Myotilin (MYOT) (NM_006790) Human Untagged Clone

CAT#: SC115849

MYOT (untagged)-Human myotilin (MYOT), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYOT
• Synonyms: LGMD1; LGMD1A; MFM3; TTID; TTOD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115849 sequence for NM_006790 edited (data generated by NextGen Sequencing)
  ATGTTTAACTACGAACGTCCAAAACACTTCATCCAGTCCCAAAACCCATGTGGCTCCAGA
  TTGCAGCCTCCTGGACCAGAAACCTCCAGCTTCTCTAGCCAGACCAAACAGTCTTCCATT
  ATCATCCAGCCCCGCCAGTGTACAGAGCAAAGATTTTCTGCCTCCTCAACACTGAGCTCT
  CACATCACCATGTCCTCCTCTGCTTTCCCTGCTTCTCCCCAGCAGCATGCTGGCTCCAAC
  CCAGGCCAAAGGGTTACAACCACCTATAACCAGTCCCCAGCCAGCTTCCTCAGCTCCATA
  TTACCATCACAGCCTGATTACAATAGCAGTAAAATCCCTTCCGCTATGGATTCCAACTAT
  CAACAGTCCTCAGCTGGCCAACCTATAAATGCAAAGCCATCCCAAACTGCAAATGCTAAG
  CCCATACCAAGAACTCCTGATCATGAAATACAAGGATCAAAAGAAGCTTTGATTCAAGAT
  TTGGAAAGAAAGCTGAAATGCAAGGACACCCTTCTTCATAATGGAAATCAACGTCTAACA
  TATGAAGAGAAGATGGCTCGCAGATTGCTAGGACCACAGAATGCAGCTGCTGTGTTTCAA
  GCTCAGGATGACAGTGGTGCACAAGACTCGCAGCAACACAACTCAGAACATGCGCGACTG
  CAAGTTCCTACATCACAAGTAAGAAGTAGATCAACCTCAAGGGGAGATGTGAATGATCAG
  GATGCAATCCAGGAGAAATTTTACCCACCACGTTTCATTCAAGTGCCAGAGAACATGTCG
  ATTGATGAAGGAAGATTCTGCAGAATGGACTTCAAAGTGAGTGGACTGCCAGCTCCTGAT
  GTGTCATGGTATCTAAATGGAAGAACAGTTCAATCAGATGATTTGCACAAAATGATAGTG
  TCTGAGAAGGGTCTTCATTCACTCATCTTTGAAGTAGTCAGAGCTTCAGATGCAGGGGCT
  TATGCATGTGTTGCCAAGAATAGAGCAGGAGAAGCCACCTTCACTGTGCAGCTGGATGTC
  CTTGCAAAAGAACATAAAAGAGCACCAATGTTTATCTACAAACCACAGAGCAAAAAAGTT
  TTAGAGGGAGATTCAGTGAAACTAGAATGCCAGATCTCGGCTATACCTCCACCAAAGCTT
  TTCTGGAAAAGAAATAATGAAATGGTACAATTCAACACTGACCGAATAAGCTTATATCAA
  GATAACACTGGAAGAGTTACTTTACTGATAAAAGATGTAAACAAGAAAGATGCTGGGTGG
  TATACTGTGTCAGCAGTTAATGAAGCTGGAGTGACTACATGTAACACAAGATTAGACGTT
  ACGGCACGTCCAAACCAAACTCTTCCAGCTCCTAAGCAGTTACGGGTTCGACCAACATTC
  AGCAAATATTTAGCACTTAATGGGAAAGGTTTGAATGTAAAACAAGCTTTTAACCCAGAA
  GGAGAATTTCAGCGTTTGGCAGCTCAATCTGGACTCTATGAAAGTGAAGAACTTTAA
  
  Clone variation with respect to NM_006790.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006790 unedited
  TATAGGGCGGCCGCGAATTCGGCACGAGGATGCCTCTTCCTTCCCTTCAATAGTGGGTTA
  AACCCAGCTGGCACCCTCTGGAACTACGGGAACAATATTCTTCAAGAGAAGGTCACTCTA
  CCAAAGCCAGGAGCACAGTATTCTCAGGATCTCAACAAGGAAGAGCAGACCAAGGTTGCT
  TCTGATTCCTTACAACCTTCCGTAATTCCAGGCTTGTGGCCCCAAATTCAGGGCCCCACC
  CTTCCAGGAACAAATCATTATAGTNAATAATTTGGCCTTCATCCTTCCATATACCAACTA
  AGCATGTTTAACTACGAACGTCCAAAACACTTCATCCAGTCCCAAAACCCATGTGGCTCC
  AGATTGCAGCCTCCTGGACCAGAAACCTCCAGCTTCTCTAGCCAGACCAAACAGTCTTCC
  ATTATCATCCAGCCCCGCCAGTGTACAGAGCAAAGATTTTCTGCCTCCTCAACACTGAGC
  TCTCACATCACCATGTCCTCCTCTGCTNTCCCTGCTTCTCCCCAGCAGCATGCTGGCTCC
  AACCCAGGCCAAAGGGTTACAACCACCTATAACCAGTCCCCAGCCAGCTTCCTCAGCTCC
  ATATTACCATCACAGCCTGATTACANTAGCAGTAAAATCCCTTCCGCTATGGATTCCAAC
  TATCAACAGTCCTCAGCTGGCCAACCTANTAATGCANAGCCATCCCAAACTGCANATGCT
  AAAGCCATACCNAGAACTNCTGATCATGAAATACANGGATCANAAGAAGCTNTGATTNCA
  GATTTGGAAAGAAAGCTGNAATGCANGGACACCCTTNCTTCATATGGANNATCACGTCTA
  CATATGAAGAGAAGATGGCTCGCANATTGCTAGGACACAGAATGCAGCTGCTGTGTTTCA
  AGCTCAGATGACAGTGTGCACAGACTCGCAGCACACACTCAGACATGCGCGACTGCAGTN
  CTACATACAAGTAGAGTANATCACTAGGGGGATGGGATGATCAGAGCATCAGAGAATTTA
  CCACCGTTCATCAGGCCAAAACTGTGTGTGAAGAGACTGCAAGGACTCAGGAGGCTGCCC
  CTGAGGATGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006790 unedited
  ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTAAATATTTG
  AATTTTATTTTCTTTTGACATACAACTGTGGAACACTCAGATAATCTATACCATGTTAGT
  ATTCCTACAAGAGAAAACGGGTAAAACAGTATTTAGAAAGCAGTACCAGTAAACGTTATT
  ACAAGCATTAGATGTGTTTAAAAAGTTGATACTAATTTATAACCTGTAATTGTTAAATGT
  GCATGACTTAAATGTTAAAATCCTGTATTTTAAGATAGTCTTCTGCAGTTACAAATCCAT
  ATACCCAGATTTCCTGTAGGCTTCACAAATCGGAGGGGTACATAGAATGTGCAAGAGTCA
  AAGGATAAATAATATTATAAATATATATTAACTATATTACCTAATTAAAACCATAATCTG
  TTAATACAGCTATGGATTAATTTCAAAAAAATGTAATCAAATATATTACTAATGGTGTAG
  TTGGCTGTTTTCCAATGTTGGTAAAGTTATTAAAGTTCTTCACTTTCATAGAGTCCAGAT
  TGAGCTGCCAAACGCTGAAATTCTCCTTCTGGGTTAAAAGCTTGTTTTACATTCAAACCT
  TTCCCATTAAGTGCTAAATATTTGCTGAATGTTGGTCGAACCCGTAACTGCTTAGGAGCT
  GGAAGAGTTTGGTTTGGACGTGCCGTAACGTCTAATCTTGTGGTACATGTAGTCACTCCA
  GCTTCATTAACTGCTGACACAGTATACCACCCAGCATCTTTCTTGGTTACATCTTTTATC
  AGTAAAGTACTCTTNCAGTGTTATCTTGATATAAGCTTATTCGGNCAGTGTTGAATTGTA
  CCATTTCATTATTNCTTTTCAGNAAGCTTTGGTGGANGTATAGNCGAGATCTGGCATTCT
  AGTTCACTGAATCTCCCTCTAAACTTTTTGCTCGNGGNTNNGAGAAAACATGGGCTCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006790
• ORF Size: 1497 bp
• Insert Size: 2240
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006790.1, NP_006781.1
• RefSeq Size: 2244
• RefSeq ORF: 1497
• Locus ID: 9499
• Domains: ig, IGc2, IG
• Gene Summary: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).