TLK2 (NM_006852) Human Untagged Clone

CAT#: SC115810

TLK2 (untagged)-Human tousled-like kinase 2 (TLK2), transcript variant A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TLK2
• Synonyms: HsHPK; MRD57; PKU-ALPHA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006852 edited
  ATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTT
  ACTGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGC
  AGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAG
  CGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGG
  GGACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGCGCCAGGAACCAGCCCT
  GGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTA
  CCGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACG
  GAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGAC
  ACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAA
  AACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAG
  ATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTA
  GAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGA
  GCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAG
  GAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAA
  GAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACT
  ACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAAT
  CTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAA
  ATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAG
  AAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATAC
  CATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAG
  ATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAA
  AGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATAT
  TTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTA
  ACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAG
  AAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGAT
  CATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACA
  GTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATG
  TCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAAT
  GAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAAT
  GGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGAT
  GATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGG
  TATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTT
  GATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGC
  CATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTG
  CAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTG
  GCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTG
  CCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACC
  TCTGGGGCGTCCAATAACAGTTCTTCTAATTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006852 unedited
  CACATTTTGTATACGACTCATATAGGCGGCCGCGAATTCGGCACGAGGCGGCAGCAGAAT
  GATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTAC
  TGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAG
  CGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCG
  AAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGG
  ACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGCGCCAGGAACCAGCCCTGG
  CAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACC
  GCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGA
  GGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACAC
  AGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAA
  CAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGAT
  CTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGA
  AAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATNTATTAAGAGC
  CAACTGTGATTTGAGACGGCAGATTGATGAACAGCANAAGATGCTAGAGAAATACAGGNA
  ACGNATAAATAGATGTGTGACAAATGAGCAGAAACTCCTTATAGAAAAGTCAAAACAAGA
  GAAAGAGGNCGTGTAGAGAATAGAAGCATGCAAACCGCTTGAGACTGGGCCACTTTACTA
  CTGTCCGACACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006852 unedited
  CGCGGCCGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGCATGGACAGATGAACCTT
  TATTTAAAAAAAAGCACTTCAAATAAATTAAAAGGGACAACCGTCAAGTGTTCAAATTGT
  GAAGAAATAGTTGAAAACCTAGAGAGACTCCAAGCTGCAGTCTTCTAACCTCATTCTTTG
  TCCAATGGCAAAAACCCACACATCTCAGTACTCCCACTCAATTTTTTCCCTACTGAGATG
  AGGGAAGCAATTGCAAACAGGAGACCAGACGGAGGAGAAAGCTGCATCTGATTGGAATGA
  ACATTGCCACGTACTTGCTAATACGGGTTTCACTTTATGACCAAATGTATTCTTTCAAAA
  ATAAAAAAGGGGAGAGGGAAGCTGCATGTTTTTAAAAATTGAAATTATTTAGGGATAAAA
  CACTAACTCTAGTGCCTTTAACGGGCAATAGCAACTTTTTTCCTCCGAAGTCAAACACCA
  TCCCCAGCTGAGCCTTTGTGCTACAAGCTTTTCAGGAGATGTTACCTAAACTTTATTAAA
  AGAAAAGAACAAGTTTAAATATAGACACTGGACTAGCCCAGTCTGTATTTTCAAGTCCAC
  ATTCTTCATCTGAAGCACTGCATCAGGGACCCCCCTGAGTCTGCAAGTTTTCAAGTTCAC
  AGTACATGGAACCAGTTTTTCTTTTTAATTTTTTCCTCACTCAGAGCAGCCACACACAGT
  GGCCGTTGACGCTGGAACCTCGGGCGGGGCCTTTTCCTACATGGCCTGCNCGGAGCTGCC
  CAAGGTTNCTCCTCAATGAGAATCGATGCTGTCATGCTCTATGGATGGGNNAAAAGCAGA
  TATAAAGCACCTGTACAGGTTCATCANACCATTCGGGATCGCTATGTTCAAACCGCTGCT
  GAACGCATTTGNCACTTTTGTGTGTTGAACAGTTGTGGCCTGAAGTAGNCTCATANAAGA
  ACGTAATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006852
• ORF Size: 2253 bp
• Insert Size: 3270
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006852.2, NP_006843.2
• RefSeq Size: 3616
• RefSeq ORF: 2253
• Locus ID: 11011
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (A) lacks an alternate in-frame exon in the 3' coding region compared to variant C. The encoded protein (isoform A) is shorter than isoform C.