LASP1 (NM_006148) Human Untagged Clone

CAT#: SC116276

LASP1 (untagged)-Human LIM and SH3 protein 1 (LASP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LASP1
• Synonyms: Lasp-1; MLN50
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116276 sequence for NM_006148 edited (data generated by NextGen Sequencing)
  ATGAACCCCAACTGCGCCCGGTGCGGCAAGATCGTGTATCCCACGGAGAAGGTGAACTGT
  CTGGATAAGTTCTGGCATAAAGCATGCTTCCATTGCGAGACCTGCAAGATGACACTGAAC
  ATGAAGAACTACAAGGGCTACGAGAAGAAGCCCTACTGCAACGCACACTACCCCAAGCAG
  TCCTTCACCATGGTGGCGGACACCCCGGAAAACCTTCGCCTCAAGCAACAGAGTGAGCTC
  CAGAGTCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTA
  GTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATA
  AAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAG
  CCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAG
  CCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCC
  CAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCA
  GGTGGTGGCGGGAAGCGGTACCGCGTGGTGTATGACTACAGCGCCGCCGACGAGGACGAG
  GTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATG
  TACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTACGTGGAGGCC
  ATCTGA
  
  Clone variation with respect to NM_006148.2
  626 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006148 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTCCAGCCGCCGTCGC
  TGCTGCCTGTGTAGTTGCAGCCGCGGCCGCCTCCCGCCAGCTCGCCTCGGGGAACAGGAC
  GCGCGTGAGCTCAGGCGTCCCCGCCCCAGCTTTTCTCGGAACCATGAACCCCAACTGCGC
  CCGGTGCGGCAAGATCGTGTATCCCACGGAGAAGGTGAACTGTCTGGATAAGTTCTGGCA
  TAAAGCATGCTTCCATTGCGAGACCTGCAAGATGACACTGAACATGAAGAACTACAAGGG
  CTACGAGAAGAAGCCCTACTGCAACGCACACTACCCCAAGCAGTCCTTCACCATGGTGGC
  GGACACCCCGGAAAACCTTCGCCTCAAGCAACAGAGTGAGCTCCAGAGTCAGGTGCGCTA
  CAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGA
  GCTCCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTT
  TGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTC
  ACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGAC
  CAGTGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTTCTATGGTGGGCT
  ACAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGGTGGCGGGAAAG
  CGTACCGGGTGGTGTATGACTACCAGCGCCGNCGACGAAGACGAGGTCTTCTTNCAGNAC
  GGGGACACCATCGNTCACGTGCANCAAATCNACNACGGTTGGATGTCCGGGACGGTGGAC
  N
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006148 unedited
  TCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAAATATACTTTTATTTGAGTCACCAGGA
  GAAAGATTCACTTGTGGTTCACTTCAAACGTTCAGAATCATAACAGGCCAGAAAGGTTTG
  ATCCCGAGCACAAGCCCACGAGGGAGGGGACCAAAACAGACCAAAATGAGACAACAACCC
  CATATAAAAAGATGAACTGGCGGCTTCACACACTCACACACATACACATACACACGGATG
  AAATGTTTGGACAGAGGCAAATTTCACGTGGTCATTTCTGTTTCTTTTTAAATACATGTT
  TGTAGGGTGGTATTTTGTTTTTTCCAGCTATAAAAAAAGGCCCAAAAGTGCATGTGTGAG
  GGGGGAAAGGCANAAATTAAGCAATAAAGTCATTTTCCCTGGAGGGACATGAGAGGGAGA
  AAACAGGAGGCAGTGCTGGGAGAACGCACTCTCCTCACCACTGGGCTTCTTGTTATTCTT
  AGTATTGGTCCACAAAAGTTATATTCAACTTCTAGCTTTGATGCCTTCTTTCCTGAGATT
  AAATGAGCTGAAAGACCTCTGTGAACTGTAGAGAAGACCAGGGGCTTACCCCAACCCAGC
  CCAGCCCTCAAGCCTCTGTGCTCTCTAAGGATGAACGTTTTGGTAAAGACAGACGCCCAG
  CACCCCCCGGTACTAAGTACCATTGTGACAGGTCCTCCTCTCTCTGGGGTGGGAAAAAAA
  CGCCCCTATTTTAGACAGGACACGAAGGGAGGCCTCGCCCAGATCCCTGATGCTTTGCCT
  AATTGGAGGAAATTACCTGATGAAACACGCTGTTTTGTTGGCCTCCTTCACTCACATTTC
  CAACAAGGTCTTAAAGGGTGGGCCCGACCTGGCCCCAATCCACTGGCTTGAAACAAGGAA
  CAAAGCTACCGCCCCCAATCCAAAAACCTGCCCCCCACCCCCAAGCCATAAAGAATCCAT
  GCCCCATACTGCGCCAAGAAAGAAGCTACAAGCCCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006148
• ORF Size: 786 bp
• Insert Size: 4310
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006148.1, NP_006139.1
• RefSeq Size: 3846
• RefSeq ORF: 786
• Locus ID: 3927
• Domains: NEBU, SH3, LIM
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]
  Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.