NTE (PNPLA6) (NM_006702) Human Untagged Clone

CAT#: SC115919

PNPLA6 (untagged)-Human patatin-like phospholipase domain containing 6 (PNPLA6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNPLA6
• Synonyms: BNHS; iPLA2delta; LNMS; NTE; NTEMND; OMCS; SPG39; sws
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006702, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGCTCCGCTGCAAACTGGAATGGTGCTTGGCGTGATGATCGGGGCCGGAGTGGCGGTGGTGGTCA
  CGGCCGTGCTCATCCTCCTGGTGGTGCGGAGGCTGCGAGTGCCAAAAACCCCAGCCCCGGATGGCCCCCG
  GTATCGGTTCCGGAAGAGGGACAAAGTGCTCTTCTATGGCCGGAAGATTATGCGGAAGGTGTCACAATCC
  ACCTCCTCCCTCGTGGATACCTCTGTCTCCGCCACCTCCCGGCCACGCATGAGGAAGAAACTGAAGATGC
  TCAACATTGCCAAGAAGATCCTGCGCATCCAGAAAGAGACGCCCACGCTGCAGCGGAAGGAGCCCCCGCC
  CGCAGTGCTAGAAGCTGACCTGACCGAGGGCGACCTGGCTAACTCCCATCTGCCCTCTGAAGTGCTTTAT
  ATGCTCAAGAACGTCCGGGTGCTGGGCCACTTCGAGAAGCCACTCTTCCTGGAGCTCTGCCGCCACATGG
  TCTTCCAGCGGCTGGGCCAGGGTGACTACGTCTTCCGGCCGGGCCAGCCAGATGCCAGCATCTACGTGGT
  GCAGGACGGGCTGCTGGAGCTCTGTCTGCCAGGGCCTGACGGGAAGGAGTGTGTGGTGAAGGAAGTGGTT
  CCTGGGGACAGCGTCAACAGCCTTCTCAGCATCCTGGATGTCATCACCGGTCACCAGCATCCCCAGCGGA
  CCGTGTCTGCCCGGGCGGCCCGGGACTCCACGGTGCTGCGCCTGCCGGTGGAAGCATTCTCCGCGGTCTT
  CACCAAGTACCCGGAGAGCTTGGTGCGGGTCGTGCAGATCATCATGGTGCGGCTGCAGCGAGTCACCTTC
  CTGGCACTGCACAACTACCTGGGTCTGACCAATGAGCTCTTCAGCCACGAGATCCAGCCCCTGCGTCTGT
  TCCCCAGCCCCGGCCTCCCAACTCGCACCAGCCCTGTGCGGGGCTCCAAGAGAATGGTCAGCACCTCAGC
  TACAGACGAGCCCAGGGAGACCCCAGGGCGGCCACCCGATCCCACCGGGGCCCCGCTGCCTGGACCTACA
  GGGGACCCTGTGAAGCCCACATCCCTGGAAACCCCCTCGGCCCCTCTGCTGAGCCGCTGCGTCTCCATGC
  CAGGGGACATCTCAGGCTTGCAGGGTGGCCCCCGCTCCGACTTCGACATGGCCTATGAGCGTGGCCGGAT
  CTCCGTGTCCCTGCAGGAAGAGGCCTCCGGGGGGTCCCTGGCAGCCCCCGCTCGGACCCCCACTCAGGAG
  CCTCGTGAGCAGCCGGCAGGCGCCTGTGAATACAGCTACTGTGAGGATGAGTCGGCCACTGGTGGCTGCC
  CTTTCGGGCCCTACCAGGGCCGCCAGACCAGCAGCATCTTCGAGGCAGCAAAGCAGGAGCTGGCCAAGCT
  GATGCGGATTGAGGACCCCTCCCTCCTGAACAGCAGAGTCTTGCTGCACCACGCCAAAGCTGGCACCATC
  ATTGCCCGCCAGGGAGACCAGGACGTGAGCCTGCACTTCGTGCTCTGGGGCTGCCTGCACGTGTACCAGC
  GCATGATCGACAAGGCGGAGGACGTGTGCCTGTTCGTAGCGCAGCCCGGGGAACTGGTGGGGCAGCTGGC
  GGTGCTCACTGGCGAACCTCTCATCTTCACACTGCGAGCCCAACGCGACTGCACCTTCCTGCGGATCTCC
  AAGTCCGACTTCTATGAGATCATGCGCGCACAGCCCAGTGTGGTGCTGAGTGCGGCGCACACGGTGGCAG
  CCAGGATGTCGCCCTTCGTGCGCCAGATGGACTTCGCCATCGACTGGACTGCAGTGGAGGCGGGACGCGC
  GCTGTACAGGCAGGGCGACCGCTCCGACTGCACTTACATCGTGCTCAATGGGCGGCTGCGTAGCGTGATC
  CAGCGAGGCAGTGGCAAGAAGGAGCTGGTGGGCGAGTACGGCCGCGGCGACCTCATCGGCGTGGTGGAGG
  CACTGACCCGGCAGCCGCGAGCCACGACGGTGCACGCGGTGCGCGACACGGAGCTGGCCAAGCTTCCCGA
  GGGCACCTTGGGTCACATCAAACGCCGGTACCCGCAGGTCGTGACCCGCCTTATCCACCTACTGAGCCAG
  AAAATTCTAGGGAATTTGCAGCAGCTGCAAGGACCCTTCCCAGCAGGCTCTGGGTTGGGTGTGCCCCCAC
  ACTCGGAACTCACCAACCCAGCCAGCAACCTGGCAACTGTGGCAATCCTGCCTGTGTGTGCTGAGGTCCC
  CATGGTGGCCTTCACGCTGGAGCTGCAGCACGCCCTGCAGGCCATCGGTCCGACGCTACTCCTTAACAGT
  GACATCATCCGGGCACGCCTGGGGGCCTCCGCACTGGATAGCATCCAAGAGTTCCGGCTGTCAGGGTGGC
  TGGCCCAGCAGGAGGATGCACACCGTATCGTACTCTACCAGACGGACGCCTCGCTGACGCCCTGGACCGT
  GCGCTGCCTGCGACAGGCCGACTGCATCCTCATTGTGGGCCTGGGGGACCAGGAGCCTACCCTCGGCCAG
  CTGGAGCAGATGCTGGAGAACACGGCTGTGCGCGCCCTTAAGCAGCTAGTCCTGCTCCACCGAGAGGAGG
  GCGCGGGCCCCACGCGCACCGTGGAGTGGCTAAATATGCGCAGCTGGTGCTCGGGGCACCTGCACCTGCG
  CTGTCCGCGCCGCCTCTTTTCGCGCCGCAGCCCTGCCAAGCTGCATGAGCTCTACGAGAAGGTTTTCTCC
  AGGCGCGCGGACCGGCACAGCGACTTCTCCCGCTTGGCGAGGGTGCTCACGGGGAACACCATTGCCCTTG
  TGCTAGGCGGGGGCGGGGCCAGGGGCTGCTCGCACATCGGAGTACTAAAGGCATTAGAGGAGGCGGGGGT
  CCCCGTGGACCTGGTGGGCGGCACGTCCATTGGCTCTTTCATCGGAGCGTTGTACGCGGAGGAGCGCAGC
  GCCAGCCGCACGAAGCAGCGGGCCCGGGAGTGGGCCAAGAGCATGACTTCGGTGCTGGAACCTGTGTTGG
  ACCTCACGTACCCAGTCACCTCCATGTTCACTGGGTCTGCCTTTAACCGCAGCATCCATCGGGTCTTCCA
  GGATAAGCAGATTGAGGACCTGTGGCTGCCTTACTTCAACGTGACCACAGATATCACCGCCTCAGCCATG
  CGAGTCCACAAAGATGGCTCCCTGTGGCGGTACGTGCGCGCCAGCATGACGCTGTCGGGCTACCTGCCCC
  CGCTGTGCGACCCCAAGGACGGGCACCTACTCATGGATGGCGGCTACATCAACAATCTGCCAGCGGACAT
  CGCCCGCAGCATGGGTGCCAAAACGGTCATCGCCATTGACGTGGGGAGCCAGGATGAGACGGACCTCAGC
  ACCTACGGGGACAGCCTGTCCGGCTGGTGGCTGCTGTGGAAGCGGCTGAATCCCTGGGCTGACAAGGTAA
  AGGTTCCAGACATGGCTGAAATCCAGTCCCGCCTGGCCTACGTGTCCTGTGTGCGGCAGCTAGAGGTTGT
  CAAGTCCAGCTCCTACTGCGAGTACCTGCGCCCGCCCATCGACTGCTTCAAGACCATGGACTTTGGGAAG
  TTCGACCAGATCTATGATGTGGGCTACCAGTACGGGAAGGCGGTGTTTGGAGGCTGGAGCCGTGGCAACG
  TCATTGAGAAAATGCTCACAGACCGGCGGTCTACAGACCTTAATGAGAGCCGCCGTGCAGACGTGCTTGC
  CTTCCCAAGCTCTGGCTTCACTGACTTGGCAGAGATTGTGTCCCGGATTGAGCCCCCCACGAGCTATGTC
  TCTGATGGCTGTGCTGACGGAGAGGAGTCAGATTGTCTGACAGAGTATGAGGAGGACGCCGGACCCGACT
  GCTCGAGGGATGAAGGGGGGTCCCCCGAGGGCGCAAGCCCCAGCACTGCCTCCGAGATGGAGGAGGAGAA
  GTCGATTCTCCGGCAACGACGCTGTCTGCCCCAGGAGCCGCCCGGCTCAGCCACAGATGCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006702 unedited
  TATATTCCCGCCCGTTGNCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGAATCAACCGATGGAGGCTCCGCTGCAAACTGGAATGGTGCTTGGC
  GTGATGATCGGGGCCGGAGTGGCGGTGGTGGTCACGGCCGTGCTCATCCTCCTGGTGGTG
  CGGAGGCTGCGAGTGCCAAAAACCCCAGCCCCGGATGGCCCCCGGTATCGGTTCCGGAAG
  AGGGACAAAGTGCTCTTCTATGGCCGGAAGATTATGCGGAAGGTGTCACAATCCACCTCC
  TCCCTCGTGGATACCTCTGTCTCCGCCACCTCCCGGCCACGCATGAGGAAGAAACTGAAG
  ATGCTCAACATTGCCAAGAAGATCCTGCGCATCCAGAAAGAGACGCCCACGCTGCAGCGG
  AAGGAGCCCCCGCCCGCAGTGCTAGAAGCTGACCTGACCGAGGGCGACCTGGCTAACTCC
  CATCTGCCCTCTGAAGTGCTTTATATGCTCAAGAACGTCCGGGTGCTGGGCCACTTCGAG
  AAGCCACTCTTCCTGGAGCTCTGCCGCCACATGGTCTTCCAGCGGCTGGGCCAGGGTGAC
  TACGTCTTCCGGCCGGGCCAGCCAGATGCCAGCATCTACGTGGTGCAGGACGGGCTGCTG
  GAGCTCTGTCTGCCAGGGCCTGACGGGAAGGAGTGTGTGGTGAAGGAAATGGGTCCTGGN
  GACAGCGTCAACAGCCTTCTCAGCATNCTGGATGTCATCACCGGTCACCAGCATCCCCAC
  NGACCGTGTCTGCCCGGNCGGCCCGGACTNNCACGTGCTGCGCCTGCCGNTGAAGCATCT
  TNCGCGGTCTTCACCAGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006702 unedited
  CAGGCCATTGGNGATGGCAACTTCCAGGNCCAGGNANGAGCACTGGGGNAGGGGTCACAG
  GGNATGCCACCCGGGATCTGTTCAGGAAAAGCTATGACCGCGGCCGCAATCTAGAGTCGA
  GTTTTTTTTTTTTTTTTTTCCAAGAGGCGAGTTTATTGGGGGAGGGGCTGGTCCAAGTCA
  TCAGTGCAACACTGCATCCCCGCTCAGGGCAGGTCAGTCCAGTGTGTGGGCCGCGGGGGT
  CACAGGCATAGCAGCAGGAGGGGGAGTGAGCTTACCCCCACGGGGCCACCCCCAGCCCAG
  TCCAGGGGTGGGAGGGAGGGGGTGACCCCTGTCNAGGTCCTCANGCNTCTGNGGCTGNGC
  CGGGCGGCTCCTGGGGCNGACNGCGTCGTTGCCGGGGATTCGNCTTCTCCTCCTCNCTCT
  CGGGGGCCGTGCTGGGGCTTGCGCCCTCGGGGGCCCCCCCTTCCTCCCTCGGGCNGTCGG
  TTCCGGCGTCCTCGTCCTCCTCTGTGGTCCGTGCTGGTGTCCTCTCCGTCCGCGCGCCCT
  GTTGGCCTTCCTTGTCGGGGGCTGCCTTCCGTGTCCCTGCTCTGCCTGGTTCCGGGCGCC
  CGGGCTTGCGGCCGGCTGGGCGGCCGCGCCGGCGGGGCGGCTTCGGGTCCGCCCCTCCGC
  CGGCGGGCCCCCCGTCTTCCTTGTTGCCGNTNCGGCTTTCGCGCTCCCTGCTCCCTCTTT
  TTTTGGTGTGCGCCCGGCCTTNTTCCCCTTGCCCGTTCCCCCGCTTTCGCCTTTGTGTCG
  CCCCGGGTTTCCGCGCCCGCTCCTGCCCCCCCCCGTTCCCCCCGTCCCTTGTCCTTTTCG
  GGGCCCGGTCGCTGTGCCCTTGTTGGGCGGGCGGGTTTTTCGGTCCGCGCCTCTCGCCGC
  GCTGCCGTTGTTGTA
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_006702
• ORF Size: 3984 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006702.2, NP_006693.2
• RefSeq Size: 4490
• RefSeq ORF: 3984
• Locus ID: 10908
• Domains: cNMP, Patatin
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (b) lacks an internal segment near the N-terminus, compared to isoform a. Both variants 2 and 3 encode the same isoform.