GCS1 (MOGS) (NM_006302) Human Untagged Clone

CAT#: SC318321

MOGS (untagged)-Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MOGS
• Synonyms: CDG2B; CWH41; DER7; GCS1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006302, the custom clone sequence may differ by one or more nucleotides
  ATGGCTCGGGGCGAGCGGCGGCGCCGCGCAGTGCCGGCAGAGGGAGTGCGGACAGCCGAG
  AGGGCGGCTCGGGGAGGCCCCGGGCGACGGGACGGCCGGGGCGGCGGGCCGCGTAGCACG
  GCTGGAGGAGTGGCTCTGGCCGTCGTGGTCCTGTCTTTGGCCCTGGGTATGTCGGGGCGC
  TGGGTGCTGGCGTGGTACCGTGCGCGGCGGGCGGTCACGCTGCACTCCGCGCCTCCTGTG
  TTGCCTGCCGACTCCTCCAGCCCCGCCGTGGCCCCGGACCTCTTCTGGGGAACCTACCGC
  CCTCACGTCTACTTCGGCATGAAGACCCGCAGCCCGAAGCCCCTCCTCACCGGACTGATG
  TGGGCGCAGCAGGGCACCACCCCGGGGACTCCTAAGCTCAGGCACACGTGTGAGCAGGGG
  GACGGTGTGGGTCCCTATGGCTGGGAGTTCCACGACGGCCTCTCCTTCGGGCGCCAACAC
  ATCCAGGATGGGGCCTTAAGGCTCACCACTGAGTTCGTCAAGAGGCCTGGGGGTCAGCAC
  GGAGGGGACTGGAGCTGGAGAGTGACTGTAGAGCCTCAGGACTCAGGTACTTCTGCCCTC
  CCTTTGGTCTCCCTGTTCTTCTATGTGGTGACAGATGGCAAGGAAGTCCTACTACCAGAG
  GTTGGGGCCAAGGGGCAGTTGAAGTTTATCAGTGGGCACACCAGTGAACTTGGTGACTTC
  CGCTTTACACTTTTGCCACCAACCAGTCCAGGGGATACAGCCCCCAAGTATGGCAGCTAC
  AATGTCTTCTGGACCTCCAACCCAGGACTGCCCCTGCTGACAGAGATGGTAAAGAGTCGC
  CTAAATAGCTGGTTTCAGCATCGGCCCCCAGGGGCCCCCCCTGAACGCTACCTCGGCTTG
  CCAGGATCCCTGAAGTGGGAGGACAGAGGTCCAAGTGGGCAAGGGCAGGGGCAGTTCTTG
  ATACAGCAGGTGACCCTGAAAATTCCCATTTCCATAGAGTTTGTGTTTGAATCAGGCAGT
  GCCCAGGCAGGAGGAAATCAAGCCCTGCCAAGACTGGCAGGCAGTCTACTGACCCAGGCC
  CTGGAGAGCCATGCTGAAGGCTTTAGAGAGCGCTTTGAGAAGACCTTCCAGCTGAAGGAG
  AAGGGCCTGAGCTCTGGCGAGCAGGTTTTGGGTCAGGCTGCCCTCAGCGGCCTCCTTGGT
  GGAATTGGCTACTTCTACGGACAAGGGCTGGTATTGCCAGACATCGGGGTGGAAGGGTCT
  GAGCAGAAGGTGGACCCAGCCCTCTTTCCACCCGTACCTCTTTTTACAGCAGTGCCCTCC
  CGGTCATTCTTCCCACGAGGCTTCCTTTGGGATGAAGGCTTTCACCAGCTGGTGGTTCAG
  CGGTGGGATCCCTCCCTCACCCGGGAAGCCCTTGGCCACTGGCTGGGGCTGCTAAATGCT
  GATGGCTGGATTGGGAGGGAGCAGATACTGGGGGATGAGGCCCGAGCCCGGGTGCCTCCA
  GAATTCCTAGTACAACGAGCAGTCCACGCCAACCCCCCAACCCTACTTTTGCCTGTAGCC
  CATATGCTAGAGGTTGGTGACCCTGACGACTTGGCTTTCCTCCGAAAGGCCTTGCCCCGC
  CTGCATGCCTGGTTTTCCTGGCTCCATCAGAGCCAGGCAGGCCCACTGCCACTATCTTAC
  CGCTGGCGGGGACGGGACCCTGCCTTACCAACCTTACTGAACCCCAAGACCCTACCCTCT
  GGGCTGGATGACTACCCCCGGGCTTCACACCCTTCAGTAACCGAGCGGCACCTGGACCTG
  CGATGTTGGGTGGCACTGGGTGCCCGTGTGCTGACGCGGCTGGCAGAGCATCTGGGTGAG
  GCTGAGGTAGCTGCTGAGCTGGGCCCACTGGCTGCCTCACTGGAGGCAGCAGAGAGCCTG
  GATGAGCTGCACTGGGCCCCAGAGCTAGGAGTCTTTGCAGACTTTGGGAACCACACAAAA
  GCAGTACAGCTGAAGCCCAGGCCCCCTCAGGGGCTCGTTCGGGTGGTGGGTCGGCCCCAA
  CCTCAACTGCAGTATGTAGATGCTCTTGGCTATGTCAGTCTTTTTCCCTTGCTGCTGCGA
  CTGCTGGACCCCACCTCATCCCGCCTTGGGCCCCTGCTGGACATTCTAGCCGACAGCCGC
  CATCTCTGGAGCCCCTTTGGTTTACGCTCCCTTGCAGCCTCCAGCTCCTTTTATGGCCAG
  CGCAATTCAGAGCATGATCCCCCCTACTGGCGGGGTGCTGTGTGGCTCAATGTCAACTAC
  CTGGCTTTGGGAGCACTCCACCACTATGGGCATCTGGAGGGTCCTCACCAGGCTCGGGCT
  GCCAAACTCCACGGTGAGCTCCGTGCCAACGTGGTAGGCAATGTATGGCGCCAGTACCAG
  GCTACAGGCTTTCTTTGGGAGCAGTACAGTGACCGCGATGGGCGAGGCATGGGCTGCCGC
  CCTTTCCACGGCTGGACCAGCCTTGTCTTACTGGCCATGGCTGAAGACTAC
  
• Restriction Sites: Please inquire
• ACCN: NM_006302
• ORF Size: 2514 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006302.2, NP_006293.2
• RefSeq Size: 2910
• RefSeq ORF: 2514
• Locus ID: 7841
• Domains: Glyco_hydro_63
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).