCTTTTAGATTGTGCCCAAGAG
  TGTAAACATCTTCCTGAATCTCTTTATCCACATACTTATAATCCCAAAATGAGCTTGGAT
  ATCAGCGCAGTGCAAGATGGCCGGCTCTGTAATAGTCGACTACTCTCAGCTGTGTCTTCA
  ACAAAGGATGATGAGCCAGATCCTTTGATTTTAGAAGAAAATGATGTAGACAATATGGCC
  ACCAATAATAAAGAGTCAGCACCATCAAATGGAAGTGGAAAGAATGACTCTAAAGGAGTT
  CTGACACAGACCTTAGAGATGAGAGAGAACTTTCAGAAGCAGTTACAGGAGATAATGTCT
  GCAACATCAATAGTGAAACCCCAAGGGCAGAGGACTTCCCTTTCAAGAAGTGGTTGTAAC
  AGCGCATCTTCAACCCCTGACAGCACTCGCTCTGCTCGCAGTGGACGAAGTAGAGTCCTA
  GAGGCACTGAGGCAGTCTCGTCAGACAGTACCTGATGTCAACACAGAGCCTTCCCAAAAT
  GAACAGATCATTTGGGATGACCCTACAGCAAGGGAGGAGAGAGCAAGGCTTGCCAGCAAT
  TTGCAGTGGCCTAGTTGTCCCACACAATACTCTGAGCTTCAGGTTGACATTCAAAACTTG
  GAGGATTCTCCTTTTCAAAAGCCTTTACATGATTCAGAAATTGCTAAACAGGCTGTCTGT
  GATCCTGGAAACATACGTGTGACTGAAGCTCCCAAACACCCAATCTCTGAAGAACTGGAA
  ACTCCCATAAAAGACAGCCACCTGATCCCTACGCCTCAAGCCCCCAGTATTGCCTTTCCA
  CTCGCCAACCCCCCTGTGGCTCCGCACCCTAGAGAAAAGATTATAACGATAGAGGAGACT
  CATGAAGAATTAAAAAAACAGTACATATTTCAGTTATCATCTCTGAATCCTCAAGAACGT
  ATTGACTATTGTCATCTGATTGAGAAACTAGGTGGATTGGTGATAGAAAAGCAGTGCTTT
  GATCCCACCTGTACACACATTGTTGTGGGACATCCACTTCGAAACGAGAAGTATTTAGCC
  TCAGTGGCAGCTGGGAAGTGGGTGCTTCATCGCTCCTACCTTGAAGCCTGCAGGACTGCT
  GGACACTTCGTGCAGGAAGAAGACTATGAATGGGGAAGTAGTTCCATACTTGATGTTCTG
  ACTGGAATCAATGTACAGCAACGAAGACTAGCACTTGCAGCAATGAGATGGAGAAAAAAA
  ATCCAGCAAAGACAAGAATCTGGCATTGTTGAGGGAGCATTTAGTGGGTGGAAGGTTATT
  TTACATGTGGATCAGTCTCGAGAAGCAGGCTTCAAACGCCTTCTTCAGTCAGGAGGAGCA
  AAGGTGCTACCTGGTCATTCTGTACCTTTATTTAAAGAGGCCACACATCTTTTTTCTGAC
  TTGAATAAACTGAAACCAGATGACTCAGGAGTTAATATAGCAGAAGCTGCTGCCCAGAAC
  GTGTACTGCTTGAGAACAGAATACATTGCTGATTATCTCATGCAGGAATCACCTCCTCAT
  GTAGAAAATTACTGTCTACCAGAAGCTATTTCATTTATTCAGAATAATAAGGAACTTGGG
  ACTGGATTATCACAAAAGAGGAAAGCTCCTACAGAAAAAAATAAAATCAAACGACCTAGA
  GTACAC
  
• Restriction Sites: Please inquire
• ACCN: NM_007027
• ORF Size: 4569 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007027.3, NP_008958.2
• RefSeq Size: 5378
• RefSeq ORF: 4569
• Locus ID: 11073
• Domains: BRCT
• Gene Summary: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]