MAGED1 (NM_006986) Human Untagged Clone

CAT#: SC115762

MAGED1 (untagged)-Human melanoma antigen family D, 1 (MAGED1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAGED1
• Synonyms: DLXIN-1; NRAGE
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115762 sequence for NM_006986 edited (data generated by NextGen Sequencing)
  ATGGCTCAGAAAATGGACTGTGGTGCGGGCCTCCTCGGCTTCCAGGCTGAGGCCTCCGTA
  GAAGACAGCGCCTTGCTTATGCAGACCTTGATGGAGGCCATCCAGATCTCAGAGGCTCCA
  CCTACTAACCAGGCCACCGCAGCTGCTAGTCCCCAGAGTTCACAGCCCCCAACTGCCAAT
  GAGATGGCTGACATTCAGGTTTCAGCAGCTGCCGCTAGGCCTAAGTCAGCCTTTAAAGTC
  CAGAATGCCACCACAAAAGGCCCAAATGGTGTCTATGATTTCTCTCAGGCTCATAATGCC
  AAGGATGTGCCCAACACGCAGCCCAAGGCAGCCTTTAAGTCCCAAAATGCTACCCCAAAG
  GGTCCAAATGCTGCCTATGATTTTTCCCAGGCAGCAACCACTGGTGAGTTAGCTGCTAAC
  AAGTCTGAGATGGCCTTCAAGGCCCAGAATGCCACTACTAAAGTGGGCCCAAATGCCACC
  TACAATTTCTCTCAGTCTCTCAATGCCAATGACCTGGCCAACAGCAGGCCTAAGACCCCT
  TTCAAGGCTTGGAATGATACCACTAAGGCCCCAACAGCTGATACCCAGACCCAGAATGTA
  AATCAGGCCAAAATGGCCACTTCCCAGGCTGACATAGAGACCGACCCAGGTATCTCTGAA
  CCTGACGGTGCAACTGCACAGACATCAGCAGATGGTTCCCAGGCTCAGAATCTGGAGTCC
  CGGACAATAATTCGGGGCAAGAGGACCCGCAAGATTAATAACTTGAATGTTGAAGAGAAC
  AGCAGTGGGGATCAGAGGCGGGCCCCACTGGCTGCAGGGACCTGGAGGTCTGCACCAGTT
  CCAGTGACCACTCAGAACCCACCTGGCGCACCCCCCAATGTGCTCTGGCAGACGCCATTG
  GCTTGGCAGAACCCCTCAGGCTGGCAAAACCAGACAGCCAGGCAGACCCCACCAGCACGT
  CAGAGCCCTCCAGCTAGGCAGACCCCACCAGCCTGGCAGAACCCAGTCGCTTGGCAGAAC
  CCAGTGATTTGGCCAAACCCAGTAATCTGGCAGAACCCAGTGATCTGGCCAAACCCCATT
  GTCTGGCCCGGCCCTGTTGTCTGGCCGAATCCACTGGCCTGGCAGAATCCACCTGGATGG
  CAGACTCCACCTGGATGGCAGACCCCACCGGGCTGGCAGGGTCCTCCAGACTGGCAAGGT
  CCTCCTGACTGGCCGCTACCACCCGACTGGCCACTGCCACCTGATTGGCCACTTCCCACT
  GACTGGCCACTACCACCTGACTGGATCCCCGCTGATTGGCCAATTCCACCTGACTGGCAG
  AACCTGCGCCCCTCGCCTAACCTGCGCCCTTCTCCCAACTCGCGTGCCTCACAGAACCCA
  GGTGCTGCACAGCCCCGAGATGTGGCCCTTCTTCAGGAAAGAGCAAATAAGTTGGTCAAG
  TACTTGATGCTTAAGGACTACACAAAGGTGCCCATCAAGCGCTCAGAAATGCTGAGAGAT
  ATCATCCGTGAATACACTGATGTTTATCCAGAAATCATTGAACGTGCATGCTTTGTCCTA
  GAGAAGAAATTTGGGATTCAACTGAAAGAAATTGACAAAGAAGAACACCTGTATATTCTC
  ATCAGTACCCCCGAGTCCCTGGCTGGCATACTGGGAACGACCAAAGACACACCCAAGCTC
  GGTCTCCTCTTGGTGATTCTGGGTGTCATCTTCATGAATGGCAACCGTGCCAGTGAGGCT
  GTCCTCTGGGAGGCACTACGCAAGATGGGACTGCGTCCTGGGGTGAGACATCCCCTCCTT
  GGAGATCTAAGGAAACTTCTCACCTATGAGTTTGTAAAGCAGAAATACCTGGACTACAGA
  CGAGTGCCCAACAGCAACCCCCCGGAGTATGAGTTCCTCTGGGGCCTCCGTTCCTACCAT
  GAGACTAGCAAGATGAAAGTGCTGAGATTCATTGCAGAGGTTCAGAAAAGAGACCCTCGT
  GACTGGACTGCACAGTTCATGGAGGCTGCAGATGAGGCCTTGGATGCTCTGGATGCTGCT
  GCAGCTGAGGCCGAAGCCCGGGCTGAAGCAAGAACCCGCATGGGAATTGGAGATGAGGCT
  GTGTCTGGGCCCTGGAGCTGGGATGACATTGAGTTTGAGCTGCTGACCTGGGATGAGGAA
  GGAGATTTTGGAGATCCCTGGTCCAGAATTCCATTTACCTTCTGGGCCAGATACCACCAG
  AATGCCCGCTCCAGATTCCCTCAGACCTTTGCCGGTCCCATTATTGGTCCTGGTGGTACA
  GCCAGTGCCAACTTCGCTGCCAACTTTGGTGCCATTGGTTTCTTCTGGGTTGAGTGA
  
  Clone variation with respect to NM_006986.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006986 unedited
  TGTACGAATTTTGTNATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGGAGA
  GAGTGCGGCTGCTGAGAGCCGAGCCCAGCAATCCCGATCCTCTGAGTCGTGAAGAAGGGA
  GGCAGCGAGGGGGTTGGGGTTGGGGCCTGAGGCAAGCCCCCAGGCTCCGCTCTTGCCAGA
  GGGACAGGAGCCATGGCTCAGAAAATGGACTGTGGTGCGGGCCTCCTCGGCTTCCAGGCT
  GAGGCCTCCGTAGAAGACAGCGCCTTGCTTATGCAGACCTTGATGGAGGCCATCCAGATC
  TCAGAGGCTCCACCTACTAACCAGGCCACCGCAGCTGCTAGTCCCCAGAGTTCACAGCCC
  CCAACTGCCAATGAGATGGCTGACATTCAGGTTTCAGCAGCTGCCGCTAGGCCTAAGTCA
  GCCTTTAAAGTCCAGAATGCCACCACAAAAGGCCCAAATGGTGTCTATGATTTCTCTCAG
  GCTCATAATGCCAAGGATGTGCCCAACACGCAGCCCAAGGCAGCCTTTAAGTCCCAAAAT
  GCTACCCCAAAGGGTCCAAATGCTGCCTATGATTTTTCCCAGGCAGCAACCACTGGTGAG
  TTAGCTGCTAACAAGTCTGAGATGGCCTTCAAGGCCCAGAATGCCACTACTAAAGTGGGC
  CCAAATGCCACCTACAATTTCTCTCAGTCTCTCAATGCCAATGACCCTGCCAACAGCAGG
  CCTAAGACCCCTTTCAGGCTTGGAATGATACCACTAAGGCCCCCACAGCTGATACCCAGA
  CCCAGAATGGTAATCAGGCCANAATGGCCACTTCCCCAGCTGACATAGAGACCGACCCAC
  GTATCTCTGCCCCGGGACCGTGCCACTGCACAGACCTCAGCAGAATGGGTCCCAGGCTCA
  AATTCTGGAGTCCCGGCACATTATTCGGGCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006986 unedited
  AAGCTTGGACCCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTCACTTTGCAATTTCAATGTTTATTTCTGATACCAAAACTTGACAGCACACAAGGGGA
  AAAAAAAGCAGTAAACAAGGAACAGCAAATAAATTTATCTTGCATGCCACTTTCAGTCAA
  CAGGATGGGGCTCTCTAAATAGCTGGGTTTAAAAGGAATCTGAGGCTTCAGCCTCACACA
  GGGGAAAAGACTACTGCGATTGATAGCAATATCCAACATCTCACTCAACCCAAAAAAAAC
  CAATGGCACCAAAGTTGGCAGCGAAGTTGGCACTGGCTGTACCACCAGGACCAATAATGG
  GACCGGCAAAGGTCTGAGGGAATCTGGAGCGGGCATTCTGGGGGTATCTGGCCCAAAAGG
  TAAATGGAATTCTGGACCAGGGATCTCCAAAATCTCCTTCCTCATCCCAGGTCAGCAGCT
  CAAACTCAATGTCATCCCAGCTCCAGGGCCCAAACACAGCCTCATCTCCAATTCCCATGC
  GGGTTCTTGCTTCAGCCCGGGCTTCGGCCTCAGCTGCAGCAGCATCCAAAGCATCCAAGG
  CCTCATCTGCAGCCTCCATGAACTGTGCAGTCCAGTCACGAGGGTCTCTTTTCTGAACCT
  CTGCAATGAATCTCAGCACTTTCATCTTGCTAGTCTCATGGAAGGAACGGAGGCCCCAGA
  GGAACTCATACTCCGGGGGGTTGCTGTTGGGCACTCGTCTGTAGTCCAGGTATTTCTGCT
  TTACAACTCATAGGTGAGAAAGTTCCTTAGATCTCCAAGGAGGGGATGTCTCACCCCAGA
  ACGCAGTCCCATCTTGCGTAGTGCCTCCCAGAGCACACCTNACTGGCACGGTTGCCATTC
  ATGAGATGACACCCANATCCACCAGAGAGACCGGCTGGNNTTGCCTTTGGTCGTCCCANA
  TGCAGCCAGGACTCGGGTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006986
• ORF Size: 2337 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006986.3, NP_008917.3
• RefSeq Size: 2760
• RefSeq ORF: 2337
• Locus ID: 9500
• Domains: MAGE
• Protein Families: Druggable Genome
• Protein Pathways: Neurotrophin signaling pathway
• Gene Summary: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame coding exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode isoform b.