Myotilin (MYOT) (NM_006790) Human Untagged Clone

CAT#: SC320817

MYOT (untagged)-Human myotilin (MYOT), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYOT
• Synonyms: LGMD1; LGMD1A; MFM3; TTID; TTOD
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006790.1 AGTCTGTGAGGGAAGGAGATGCCTCTTCCTTCCCTTCAATAGTGGGTTAAACCCAGCTGG
  CACCCTCTGGAACTACGGGAACAATATTCTTCAAGAGAAGGTCACTCTACCAAAGCCAGG
  AGCACAGTATTCTCAGGATCTCAACAAGGAAGAGCAGACCAAGGTTGCTTCTGATTCCTT
  ACAACCTTCCGTAATTCCAGGCTTGTGGCCCCAAATTCAGGGCCCCACCCTTCCAGGAAC
  AAATCATTATAGTAATAATTTGCCTTCATCTTCCATATACCAACTAAGCATGTTTAACTA
  CGAACGTCCAAAACACTTCATCCAGTCCCAAAACCCATGTGGCTCCAGATTGCAGCCTCC
  TGGACCAGAAACCTCCAGCTTCTCTAGCCAGACCAAACAGTCTTCCATTATCATCCAGCC
  CCGCCAGTGTACAGAGCAAAGATTTTCTGCCTCCTCAACACTGAGCTCTCACATCACCAT
  GTCCTCCTCTGCTTTCCCTGCTTCTCCCCAGCAGCATGCTGGCTCCAACCCAGGCCAAAG
  GGTTACAACCACCTATAACCAGTCCCCAGCCAGCTTCCTCAGCTCCATATTACCATCACA
  GCCTGATTACAATAGCAGTAAAATCCCTTCCGCTATGGATTCCAACTATCAACAGTCCTC
  AGCTGGCCAACCTATAAATGCAAAGCCATCCCAAACTGCAAATGCTAAGCCCATACCAAG
  AACTCCTGATCATGAAATACAAGGATCAAAAGAAGCTTTGATTCAAGATTTGGAAAGAAA
  GCTGAAATGCAAGGACACCCTTCTTCATAATGGAAATCAACGTCTAACATATGAAGAGAA
  GATGGCTCGCAGATTGCTAGGACCACAGAATGCAGCTGCTGTGTTTCAAGCTCAGGATGA
  CAGTGGTGCACAAGACTCGCAGCAACACAACTCAGAACATGCGCGACTGCAAGTTCCTAC
  ATCACAAGTAAGAAGTAGATCAACCTCAAGGGGAGATGTGAATGATCAGGATGCAATCCA
  GGAGAAATTTTACCCACCACGTTTCATTCAAGTGCCAGAGAACATGTCGATTGATGAAGG
  AAGATTCTGCAGAATGGACTTCAAAGTGAGTGGACTGCCAGCTCCTGATGTGTCATGGTA
  TCTAAATGGAAGAACAGTTCAATCAGATGATTTGCACAAAATGATAGTGTCTGAGAAGGG
  TCTTCATTCACTCATCTTTGAAGTAGTCAGAGCTTCAGATGCAGGGGCTTATGCATGTGT
  TGCCAAGAATAGAGCAGGAGAAGCCACCTTCACTGTGCAGCTGGATGTCCTTGCAAAAGA
  ACATAAAAGAGCACCAATGTTTATCTACAAACCACAGAGCAAAAAAGTTTTAGAGGGAGA
  TTCAGTGAAACTAGAATGCCAGATCTCGGCTATACCTCCACCAAAGCTTTTCTGGAAAAG
  AAATAATGAAATGGTACAATTCAACACTGACCGAATAAGCTTATATCAAGATAACACTGG
  AAGAGTTACTTTACTGATAAAAGATGTAAACAAGAAAGATGCTGGGTGGTATACTGTGTC
  AGCAGTTAATGAAGCTGGAGTGACTACATGTAACACAAGATTAGACGTTACGGCACGTCC
  AAACCAAACTCTTCCAGCTCCTAAGCAGTTACGGGTTCGACCAACATTCAGCAAATATTT
  AGCACTTAATGGGAAAGGTTTGAATGTAAAACAAGCTTTTAACCCAGAAGGAGAATTTCA
  GCGTTTGGCAGCTCAATCTGGACTCTATGAAAGTGAAGAACTTTAATAACTTTACCAACA
  TTGGAAAACAGCCAACTACACCATTAGTAATATATTTGATTACATTTTTTTGAAATTAAT
  CCATAGCTGTATTAACAGATTATGGTTTTAATTAGGTAATATAGTTAATATATATTTATA
  ATATTATTTATCCTTTGACTCTTGCACATTCTATGTACCCCTCCGATTTGTGAAGCCTAC
  AGGAAATCTGGGTATATGGATTTGTAACTGCAGAAGACTATCTTAAAATACAGGATTTTA
  ACATTTAAGTCATGCACATTTAACAATTACAGGTTATAAATTAGTATCAACTTTTTAAAC
  ACATCTAATGCTTGTAATAACGTTTACTGGTACTGCTTTCTAAATACTGTTTTACCCGTT
  TTCTCTTGTAGGAATACTAACATGGTATAGATTATCTGAGTGTTCCACAGTTGTATGTCA
  AAAGAAAATAAAATTCAAATATTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006790.1 unedited
  TACACTTGTATACGACTCCTATAGGGCGGCTCGGCAATTCGGCCACCTACGGCCGGGGAG
  TCTGTGAGGGAAGGAGATGCCTCTTCCTTCCCTTCAATAGTGGGTTAAACCCAGCTGGCA
  CCCTCTGGAACTACGGGAACAATATTCTTCAAGAGAAGGTCACTCTACCAAAGCCAGGAG
  CACAGTATTCTCAGGATCTCAACAAGGAAGAGCAGACCAAGGTTGCTTCTGATTCCTTAC
  AACCTTCCGTAATTCCAGGCTTGTGGCCCCAAATTCAGGGCCCCACCCTTCCAGGAACAA
  ATCATTATAGTAATAATTTGCCTTCATCTTCCATATACCAACTAAGCATGTTTAACTACG
  AACGTCCAAAACACTTCATCCAGTCCCAAAACCCATGTGGCTCCAGATTGCAGCCTCCTG
  GACCAGAAACCTCCAGCTTCTCTAGCCAGACCAAACAGTCTTCCATTATCATCCAGCCCC
  GCCAGTGTACAGAGCAAAGATTTTCTGCCTCCTCAACACTGAGCTCTCACATCACCATGT
  CCTCCTCTGCTTTCCCTGCTTCTCCCCAGCAGCATGCTGGCTCCAACCCAGGCCAAAGGG
  TTACAACCACCTATAACCAGTCCCCAGCCAGCTTCCTCAGCTCCATATTACCATCACAGC
  CTGATTACAATAGCAGTAAAATCCCTTCCGCTATGGATTCCAACTATCAACAGTCCTCAG
  CTGGCCAACCTATAAATGCAAAGCCATCCCAAACTGCAAATGCTAAGCCCATACCAAGAA
  CTCCTGATCATGAAATACACGATCAAAAGAAGCTTTGATTCAAGATTTGAAAGAAAGCTG
  AAATGCAAGACACCCTTCTTCATATGGAATCACGTCTACATATGAAGAGAAAATGCTCGC
  AAATGCTAGACCACAGAATGCAGCTGCTGTGGTTTCAAGCCTCAAGGATGAACGTT
• Restriction Sites: Please inquire
• ACCN: NM_006790
• ORF Size: 1497 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006790.1, NP_006781.1
• RefSeq Size: 2244
• RefSeq ORF: 1497
• Locus ID: 9499
• Domains: ig, IGc2, IG
• Gene Summary: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).