NC2 alpha (DRAP1) (NM_006442) Human Untagged Clone

CAT#: SC116124

DRAP1 (untagged)-Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DRAP1
• Synonyms: NC2-alpha
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006442, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCGAGCAAGAAGAAGAAGTACAACGCGCGGTTCCCGCCGGCGCGGATCAAGAAGATCATGCAGACGG
  ACGAAGAGATTGGGAAGGTGGCGGCGGCGGTGCCTGTCATCATCTCCCGGGCGCTCGAGCTCTTCCTAGA
  GTCGCTGTTGAAGAAGGCCTGCCAGGTGACCCAGTCGCGGAACGCGAAGACCATGACCACATCCCACCTG
  AAGCAGTGCATCGAGCTGGAGCAGCAGTTTGACTTCTTGAAGGACCTGGTGGCATCTGTTCCCGACATGC
  AGGGGGACGGGGAAGACAACCACATGGATGGGGACAAGGGCGCCCGCAGGGGCCGGAAGCCAGGCAGCGG
  CGGCCGGAAGAACGGTGGGATGGGAACGAAAAGCAAGGACAAGAAGCTGTCCGGGACAGACTCGGAGCAG
  GAGGATGAATCTGAGGACACAGATACTGATGGGGAAGAGGAGACATCACAACCCCCACCCCAGGCCAGCC
  ACCCCTCTGCCCACTTTCAGAGCCCCCCGACACCCTTCCTGCCCTTCGCCTCTACTCTGCCTTTGCCCCC
  AGCGCCCCCGGGCCCCTCAGCACCTGATGAAGAGGACGAAGAAGATTACGACTCCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006442 unedited
  CACGAGGGGAGCCGGGAGGCTGCGGGCGGCGGCGCTGGACCCGACGCGGCGAGAGAGGCC
  CCGAGATGCCGAGCAAGAAGAAGAAGTACAACGCGCGGTTCCCGCCGGCGCGGATCAAGA
  AGATCATGCAGACGGACGAAGAGATTGGGAAGGTGGCGGCGGCGGTGCCTGTCATCATCT
  CCCGGGCGCTCGAGCTCTTCCTAGAGTCGCTGTTGAAGAAGGCCTGCCAGGTGACCCAGT
  CGCGGAACGCGAAGACCATGACCACATCCCACCTGAAGCAGTGCATCGAGCTGGAGCAGC
  AGTTTGACTTCTTGAAGGACCTGGTGGCATCTGTTCCCGACATGCAGGGGGACGGGGAAG
  ACAACCACATGGATGGGGACAAGGGCGCCCGCAGGGGCCGGAAGCCAGGCAGCGGCGGCC
  GGAAGAACGGTGGGATGGGAACGAAAAGCAAGGACAAGAAGCTGTCCGGGACAGACTCGG
  AGCAGGAGGATGAATCTGAGGACACAGATACTGATGGGGAAGAGGAACATNNACAAACCC
  CCACCCCAGGCCAGCCACCCCTCTGCCCACTTTCAGAGCCCCCCGACACCCTTCCTGCCC
  TTCGCCTCTACTCTGCCTTTGCCCCCAGCGCCCCCGGGCCCCTCAGCACCTGATGAAGAG
  GACGAAGAAGATTACGACTCCTAGCGCCTTCTGCCCCCCAGACCATAGCCCCTTTTAGTT
  GGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006442
• ORF Size: 618 bp
• Insert Size: 890
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006442.2, NP_006433.2
• RefSeq Size: 988
• RefSeq ORF: 618
• Locus ID: 10589
• Protein Families: Transcription Factors
• Gene Summary: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]