GCS1 (MOGS) (NM_006302) Human Untagged Clone

CAT#: SC116210

MOGS (untagged)-Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MOGS
• Synonyms: CDG2B; CWH41; DER7; GCS1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006302, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCGGGGCGAGCGGCGGCGCCGCGCAGTGCCGGCAGAGGGAGTGCGGACAGCCGAGAGGGCGGCTC
  GGGGAGGCCCCGGGCGACGGGACGGCCGGGGCGGCGGGCCGCGTAGCACGGCTGGAGGAGTGGCTCTGGC
  CGTCGTGGTCCTGTCTTTGGCCCTGGGTATGTCGGGGCGCTGGGTGCTGGCGTGGTACCGTGCGCGGCGG
  GCGGTCACGCTGCACTCCGCGCCTCCTGTGTTGCCTGCCGACTCCTCCAGCCCCGCCGTGGCCCCGGACC
  TCTTCTGGGGAACCTACCGCCCTCACGTCTACTTCGGCATGAAGACCCGCAGCCCGAAGCCCCTCCTCAC
  CGGACTGATGTGGGCGCAGCAGGGCACCACCCCGGGGACTCCTAAGCTCAGGCACACGTGTGAGCAGGGG
  GACGGTGTGGGTCCCTATGGCTGGGAGTTCCACGACGGCCTCTCCTTCGGGCGCCAACACATCCAGGATG
  GGGCCTTAAGGCTCACCACTGAGTTCGTCAAGAGGCCTGGGGGTCAGCACGGAGGGGACTGGAGCTGGAG
  AGTGACTGTAGAGCCTCAGGACTCAGGTACTTCTGCCCTCCCTTTGGTCTCCCTGTTCTTCTATGTGGTG
  ACAGATGGCAAGGAAGTCCTACTACCAGAGGTTGGGGCCAAGGGGCAGTTGAAGTTTATCAGTGGGCACA
  CCAGTGAACTTGGTGACTTCCGCTTTACACTTTTGCCACCAACCAGTCCAGGGGATACAGCCCCCAAGTA
  TGGCAGCTACAATGTCTTCTGGACCTCCAACCCAGGACTGCCCCTGCTGACAGAGATGGTAAAGAGTCGC
  CTAAATAGCTGGTTTCAGCATCGGCCCCCAGGGGCCCCCCCTGAACGCTACCTCGGCTTGCCAGGATCCC
  TGAAGTGGGAGGACAGAGGTCCAAGTGGGCAAGGGCAGGGGCAGTTCTTGATACAGCAGGTGACCCTGAA
  AATTCCCATTTCCATAGAGTTTGTGTTTGAATCAGGCAGTGCCCAGGCAGGAGGAAATCAAGCCCTGCCA
  AGACTGGCAGGCAGTCTACTGACCCAGGCCCTGGAGAGCCATGCTGAAGGCTTTAGAGAGCGCTTTGAGA
  AGACCTTCCAGCTGAAGGAGAAGGGCCTGAGCTCTGGCGAGCAGGTTTTGGGTCAGGCTGCCCTCAGCGG
  CCTCCTTGGTGGAATTGGCTACTTCTACGGACAAGGGCTGGTATTGCCAGACATCGGGGTGGAAGGGTCT
  GAGCAGAAGGTGGACCCAGCCCTCTTTCCACCCGTACCTCTTTTTACAGCAGTGCCCTCCCGGTCATTCT
  TCCCACGAGGCTTCCTTTGGGATGAAGGCTTTCACCAGCTGGTGGTTCAGCGGTGGGATCCCTCCCTCAC
  CCGGGAAGCCCTTGGCCACTGGCTGGGGCTGCTAAATGCTGATGGCTGGATTGGGAGGGAGCAGATACTG
  GGGGATGAGGCCCGAGCCCGGGTGCCTCCAGAATTCCTAGTACAACGAGCAGTCCACGCCAACCCCCCAA
  CCCTACTTTTGCCTGTAGCCCATATGCTAGAGGTTGGTGACCCTGACGACTTGGCTTTCCTCCGAAAGGC
  CTTGCCCCGCCTGCATGCCTGGTTTTCCTGGCTCCATCAGAGCCAGGCAGGCCCACTGCCACTATCTTAC
  CGCTGGCGGGGACGGGACCCTGCCTTACCAACCTTACTGAACCCCAAGACCCTACCCTCTGGGCTGGATG
  ACTACCCCCGGGCTTCACACCCTTCAGTAACCGAGCGGCACCTGGACCTGCGATGTTGGGTGGCACTGGG
  TGCCCGTGTGCTGACGCGGCTGGCAGAGCATCTGGGTGAGGCTGAGGTAGCTGCTGAGCTGGGCCCACTG
  GCTGCCTCACTGGAGGCAGCAGAGAGCCTGGATGAGCTGCACTGGGCCCCAGAGCTAGGAGTCTTTGCAG
  ACTTTGGGAACCACACAAAAGCAGTACAGCTGAAGCCCAGGCCCCCTCAGGGGCTCGTTCGGGTGGTGGG
  TCGGCCCCAACCTCAACTGCAGTATGTAGATGCTCTTGGCTATGTCAGTCTTTTTCCCTTGCTGCTGCGA
  CTGCTGGACCCCACCTCATCCCGCCTTGGGCCCCTGCTGGACATTCTAGCCGACAGCCGCCATCTCTGGA
  GCCCCTTTGGTTTACGCTCCCTTGCAGCCTCCAGCTCCTTTTATGGCCAGCGCAATTCAGAGCATGATCC
  CCCCTACTGGCGGGGTGCTGTGTGGCTCAATGTCAACTACCTGGCTTTGGGAGCACTCCACCACTATGGG
  CATCTGGAGGGTCCTCACCAGGCTCGGGCTGCCAAACTCCACGGTGAGCTCCGTGCCAACGTGGTAGGCA
  ATGTATGGCGCCAGTACCAGGCTACAGGCTTTCTTTGGGAGCAGTACAGTGACCGCGATGGGCGAGGCAT
  GGGCTGCCGCCCTTTCCACGGCTGGACCAGCCTTGTCTTACTGGCCATGGCTGAAGACTACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006302 unedited
  TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGAGGCGCAGGC
  GCTGGCTGGCAGGTGTCGCTAACCGGACGGTGGTCGCCAGGGCGAGAGGCGGGAGCCGGA
  GAGGACTGATGTGGGCGCAGCAGGGCACCACCCCGGGGACTCCTAAGCTCAGGCACACGT
  GTGAGCAGGGGGACGGTGTGGGTCCCTATGGCTGGGAGTTCCACGACGGCCTCTCCTTCG
  GGCGCCAACACATCCAGGATGGGGCCTTAAGGCTCACCACTGAGTTCGTCAAGAGGCCTG
  GGGGTCAGCACGGAGGGGACTGGAGCTGGAGAGTGACTGTAGAGCCTCAGGACTCAGGTA
  CTTCTGCCCTCCCTTTGGTCTCCCTGTTCTTCTATGTGGTGACAGATGGCAAGGAAGTCC
  TACTACCAGAGGTTGGGGCCAAGGGGCAGTTGAAGTTTATCAGTGGGCACACCAGTGAAC
  TTGGTGACTTCCGCTTTACACTTTTGCCACCAACCAGTCCAGGGGATACAGCCCCCAAGT
  ATGGCAGCTACAATGTCTTCTGGACCTCCAACCCAGGACTGCCCCTGCTGACAGAGATGG
  TAAAGAGTCGCCTAAATAGCTGGTTTCAGCATCGGCCCCCAGGGGCCCCCCCTGAACGCT
  ACCTCGGCTTGCCAGGATCCCTGAAGTGGGAGGACAGAGGTCCAAGTGGGCAAGGGCGGG
  GGCAGTTCTTGATACAGCAGGTGACCCTGAAAATTCCCATTTCCATAGAGATTGGGTTTG
  AATCACGCAGTGCCCAGGCAGGAGGAATTAAGCCCTGCCCAGATGGCAGGCAGTCTACTG
  ACCCCGGCCCTGGAGACCATGCTGAAGCTTTANAGACGCTCTGAAAGACTTTCACTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006302 unedited
  GAGTCGAGTTTTTTTTTTTTTTTTTTGGTTTTTCCAATTTATTTAGAAAAATAGACTCTG
  GATTCACATTCACCCCAGGGCTATGTGGGATGACAGCAAGGAGACACCTGAGATGAAATG
  AGGAAGGTTTGAATTACTGGTATCCAAGGGGCTGGGGGCAAAAGCCAGAAGCCTTTGTCC
  CTTCAGAGCCAGAGTGGCATGAGTGTCTTGGCTCCCCTCCTCTCCCTCCCTTCAGTAGTC
  TTCAGCCATGGCCAGTAAGACAAGGCTGGTCCAGCCGTGGAAAGGGCGGCAGCCCATGCC
  TCGCCCATCGCGGTCACTGTACTGCTCCCAAAGAAAGCCTGTAGCCTGGTACTGGCGCCA
  TACATTGCCTACCACGTTGGCACGGAGCTCACCGTGGAGTTTGGCAGCCCGAGCCTGGTG
  AGGACCCTNCAGATGCCCATAGTGGTGGAGTGCTCCCAAAGCCAGGTAGTTGACATTGAG
  CCACACAGCACCCCGCCAGTAGGGGGGATCATGCTCTGAAATTGCGCTGCCATAAAAGAG
  CTGGANGCTGCAAGGGAGCGTAAACCAAAGGGGCTCCAGAGATAGCGGCTGTCGGCTAAA
  ATGTCCACCANGGGCCCAAAGCCGGAATAGGTGGGGTTCACCAGTCCCACCACCAAGGGA
  AAAGACTGACATAGCCAAGAGCCTCTCCTACTGCAGTTGAGGTTGGGGCCGACCACCCAC
  CCAACCACCCCTGAAGGGGCCTGGGCTCACCTGTACTGCTTTTGGGGGGTCCCAAAGCTG
  CAAAACTCTACTTTGGGGCCAAGGAGTTTTCCAGTTCTTGTTGTCCAAGAGGAACAATGG
  CCCACTTAACCTTCCTAACTCCCCAAAGTTTGCCCCTGTTATACACGGCCCAATGCCCCC
  CAATCCAGGCCGGGCCCTCGGTCTGAGGTGTAACCCCCGGTTCATCCACCAAGGGAGGTC
  GGGGTTAAACGGGACAGGGGTCCCCCCCCAGTGAAAAGTCGGCCCCTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006302
• ORF Size: 2910 bp
• Insert Size: 2550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006302.1, NP_006293.1
• RefSeq Size: 2910
• RefSeq ORF: 2910
• Locus ID: 7841
• Domains: Glyco_hydro_63
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).