Hsp105 (HSPH1) (NM_006644) Human Untagged Clone

CAT#: SC115932

HSPH1 (untagged)-Human heat shock 105kDa/110kDa protein 1 (HSPH1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HSPH1
• Synonyms: HSP105; HSP105A; HSP105B; NY-CO-25
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115932 sequence for NM_006644 edited (data generated by NextGen Sequencing)
  ATGTCGGTGGTGGGGTTGGACGTGGGCTCGCAGAGCTGCTACATCGCGGTAGCCCGGGCC
  GGGGGCATCGAGACCATCGCCAATGAGTTCAGCGACCGGTGCACCCCGTCAGTCATATCA
  TTTGGATCAAAAAATAGAACAATCGGAGTTGCAGCCAAAAATCAGCAAATCACTCATGCA
  AACAATACGGTGTCTAACTTCAAAAGATTTCATGGCCGAGCATTCAACGACCCCTTCATT
  CAAAAGGAGAAGGAAAACTTGAGTTACGATTTGGTTCCATTGAAAAATGGTGGAGTTGGA
  ATAAAGGTAATGTACATGGGTGAAGAACATCTATTTAGTGTGGAGCAGATAACAGCCATG
  TTGTTGACTAAGCTGAAGGAAACTGCTGAAAACAGCCTCAAGAAACCAGTAACAGATTGT
  GTTATTTCAGTCCCCTCCTTCTTTACAGATGCTGAGAGGCGATCTGTGTTAGATGCTGCA
  CAGATTGTTGGCCTAAACTGTTTAAGACTTATGAATGACATGACAGCTGTTGCTTTGAAT
  TACGGAATTTATAAGCAGGATCTCCCAAGCCTGGATGAGAAACCTCGGATAGTGGTTTTT
  GTTGATATGGGACATTCAGCTTTTCAAGTGTCTGCTTGTGCTTTTAACAAGGGAAAATTG
  AAGGTACTGGGAACAGCTTTTGATCCTTTCTTAGGAGGAAAAAACTTCGATGAAAAGTTA
  GTGGAACATTTCTGTGCAGAATTTAAAACTAAGTACAAGTTGGATGCAAAATCCAAAATA
  CGAGCACTCCTACGTCTGTATCAGGAATGTGAAAAACTGAAAAAGCTAATGAGCTCTAAC
  AGCACAGACCTTCCACTGAATATCGAATGCTTTATGAATGATAAAGATGTTTCCGGAAAG
  ATGAACAGGTCACAATTTGAAGAACTCTGTGCTGAACTTCTGCAAAAGATAGAAGTACCC
  CTTTATTCACTGTTGGAACAAACTCATCTCAAAGTAGAAGATGTGAGTGCAGTTGAGATT
  GTTGGAGGCGCTACACGAATTCCAGCTGTGAAGGAAAGAATTGCCAAATTCTTTGGAAAA
  GATATTAGCACAACACTCAATGCAGATGAAGCAGTAGCCAGAGGATGTGCATTACAGTGT
  GCAATACTTTCCCCGGCATTTAAAGTTAGAGAATTTTCCGTCACAGATGCAGTTCCTTTT
  CCAATATCTCTGATCTGGAACCATGATTCAGAAGATACTGAAGGTGTTCATGAAGTCTTT
  AGTCGAAACCATGCTGCTCCTTTCTCCAAAGTTCTCACCTTTCTGAGAAGGGGGCCTTTT
  GAGCTAGAAGCTTTCTATTCTGATCCCCAAGGAGTTCCATATCCAGAAGCAAAAATAGGC
  CGCTTTGTAGTTCAGAATGTTTCTGCACAGAAAGATGGAGAAAAATCTAGAGTAAAAGTC
  AAAGTGCGAGTCAACACCCATGGCATTTTCACCATCTCTACGGCATCTATGGTGGAGAAA
  GTCCCAACTGAGGAGAATGAAATGTCTTCTGAAGCTGACATGGAGTGTCTGAATCAGAGA
  CCACCAGAAAACCCAGACACTGATAAAAATGTCCAGCAAGACAACAGTGAAGCTGGAACA
  CAGCCCCAGGTACAAACTGATGCTCAACAAACCTCACAGTCTCCCCCTTCACCTGAACTT
  ACCTCAGAAGAAAACAAAATCCCAGATGCTGACAAAGCAAATGAAAAAAAAGTTGACCAG
  CCTCCAGAAGCTAAAAAGCCCAAAATAAAGGTGGTGAATGTTGAGCTGCCTATTGAAGCC
  AACTTGGTCTGGCAGTTAGGGAAAGACCTTCTTAACATGTATATTGAGACAGAGGGTAAG
  ATGATAATGCAAGATAAATTGGAAAAAGAAAGGAATGATGCTAAAAATGCAGTTGAGGAA
  TATGTGTATGAGTTCAGAGACAAGCTGTGTGGACCATATGAAAAATTTATATGTGAGCAG
  GATCATCAAAATTTTTTGAGACTCCTCACAGAAACTGAAGACTGGCTGTATGAAGAAGGA
  GAGGACCAAGCTAAACAAGCATATGTTGACAAGTTGGAAGAATTAATGAAAATTGGCACT
  CCAGTTAAAGTTCGGTTTCAGGAAGCTGAAGAACGGCCAAAAATGTTTGAAGAACTAGGA
  CAGAGGCTGCAGCATTATGCCAAGATAGCAGCTGACTTCAGAAATAAGGATGAGAAATAC
  AACCATATTGATGAGTCTGAAATGAAAAAAGTGGAGAAGTCTGTTAATGAAGTGATGGAA
  TGGATGAATAATGTCATGAATGCTCAGGCTAAAAAGAGTCTTGATCAGGATCCAGTTGTA
  CGTGCTCAGGAAATTAAAACAAAAATCAAGGAATTGAACAACACATGTGAACCCGTTGTA
  ACACAACCGAAACCAAAAATTGAATCACCCAAACTGGAAAGAACTCCAAATGGCCCAAAT
  ATTGATAAAAAGGAAGAAGATTTAGAAGACAAAAACAATTTTGGTGCTGAACCTCCACAT
  CAGAATGGTGAATGTTACCCTAATGAGAAAAATTCTGTTAATATGGACTTGGACTAG
  
  Clone variation with respect to NM_006644.2
  228 t=>c;732 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006644 unedited
  ATACGACTACTATAGGGCGGCCGCGAATCGGCACGAGGGGCTGAGGAAGTGGGACCTCCC
  CTTTTGGGTCGGTAGTTCAGCGCCGGCGCCGGTGTGCGAGCCGCGGCAGAGTGAGGCAGG
  CAACCCGAGGTGCGGAGCGACCTGCGGAGGCTGAGCCCCGCTTTCTCCCAGGGTTTCTTA
  TCAGCCAGCCGCCGCTGTCCCCGGGGGAGTAGGAGGCTCCTGACAGGCCGCGGCTGTCTG
  TGTGTCCTTCTGAGTGTCAGAGGAACGGCCAGACCCCGCGGGCCGGAGCAGAACGCGGCC
  AGGGCAGAAAGCGGCGGCAGGAGAAGCAGGCAGGGGGCCGGAGGACGCAGACCGAGACCC
  GAGGCGGAGGCGGACCGCGAGCCGGCCATGTCGGTGGTGGGGTTGGACGTGGGCTCGCAG
  AGCTGCTACATCGCGGTAGCCCGGGCCGGGGGCATCGAGACCATCGCCAATGAGTTCAGC
  GACCGGTGCACCCCGTCAGTCATATCATTTGGATCAAAAAATAGAACAATCGGAGTTGCA
  GCCAAAAATCAGCAAATCACTCATGCAAACAATACGGTGTCTAACTTCAAAAGATTTCAT
  GGCCGAGCATTCAACGACCCCTTCATTCAAAAGGAGAAGGAAAACTTGAGTTACGATTTG
  GTTCCATTGAAAAATGGTGGAGTTGGAATAAGGTAATGTACATGGGTGAAGACATCTATN
  TAGTGTGGAGCAGATACAGCCATGTTGNTGACTAAGCTGAAGGAAACTGCTGAAAACAGC
  CTCAAGAACCAGTNNACAGATGTGTATTTCAGTCCCCTCCTTCTTTACGATGCTGAGAGG
  CGATCTGTGNTAGATGCTGCACAGATGGNTGCCCTAACTGTNTAGAACTATGAATGACAT
  GACAGCTGTGCTTTGATTACGGAATTATAANCAGACTCCCAGCCTGATGAGAACTCGGGA
  AGGGGGGTTTGTGGAATGGAAANTCACCTTNCAGGGTCTGCTGTGCTTACAGGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006644 unedited
  GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTGGAAAGAC
  ACCATAAGATGAACTTTATTTTAAAGCTCATAAAAGTGTTCACAATCAGTTACAACAGGA
  TCGACATTTCTTCCATTCCACACTTTCACATGACAATATACTGTATAGTGAGAGAGAAAG
  TTTAAAGTTTTTGTTCTGCATGCTGCTAACACATTTGACTAGCTTTTGTTTTACTCATTG
  AATTTTTAATATCAAAGCAAAAAGTCATTTTCTCTTGGACAGAAATGGTTTTAGAAAGCC
  CTTATGAAGTCAGACTTAGTCTTGTTTATAAACATCCACACCCACACACATGCTGAATGG
  AGAGCAAAATGCAAGAAAACTACCTTGGCAGGAACAAATGCTTAAAGATTTTAATCACAG
  CCCTCTTGAACAAGCAGTACAGTTTTTTTTCTCCAAAAGACAAAAGTCAGTTTCATCCTC
  AGTGATGCAAATGGTGAGACTGCACAGAAAGCTTAGTATGAATTCACAATTCCACAGGAA
  TCTGAAAGTTACCAAGGCAATTTTCCCTTTTAGGATCATAAAGACTACAGACTTAAGCTT
  TTTTTCTTTTTCCATATAATACACAAAATTTCTAAATATCCTTAAAAAAGAAAATATAAA
  TAGTTTCAGTATGTTATGTAGAGTCACATACTATGGCAAAAATATTTTATTAATTGAAGG
  AATAGGCCAATTTAAGGTTATCTAGTCCAAGTCCATATTAACAGAATTTTTCTCATTAGG
  GTAACATTCACCATTCTGTGGNGGGNAGGTTCAGCACCAAAAATGGNGTTTTGGNCTTCT
  AAATCTTCTTCCTTTTTATCAATNATTTGGCCAATTTTGGNAGTCTTTTCCAGTTTGGGT
  GAGTCAAATNTTGGGNTTTCGCGTTGGGGTACAACNGGGNTCACAAGGNGGTGNTCAATT
  CCCTTGAATTTTGGTTTAATTCCCTGAGCCGTACACCTGGAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006644
• ORF Size: 2577 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006644.2, NP_006635.2
• RefSeq Size: 3680
• RefSeq ORF: 2577
• Locus ID: 10808
• Domains: HSP70
• Protein Families: Stem cell - Pluripotency
• Gene Summary: This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1, also known as Hsp105alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.