TLK2 (NM_006852) Human Untagged Clone

CAT#: SC115810

TLK2 (untagged)-Human tousled-like kinase 2 (TLK2), transcript variant A


  "NM_006852" in other vectors (8)

Reconstitution Protocol

SC115810 is the updated version of SC115812.

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TLK2
Synonyms HsHPK; MRD57; PKU-ALPHA
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_006852 edited
ATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTT
ACTGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGC
AGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAG
CGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGG
GGACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGCGCCAGGAACCAGCCCT
GGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTA
CCGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACG
GAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGAC
ACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAA
AACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAG
ATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTA
GAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGA
GCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAG
GAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAA
GAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACT
ACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAAT
CTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAA
ATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAG
AAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATAC
CATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAG
ATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAA
AGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATAT
TTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTA
ACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAG
AAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGAT
CATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACA
GTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATG
TCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAAT
GAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAAT
GGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGAT
GATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGG
TATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTT
GATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGC
CATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTG
CAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTG
GCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTG
CCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACC
TCTGGGGCGTCCAATAACAGTTCTTCTAATTGA
>OriGene 5' read for NM_006852 unedited
CACATTTTGTATACGACTCATATAGGCGGCCGCGAATTCGGCACGAGGCGGCAGCAGAAT
GATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTAC
TGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAG
CGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCG
AAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGG
ACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGCGCCAGGAACCAGCCCTGG
CAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACC
GCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGA
GGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACAC
AGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAA
CAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGAT
CTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGA
AAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATNTATTAAGAGC
CAACTGTGATTTGAGACGGCAGATTGATGAACAGCANAAGATGCTAGAGAAATACAGGNA
ACGNATAAATAGATGTGTGACAAATGAGCAGAAACTCCTTATAGAAAAGTCAAAACAAGA
GAAAGAGGNCGTGTAGAGAATAGAAGCATGCAAACCGCTTGAGACTGGGCCACTTTACTA
CTGTCCGACACG
>OriGene 3' read for NM_006852 unedited
CGCGGCCGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGCATGGACAGATGAACCTT
TATTTAAAAAAAAGCACTTCAAATAAATTAAAAGGGACAACCGTCAAGTGTTCAAATTGT
GAAGAAATAGTTGAAAACCTAGAGAGACTCCAAGCTGCAGTCTTCTAACCTCATTCTTTG
TCCAATGGCAAAAACCCACACATCTCAGTACTCCCACTCAATTTTTTCCCTACTGAGATG
AGGGAAGCAATTGCAAACAGGAGACCAGACGGAGGAGAAAGCTGCATCTGATTGGAATGA
ACATTGCCACGTACTTGCTAATACGGGTTTCACTTTATGACCAAATGTATTCTTTCAAAA
ATAAAAAAGGGGAGAGGGAAGCTGCATGTTTTTAAAAATTGAAATTATTTAGGGATAAAA
CACTAACTCTAGTGCCTTTAACGGGCAATAGCAACTTTTTTCCTCCGAAGTCAAACACCA
TCCCCAGCTGAGCCTTTGTGCTACAAGCTTTTCAGGAGATGTTACCTAAACTTTATTAAA
AGAAAAGAACAAGTTTAAATATAGACACTGGACTAGCCCAGTCTGTATTTTCAAGTCCAC
ATTCTTCATCTGAAGCACTGCATCAGGGACCCCCCTGAGTCTGCAAGTTTTCAAGTTCAC
AGTACATGGAACCAGTTTTTCTTTTTAATTTTTTCCTCACTCAGAGCAGCCACACACAGT
GGCCGTTGACGCTGGAACCTCGGGCGGGGCCTTTTCCTACATGGCCTGCNCGGAGCTGCC
CAAGGTTNCTCCTCAATGAGAATCGATGCTGTCATGCTCTATGGATGGGNNAAAAGCAGA
TATAAAGCACCTGTACAGGTTCATCANACCATTCGGGATCGCTATGTTCAAACCGCTGCT
GAACGCATTTGNCACTTTTGTGTGTTGAACAGTTGTGGCCTGAAGTAGNCTCATANAAGA
ACGTAATG
Restriction Sites NotI-NotI     
ACCN NM_006852
ORF Size 2253 bp
Insert Size 3270
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_006852.2, NP_006843.2
RefSeq Size 3616
RefSeq ORF 2253
Locus ID 11011
Domains pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
Gene Summary This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Transcript Variant: This variant (A) lacks an alternate in-frame exon in the 3' coding region compared to variant C. The encoded protein (isoform A) is shorter than isoform C.

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