BPNT1 (NM_006085) Human Untagged Clone

CAT#: SC116312

BPNT1 (untagged)-Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BPNT1
• Synonyms: HEL20; PIP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116312 sequence for NM_006085 edited (data generated by NextGen Sequencing)
  ATGGCTTCCAGTAACACTGTGTTGATGCGGTTGGTAGCCTCCGCATATTCTATTGCTCAA
  AAGGCAGGAATGATAGTCAGACGTGTTATTGCTGAAGGAGACCTGGGTATTGTGGAGAAG
  ACCTGTGCAACAGACCTGCAGACCAAAGCTGACCGATTGGCACAGATGAGCATATGTTCT
  TCATTGGCCCGGAAATTCCCCAAACTCACAATTATAGGGGAAGAGGATCTGCCTTCTGAG
  GAAGTGGATCAAGAGCTGATTGAAGACAGTCAGTGGGAAGAAATACTGAAGCAACCATGC
  CCATCGCAGTACAGTGCTATTAAAGAAGAAGATCTCGTGGTCTGGGTTGATCCTCTGGAT
  GGAACCAAGGAATATACCGAAGGTCTTCTTGACAATGTAACAGTTCTTATTGGAATTGCT
  TATGAAGGAAAAGCCATAGCAGGAGTTATTAACCAGCCATATTACAACTATGAGGCAGGA
  CCAGATGCTGTGTTGGGGAGGACAATCTGGGGAGTTTTAGGTTTAGGCGCCTTTGGGTTT
  CAGCTGAAAGAAGTCCCTGCTGGGAAACACATTATCACAACTACTCGATCCCATAGCAAC
  AAGTTGGTTACTGACTGTGTTGCTGCTATGAACCCCGATGCTGTGCTGCGAGTAGGAGGA
  GCAGGAAATAAGATTATTCAGCTGATTGAAGGCAAAGCCTCTGCTTATGTATTTGCAAGT
  CCTGGTTGTAAGAAGTGGGATACTTGTGCTCCAGAAGTTATTTTACATGCTGTGGGAGGC
  AAGTTAACCGATATCCATGGGAATGTTCTTCAGTACCACAAGGATGTGAAGCATATGAAC
  TCTGCAGGAGTCCTGGCCACACTGAGGAATTATGACTACTATGCAAGCCGAGTTCCAGAA
  TCTATTAAAAATGCACTTGTTCCTTAA
  
  Clone variation with respect to NM_006085.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006085 unedited
  TGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGGGTCTA
  CGATAACGCGCTTTTGCTCCTCCTGAATGTCTTTGGTCCAACGTTGTTCCAGAGTGTACC
  ATGGCTTCCAGTAACACTGTGTTGATGCGGTTGGTAGCCTCCGCATATTCTATTGCTCAA
  AAGGCAGGAATGATAGTCAGACGTGTTATTGCTGAAGGAGACCTGGGTATTGTGGAGAAG
  ACCTGTGCAACAGACCTGCAGACCAAAGCTGACCGATTGGCACAGATGAGCATATGTTCT
  TCATTGGCCCGGAAATTCCCCAAACTCACAATTATAGGGGAAGAGGATCTGCCTTCTGAG
  GAAGTGGATCAAGAGCTGATTGAAGACAGTCAGTGGGAAGAAATACTGAAGCAACCATGC
  CCATCGCAGTACAGTGCTATTAAAGAAGAAGATCTCGTGGTCTGGGTTGATCCTCTGGAT
  GGAACCAAGGAATATACCGAAGGTCTTCTTGACAATGTAACAGTTCTTATTGGAATTGCT
  TATGAAGGAAAAGCCATAGCAGGAGTTATTAACCAGCCATATTACAACTATGAGGCAGGA
  CCAGATGCTGTGTTGGGGAGGACAATCTGGGGAGTTTTAGGTTTAGGCGCCTTTGGGTTT
  CAGCTGAAAGAAGTCCCTGCTGGGAAACACATTATCACAACTACTCGATCCCATAGCAAC
  AAGTTGGTTACTGACTGTGTTGCTGCTATGAACCCCGATGCTGTGCTGCGAGTANGAGGA
  GCANGAAATAAGATTATTCAGCTGATTGAAAGCAAAGCCTCTGCTTATGTATTTGCAAGT
  CCTGGTTGTAAGAAGTGGGATACTTGTGCTCCAGAAGTATTTACATGCTGTGGGAGGCAA
  GTTACCGATATCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006085 unedited
  GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTGANACAGGGCTTAACTCCTG
  TCACTCAGGCTGGAGTGCAGTGGCACGATCTCAGCCCACTGCAACCTCCGCCTTCCGGGC
  TCAAGAGATTCTTCTGCTTCAGCCTCTCAAGTAGCTGGGATGACAGGCGCATGACAGGAT
  GCCCAGTTAATTTGTATTTTTGTAGAGATGGGGTCTCACGATATTGCCCAGGCTGGTCTC
  AAACTCCTGAGCTCAAGTGATCCACCTGCCTCGGCCTCCCAAAGTGCCGGGATTACAGGC
  ATGAGCCACCGCGCCCGGCCAAATGAAACTTTCCCTTAAGGAACAAGTGCATTTTTAATA
  GATTCTGGAACTCGGCTTGCATAGTAGTCATAATTCCTCAGTGTGGCCAGGACTCCTGCA
  GAGTTCATATGCTTCACATCCTTGTGGTACTGAAGAACATTCCCATGGATATCGGTTAAC
  TTGCCTCCCACAGCATGTAAAATAACTTCTGGAGCACAAGTTCCCACTTCTTACAACCAG
  GACTTGCAAATACATAACCAGAGGCTTTGCCTTCAATCAACTGAATAATCTTATTTCCTT
  GCTCTCCTACTCCCAGCACAGCATCCGGGGTTCACTACCAGCACCCCAGCCACCACCCAA
  CTTGTTCCCCCTGGGATCGACCATGTTTCGATACGGGCTTTTCCCACCAGGGCCCTCCCT
  TTCACCTGAAACCCCAAAGGGCCCCTAATACCTAAAACTCCCCCCCATCCGCCCTTCCGT
  ACTCAATATCCTGGTTCCTGCTTCACCCGCCCCATACCGCCGCGTACCTACATCCAGCGT
  GGGCCGTTTCTTTTTAACATTCCTTACCAAAAATCCGCCACGTGCCCAAACAACCCCCCC
  TTCTTCCTCCCTCCCCTCCCAGTCCACTCCTAACTCCCACCACTCTTTTGTCCACTCCAC
  TCTCGTCGCGGCGCCCGGTCTTCCGCTTTCCGCCGCCTCCAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006085
• ORF Size: 786 bp
• Insert Size: 1400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006085.3, NP_006076.3
• RefSeq Size: 2451
• RefSeq ORF: 786
• Locus ID: 10380
• Domains: inositol_P
• Protein Pathways: Sulfur metabolism
• Gene Summary: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.